probiotics and regulation of immune responses
THE ROLE OF DMSO IN THE REGULATION OF IMMUNE RESPONSES BY DENDRITIC CELLS
Ngày tải lên :
16/10/2015, 11:59
... just critical APCs for the induction of primary immune responses and the regulation of T cell-mediated immune response (Liu, 2001; Shortman and Liu, 2002; and Banchereau et al., 2001) DCs also ... of the antigenic marker CD68 in humans Figure 1.3 The ontogeny of Monocyte and Macrophage The development and differentiation of monocyte and macrophages from hemapoietic stem cells (Mosser and ... occurrence of adverse immune response in autoimmune diseases, allergy and allograft rejection The antigen presenting cells (APCs) of innate immunity provide the activating signals through regulation of...
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báo cáo hóa học: " The impact of shift work induced chronic circadian disruption on IL-6 and TNF-a immune responses" pot
Ngày tải lên :
20/06/2014, 00:20
... proinflammatory immune responses As possible markers of these changes in the immune system we investigated the proinflammatory cytokines IL-6 and TNF-a and measured the lymphocyte cell count Materials and ... disruption on IL-6 and TNF-a immune responses Journal of Occupational Medicine and Toxicology 2010 5:18 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... shift schedules The mean age of shift workers was 36.4 yrs (SD 9.34) and the mean age of daytime workers 40.1 yrs (SD 7.77; p < 0.001) 86.9% of the shift workers and 75.7% of the day workers were...
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Báo cáo y học: " Chitosan Interferon-c Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses" pps
Ngày tải lên :
08/08/2014, 21:20
... Regulation of antigenspecific CD8+ T cell homeostasis by perforin and interferongamma Science 2000;290:1354–58 49 Lohman BL, Welsh RM Apoptotic regulation of T cells and absence of immune deficiency ... (cDNA) under the regulation of a constitutive promoter as a means of boosting in vivo production of specific cytokines IFN-c and IL-12 have proven effective as prophylactics and adjuncts in therapy ... University of South Florida College of Medicine vivarium All procedures were reviewed and approved by the Committee on Animal Research at the University of South Florida College of Medicine and VA...
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Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx
Ngày tải lên :
09/08/2014, 01:22
... analysis of downregulated genes in functional category of immune response Network-based analysis of downregulated genes in the the functional category of immune response (a) Network and (b) Network ... micrograms of aRNA from each sample (11 SLE patients and six healthy control individuals) and the equivalent quantity of reference aRNA from a mixture of RNA extracted from peripheral blood of 12 ... ng/ml IFN, ng/ml E2, and 500 U/ml IFN or null, and were co-stimulated with TNF and IFN, with IFN and IFN, or with E2 and IFN PBMCs were cultured at a final concentration of 1.5 × 106 cells/ml...
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Báo cáo y học: "A paragon of self-tolerance: CD25+CD4+ regulatory T cells and the control of immune responses" pps
Ngày tải lên :
09/08/2014, 01:23
... with genetic defects of Foxp3 and the experimental depletion of CD25+CD4+ TR cells led several groups to investigate the potential role of Foxp3 in the development and function of TR cells Three ... the inhibition of APCs or pathogenic T cells, by maintenance of the TR cell population and/ or by enhancement of their function (reviewed in [54]) Elucidation of the mechanism of TR cell suppression ... dampen immune responses as required The identification of molecular markers, in particular Foxp3, has permitted the accurate isolation and study of these cells in ways not previously possible and...
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Báo cáo y học: " Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" pptx
Ngày tải lên :
09/08/2014, 13:22
... analysis of downregulated genes in functional category of immune response Network-based analysis of downregulated genes in the the functional category of immune response (a) Network and (b) Network ... micrograms of aRNA from each sample (11 SLE patients and six healthy control individuals) and the equivalent quantity of reference aRNA from a mixture of RNA extracted from peripheral blood of 12 ... ng/ml IFN, ng/ml E2, and 500 U/ml IFN or null, and were co-stimulated with TNF and IFN, with IFN and IFN, or with E2 and IFN PBMCs were cultured at a final concentration of 1.5 × 106 cells/ml...
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Báo cáo y học: " Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses" doc
Ngày tải lên :
11/08/2014, 10:23
... authors thank Professors William Brett and Jim Hughes of the Department of Life sciences and Tista Page of 11 (page number not for citation purposes) Journal of Immune Based Therapies and Vaccines ... Further, only small amounts of phytol and PHIS-01 are required to stimulate immune responses None of these two compounds stimulates reaginic immune responses, nor induces autoimmune lupus-like syndromes ... Vaccine Formulation: Assessment of Safety and Efficacy in the Induction and Protective Immune Responses to Lethal Bacterial infections in Mice J Immune Based Therapies and Vaccines 2006, 4:5 Bendavid...
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Báo cáo khoa học: " Characterisation of immune responses and protective efficacy in mice after immunisation with Rift Valley Fever virus cDNA constructs" pot
Ngày tải lên :
12/08/2014, 04:21
... structural proteins of RVFV The elicited immune responses towards the N, GN, GC and GN/GC proteins after gene-gun immunisation were analysed and the protective abilities of the N and the GN/ GC construct ... protein and truncated variants thereof Western blot reactivity towards the N protein and truncated variants thereof (A) Schematic presentation of the full length and deleted variants of the RVFV ... Ethics Committee of Umeå University, Sweden Evaluation of immune response To evaluate and compare the immune responses after vaccination and infection, eight animals were vaccinated with cDNA...
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Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
Ngày tải lên :
14/02/2014, 19:20
... Scientific Fund of the Ministry of Education, Science and Culture of Japan (G.T.); the Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation ... of miR-221 and miR-222 in PC12 cells, and that this induction is dependent on sustained activation of the ERK1 ⁄ pathway [20] Furthermore, the induction of miR-34a depends on the activation of ... Indeed, several examples of feedback regulation that involve miRNAs have been reported Below, we attempt to summarize our recent understanding of feedback regulation of signal cascades that involve...
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Tài liệu Báo cáo Y học: Characterization and regulation of yeast Ca2+-dependent phosphatidylethanolamine-phospholipase D activity docx
Ngày tải lên :
22/02/2014, 07:20
... pattern and extent of stimulation of the membrane and soluble yeast PtdEtnPLD activity by Ca2+ and their inhibition by other divalent cations is highly comparable The mechanism of action of Ca2+ ... promoter region of INO1 and other genes that are part of the INO1 regulon [45] As regulation of phospholipid biosynthesis and degradation are likely to be coordinated, it was of interest to examine ... both wild-type and spo14D cells Future identification of the PtdEtn-PLD gene and analysis of its promoter region will allow examination of its transcriptional regulation by inositol and the possible...
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Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
Ngày tải lên :
22/02/2014, 07:20
... macrophages and lymphocytes are able to produce a higher amount of anandamide and/ or 2-AG [21,23–26] IgE-dependent stimulation of RBL-2H3 cells also leads to the formation of anandamide and of its ... Purification and quantification of endocannabinoids The extraction, purification and quantification of anandamide, 2-AG and PalEtn from immature and mature dendritic cells requires a set of different ... potent antigen-presenting cells of the immune system They play a central role in the initiation of primary immune response and in the enhancement of secondary immune response [37,38] Immature...
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Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx
Ngày tải lên :
07/03/2014, 03:20
... constituent of the Tic motor complex (see below) The present minireview provides a short description of recent advances in the understanding of the channel-, motor- and regulatory components of the ... plants of the pea ortholog and main Arabidopsis isoform of Tic20, AtTic20-I, similarly exhibit pronounced chloroplast defects, and attic20-I knockouts were albino even in the youngest 1168 parts of ... function (e.g in ligand-gated and voltage-gated K+ channels) [16], and thus could provide an explanation for the observed channel activity of Tic110, as well as for the binding of transit peptides...
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Báo cáo khoa học: Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription ppt
Ngày tải lên :
08/03/2014, 02:20
... numbers represent the intensity of each band normalized to the band in lane The lower numbers represent the intensity of the bands in lanes and normalized to the band in lane In order to map the position ... R2 TATA-box, and also as a repressor of transcription, as a deletion or a mutation of this sequence or addition of TAFII135 antibodies leads to a three- to fivefold up -regulation of transcription ... with high concentrations (50 lM) of polyamide (Fig 1C) Importance of the R2 TATA-box and TBP binding to the R2 promoter We next studied the importance of TBP and the R2 TATA-box in an in vitro...
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Báo cáo khoa học: Characterization and regulation of a bacterial sugar phosphatase of the haloalkanoate dehalogenase ppt
Ngày tải lên :
14/03/2014, 23:20
... number of phosphate containing substrates, and it has a high specificity for nucleotide monophosphates and, in particular, UMP and GMP The structure of NagD has been determined and the occurrence of ... family of NagDlike phosphatases to be characterized at the level of gene regulation Results and Discussion The araL gene in the context of the B subtilis genome and in silico analysis of AraL ... Fig Overproduction and purification of recombinant AraL-His6 (A) Analysis of the soluble (S) and insoluble (P) protein fraction (20 lg of total protein) of induced cultures of E coli Bl21(DE3)...
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Characteristics and Regulation of Exempt Institutions and the Implications of Removing the Exemptions pptx
Ngày tải lên :
15/03/2014, 09:20
... corporation Office of the Comptroller of the Currency Office of Thrift Supervision savings and loans Securities and Exchange Commission Summary of Deposits Department of the Treasury This is a work of ... availability and allocation of credit, the stability of the financial system and the economy, and the safe and sound operations of such institutions To determine the number of certain types of financial ... other hand, accounted for about percent of credit card loans, but they accounted for less than percent of construction and land development loans and almost none of any other type of loan Grandfathered...
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Consultative Document Strengthening Oversight and Regulation of Shadow Banking docx
Ngày tải lên :
16/03/2014, 08:20
... Weighted-average • Outstanding amount of function 23 • Outstanding amount of off-balance sheet exposures by instruments (compared to capital) • Outstanding amount of off-balance sheet exposures ... availability and hence on the real economy by expanding their businesses and facilitating the creation of credit in boom times where risk appetite is high and credit costs and losses are low, and scaling ... availability and hence on the real economy by expanding their businesses and facilitating the creation of credit in boom times where risk appetite is high and credit costs and losses are low, and scaling...
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Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice ppt
Ngày tải lên :
16/03/2014, 18:20
... (C and D) are shown For each series of protection reactions, 10 pg of undigested probe control (P) and a no target control that consists of 400 pg of probe combined with excess yeast RNA and ... rate of transcription of the CB1 gene was decreased in the striata of R6 mice and that this decrease led to the observed decrease in steady-state levels of mature CB1 mRNA Comparison of human and ... the primary cause of HD Examination of the regulation of individual mutant huntingtin-affected genes such as CB1 may increase our understanding of at least one abnormal function of mutant huntingtin...
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Báo cáo khoa học: Function and regulation of ABCA1 – membrane meso-domain organization and reorganization pptx
Ngày tải lên :
22/03/2014, 15:21
... N & Tall AR (2010) Role of HDL, ABCA1, and ABCG1 transporters in cholesterol Function and regulation of ABCA1 100 101 102 103 104 105 106 107 108 109 efflux and immune responses Arterioscler Thromb ... Function and regulation of ABCA1 CDC42, a member of the Rho GTPase family, is reported to interact with ABCA1 and the interaction enhances apoA-I-mediated cholesterol efflux [47] Palmitoylation of ABCA1 ... 3195 Function and regulation of ABCA1 K Nagao et al ABCA1 whereas direct binding of photoactive cholesterol to ABCA1 could not be detected [74]; however, analysis of the functions of ABCA7 raised...
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Báo cáo khoa học: Signalling and regulation of collagen I synthesis by ET-1 and TGF-b1 doc
Ngày tải lên :
23/03/2014, 11:20
... effects of ET-1 on collagen I synthesis and breakdown clearly indicate an important role for ET-1 in the dynamic regulation of ECM and its dysregulation in disease [19] ET-1 and its isoforms ET-2 and ... expression of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) and inducing that of matrix metalloproteinase-2 (MMP-2) [7,16], which in turn degrades MMP-1 cleaved collagen I [17] Regulation of ... involvement of the PC-phospholipases We used D609 to specifically inhibit PC-PLC [46], and neomycin [47–49] and N-butanol [50–52] as specific inhibitors of PLD The inhibition of PC-PLC by D609 (Fig 5B) and...
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