summary of major changes recist 1 0 to recist 1 1
Báo cáo khoa học: Coordination of three and four Cu(I) to the a- and b-domain of vertebrate Zn-metallothionein-1, respectively, induces significant structural changes doc
... 200 0 10 00 relative intensity 600 0 400 0 relative intensity 50 40 700 0 500 0 relative intensity 60 B Dolderer et al 500 0 400 0 300 0 200 0 10 00 equivalents Cu(I) 0 mole equiv of Cu(I) mole equiv of Cu(I) ... ( 200 7) 2349–2362 ª 200 7 The Authors Journal compilation ª 200 7 FEBS 3 50 400 2 50 300 3 50 400 / nm 23 51 Murine Cu(I)a- and Cu(I)b-MT -1 domains A B equivalents Cu(I) 300 0 equivalents Cu(I) 200 0 10 00 ... function of 0. 52 ± 0 .13 A2 and RMSD values of 1. 04 ± 0 .12 A and 1. 51 ± 0 .18 A for the backbone and all heavy atoms, respectively Fig 1H-1H-NOESY spectra of Zn4aMT (red) superimposed with that of ZnxCu3aMT...
Ngày tải lên: 07/03/2014, 09:20
REGIONAL OFFICE OF EDUCATION #1 NOTES TO FINANCIAL STATEMENTS JUNE 30, 2009 SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Continued)_part1 pdf
... Date 12 - 31- 08 12 - 31- 07 12 - 31- 06 Three-Year Trend Information for the Regular Plan Percentage Annual Pension ofAPC Net Pension Cost (APC) Contributed Obligation 22 ,14 5 10 0% $0 22,933 10 0% o 17 ,768 ... www.adultpdf.com 35 REGIONAL OFFICE OF EDUCATION #1 NOTES TO FINANCIAL STATEMENTS JUNE 30, 200 9 Note 11 - DUE FROM WCR At June 30, 200 9, the Regional Office of Education #1 was due $12 ,4 90 from the West Central ... 243,5 81 116 23, 3 10 17 ,758 2 61, 339 266,775 $ 17 ,762 23,772 2 91, 475 297,485 Total accumulated depreciation Governmental activity capital assets, net Increases Ending Balances 17 ,874 284,649 30, 7 10 ...
Ngày tải lên: 19/06/2014, 19:20
REGIONAL OFFICE OF EDUCATION #1 NOTES TO FINANCIAL STATEMENTS JUNE 30, 2009 SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Continued)_part2 ppt
... 30, 200 9 (16 4) (66) 13 ,389 Net changes in fund balances 20, 000 80 ,18 4 4,378 16 2 12 1,667 307 4, 218 4, 702 80 ,11 8 71, 5 80 2,577 4,277 402 70, 702 234 17 3,398 16 4 $ Student Assistance Program 70, 700 ... 259,625 258, 717 908 17 2,4 90 9 ,16 6 14 4,6 80 9,724 1, 304 1, 303 70, 7 01 50, 353 7 ,02 7 11 ,293 2 ,02 8 See accompanying Independent Auditor's Report 43 16 4 202 (16 ,06 8) Fund balance - July I, 200 8 Fund balance ... LIPLEPS $ 17 ,674 92,864 24, 518 $ 84 ,06 8 7,864 19 ,2 61 5,934 20, 0 01 17,689 1, 02 2 976 13 5 ,05 6 20, 000 $ Regional Office of Prevention Administrators Effectiveness Set\1ices Academy $ 767 5 81 (2,679) 13 6...
Ngày tải lên: 19/06/2014, 19:20
REGIONAL OFFICE OF EDUCATION #1 NOTES TO FINANCIAL STATEMENTS JUNE 30, 2009 SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Continued)_part3 pdf
... 6,5 21 11, 01 7 11 ,898 21, 418 10 ,574 Fund balance - July 1, 200 8 $ 998 8 81 ( 10 ,844) Net changes in fund balances Fund balance - June 30, 200 9 $ $ 2 ,00 0 2 ,00 0 2 ,00 0 I 2 ,0 01 Supervisory Fund $ $ 14 , 609 ... Payment to other governmental units Other Total expenditures Net change in fund balances Variance Positive (Negative) 13 0 , 10 2 15 (15 ) 13 0 , 10 1 13 0 , 10 4 (3) 13 0 , 10 1 13 0 ,11 9 (18 ) (17 ) ,;$:: ==, :( ~17 : ... 14 , 609 14 ,268 3 41 1,6 80 1, 0 61 619 852 13 2 ,0 21 1 ,15 6 Bus Driver Fees See accompanying Independent Auditor's Report 51 7, 519 724 9,232 2,5 30 378 17 ,04 6 17 ,04 0 3 ,18 4 16 ,04 8 $ $ 3,344 II 4,225 4, 214 14 ,727...
Ngày tải lên: 19/06/2014, 19:20
An analysis of key changes under ucp 600 compared to ucp 500 and recommendations for better ucp 600 application.doc
... beneficiary to another at the request of the first beneficiary Chapter Key Changes under UCP 600 compared to UCP 500 2 .1 Changes in Structure of UCP 600 compared to UCP 500 The new rules UCP 600 is ... terms For example, if he quoted “ 10 ,00 0 FOB Haiphong – Incoterms 200 0” and the credit states “ 10 ,00 0 CIF Hong Kong –Incoterms 200 0” he will naturally not be able to recover the freight and insurance ... assignment of proceeds 2 .1. 1 UCP 500 articles not included in UCP 600 There are articles of UCP 500 that have not covered in UCP 600 Article and part of Article refer to revocable letters of credit...
Ngày tải lên: 27/10/2012, 16:40
An investigation into the reality of teaching and learning speaking skills to the 2nd year non-major english students at pre-intermediate level of proficiency at hanoi university of industry
... Approach of Speaking Skill 1. 3 Problems with Speaking and Speaking activities 10 1. 3 .1 Problems with Speaking 1. 3.2 Problems with Speaking Activities 10 11 1. 4 Motivation 12 1. 4 .1 Definition of Motivation ... Conditions of Applying CLT 1. 1.4 Using CLT in Teaching Speaking Skills 1. 1.5 Factors Affecting CLT Application 1. 2 Speaking Skill 1. 2 .1 Concepts of Speaking 1. 2.2 Characteristics of Speaking 1. 2.3 ... Methods of the study VI Design of the study PART TWO: DEVELOPMENT Chapter one Literature review 1. 1 Communicative Language Teaching (CLT) 1. 1 .1 Concept of CLT 1. 1.2 Characteristics of CLT 1. 1.3 Conditions...
Ngày tải lên: 07/11/2012, 14:50
Tài liệu AN INTRODUCTION TO THE HISTORY OF WESTERN EUROPE PART 1 pptx
... Suzerains of the Counts of Champagne 11 3 11 France at the Close of the Reign of Philip Augustus 12 9 12 The Plantagenet Possessions in England and France 14 1 13 Europe about A.D 10 00 15 2 15 3 14 Italian ... 14 Italian Towns in the Twelfth Century 17 5 15 Routes of the Crusaders 19 0 19 1 16 The Crusaders' States in Syria 19 3 17 Ecclesiastical Map of France in the Middle Ages 205 18 Lines of Trade and ... they claim to begin and end their books at precise dates We find histories of Europe from 476 to 918 , from 12 70 to 14 92, as if the accession of a capable German king in 918 , or the death of a famous...
Ngày tải lên: 16/02/2014, 23:20
Tài liệu Báo cáo khoa học: Steady-state and time-resolved fluorescence studies of conformational changes induced by cyclic AMP and DNA binding to cyclic AMP receptor protein from Escherichia coli ppt
... Species h (ns) CRPW13F CRPW85A CRPW13F(cAMP)2 CRPW85A(cAMP)2 20. 5 15 .3 22 .1 10. 45 v2 r (0) 2.4 1. 8 6.9 3 .0 0.23 0. 21 0. 23 0. 23 0. 02 0. 02 0. 03 0. 03 1. 222 1. 05 5 1. 03 6 1. 146 supported recently ... 0. 28 0 .11 0 . 10 0. 06 0. 06 0. 25 8 .1 2.5 2.4 2 .0 1. 5 4.3 26.6 18 .7 18 .4 20. 2 20. 3 20 .1 3.9 0. 8 0. 8 0. 6 0. 5 1. 2 indicates an increase in the mobility of helix A of the protein As Trp13 ... CRPW13F(cAMP)4 CRPW13FICAP CRPW13Flac CRPW13Fgal 5.83 5.59 5.99 5.55 5.85 5.85 4.42 1. 55 1. 54 2 . 10 2.23 2 .17 24.2 72.3 74.3 62.2 61. 9 62.9 ặRổ (A) ặEổ (%) 0. 50 0. 31 0. 42 0. 25 0 .16 0 .12 ...
Ngày tải lên: 20/02/2014, 23:20
Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf
... 0. 20 ^ 0. 02 (3)* 0 .17 ^ 0. 02 (3)* 0. 65 ^ 0 .11 (3) 1. 17 ^ 0 .16 (3) 1. 06 ^ 0. 03 (3) 0 .12 ^ 0. 01 (3)* 0 .18 ^ 0. 03 (3)* 0. 61 ^ 0. 08 (3)* 0. 77 ^ 0. 01 (3) 0. 21 ^ 0. 05 (3)* 0 .13 ^ 0. 01 (3)* 0 . 10 ^ 0. 02 ... (4) * 90. 7 ^ 5.8 (3) 87.3 ^ 15 .5 (3) 10 4.8 ^ 5.9 (3) 74.5 ^ 9 .1 (3) † 23.8 ^ 2 .1 (3) *† 10 1 .0 ^ 5.2 (3) † 81. 6 ^ 9.8 (3) 1. 3 1. 1 1. 2 1. 1 0. 9 1. 7 1. 1 1. 3 0. 9 1. 5 1. 2 1. 4 1. 5 0. 7 1. 6 1. 0 6278 M ... or 0. 2% Triton X - 10 0 The final concentrations of uPA was 0 .12 5 mg·mL 21 (2 .15 nM ), of PAI -1 in the range 0 10 mg·mL 21 (0 18 5 nM ), and of vitronectin in the range 0 15 mg·mL 21 (0 – 200 nM ) Upon...
Ngày tải lên: 22/02/2014, 07:20
Using a Spend Analysis to Help Identify Prospective Air Force Purchasing and Supply Management Initiatives - Summary of Selected Findings potx
... 36 11 7 45 36 11 7 13 ,13 2 19 ,387 10 ,354 19 ,387 10 ,354 13 ,13 2 11 2 4 31 288 4 31 288 11 2 1, 523 1, 405 3, 715 3, 715 1, 523 1, 405 28 12 1 13 7 28 12 1 13 7 14 6 545 829 14 6 545 829 11 26 61 11 26 61 49 84 206 ... 12 3 67 # # PO PO Cds Cds 20 20 2 ,08 4 2 ,08 4 1, 453 1, 453 17 17 53 53 10 5 10 5 14 7 14 7 27 27 18 18 329 329 16 7 16 7 73 73 96 96 525 52 1, 311 1, 311 6 17 4 17 4 66 66 2 71 2 71 74 74 48 48 1, 137 1, 137 1, 04 3 ... 1, 04 3 1, 04 3 47 47 6 13 3 13 3 29 29 58 58 2 311 311 53 53 69 69
Ngày tải lên: 06/03/2014, 16:20
Summary of 2013 Budget Measures Policy Changes doc
... A . 10 A . 10 A .11 A .11 A .11 A .11 A.4 Taxation Measures for Introduction in 2 01 3 Yield/Cost 2 01 3 Yield/Cost Full Year Maternity Benefit to be taxable for all claimants with effect from July 2 01 3 ... Registration Tax (VRT) +€50m + 10 0m + 10 0m + 18 0m + 18 0m +€25m +€25m +€6m +€22m -€35m -€70m Nil - 10 m Rates of VRT are being increased with effect from January 2 01 3 Details of the revised rates are ... base year ( 200 3) Finance Act 2 01 2 provided that the first 10 0, 000 of qualifying R&D expenditure would benefit from the tax credit without reference to the 200 3 threshold The amount of expenditure...
Ngày tải lên: 07/03/2014, 04:20
Measuring Changes in Service Costs to Meet the Requirements of the 2002 ppt
... Example of Savings Calculations Assume that Base X spent $ 10 0M for 10 0 units of Service A and $ 10 0M for 10 0 units of Service B in the base year, for a total of $ 200 M (Step 1) As a result of a mission ... 200 4 by the RAND Corporation 17 00 Main Street, P.O Box 213 8, Santa Monica, CA 904 07- 213 8 12 00 South Hayes Street, Arlington, VA 22 202 - 505 0 2 01 North Craig Street, Suite 202 , Pittsburgh, PA 15 213 -15 16 ... Data on Future Expenditures Translating Planning Data into Service Cost Estimates v 10 10 11 12 14 16 16 17 17 vi Measuring Changes in Service Costs Step 4: Calculating That Which “Would...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Fluorescence quenching and kinetic studies of conformational changes induced by DNA and cAMP binding to cAMP receptor protein from Escherichia coli ppt
... )1 )1 KSV1 (M ) KSV2 (M ) V (M ) f1 kmaks1 (nm) kmaks2 (nm) 9. 61 10. 08 7.45 5.54 5 .02 1. 69 2.85 0. 00 0 .00 0. 00 0. 55 0. 57 0. 80 0.78 0. 81 3 50 344 345 346 343 338 338 338 3 40 337 0. 84 0. 27 ... Species s1 (ns) CRPW85A CRPW85A(cAMP)2 CRPW85AICAP CRPW85Alac CRPW85Agal 3 .09 2.99 2.54 4.23 3.93 f1 sm (ns) kq1 (M ặs ) x 10 )1 kq2 (M )1 s )1) x 10 )1 kq1 (M )1 s )1) x 10 )1 0. 69 0. 65 0. 59 0. 57 0. 51 0. 58 ... 0. 27 1. 33 1. 00 1. 00 1. 00 1. 00 1. 00 5.76 6.62 6.35 6 .15 5.53 FQRS spectra of CRPW85A with cAMP are represented in Fig The binding of the ligand results in a blue shift of the total...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... IC 50 (lM) 0. 804 ± 0 .15 7 0. 096 ± 0. 057 35.56 39 .19 0 .19 0 0.325 0. 359 0. 457 ± ± ± ± ± ± 1. 58a 15 .57b 0. 078 0 .11 0b 0 .16 7b 0 .18 1b P < 0. 05 previously characterized for human CPT1B [ 20, 22] Figure 1B ... (GAPDH) gene promoter (GAPp), in the pHW 01 0 plasmid [6,32], to produce P50H–pHW 01 0 , P128H–pHW 01 0 , H50P–pHW 01 0 , H128P–pHW 01 0 , PigE17D–pHW 01 0 , and HumanD17E–pHW 01 0 These constructs were linearized in ... E17D Human D17E a P < 0. 05, b Malonyl-CoA (carnitine = mM) IC 50 (lM) Malonyl-CoA (carnitine = Km) IC 50 (lM) 19 7.58 ± 42.45 683 .05 ± 19 5.64 0. 804 ± 0 .15 7 0. 096 ± 0. 057 0. 5 50 ± 0. 0 70 0 .11 7 ± 0. 009 ...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo Y học: The reactivity of a-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite pdf
... buffer (pH 7.4) and allowed to stand for 30 min, prior to addition of 0. 25 mL of the rHO -1 solution ( 10 3 nmol) The final concentrations of rHO -1 and a-hydroxyhaemin were 10 3 and 38 lM, respectively ... ( 200 0) Heme oxygenase -1 in tissue pathology The Yin and Yang Am J Pathol 15 6, 14 85 14 88 Cary, S.P.L & Marletta, M.A ( 20 01 ) The case of CO signaling: why the jury is still out J Clin Invest 10 7, ... form of rat heme oxygenase -1 in complex with heme Acta Crystallogr D54, 10 17 10 19 30 Yasukochi, Y & Masters, B.S.B (19 76) Some properties of a detergent-solubilized NADPH-cytochrome c (cytochrome...
Ngày tải lên: 23/03/2014, 21:20
What Changes Are Being Made to Social Assistance Benefits: A Community Perspective on the Impact of these Changes. pdf
... #14 10 Prescription Drugs $13 , 712 11 Moving and storage costs $3, 800 12 Home repairs for OW families who own their own homes $3,7 90 13 Vocational Training N/A 14 Birth verification $4 ,08 0 15 ... http://www.incomesecurity.org/OntarioBudget2 01 2 .html Doherty, K., Director of Community Services City of Peterborough (June 14 , 2 01 2 ) Report CSSSJSSC12 -00 4 Discretionary Benefit Report Singer, R ( 200 3, April) The impact of poverty ... the health of children and youth Toronto: Campaign 200 0 http://www.campaign 200 0.ca/res/Poverty_healthbackgrounder.pdf Social Services Division, City of Peterborough (September 16 , 2 01 1 ) Beyond...
Ngày tải lên: 24/03/2014, 00:20
Báo cáo khoa học: Transcription factor specificity protein 1 (SP1) and activating protein 2a (AP-2a) regulate expression of human KCTD10 gene by binding to proximal region of promoter pot
... construct P () 609 ⁄ + 30) containing the whole 639 bp sequence FEBS Journal 276 ( 200 9) 11 14 11 24 ª 200 9 Hunan Normal University Journal compilation ª 200 9 FEBS 11 15 SP1 and AP-2a regulate KCTD 10 R Liu ... ()2 41 ⁄ + 30) -F3 P () 203 ⁄ + 30) -F4 P ( ) 10 8 ⁄ + 30) -F5 P ( )13 ⁄ + 30) -F6 P () 609 ⁄ )2 41) -R AP-2a ⁄ chipF AP-2a ⁄ chipR Sp1 ⁄ chipF Sp1 ⁄ chipR AP-2a ⁄ si Sp1 ⁄ si KCTD10FP KCTD10RP Sp1FP Sp1RP AP-2aFP ... AP-2 FEBS Journal 276 ( 200 9) 11 14 11 24 ª 200 9 Hunan Normal University Journal compilation ª 200 9 FEBS 11 19 SP1 and AP-2a regulate KCTD 10 R Liu et al Fig Effects of Sp1 and AP-2a expression level...
Ngày tải lên: 30/03/2014, 02:20
Báo cáo khoa học: Analysis of the contribution of changes in mRNA stability to the changes in steady-state levels of cyclin mRNA in the mammalian cell cycle doc
... NM _00 9828 Cyclin B1 NM _17 23 01 Cyclin C NM_ 01 6 746 Cyclin D1 NM _00 76 31 Cyclin D2 NM _00 9829 Cyclin D3 NM _00 7632 Cyclin E1 NM _00 7633 Cks2 NM _02 5 415 RanBP1 NM_ 01 1 239 RanGTPase S83456 c-myc NM_ 01 0 849 ... in a 30- lL reaction volume containing 50 mm Tris ⁄ HCl pH 8, 200 mm Hepes, 0 .1 mgÆmL )1 BSA, mm MgCl2, 10 0 lm 2-mercaptoethanol, 20 lm dATP, 20 lm dGTP, 20 lm dTTP and 50 lCi [32P]dCTP ( 300 0 CiÆmmol )1) , ... manufacturer’s protocol For RNA half-life measurements, lgÆmL )1 actinomycin D or 20 lgÆmL )1 DRB was added 0, 30, 60, 12 0 and 18 0 before RNA extraction Total RNA ( 10 lgÆsample )1) was separated on a 1. 2% agarose...
Ngày tải lên: 30/03/2014, 20:20
Báo cáo hóa học: " Mutation or loss of Wilms’ tumor gene 1 (WT1) are not major reasons for immune escape in patients with AML receiving WT1 peptide vaccination" ppt
... population 0. 76% [0. 3% -1. 09 %]) Moreover, to analyze the functional activity of WT1 12 6 -13 4 specific T cells raised by vaccination, the reactivity of CD3+CD8+ T cells against WT1 12 6 -13 4 peptide ... Pathol 200 6, 19 : 804 - 814 Sugiyama H: Cancer immunotherapy targeting WT1 protein Int J Hematol 200 2, 76 :12 7 -13 2 Oka Y, Tsuboi A, Oji Y, Kawase I, Sugiyama H: WT1 peptide vaccine for the treatment of ... gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias Leukemia 19 95, 9 : 10 60 - 10 67 Miwa H, Beran M, Saunders GF: Expression of the Wilms’ tumor gene (WT1) in...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo sinh học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L" pot
... 10 00 12 00 14 00 16 00 18 00 200 0 m/z E 703 .08 B 10 0 702 .35 Relative signal intensity EC146*ISMDYK 80 60 40 20 200 400 600 800 10 00 12 00 m/z F C E-C146*-I-S-M-D-Y-K Figure of Analysis L1-cysteine ... http://www.virologyj.com/content/4 /1/ 1 10 A Sequence m/z 1+ 2+ 14 03 . 902 9 EC *14 6ISMDYK SEVPLDIC*225TSICK 18 80 .19 87 SEVPLDICTSIC*229K 18 80 .19 87 702 .4 515 9 40. 5994 9 40. 5994 9 41. 91 D 10 0 10 0 60 SEVPLDIC225*TSICK 20 10 15 20 25 30 ... 1. 05 .E +05 1. 64.E +05 8. 60. E +04 NT 1. 62.E +05 2.82.E +05 9. 60. E +04 8. 50. E +04 3. 30. E +05 1. 62.E +05 10 0 59.3 92.4 48 .1 91. 4 15 9 54.6 50. 2 18 7 91. 4 17 .5 1. 40 3.37 2 .04 3.86 4.46 5.59 2.47 4 .03 4.43 WT C 102 A...
Ngày tải lên: 18/06/2014, 18:20