polyunsaturated fatty acid nutrition in infants born at term
Báo cáo khoa học: Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan ppt
Ngày tải lên :
07/03/2014, 12:20
... contain a fused cytochrome b5 as an N-terminal domain and three histidine boxes in the desaturase (C-terminal) domain The third histidine box has the QX2HH instead of the HX2HH motif present in ... front-end desaturases are present in each of these trypanosomatid proteins, including the three highly conserved histidine boxes and the cytochrome b5 N-terminal domain (Fig 1) Interestingly, the ... aforementioned exceptions In a phylogenetic analysis [16], I galbana desaturase was located in a cluster distinct from all other D4 desaturases, indicating that it has evolved in an independent way, but...
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báo cáo khoa học: " Mapping quantitative trait loci (QTLs) for fatty acid composition in an interspecific cross of oil palm" ppt
Ngày tải lên :
12/08/2014, 03:21
... content is positively correlated with the unsaturated fatty acids C18:1 and C18:2 The results also indicate that the saturated fatty acids C14:0 and C16:0 are negatively correlated with IV, C18:1 and ... abundant unsaturated fatty acid while C16:0 is the most abundant saturated fatty acid in palm oil, it is only logical to assume that the same genomic region is influencing these traits in oil palm ... would greatly facilitate hybrid-breeding programmes as well as speed up the development of planting materials with an oil composition high in unsaturated fatty acids (especially oleic fatty acid) ...
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Báo cáo y học: " A predictive model for respiratory syncytial virus (RSV) hospitalisation of premature infants born at 33–35 weeks of gestational age, based on data from the Spanish FLIP study" pdf
Ngày tải lên :
12/08/2014, 14:20
... of the risk factors linked to respiratory syncytial virus infection requiring hospitalisation in premature infants born at a gestational age of 33–35 weeks in Spain Pediatr Infect Dis J 2004, 23(9):815-820 ... hospitalisation of premature infants born ≤ 35 wGA Questionnaires were sent to all parents of infants discharged from primary neonatal care to determine the event of rehospitalisation for acute respiratory ... factors that predispose infants to developing severe RSV leading to hospitalisation [19] Subsequent prospective studies in Spain [9], Canada [7], and Germany [20] examined those risk factors in infants...
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Báo cáo y học: "Disruption of cell wall fatty acid biosynthesis in Mycobacterium tuberculosis using a graph theoretic approach" pptx
Ngày tải lên :
13/08/2014, 16:20
... demonstrated that the protein that most influences the pathway is FAS (Fatty Acid Synthase) As demonstrated in Figure 2, the nearness indices of the proteins involved in the digraph can be determined ... the interaction properties in protein-protein complexes; for example, identifying the domains involved in binding or analyzing the 3D structure Comparison of domain-domain interactions and interfaces ... proteins involved in the fatty acid biosynthesis pathway Ranking proteins by the topological properties of the human protein-protein interaction net-work is one strategy for drug-target identification...
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Maternal polyunsaturated fatty acid status and offspring allergic disease up to the age of 18 months
Ngày tải lên :
30/09/2015, 10:11
... participants in this study VIII LIST OF ABBREVIATIONS SFA Saturated fatty acid MUFA Monounsaturated fatty acid PUF Polyunsaturated fatty acid LA Linoleic acid EPA Eicosapentaenoic acid DHA Docosahexaenoic ... leading to postnatal airway inflammation 228 229 1.3 Polyunsaturated fatty acid (PUFA) 230 1.3.1 Definition and nomenclature 231 There are three kinds of fatty acid: saturated (SFA), monounsaturated ... that maternal polyunsaturated fatty acid (PUFA) status during pregnancy may influence early childhood allergic diseases, although findings are inconsistent We examined the relation between maternal...
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Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas
Ngày tải lên :
05/09/2013, 10:17
... We define the fatty acids with > 5% content as dominant fatty acids and Fig shows the dominant fatty acids in the leaves and stems of Z japonica in each sampling site The term “other” in the ... Sampling conditions and cooperating institutions during sampling Table - Sampling conditions and cooperating institutions during sampling Site Z japonica Code Sampling Month-Year Water Water ... content in the Fig.4 Dominant fatty acid content in the roots the Fig - Dominant fatty acid content in and stems at each sampling site．sampling and rhizomesand rhizomes site． each leaves and stems at...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
Ngày tải lên :
14/02/2014, 22:20
... other unsaturated (linoleic acid, 18:2 cis) or saturated (palmitate) fatty acids were used instead of HepG2 cells, oleate, and stearate, respectively (results not shown) Stearate treatment induces ... shown that different forms of fatty acids exert remarkably different effects Exposure of a variety of cell types, including hepatocytes, to long-chain saturated fatty acids (SFAs) led to increased ... internalization, FFAs are converted to fatty acyl-CoA, a reaction catalyzed by ACS Fatty acyl-CoAs are activated forms of fatty acids that can be either oxidized in mitochondria or utilized in...
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Tài liệu THE ROLES OF AMINO ACID CHELATES IN ANIMAL NUTRITION pdf
Ngày tải lên :
15/02/2014, 16:20
... ortho-phosphatetransglucosidase Adenylate kinase Creatin kinase Arginine kinase 1,3-Diphosphoglycerate -> ADP-Transphosphatase Pyruvate kinase Hexokinase 6-Phosphofructokinase Galactokinase Phosphoglucokinase ... and highly encouraging At that point in time these amino acids were called "metal proteinates" instead of chelates Concurrently, with the development of the amino acid chelates, a second school ... AMINO ACID CHELATES IN ANIMAL NUTRITION THE ROLES OF AMINO ACID CHELATES IN ANIMAL NUTRITION Edited by H DeWayne Ashmead Albion Laboratories, Inc Clearfield, Utah Reprint Edition NOYES PUBUCATIONS...
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Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt
Ngày tải lên :
19/02/2014, 08:20
... a catalytic base in the decarboxylation reaction, and (c) H333 stabilizes the negative charge on C163 in the native enzyme, whereas in the intermediate fatty acyl complex it participates in the ... weak, binding of ACP to the docking site followed by a conformational change in ACP proposed to inject the acyl chain into the substrate-binding pocket [32] If a similar mechanism is involved in ... manuscript was in preparation, White et al [33], in a review covering type II fatty acid synthesis, postulated that His298 is a general base activating a water molecule for nucleophilic attack on...
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Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf
Ngày tải lên :
19/02/2014, 16:20
... maintained in quiescent mode by incubation for 24 h in serum-free medium containing 0.2% (w/v) fatty acid- free BSA Then, SMC were incubated or not incubated (control) with PUFA complexed with fatty ... proliferation and retinoblastoma protein (Rb) phosphorylation after supplementation with n-3 and n-6 polyunsaturated fatty acids (PUFAs) (A,B) Effects of n-3 and n-6 PUFAs in cells stimulated by interleukin-b ... the incorporation of BrdU into SMC was strongly stimulated by incubation in medium containing 10% (v/v) fetal bovine serum Although the incorporation of AA alone did not affect BrdU incorporation,...
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Báo cáo khoa học: Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling docx
Ngày tải lên :
07/03/2014, 05:20
... incorporation as in YB526, indicating that Fat2p is not responsible for the remaining capacity to channel exogenous fatty acids into lipids Control strains carrying deletions in only FAT1 or FAT2, or in both ... (hatched), 18:1 (light gray) (B) Time-course of intracellular free fatty acid accumulation Intracellular free fatty acids accumulated by cells of YB526 were determined at the time points indicated ... of accumulated free fatty acids Whereas convincing data had been presented showing that Fat1p is impor- Fatty acid secretion in mutants of yeast tant for fatty acid import in S cerevisiae [27],...
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Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio) pptx
Ngày tải lên :
07/03/2014, 06:20
... according to the tissue from which they were initially isolated, e.g livertype fatty acid- binding protein (L-FABP), brain-type fatty acid- binding protein (B-FABP), intestinal-type fatty acid- binding ... lipid-binding protein, intestinal 15 kDa protein, ileal bile acid- binding protein and gastrotropin, reflecting the speculations of authors on its intracellular function(s) In vitro binding assays ... (1972) A binding protein for fatty acids in cytosol of intestinal mucosa, liver, myocardium, and other tissues Science 177, 56–58 Haunerland NH & Spener F (2004) Fatty acid- binding proteins – insights...
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Báo cáo Y học: Restoring enzyme activity in nonfunctional low erucic acid Brassica napus fatty acid elongase 1 by a single amino acid substitution pdf
Ngày tải lên :
08/03/2014, 09:20
... primers PCR incubations were run 30 sec at 95 °C (denaturation) followed by 16 cycles of 30 sec at 95 °C, at 55 °C, 15 at 68 °C and terminated by 15 at 68 °C Following temperature cycling, the product ... acid serine at position 282 in the FAE1 protein sequence to determine if this apparent mutation from serine to phenylalanine led to the LEA B napus phenotype We introduced a point mutation into ... serine amino acid residue at that position, in the catalytically inactive protein from LEA cv Westar serine 282 is substituted by phenylalanine (Fig 1) Fig Alignment and comparison of amino-acid...
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Báo cáo khoa học: Differential tissue-specific distribution of transcripts for the duplicated fatty acid-binding protein 10 (fabp10) genes in embryos, larvae and adult zebrafish (Danio rerio) docx
Ngày tải lên :
16/03/2014, 00:20
... partial amino acid sequencing of an amphibian liver fatty acid binding protein Biochem Cell Biol 74, 109–115 ´ ´ ´ Cordoba OL, Sanchez EI & Santome JA (1999) The main fatty acid- binding protein in the ... liver, intestine, heart muscle and adipose tissue FABPs Mol Cell Biochem 239, 25–33 14 Veerkamp JH & van Moerkerk HTB (1993) Fatty acidbinding protein and its relation to fatty acid oxidation ... liver-type fatty acid binding protein in adult zebrafish (Danio rerio) Biochim Biophys Acta 1492, 227–232 ´ Di Pietro SM, Veerkamp JH & Santome JA (1999) Isolation, amino acid sequencing and binding...
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Báo cáo khoa học: Fatty acid composition of chylomicron remnant-like particles influences their uptake and induction of lipid accumulation in macrophages pot
Ngày tải lên :
16/03/2014, 12:20
... type of fatty acid predominating in the oil, but also contained a complex mixture of other fatty acids, as occurs in vivo As might be expected, the fatty acid composition of CRLPs containing TG ... that the type of fat in the diet in uences the development of atherosclerosis, with consumption of polyunsaturated (PUFA) or monounsaturated (MUFA), as compared with saturated (SFA), fatty acids ... respectively, into the particles were incubated with THP-1 macrophages, and the concentrations of cholesterol and TG accumulated were determined In addition, the effects of varying fatty acid composition...
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Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle pdf
Ngày tải lên :
17/03/2014, 08:20
... driven by fluctuations in the national twinning rate (i.e # twin births / # births) and not by fluctuations in the birth rate Interestingly, the yearly deviation in the twinning rate is significantly ... business cycle indicator in our birth-year window or in larger windows The same applies to the national rate of twin births (i.e # twin births / population size) Fluctuations in the latter rate are ... mortality rate later in life,19 while the business cycle effect itself is insensitive to the inclusion of these indicators Apparently, these indicators are insufficiently informative as determinants...
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Báo cáo khoa học: Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans pot
Ngày tải lên :
22/03/2014, 16:21
... levels during in ammation The pro -in ammatory cytokines interleukin-1b, interleukin-6 and tumor necrosis factor-a are able to induce CYP4Fs, whereas the anti -in ammatory cytokine interleukin-10 suppresses ... mechanisms involved in C26:0 metabolism Very long-chain fatty acids are predominantly derived from long-chain fatty acids via chain-elongation and degraded via b-oxidation in the peroxisome Several ... al Fatty acid oxidation disorders Fig Schematic diagram depicting the different mechanisms by which fatty acids can be oxidized (see text) General aspects of fatty acid oxidation Beta-oxidation...
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Báo cáo khoa học: The role of cytochrome P450 monooxygenases in microbial fatty acid metabolism pdf
Ngày tải lên :
22/03/2014, 16:21
... similarity and binding affinity experiments with fatty acids, it was suggested that CYP110 is related to fatty acid x-oxidation of saturated and (poly)unsaturated fatty acids and subsequent formation of ... and ⁄ or fatty acids Fatty acid degradation – omega oxidation Although cytochrome P450s not intervene in the degradation of fatty acids in the b-oxidation cycle itself, they take part in the steps ... acids Not only are hydroxylated fatty acids intermediates in alkane and fatty acid metabolization, they can also be useful components as such a-Hydroxylated long-chain fatty acids, for example, are...
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Báo cáo khoa học: Suppression of nuclear factor-jB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles pot
Ngày tải lên :
23/03/2014, 04:20
... established that consumption of saturated fats (SFA) is associated with increased risk of atherosclerosis development, whereas intake of monounsaturated fats (MUFA) and polyunsaturated fats (PUFA) ... 18-carbon fatty acids Ann Nutr Metab 51, 155–162 45 Lee JY, Sohn KH, Rhee SH & Hwang D (2001) Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated ... formation is in uenced by dietary fatty acids during their transport from the gut to the liver in CMR in the postprandial phase In this study, we investigated the effects of CMR on NF-jB activation...
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Báo cáo khoa học: Metabolic pathway that produces essential fatty acids from polymethylene-interrupted polyunsaturated fatty acids in animal cells pot
Ngày tải lên :
23/03/2014, 09:20
... radiolabeled fatty acid was formed The labeled fatty acid migrated at a position corresponding to linoleic acid on AgTLC, indicating that [2-14C]malonyl-CoA was incorporated into 16:2 D-7,10 to form linoleic ... biosynthesis of polyunsaturated fatty acids in K562 cells Biochem J 291, 841–845 26 Dhopeshwarkar GA (1976) Biosynthesis of polyunsaturated fatty acids in the developing brain II Metabolic transformations ... 16:2 D-7,10 into linoleic acid (18:2 D-9,12) by the fatty acid chain-elongation system in rat liver microsomes c-linolenic acid (18:3 D-6,9,12), 16:2 D-7,10 or linoleic acid was incubated with...
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