siting interconnection and ppa
Báo cáo y học: " The contrasting roles of PPARδ and PPARg in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue" ppt
Ngày tải lên :
09/08/2014, 23:20
... distinct PPAR subtypes, PPARa, PPARg and PPARδ, with each demonstrating a particular tissue distribution and ligand specificity [3] PPARa is primarily expressed in heart, liver, macrophages and intestines, ... PPARδ in both the mice and the adipocyte cell line (GW610742 EC50 for murine PPARδ is 28 nM compared to 8,900 nM for PPARa and > 10,000 nM for PPARg) [12] and contrasted with a well defined PPARg ... increased in both PPARδ and PPARg agonist-treated cells changes occurring in white adipose tissue from ob/ob mice and 3T3-L1 adipocytes following either PPARδ or PPARg activation, to understand the role...
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Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
Ngày tải lên :
31/10/2012, 17:03
... higher VLDL and LDL levels were observed Results in support of our findings were also obtained by Chen et al [11], who studied PPARδ haplotypes and found that effects on plasma lipids and coronary ... study Since Skogsberg et al and also Chen et al [8, 11] have shown that the PPARδ T+294C SNP is associated with elevated plasma LDL cholesterol and apoB levels in men and we show in this work that ... interaction between PPARδ and apoE Allelic variation in apoE is known to be associated consistently with plasma concentrations of cholesterol, LDL cholesterol and apoB in men and women (reviewed...
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Báo cáo khoa học: Regulated expression by PPARa and unique localization of 17b-hydroxysteroid dehydrogenase type 11 protein in mouse intestine and liver pdf
Ngày tải lên :
07/03/2014, 05:20
... [6] Thus, the activities of the androgen metabolite pair androsterone ⁄ 3,17-androstanediol and abundant expression in steroidogenic tissues such as placenta and gonads have been described [7] ... gene is directly regulated by PPARa and its ligand in the intestine, because of methodologic difficulties, involvement of a tissue-specific factor, in addition to PPARa and RXRa, is likely to be essential ... activation of the peroxisomal genes by a PPARa ligand is only observed in the rodent liver, and not in many other tissues or in human tissues [16] Understanding how PPARa is involved in the transcriptional...
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Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx
Ngày tải lên :
07/03/2014, 12:20
... synthesis (bar graph) and on PPARb-LBD mediated transcriptional activity (bottom row) PPAR activities are shown as the average of triplicates and standard deviation Fig Raf induces PPARb gene expression ... Cox-2 and ERK-dependent increase in the synthesis and release of PGE2 and PGI2 which was mainly due to a strong transcriptional activation of the Cox-2 gene (and to a lesser extent of PGIS and ... and promotes apoptosis [3] The interpretation of these studies is, however, complicated because there is no definitive proof that natural PGI2 is a PPARb agonist and other potential PPARb ligands...
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Báo cáo khóa học: Binding analyses between Human PPARc–LBD and ligands Surface plasmon resonance biosensor assay correlating with circular dichroic spectroscopy determination and molecular docking ppt
Ngày tải lên :
16/03/2014, 16:20
... receptor ligand assay (CARLA) [12] and scintillation proximity assay (SPA) [13], have been used to measure the binding constants for ligandPPARc interactions and in screening of ligands By employing ... of PPARcLBD resulted from the ligand binding In addition, the thermally induced unfolding process of both apo-PPARcLBD and its ligand-bound complexes were also studied using CD spectroscopy, and ... as 20 mM stock solutions for the Biacore and CD experiments Expression and purication of human PPARc ligand binding domain (PPARcLBD) protein pET15b-hPPARcLBD plasmid was kindly provided by J...
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guidelines for facility siting and layout
Ngày tải lên :
02/04/2014, 16:24
... investment, life cycle costs, and risk reduction are inherent in siting and layout decisions Guidelines for Facility Siting and Layout 2.2 Management of Risks Consideration of siting and layout is an important ... criteria Codes and standards must be considered on the federal, state, and local level The federal codes and standards may not be the most stringent Of specific interest are those codes and standards ... Standards, and Local Requirements The site selection and data collection effort will include acquiring copies of codes, standards, and local requirements that pertain to various equipment and...
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báo cáo hóa học: " PPARγ, neuroinflammation, and disease" ppt
Ngày tải lên :
19/06/2014, 22:20
... and metabolic disease Annu Rev Biochem 2001, 70:341-367 Clark RB, Bishop-Bailey D, Estrada-Hernandez T, Hla T, Puddington L, Padula SJ: The nuclear receptor PPAR gamma and immunoregulation: PPAR ... three years with the PPARγ-activating drug pioglitazone This single clinical case thus provides support for a link between PPARγ activation and suppression of neuroinflammation, and suggests avenues ... used a PPARγ-activating drug [16] There are currently two clinical trials in progress testing the efficacy of PPARγ agonists in AD patients Conclusions Pioglitazone and related drugs activate PPARγ,...
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Wind_Farm Technical Regulations Potential Estimation and Siting Assessment Part 1 pdf
Ngày tải lên :
20/06/2014, 05:20
... Technical Regulations, Potential Estimation and Siting Assessment, Edited by Gastón Orlando Suvire p cm ISBN 978-953-307-483-2 free online editions of InTech Books and Journals can be found at www.intechopen.com ... VI Contents Part Siting Assessment of Wind Farms 163 Chapter Advanced Wind Resource Characterization and Stationarity Analysis for Improved Wind Farm Siting 165 Scott Greene and Mark Morrissey ... Reliability and Private Incentives 175 Christopher M.Worley and Daniel T Kaffine Chapter Geotechnical and Geophysical Studies for Wind Farms in Earthquake Prone Areas 191 Ferhat Ozcep, Mehmet Guzel and...
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Wind_Farm Technical Regulations Potential Estimation and Siting Assessment Part 2 potx
Ngày tải lên :
20/06/2014, 05:20
... is demanded to limit the reactive power demand of wind farms after a fault In addition, power limitation is demanded to ensure supply and demand balance if a part of Denmark becomes an island due ... generator, its voltage and current, and many other magnitudes can be found in and around the nacelle (somewhere between 100 and 500 parameter values are sensed in a modern wind turbine), and assist in ... active and reactive powers PWM-converters, therefore, have the capacity to provide for the demand on reactive power and a high frequency switching that make them produce high harmonics and interharmonics...
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Wind_Farm Technical Regulations Potential Estimation and Siting Assessment Part 3 doc
Ngày tải lên :
20/06/2014, 05:20
... René van de Pieterman and Luc Rademakers Energy research Centre of the Netherlands (ECN) The Netherlands Introduction Several European countries have defined targets to install and to operate offshore ... used on the one hand as input for the OMCE-Calculator and on the other hand to monitor certain aspects of the wind farm OMCE-Calculator for the assessment of the expected O&M effort and associated ... offshore and will consist of larger units, typically MW and larger, and the total installed capacity will be 200 to 500 MW, but also wind farms with a capacity in the order of GW are considered New and...
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Wind_Farm Technical Regulations Potential Estimation and Siting Assessment Part 4 potx
Ngày tải lên :
20/06/2014, 05:20
... Potential Estimation and Siting Assessment determinism and creates a partnership between the community and its utility, municipal, financial, educational, special interest and business institutions ... company and other factors defined in the contract Then there is a “shared ownership” arrangement where the community and the wind turbine power company share ownership and split the expenses and ... Regulations, Potential Estimation and Siting Assessment involved either direct community ownership of the wind turbines or land lease rights of ownership of the land upon which the turbines are...
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Wind_Farm Technical Regulations Potential Estimation and Siting Assessment Part 5 pdf
Ngày tải lên :
20/06/2014, 05:20
... follows: Command and control instruments which are legal and regulatory in nature in order to influence behavior Economic instruments which are monetary and supply and demand based in nature and which ... group member and constituency backgrounds, learned behaviors and expectations and assessing their dynamic interactions, abilities and capabilities in order to show them how to attain and instill ... Estimation and Siting Assessment Goals and key project decisions are made up front and must include attention to “process” details such as how will the collaborative team be assembled and managed,...
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Wind_Farm Technical Regulations Potential Estimation and Siting Assessment Part 6 ppt
Ngày tải lên :
20/06/2014, 05:20
... roughness coefficient length and is expressed in metres, and which depends basically on the land type, spacing and height of the roughness factor (water, grass, etc.) and it ranges from 0.0002 up ... Regulations, Potential Estimation and Siting Assessment Land features z0 (mm) Very soft; ice or mud 0.01 Calm open seas 0.20 Chopped high seas 0.50 Snow Surface 3.00 Grassland and green areas 8.00 Pasture ... airports, mowed grassland, etc Open farming areas fitted with no fences and hedgerows and very scattered buildings Only softly rounded hills Farming land dotted with some houses and m tall sheltering...
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ENCYCLOPEDIA OF ENVIRONMENTAL SCIENCE AND ENGINEERING - PPARTICULATE EMISSIONSEMISSION STANDARDS doc
Ngày tải lên :
10/08/2014, 20:20
... experimental and computational techniques, and a considerable expenditure of time and manpower Matters of technique and equipment are covered in source testing manuals as mentioned above and are briefly ... dryness, and the residue is weighed and included with the particulates Corrections to the gas volume depend on sample train operation and on standard conditions for reporting emissions, and these ... number and exact location of traverse sample points, and probes should be premarked for these locations Flow nomographs for sampling nozzles should be made; and all filters, impingers, and other...
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Báo cáo y học: "Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b" ppt
Ngày tải lên :
13/08/2014, 23:20
... 11 Candesartan docked into the VDR ligand binding pocket Candesartan docked into the VDR ligand binding pocket Note: The core structure of the hydrogen-bonded residues is expanded to a 'ball -and- stick' ... arately and superimposed VDR-docked configurations for 1,25-D and Telmisartan, sepVDR-docked configurations for 1,25-D and Telmisartan, separately and superimposed Note: Models depicted as "thick" and ... Theoretical Biology and Medical Modelling 2006, 3:1 Figure docked configurations 1,25-D and TX522 with superimposed X-ray and VDR1,25-D and TX522 with superimposed X-ray and VDR-docked configurations...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 1
Ngày tải lên :
09/09/2015, 10:19
... Ligands and physiological functions of PPARα and PPARδ 1.1.6 Ligands of PPARγ 1.1.7 PPARγ and adipogenesis 10 1.1.8 PPARγ and insulin sensitization 12 1.1.9 PPARs and ... 1997), and down-regulated by tumor necrosis factor-α (TNFα) (Xing et al., 1997) 1.1.5 Ligands and physiological functions of PPARα and PPARδ PPARα is activated by synthetic hypolipidemic fibrates and ... proliferator-activated receptor-α (PPARα) Later on, PPARγ and PPARδ were cloned and characterized to be the isoforms of PPARα (Dreyer et al., 1992; Kliewer et al., 1994) 1.1.2 Structural domains of PPARs As typical...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 2
Ngày tải lên :
09/09/2015, 10:19
... NHE1 by PPARγ 3A2.1 Transcription-defective PPARγ abrogates the effect of PPARγ ligand on NHE1 gene expression From previous sections, we used PPARγ overexpression, PPARγ silencing and PPARγ antagonist ... Down-regulation of NHE1 by PPARγ ligands is PPARγ-dependent The data so far demonstrated that cells that have higher level of PPARγ are more sensitive to PPARγ ligands both at protein and mRNA level As ... PPARγ ligands on NHE1 protein is not drug specific, but is conserved in both the endogenous and synthetic PPARγ ligands.The difference in extent of NHE1 repression by 15d-PGJ2 and synthetic PPARγ...
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