... and pore formation by the T3SS P.-J Matteı et al ¨ des Sciences du Vivant (DSV), CEA P.J.M was supported by a PhD fellowship from the Rhone-Alpes ˆ region and T.I was supported by a PhD fellowship ... minor translocators have also been shown to oligomerize, and this event is essential not only for pore formation, but also for events that take place within the eukaryotic cytoplasm [26,57,58] ... identified that the C-terminal, coiled coil amphipathic domain of YopD, whose structure was solved by NMR by Tengel et al [61], is essential for interacting with LcrV and forming oligomers but does...
... mechanism of dimerization was provided by Byrd et al [25], who showed that dimer formation could occur independently of ligand binding, presumably mediated by direct interactions between the ectodomains ... were analyzed by an immunoprecipitation assay using M2 anti-FLAG affinity resin The resin pellets were washed to remove unbound proteins, separated by reducing SDS ⁄ PAGE, and analyzed by immunoblotting ... shown by York et al [24], who found that a multivalent phosphomannosylated ligand cross-bridged the dimeric receptor to promote optimal internalization This conclusion was reinforced by Byrd et...
... PATENT MEDICINE *** Produced by Bryan Ness and the Online Distributed Proofreading Team HISTORY of the COMSTOCK PATENT MEDICINE BUSINESS and Dr Morse's Indian Root Pills BY Robert B Shaw Associate ... Business The Indian Root Pill business was carried on during most of its existence by two members of the Comstock family —father and son—and because of unusual longevity, this control by two generations ... by the accused or their clerk, opened at No 9, the money taken out and the articles sent as directed, accompanied by bills in the handwriting of Geo Wells Comstock Warrants were then issued by...
... cancer incidence Cancer Causes Control 2004; 15:689–95 37 Polednak AP Lung cancer incidence trends in black and white young adults by gender (United States) Cancer Causes Control 2004; 15: 665–70 ... standard) by geographic area, circa 1980–1982 to 1995–1997 by histologic type: (a) squamous cell carcinoma; (b) small cell carcinoma; (c) adenocarcinoma Figure portrays the trends by histopathologic ... all instances (data available at http://www.iacr.com.fr/devesa2004.htm) Diagnostic techniques may have varied among pathologists, by geographic area and over time, but the patterns and trends...
... Initial studies by Benschop et al [12,25] showed that acetylcholinesterase was selectively inhibited by the C±P– GD stereoisomers by three orders of magnitude more rapidly than by the C±P+ isomers ... hydrolysis of 0.75 mM racemic GD by HuPON1 Stereoisomers of GD were separated as detailed in the Experimental procedures Residual GD concentration at each time point was derived by comparison with a standard ... enzyme-catalyzed hydrolysis of GD was a study by Little et al [18] who reported that an enzyme with a molecular mass of 40 kDa, isolated as a single peak by HPLC from a rat liver homogenate, hydrolyzed...
... transcription and replication by type A, B and C polymerase complexes [20] Furthermore, Weber et al [21] showed that type B but not type A vRNA templates could be used to some extent by the Thogotovirus ... requirements for optimal transcription versus replication of the PB2-like template by measuring the levels of mRNA and vRNA by real-time RT-PCR Results and discussion Analysis of the complete sequences ... by one nt to reach a distance similar to that of the NS seg- http://www.virologyj.com/content/5/1/132 ment, CAT expression was increased two-fold On the contrary, shortening the NS sequence by...
... differentiated by the disadvantages (and advantages) posed by their location across these axes Harm Reduction, MMT and Homelessness Conclusions Harm reduction, including MMT, “driven solely by reducing ... ‘junkie’; ii) negative stereotyping by linking ‘difference’ with undesirable characteristics and fears such as drug users as “dangerous"; iii) ‘othering’ by creating “them” (the labeled person) ... individual drug using and sexual practices, and deal less with the harms associated with the rootcauses of problematic substance use (violence, poverty, racism, historical trauma and so on),...
... of rootcauses of economic progress 19 3.3 ROOT AND ‘PROXIMATE’ CAUSES OF DEVELOPMENT: WHAT ARE THE DIFFERENCES? A major criticism of the rootcauses literature is that its distinction of root ... 2001; and Rodrik et al., 2004) Second, rootcauses are durable, whereas proximate causes vary over time (Glaeser et al., 2004) Third, it is difficult to influence rootcauses through direct policy ... this distinction First, rootcauses are more fundamental than proximate causes In other words, they cause long-run economic progress or decline by influencing the proximate causes (see Acemoglu...
... that (i) (ii) (iii) 12 it leaves a remainder when divided by ; it leaves a remainder when divided by ; it leaves a remainder when divided by The sum of two numbers is 168 The sum of of the smaller ... increased by 10% while its height decreased by 10%, find the area of the new triangle as a percentage of the original one First Round Singapore Mathematical Olympiad for Primary Schools 2004 A box ... division, what is the sum of the first 2004 digits after the decimal point? 2004 ÷ = 286.285714285714 First Round Singapore Mathematical Olympiad for Primary Schools 2004 13 A three digit number 5ab...
... số 188 /2004/ NĐ-CP ngày 16/11 /2004 phương pháp xác định giá đất khung giá loại đất 19 - Thông tư số 114 /2004/ TT-BTC ngày 26/11 /2004 hướng dẫn thực Nghị định số 188 /2004/ NĐ-CP ngày 16/11 /2004 Chính ... định số 197 /2004/ NĐ-CP ngày 03/12 /2004 Chính phủ bồi thường, hỗ trợ, tái định cư Nhà nước thu hồi đất - Thông tư số 116 /2004/ TT-BTC ngày 07/12 /2004 Bộ Tài hướng dẫn thực Nghị định số 197 /2004/ NĐ-CP ... giai đoạn 2004 - 2012 46 2.3.1 Khái quát dự án chuyển đổi mục đích sử dụng đất nông nghiệp 46 2.3.2 Tình hình chuyển đổi mục đích đất nông nghiệp địa bàn huyện giai đoạn 2004 - 2012 ...
... khoán t i Vi t Nam giai ng c a nhân t n 2004- 2012 M c tiêu c mô n ch s giá ch ng tài nh c ng ng n h n dài h n c a nhân t Vi n th ng ch ng khoán n 2004- 2012 Bài nghiên c u g m ph n : Ph n L i ... PH H CHÍ MINH VÕ LÊ MAI NG C A CÁC NHÂN T N CH S GIÁ CH NG KHOÁN T I VI T NAM N 2004 - 2012 Chuyên ngành: Tài Ngân hàng Mã s : 60340201 LU NG D N KHOA H C: NH LAM L u c a v i s ng ... ng 3.2 D li u nghiên c u Trong nghiên c u này, tác gi s d ng d li u hàng tháng t tháng 1 /2004 n tháng 4 /2012 n th nh ng b t n t n n kinh t 2008 (23%) ; S im tv i tình hình l i sách ti n t c a...
... đai Ngày 29/10 /2004 Chính phủ ban hành Nghị định 181 /2004/ NĐ-CP hướng dẫn thi dẫn thi hành Luật đất đai Ngày 01/11 /2004 Bộ trưởng Bộ Tài nguyên Môi trường ban hành Quyết định số 24 /2004/ QĐ-BTNMT ... thị số 05 /2004/ CT-TTg ngày 29/02 /2004 Thủ tướng phủ việc địa phương phải hoàn thành việc cấp giấy chứng nhận quyền sử dụng đất năm 2005 + Quyết định số 24 /2004/ QĐ-BTNMT ngày 01/11 /2004 Bộ Tài ... (từ 46,54% năm 2005 lên 54,53% năm 2012) , tỷ trọng ngành thương mại - dịch vụ tăng (từ 17,6% năm 2005 lên 24,2% năm 2012) Thể qua biểu 3.1 Thu nhập bình quân năm 2012 12,6 triệu đồng/người/năm là,...
... standard protocol by trained interviewers who were retired medical professionals [10] From these measurements, the following variables were created: BMI: weight in kg divided by the square of ... frequently (daily, weekly, monthly, yearly or never) they consumed the food or food groups, followed by a question on the amount consumed in lians (50g/lian) per unit of time A lian is the unit of ... measurement of anthropometrics and other lifestyle factors Protocols for the SWHS were approved by the Institutional Review Boards of all institutes involved in the study Dietary intake and other...
... INAUGURAL ADDRESS BY G.W BUSH IN THE U.S PRESIDENTIAL ELECTION 2004 FROM A PERSPECTIVE OF D.A a study on the inaugural speech made by the incumbent President of the U.S.A in the 2004 presidential ... will defend ourselves and our friends by force of arms when necessary (18) Freedom, by its nature, must be chosen, and defended by citizens, and sustained by the rule of law and the protection ... This part is accompanied by list of References and Appendix Nguyen Thi Huyen Le Vinh Uni AN ANALYSIS OF THE INAUGURAL ADDRESS BY G.W BUSH IN THE U.S PRESIDENTIAL ELECTION 2004 FROM A PERSPECTIVE...