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summary of functional characterization studies in sod2 and sod2 deficient mice 31

Expression dynamics of the hepatic mitochondrial proteome of the sod2+  mouse in response to troglitazone administration

Expression dynamics of the hepatic mitochondrial proteome of the sod2+ mouse in response to troglitazone administration

Tổng hợp

... understanding on the association of risk factors in the pathogenesis of idiosyncratic DILI 30 Table Summary of functional characterization studies in Sod2- /- and Sod2+ /deficient mice Genotype Sod2- /- ... evidence linking DILI with mitochondrial dysfunction 16 Table Summary of functional characterization studies in Sod2- /- and Sod2+ /- deficient mice 31 Table Advantages and disadvantages ... the minor groove of PPRE consensus sequence interacts with the DNA-binding domains of PPARγ and RXRα and shields the highly polar side chains of the interacting residues (Asn 160 from PPARγ, and...
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Tài liệu Marketing Research Methods in SAS - Experimental Design, Choice, Conjoint, and Graphical Techniques docx

Tài liệu Marketing Research Methods in SAS - Experimental Design, Choice, Conjoint, and Graphical Techniques docx

Tiếp thị - Bán hàng

... 1.∗ The rows of A are coordinates in a two-dimensional plot for the row points in Y, and the columns of B are coordinates in the same two-dimensional plot for the column points in Y In this artificial ... Green and Wind (1975) for early introductions to conjoint analysis and Green and Srinivasan (1990) for a recent review article Conjoint analysis grew out of the area of conjoint measurement in mathematical ... country -of- origin points as lines drawn from the 0,0 point and extending off the graph, you can see that the “Married with kids” point is closest to the American car line and the “Single” point is...
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Báo cáo khoa học: Systems biology: experimental design Clemens Kreutz and Jens Timmer docx

Báo cáo khoa học: Systems biology: experimental design Clemens Kreutz and Jens Timmer docx

Báo cáo khoa học

... allocation of the experimental material and a random order in which the individual runs of the experiment are performed Randomization minimizes that the risk of unintended confounding because ... only s linear combinations Ap of the parameters could be of interest Here, A denotes an s ã np matrix Often, only the kinetic parameters p are of interest in contrast to the parameters k of the ... within a certain experimental condition of interest In an extreme case, for all samples within a group of replicates, one level of a confounding variable would be realized Over-representation of...
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Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships pot

Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships pot

Kế toán - Kiểm toán

... model in equation so that it is in terms of a quantity that we can estimate Specifically, we redefine the model in equation to be defined in terms of d(xil) instead of xil As illustrated in the ... of the form of its component functions, as well as for the inclusion of additional sources of bias The dye functions are defined as being monotone, and this could be explicitly incorporated into ... functions of the model of equation in terms of basis matrices By combining these basis matrices with the information in the model matrix Z, we can write the eCADS model as a typical regression model in...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Design and Experimental Evaluation of a Vehicular Network Based on NEMO and MANET" pdf

Hóa học - Dầu khí

... maintaining MR1 (and thus MNN1) moving in a 65 meters radius around the position of MR2, and reporting the achievable throughputs None of the MRs have gone out of the access points’ coverage and ... the routing scheme proposed in Section 4.3.1 In this way, OLSR routing entries are maintained in one of the multiple routing tables of the kernel The NEMO daemon already handles policy routing when ... Giaretta, and K Kuladinithi, “Flow Bindings in Mobile IPv6 and Nemo Basic Support,” IETF, Work in progress, draft-ietf-mext-flowbinding-04, November 2009 EURASIP Journal on Advances in Signal Processing...
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Báo cáo y học:

Báo cáo y học: "Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships" pptx

Báo cáo khoa học

... model in equation so that it is in terms of a quantity that we can estimate Specifically, we redefine the model in equation to be defined in terms of d(xil) instead of xil As illustrated in the ... of the form of its component functions, as well as for the inclusion of additional sources of bias The dye functions are defined as being monotone, and this could be explicitly incorporated into ... functions of the model of equation in terms of basis matrices By combining these basis matrices with the information in the model matrix Z, we can write the eCADS model as a typical regression model in...
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Computer aided drug design of neuraminidase inhibitors and MCL 1 specific drugs

Computer aided drug design of neuraminidase inhibitors and MCL 1 specific drugs

Kỹ thuật - Công nghệ

... dataset of active and inactive compounds, calculating descriptors of the compounds present in dataset, splitting dataset into modeling and validation set, creating QSAR model using modeling set and ... Docking Docking program aims to predict the orientation and conformation of the ligand within the binding site of a receptor This is achieved by sampling the conformational space of ligand and binding ... flexible side chain with an amino group can be pan neuraminidase inhibitors Low SD observed for of ZN43, ZN88, ZN35 and ZN46 indicates less deviation in in binding against mutant strains as well as...
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Design, analysis, and experimental verification of continuous media retrieval and caching strategies for network based multimedia services

Design, analysis, and experimental verification of continuous media retrieval and caching strategies for network based multimedia services

Thạc sĩ - Cao học

... caching) used in the memory caching In fact, the shortage of bandwidths in disk caching also may result in the switching operation Moreover, in disk caching, the implementation of the method in ... origin to clients Caching concerns the use of the cache to avoid delays and/ or overheads in accessing the origin There are two typical caching - memory caching and disk caching In memory caching, ... cache and origin in the caching relation Hence, in the memory caching, the main memory is the cache and the disk is the origin In the disk caching, the disk in cache server is the cache and the...
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Knowledge discovery in biomedical research and drug design the development and application of biological databases

Knowledge discovery in biomedical research and drug design the development and application of biological databases

Cao đẳng - Đại học

... for obtaining relevant information The information of particular interest includes the functional aspects of ADR targets, mode of interaction of a target with binding drugs and ligands, as well ... application of data mining in the knowledge discovery in various areas of biomedical research The introduction of data mining in biomedical research in turn enables the development and application of ... academic and company scientists And because of the efforts of these scientists and funding agencies such as NIH in USA and EMBL in Europe, Bioinformatics became more and more prominent and diverse...
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Design, analysis and experimental verification of tubular spaceframe chassis for FSAE application

Design, analysis and experimental verification of tubular spaceframe chassis for FSAE application

Cao đẳng - Đại học

... Loading 0.030 Unloading 0.040 0.050 Angular Deflection (deg) Linear (Loading) 0.060 0.070 0.080 0.090 Linear (Unloading) Graph 94-Structural torsional stiffness “Stressed Skin” frame (round 3) 312 ... Displacement (m) Loading Unloading Graph 100-Structural bending stiffness of bare frame (round 3) 318 5) Simply Supported Bending Test on “Spaceframe” Frame Structural Bending Stiffness of Spaceframe ... Loading Unloading Graph 101-Structural bending stiffness of “Spaceframe” frame (round 1) 319 Structural Bending Stiffness of Spaceframe Frame (SSBT 2) 350.00 300.00 y = 3369625.17x + 0.08 (Loading)...
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Design, analysis and experimental verification of tubular spaceframe chassis for FSAE application 1

Design, analysis and experimental verification of tubular spaceframe chassis for FSAE application 1

Cao đẳng - Đại học

... 185-Investigation of driver ergonomics requirement of chassis 27 Weight of Chassis (kg) 5) Chassis 28 Weight of Chassis vs Cross Section Variation 32.20 32.10 32.00 31. 90 31. 80 31. 70 31. 60 31. 50 31. 40 31. 30 31. 20 ... Figure 129-Investigation of auxiliary requirement of chassis 222 Figure 130-Investigation of rule requirement (B3.9) of chassis Figure 131- Investigation of driver ergonomics requirement of chassis ... 32.00 Weight of Chassis (kg) 31. 80 31. 60 31. 40 31. 20 31. 00 30.80 30.60 30.40 Brace Variation Chart 45-Weight of chassis 20 with respect to variation of orientation of brace 244 TS of Chassis (Nm/deg)...
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SAP2000®  Linear and Nonlinear  Static and Dynamic  Analysis and Design  of  Three-Dimensional Structures

SAP2000® Linear and Nonlinear Static and Dynamic Analysis and Design of Three-Dimensional Structures

Kiến trúc - Xây dựng

... (psf) and a Live Load = 100 psf The Interface The top menu line contains all of the commands and options available to SAP2000, including Define, Draw, Select, Assign, Analyze, Display and Design ... two joints marking the left ends of the two bottom chords The lower left-hand corner of the interface should indicate “2 Points selected” E Click on the Assign menu > Joint > Restraints command ... contain the commands that will be needed most often when using SAP2000, and many of the most frequently used commands are accessible as a single click button in the screen regions surrounding...
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SAP2000 Integrated Finite Elements Analysis and Design of Structures

SAP2000 Integrated Finite Elements Analysis and Design of Structures

Kiến trúc - Xây dựng

... the roof level frame elements and joints in the X-Y Plane @ Z=24 by “windowing.” To this: • Click the Pointer button • Move the pointer above and to the left of the frame elements and joints • ... effect of the Snap to Joints and Grid Points feature Note: Other snap options included in SAP2000 include Snap to Midpoints and Ends, Snap to Element Intersections, Snap to Perpendicular, and Snap ... Pointer button • Move the pointer above and to the left of the support joints • Click and hold the left mouse button • While holding, move the pointer below and to the right of the support joints...
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Báo cáo y học:

Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"

Y học thưởng thức

... two include the substitution of methionine (M) by the amino acids isoleucine (I) or valine (V) in the YMDD motif (C domain) at position rtM204V/I In the majority of cases, these mutations in the ... of lamivudine resistance including determination of ALT values, and especially HBV DNA (viral load) assays are routinely used in the clinic A comparison of these methods is presented in Table ... its role as a ‘baseline’ indicator of HBV infectivity, the measurement of viral load is an indispensable means for monitoring and confirming resistance to lamivudine therapy Indeed, resistance...
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An experimental investigation of heat transfer and fluid flow in a rectangular duct with inclined discrete ribs

An experimental investigation of heat transfer and fluid flow in a rectangular duct with inclined discrete ribs

Môi trường

... discretization of the continuous rib The present investigation was therefore, taken up to determine the optimum width of a gap in the inclined rib to form discrete rib This study will help in determining ... internal size of 2600 mm x 181 mm x 31 mm which consists of entrance section, test section and exit section of lengths of 800 mm, 1200 mm and 600 mm respectively according to the guidelines of ... Experimental studies of augmented heat transfer and friction in asymmetrically heated rectangular ducts with ribs on the heated wall in transverse, inclined, V-continuous and V- discrete pattern Int Journal...
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An experimental investigation of performance and exhaust emission of a diesel engine fuelled with Jatropha biodiesel and its blends

An experimental investigation of performance and exhaust emission of a diesel engine fuelled with Jatropha biodiesel and its blends

Môi trường

... to increase in the specific fuel consumption The increase in fuel consumption requires the increase of volume and duration of fuel injection Since the fuel was injected at fixed injection timing ... remove some unreacted remainder of methanol and catalyst which if not removed can react and damage storing and fuel carrying parts During washing ester present react with water and can form soap Two ... hygroscopic, and as solvents, they may cause corrosion of components, attacking some plastic materials used for seals, hoses, paints and coatings It shows increased dilution and polymerization of engine...
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Theory and design of CNC systems (Học CNC)

Theory and design of CNC systems (Học CNC)

Điện - Điện tử

... screw and spindle but also the rigidity of the machine construc- 1.1 Introduction (a) (b) (c) (d) (e) (f) Fig 1.1 Types of NC machine (a) Robot, (b) Milling Machine (c) Turning machine (d) Machining ... controller are the main functions of the NCK unit An interpreter plays the role of reading a part program, interpreting the ASCII blocks in the part program, and storing interpreted data in internal memory ... to maintainability and training of users To overcome this problem, the standard PLC language (IEC1 131- 3) was established and usage has spread The standard, IEC-1 131- 3, defines five kinds of language;...
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Theory and Design of Electrical and Electronic Circuits

Theory and Design of Electrical and Electronic Circuits

Điện - Điện tử

... siempre being VP the denominated voltage of PINCH-OFF or "strangulation of the channel" defined in the curves of exit of the transistor, whose module agrees numerically with the voltage of cut in the ... relation of transformation or turns magnetic inductance mutual inductance between primary and secondary coupling coefficient inductance of the winding of the primary (secondary open) inductance of ... the winding of the secondary (primary open) inductance of dispersion of the primary L2 (1-k) / n2 R1 R2 R0 C1 C2 inductance of reflected dispersion of the secondary resistance of the copper of...
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Electronics - Theory and Design of Electrical and Electronic Circuits

Electronics - Theory and Design of Electrical and Electronic Circuits

Cơ khí - Chế tạo máy

... siempre being VP the denominated voltage of PINCH-OFF or "strangulation of the channel" defined in the curves of exit of the transistor, whose module agrees numerically with the voltage of cut in the ... relation of transformation or turns magnetic inductance mutual inductance between primary and secondary coupling coefficient inductance of the winding of the primary (secondary open) inductance of ... the winding of the secondary (primary open) inductance of dispersion of the primary L2 (1-k) / n2 R1 R2 R0 C1 C2 inductance of reflected dispersion of the secondary resistance of the copper of...
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