pharmacological and chemopreventive studies of chrysanthemum
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... characterization of numerous complexes of the human HPRT and several bacterial and protozoan HPRTs have been undertaken [13–17] The structure of human HPRT can be divided into two domains: a core domain and ... domain is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9 and an a-helix from the C-terminus (Fig 1A) The two subunits ... the base of bound GMP is stacked between Val143 and Phe194 N1, N2 and O6 of the nucleotide form hydrogen bonds to main chain atoms, whereas the side chain of Lys173 interacts with both O6 and N7...
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Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... A-chain and B-chain of nPS, and in the case of His37, the v1 torsion angle changes from 63.34° to )67.80° and )52.11° for the A-chain and B-chain of nPS, respectively The imidazole ring of His34 ... we report the results of the structural studies of the pantoate-bound form of the N-terminal domain of E coli PS (nPS) The structure and substrate-binding interactions of E coli nPS have been ... specific residues of nPS as a function of substrate(s) The resonances of free nPS are shown in red, those of nPS bound to D-pantoate are shown in blue, and those of nPS bound to D-pantoate and ATP are...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
... possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL [21,34] support ... of hydrogen, modification of bonds, potentials of forcefield, and fixation of heavy atom, backbone, and Ca, were performed for molecular mechanics calculations and then the energy minimization of ... of primary-sequence similarity with pancreatic lipase, and the conservation of most of the disulfide bonds between LPL and PL suggests a similar tertiary structure For the two dimeric models of...
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Báo cáo khoa học: Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability potx
... NMR studies [16,19,20,23] The energy of folding these various forms and the energetic cost of converting one form to another is of fundamental importance for understanding telomere biology and ... practical details of UV melting studies of G-quadruplexes, with an thorough discussion of common problems and pitfalls [32] The use of fluorescence to monitor the thermal denaturation of quadruplex-forming ... signal for the determination of the fraction of folded or unfolded DNA strand, allowing for the calculation of the equilibrium distribution of conformational forms Standard methods using UV absorbance...
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Báo cáo khoa học: Fluorescence quenching and kinetic studies of conformational changes induced by DNA and cAMP binding to cAMP receptor protein from Escherichia coli ppt
... calculated from the ratio of the rate constants kon and koff as follows: Ka ẳ kon koff 2ị Association constants (Ka) of CRP with the three investigated sequences of DNA lacF, galF and ICAPF are summarized ... nuclear magnetic resonance study of the cyclic AMP receptor protein (CRP): assignments of the NH protons of histidine and tryptophan residues and the effect of binding of cAMP to CRP Biochem J 107, ... DNA and cAMP i.e free CRP, CRP(cAMP)2 and CRP(cAMP)4 In the presence of % 100 lm cAMP, the protein becomes activated by the formation of a CRP(cAMP)2 complex and it is then able to recognize and...
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Báo cáo khoa học: Comparative biochemical and functional studies of family I soluble inorganic pyrophosphatases from photosynthetic bacteria potx
... Rao and Dr J Josse for critical review of the manuscript, and Professor W Loffelhardt (University of Vienna, Austria) for ¨ his assistance in N-terminal protein sequencing and some MALDI-TOF MS ... molecular mass of 19 216 Da and a pI of 4.69, in good agreement with MALDI-TOF MS (Fig 1A) and chromatofocusing data, respectively The other three N-terminal sequences determined in this work, of Anabaena ... UÆmg)1 protein and recovery levels of 20– 30% In all cases, the analysis by SDS ⁄ PAGE and native PAGE of purified preparations showed only one protein band of 20–22 kDa (Figs and 2; supplementary...
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Báo cáo Y học: Unfolding and refolding studies of frutalin, a tetrameric D-galactose binding lectin doc
... turns) and 16% of other contributions for both the native and refolded forms, with a rmsd of 1% The deconvolution of Mfrutalin showed 13% of a helix and 12% of b components (antiparallel and parallel ... where N and U represent the native and reversibly unfolded forms of the frutalin and kN and kU, the equilibrium constants of the unfolding transitions from the N to the U state The fraction of unfolded ... Nfrutalin and Rfrutalin-Ch were deconvoluted by convex constraint analysis [19,20] as described in Materials and methods, and showed 86% of beta components (antiparallel and parallel b sheet, and b...
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Báo cáo khoa học: Antimicrobial and conformational studies of the active and inactive analogues of the protegrin-1 peptide docx
... In IB-367 and BM-1, the presence of strong daN(i,i + 1) and weak (or absence of) dMN(i,i + 1) and dbN(i,i + 1) NOE connectivities in the Gly3–Arg8 and Cys14– Gly16 regions of IB-367 and in the ... Arg1 and Arg17, and in the turn in the presence of Arg8 and Arg10 (see Figs and 4) Our conformational studies showed that BM-1 formed a twisted b-sheet structure, similar to that of native PG-1 and ... activity of the peptides A better understanding of the mode of action of these peptides is crucial for the development of a new generation of antibiotics It is known that, in the absence of both...
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Báo cáo Y học: Engineering and mechanistic studies of the Arabidopsis FAE1 b-ketoacyl-CoA synthase, FAE1 KCS pot
... Lane and 9, respectively, P and S fractions of 0.5% Triton X-100 plus 0.32 M NaCl treatment of thrombin digested microsomes Lane 10 and 11, respectively, P and S fractions of M NaCl treatment of ... respectively Lanes and 5, respectively, P and S fractions of untreated thrombin digested microsomes Lanes and 7, respectively, P and S fractions of 0.5% Triton X-100 treatment of thrombin digested ... mutational studies of chalcone synthase have demonstrated that decarboxylation of malonyl-CoA is independent of acylation of the active site cysteine [24] In these studies, substitution of the active-site...
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Báo cáo khoa học: Crystal structure determination and inhibition studies of a novel xylanase and a-amylase inhibitor protein (XAIP) from Scadoxus multiflorus pot
... concentration of XAIP (b) and with lM concentration of chitinase enzyme (c) for h, and (B) in the absence of any protein (a), with 100 lM concentration of XAIP (b) and with 100 lM concentration of chitinase ... internal space of the TIM barrel considerably Of the three observed cis peptides, two (Gly33–Phe34 and Trp253–Asp254) are found at the ends of b-strands b2 and b8, respectively These are part of the ... interactions between residues of a7 and those of GH10 because of steric hindrance On the other hand, it has been shown by solution studies that XAIP inhibits the activity of a-amylase in a : 1.2 molar...
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Báo cáo khoa học: Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1 pptx
... mechanism of the AspB-catalyzed reaction and pKa values of potential acid and base catalysts by pH-rate studies From the ascending limb of the pH-rate prole of AspB, a residue with a pKa of 7.1 ... obtained from grafit software Kinetics of reversible inhibition of AspB, T141A and H188A by 3-nitropropionate and D-malate The reversible inhibition of AspB and the T141A and H188A mutants was ... pH-rate and inhibition studies to further illuminate the mechanistic role of certain residues The results obtained in these studies are interpreted and related to the mechanisms of AspA and other...
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Báo cáo toán học: " Structural, optical and magnetic studies of manganese-doped zinc oxide hierarchical microspheres by self-assembly of nanoparticles" docx
... reports as well [31] The XPS data of Zn2p and Mn2p further provide evidences for the incorporation of Mn2+ ions into ZnO To obtain a better understanding of the formation of Mn-doped ZnO HMSs, a probable ... coordination route of EG which directs the formation of Mn-doped ZnO HMSs in view of morphology transformation A lot of EG molecules are adsorbed on the (001) surface of the ZnO crystals and block the ... spectra The origin of the peaks at 425 and 475 nm could be ascribed due to the transition occurring from Zn interstitials to the valence band, and the peak of 425 nm may be the result of the singly...
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Báo cáo toán học: "Antioxidant, antimicrobial, and theoretical studies of the thiosemicarbazone derivative Schiff base 2-(2-imino-1-methylimidazolidin-4-ylidene)hydrazinecarbothioamide (IMHC)" potx
... presence of two absorption bands at 1273.7 and 3421 cm−1 belonging to the C=S and NH groups, respectively, and by absence of SH Density functional theory (DFT) studies DFT calculations of the IMHC ... nature of functional group of IMHC The appearance of a broad strong band in the IR spectra of IMHC in 3421 cm–1 is assigned to N–H stretching vibrations of the primary amine group The spectrum of ... synthesis of some bioactive compounds such as ß-lactams [16–18], and employed as ligands for the complexation of metal ions [19] SBs and their complexes are largely studied because they interested and...
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báo cáo hóa học: " Structural and thermal studies of silver nanoparticles and electrical transport study of their thin films" pdf
... the design of the study and performed the electrical studies SK and MA carried out the structural studies SAA and MSA performed the thermal studies MAMK and MA also involved in writing of the manuscript ... observed The copper and the carbon peaks correspond to the carbon coated copper grid of TEM No peaks of other impurity have been detected Therefore, the EDX profile of sample (inset of Figure 2) indicates ... http://www.nanoscalereslett.com/content/6/1/434 Page of A B Figure FETEM and HRTEM images of silver nanoparticles (a) FETEM image of silver nanoparticles (b) High-resolution image of a single silver nanoparticle and inset shows...
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báo cáo hóa học:" Structural, optical and magnetic studies of manganese-doped zinc oxide hierarchical microspheres by self-assembly of nanoparticles" docx
... reports as well [31] The XPS data of Zn2p and Mn2p further provide evidences for the incorporation of Mn2+ ions into ZnO To obtain a better understanding of the formation of Mn-doped ZnO HMSs, a probable ... coordination route of EG which directs the formation of Mn-doped ZnO HMSs in view of morphology transformation A lot of EG molecules are adsorbed on the (001) surface of the ZnO crystals and block the ... spectra The origin of the peaks at 425 and 475 nm could be ascribed due to the transition occurring from Zn interstitials to the valence band, and the peak of 425 nm may be the result of the singly...
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Báo cáo hóa học: "Synthesis and Spectral Studies of CdTe–Dendrimer Conjugates" docx
... method of functionalizing QDs is simple and can avoid complicated synthesis and characterization of the intermediate products of QDs, when reactions are performed on the QD surfaces A number of reports ... nm) determined from the correlation of particle size and optical band gap Further, average size and size distribution of CdTe QDs obtained from UV spectra and TEM image were also supported by ... binding constants KSV and Kb and binding stoichiometry of the complex (n) have been determined Significant differences on the values of binding constants for dendrimers of different generation...
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Báo cáo vật lý: "Volumetric and Thermodynamic Studies of Molecular Interactions in Ternary Liquid Mixtures at 303, 308 and 313K" pptx
... oxygen atom of the ketone (cyclohexanone) and the proton of the hydroxyl group of the alkanol – R – O… H – O – Volumetric and Thermodynamic Studies 106 Furthermore, the addition of N, N-dimethylformamide ... were evidently due to the rupture of the hydrogen bonds in pure cyclohexanone and 1-alknaols and DMF-DMF, dipole-dipole interactions, and the formation of O–H…C=O and perhaps even O–H ….N(CH3)2 ... concentrations, and this has been interpreted to arise from the presence of strong or weak interactions The extent of deviation depends upon the nature of the constituents and composition of the mixtures...
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Báo cáo y học: "Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis" pdf
... lupus nephritis from randomised trials and observational studies Materials and methods QUOROM (quality of reporting of meta-analyses) and MOOSE (meta-analysis of observational studies in epidemiology) ... maximum of five points were awarded to studies according to whether they were randomised, double-blind, and accounted for withdrawals or drop-outs and to whether the methods of randomisation and ... trial) and over a treatment duration of up to years Despite this, there is the possibility of residual bias in observational studies and lack of blinding in randomised trials The amount of information...
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- physiological pharmacological and genetic modulation of tag mobilization
- and development studies of hpai cmu 2008
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- doh thesis of doctor experimental and theoretical studies of normal and high strength concrete wall panels griffith university
- thermal strain and magnetization studies of the ferromagnetic heusler shape memory alloys ni2mng
- evolutionary scaling and modeling studies of c02 and stress interactions
- expression purification and biophysical studies of chromodomain proteins
- molecular biochemical pharmacological and functional analyses of zebrafish coxs
- pharmacological and physiological effects of ginseng
- experimental basis and clinical studies of brain protection in pediatric heart surgery
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- gas amp 8212 historical perspectives current research and case studies of phosgene exposure
- isolation and functional studies of human fetal gastric epithelium in primary culture
- buck rongsong liu jiangping shuai jianhong wu huaiping zhu modeling and simulation studies of west nile virus in southern ontario canada
- range cell tropism and evolution studies of canine and feline parvoviruses minute virus of mice porcine parvovirus and aleutian mink disease virus
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng 9 tr 25