... damage tothe circuit (if the pacemaker is out ofthetreatment field) by the electromagnetic field is the proposed mechanism of damage Therefore, while there is no consensus for a safe threshold of ... http://www.ro-journal.com/content/6/1/16 Page of Figure PET Response totreatmentof an intracardiac metastases in the R ventricle and atrium The top panel demonstrates a PET-CT scan ofthe hypermetabolic tumor mass prior totreatment ... additional boost of 10 to 15 Gy for adequate control[3,15] III Cardiac toxicity is dose-limiting in thetreatmentof cardiac metastases with external beam radiation The dose tolerance ofthe pericardium...
... resection ofthe primary tumor Proton therapy was found to be effective in treating RCC metastasis tothe ciliary body in settings in which other treatment modalities failed Introduction Renalcellcarcinoma ... peripheral iridotomy to lower the intraocular pressure The results of a further metastatic workup were consistent with a stage IV RCC that was ofthe clear cell type (Figure 3) and that involved the ciliary ... injections of bevacizumab) shows that the red mass had grown (d) SLE photograph delineates the mass-lens adhesions prior to proton beam radiotherapy (e) SLE photograph ofthe right eye after proton...
... history ofrenal mass, while the rest ofthe patients had previously undergone nephrectomy at a time interval ranging from eight to 18 years prior tothe diagnosis ofthemetastatic lesion tothe ... cases there was a history of nephrectomy for RCC (one month to 17 years before the diagnosis ofthe ocular metastatic lesion) In two cases there was no mention ofthe previous medical history The ... Peckham S: Renal medullary carcinomametastatictothe scalp Am J Dermatopathol 2011, 33(1):e11-13 74 Kato S, Nishino Y, Ito Y, Takeuchi T, Ban Y, Uno H: Renalcellcarcinomametastatictothe ovary...
... growth ofrenalcellcarcinomaThe diagnosis ofrenalcellcarcinoma metastasizing to solitary fibrous tumor is paramount in this case as the metastasis was the first confirmation ofrenalcellcarcinoma ... (PAX2) cell features in the background of a delicate vascular network (Figures 3b and 3c) To further explore the nature of these cells, a battery of immunohistochemical staining was performed The cells ... http://www.jmedicalcasereports.com/content/5/1/248 Page of 11 Bohn OL, De las Casas LE, Leon ME: Tumor -to- tumor metastasis Renalcellcarcinomametastaticto papillary carcinomaof thyroid: report of a case and review ofthe literature...
... the administration of immunosuppressants changed the immunological equilibrium and probably triggered the pulmonary metastatic malignant growth of dormant tumor cells from the primary renalcarcinoma ... for the surveillance of localized renalcellcarcinoma based on the patterns of relapse after nephrectomy J Urol 2004, 172:58-62 Penn I: Cancer in renal transplant recipients Adv Ren Replace Ther ... 1957, the immune system protects the host against tumor development by recognizing and eliminating transformed cells, therefore, the dysfunction ofthe immune system leads to increased risk of cancer...
... [41] To our knowledge this is the first study which compare the use of a HA and ofthe ISC in the enucleoresection of RCC The recent evidence related tothe NSS capable, in selected cases, to offer ... Looking tothe future, minimally invasive surgery will further drive the use of topical HA in the urologic field They offer promising employ in the laparoscopic and robotic surgery to avoid the intricacy ... [39] Therefore, it is crucial to get a better understanding ofthe genesis of those reactions Ahead of its time are, on one hand, the recently applications of HAs in the premature rupture of membranes...
... compared tothe other cell lines) We then tested the effect ofthe arginase inhibition by norNOHA (2 mM) on cell proliferation at 24, 48, and 72 hours Growth of CL-19, which had the highest level of ... effects on the growth rates ofthe low arginase producer cell lines CL-2 (P = 0.14) and Renca (P = 0.07) Cell viability ofthe cells was > 95% at the different points and conditions ofthe experiments ... supernatants of murine renalcellcarcinomacell lines and determine their effect on cell proliferation In adult mammals, the majority of endogenous L-arginine is synthesized from citrulline in the kidney...
... is a picture ofrenal ultrasound It shows echo-dense area in therenal area, suggestive of a renal tumour RenalCellCarcinoma in the form of hoarseness or calverial metastasis of which only ... been reported [3,4] Renalcellcarcinoma represents a heterogenous group of tumors, the most common of which is clear cell adenocarcinoma RCC accounts for 3% of adult tumors The incidence has increased ... be used instead ofthe pathologic stage to determine the risk of recurrence [8] Conclusion Renalcellcarcinoma presents with various clinical features Atypical presentations of RCC should be...
... The von Hippel-Lindau tumor suppressor protein sensitizes renalcellcarcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factor-kappaB-dependent antiapoptotic ... directly to WNT, preventing its binding tothe FZ receptor [58], and the Dickkopf (DKK) proteins, which bind tothe Low-density lipoprotein receptor-related protein (LRP5)-LRP6 component ofthe Wnt ... cancers [31] and occur in 45 to 90% of sporadic RCCs [4,32,33] Inactivation ofthe 3p25 TSG VHL is of critical importance tothe pathogenesis of ccRCC and occurs in up to 86% of tumors [34] Although...
... metastases tothe lung, 36% to soft tissues, 20% to bone, 18% to liver, 8% to cutaneous sites and 8% tothe central nervous system [2] Approximately 15% ofrenalcell carcinomas metastasize tothe head ... grade clear cellcarcinomaofthe left kidney with extension into the superior perirenal fat but not into therenal sinus and with no microvascular infiltration The maximal dimension ofthe tumour ... Disappearance ofmetastaticrenalcellcarcinomatothe base ofthe tongue after systemic administration of interferon-α Eur Urol 1993, 24:297-299 Page of (page number not for citation purposes) Journal of...
... Kato SN: Renalcellcarcinomatothe base of tongue: a case report Hinyokika Kiyo 2004, 50(11):791-793 Phillips CK, Taneja SS: The role of lymphadenectomy in thesurgical management ofrenalcell ... test- Figure to tumor ulceration of secondarycarcinoma ;cell infiltrationmucosal epithelium noted RenalcellRenalcell carcinoma; ulceration of mucosal epithelium noted secondary to tumor cell infiltration ... surrounded of rich cell carcinoma; epithelial cellular network2shown with clear vascular network Histologic featuresin arenalcytoplasm and hyperchromatic Histologic features ofrenalcell carcinoma; ...
... characteristics to intervene directly with the use ofsurgicaltreatment THERAPY Thetreatmentofrenalcellcarcinoma depends on the final pathologic and radiologic staging ofthe patient Essentially, in the ... : The comparison ofthe model with the predictor ofthe Karakiewicz nomogram only with the one with predicators of both the Kattan nomogram and the Karakiewicz nomogram b : The comparison ofthe ... present to clinicians either in the asymptomatic setting (screening) or with a variety of symptoms that may be suggestive of either the local extension ofthe tumour, or the systemic spread of the...
... incidence of cutaneous metastasis from all urologic malignancies is 1.1% to 2.5% [8] The relative incidences of metastasis tothe skin among gentitourinary cancers are 3.4% to 4.0% for renalcell carcinoma, ... all the subtypes of testicular germ cell tumor, choriocarcinoma is the most aggressive with highly metastatic potential [10] The cutaneous metastasis as the first sign ofmetastatic choriocarcinoma ... helped in the clinical work as well as the literature review STP and SKL were responsible for editorship ofthe manuscript CKC is the head ofthe department who supervised all the steps ofthe work...
... one report in the literature describing the use of cardiac surgery to remove a hepatocellular carcinoma that had metastasized tothe right ventricle [4] Management of metastasis tothe heart is ... patch to direct inferior vena cava flow into the lower part ofthe RPA A mm fenestration was created to decompress the right side circulation Cardiopulmonary bypass was weaned off smoothly and the ... the immediate postoperative course was uneventful The patient was extubated on the postoperative day 2, and she was transferred to ward on the postoperative day Page of Shortness of breath and tachypnea...
... incision of about cm is made from the top end ofthe 11th rib tothe border ofthe rectus abdominis Page of Figure Thesurgical procedure ofthe A method (No.2) It is possible to remove the flank ... incidence of peritoneal injury, rate of conversion to laparotomy, and perioperative complications The Figure Thesurgical procedure ofthe A method (No.3) The LAPDISC is placed in the incision to insert ... opportunity to perform it in order to stop massive bleeding On the other hand, one ofthe disadvantages ofthe A method is larger size ofthe incision The incision, which is about cm, is larger than the...
... scar at the previous frontotemporal lesion Figure Photomicrographs ofsurgical pathology specimens (AB) Photomicrograph of left parotid mass showing tumor cells of similar cytology tothe original ... one year of therapy [17] In general, chemotherapy, if considered at all, is reserved for metastatic EPC On the other hand, the role of radiation therapy in EPC seems to have changed over the years ... five years of follow-up Based on the literature, the role of chemotherapy in thetreatmentof EPC remains unclear Orphan cases with good responses to 5-fluorouracil [14], thiotepa and Cytoxan (cyclophosphamide)...
... due tothe adjuvant effects of high-dose IL-2 We further characterized the effector CD8+ T cells in whole PBMC and found that there was an increase in CD107a, a marker of degranulation and cytotoxic ... Nephrectomy and interleukin-2 for metastatic renal- cellcarcinoma N Engl J Med 2001, 345:1711-1712 Diner EK, Linehan M, Walther M: Response of papillary renalcellcarcinoma in a solitary kidney to ... analysis, or interpretation ofthe data, or in the writing ofthe report They also had no access tothe raw Page of 11 (page number not for citation purposes) Journal of Translational Medicine...
... Department of Surgery, University of Athens, Aretaieion Hospital, 78, V Sofias av, 115 28, Athens, Greece, 2Second Department of Surgery, University of Athens, Aretaieion Hospital, 78, V Sofias av, ... extension of involvement Furthermore, an approach for drainage of abscesses can be made on CT results However, sometimes an exploratory laparotomy is necessary to reveal the cause Nonetheless, ... from the patient for publication of this case report and accompanying images A copy ofthe written consent is available for review by the Editor-in-Chief of this journal Competing interests The...
... challenge; the disease extends into the RA with various degrees of infiltration and adherence into the wall of IVC Under those circumstances the use of Total Circulatory Arrest (TCA) has become the ... reflecting the preoperative compromise health status of this group of patients and possibly the use of circulatory arrest According to Cooper et al [18] the use of TCA increases up to 40% the risk of ... Figure Renalcellcarcinoma invading the upper pole ofthe kidney with tumor propagating into the IVC Page of Figure Direct removal ofthe tumor mass Transient inotropic support by means of Dopamine...
... fever, or symptoms ofmetastatic disease and other rare phenomena [2] Approximately 20% to 30% of patients with renalcellcarcinoma present with metastatic disease, and 20% to 40% of patients ... treating metastatic patients Removal ofthe malignant kidney may be of palliative benefit in some settings ofmetastaticrenalcellcarcinoma [5] There have been studies to demonstrate that the benefits ... little proven impact on the survival of patients with advanced renalcellcarcinoma compared to a variety of other options with less toxicity [6] There have been case reports in the literature that...