... L.: Sleep disturbances and excessive daytime sleepiness in Parkinson disease: an overview Arnulf, I.: Sleep and wakefulness disturbances in Parkinsonsdisease ... outstanding scientists and clinicians, Toshiharu Nagatsu, Yoshikuni Mizuno, Japan (Award of the WFN Research Group on Parkinsonism andRelated Disorders), Saskia Biskup, Germany and Andrew B Singleton, ... Diseaseand Parkinsonism seen at the Columbia-Presbyterian Medical Center from 1949 to 1964 Nearly 85% had classic ParkinsonsDiseaseand 13% had post-encephalitic associated Parkinsonism This...
... PARKINSONSDISEASE Figure 16 Parkinsons disease: dystonic posturing of the big toe secondary to dopa therapy 15 16 AN ILLUSTRATED POCKETBOOK OF PARKINSONSDISEASE Figure 17 Parkinsons disease: ... Posture in later-stage Parkinsonsdisease AN ILLUSTRATED POCKETBOOK OF PARKINSONSDISEASE Figure 12 Parkinsons disease: impaired fist clenching 11 12 AN ILLUSTRATED POCKETBOOK OF PARKINSONS ... RD, Bakay RA Neurosurgical horizons in Parkinsonsdisease Neurology 1993;43:l–7 Parkinson'sdisease Any discussion of the clinical characteristics of Parkinsonsdisease must take into account...
... Figure 14 Positive glabellar tap Persistent blinking is a feature of Parkinsons disease, but is also seen in Alzheimer sdisease Figure 15 6-[18F]-fluorodopa–PET scan appearance in a normal subject ... cells (astrocytes and macrophages) Debris and a few vascular channels can be seen (Luxol fast blue–H & E) Figure 24 CT of a patient with a Parkinsonian syndrome shows multiple lacunar infarcts ... Histological sections from Parkinson'sdisease with dementia showing cortical Lewy bodies stained with ubiquitin (immunochemistry preparation, left; silver impregnation, right) Figure 28 Histology...
... PARKINSON'SDISEASEAND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN CURRENT CLINICAL PRACTICE ParkinsonsDiseaseand Movement Disorders: Diagnosis and ... disorders On the island of Guam, amyotrophic lateral sclerosis, parkinsonism, and dementia occur in various combinations, perhaps as manifestations of the same disease process Outside Guam, the association ... paresis, however, has sinister implications; it is typical of certain multisystem cerebral disorders, such as progressive supranuclear palsy, variants of Niemann-Pick disease, and, sometimes,...
... dementia caused by medical conditions such as head injuries, diseases caused by the human immunodeficiency virus (HIV), Parkinsons disease, and Huntington s disease; and substance-induced persisting ... OF FOCUS: ALZHEIMER SDISEASEANDRELATED DISORDERS A gradual loss of memory, affecting a person s skills and behavior, characterizes Alzheimer sdisease In Helen s case, she slowly lost her ... is essential in transmission of nerve impulses through the synapses of the brain and central nervous system (A synapse is the point at 33 LIFE OUT OF FOCUS: ALZHEIMER SDISEASEANDRELATED DISORDERS...
... Cognitive screening includes using validated screening instruments, such as the MMSE, and brief bedside assessments Cognitive screenings are usually sensitive to significant cognitive impairment associated ... Psychiatric Press, 2000 66 Morris JC, Mohs RC, Rogers H, et al Consortium to establish a registry for Alzheimer sdisease (CERAD) clinical and neuropsychological assessment of Alzheimer sdisease ... tests.33 Medical/Psychiatric/Surgical Histories and Review of Systems Gathering information about previous episodes of memory loss, mood or other psychiatric disorders, and medical conditions and...
... disorders These diseases are conventionally categorized into either hypokinetic disorders, such as Parkinsons disease, or hyperkinetic disorders such as hemiballism or drug-induced dyskinesias ... disorders such as Huntington sdisease (HD) or dystonia, which seem to cross the boundary between these diseases Another common misconception is that movement disorders are basal ganglia diseases ... pathophysiology of common human movement disorders such as Parkinsonsand Huntington s diseases (PD/HD) These structures classically include: 1) the striatum, which comprises the caudate nucleus (CD),...
... diagnose is gold standard, rest conform to class 1A NINCDS–ADRDA = National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer sDiseaseandRelated Disorders Association ... diagnose is gold standard, rest conform to class 1A NINCDS–ADRDA = National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer sDiseaseandRelated Disorders Association ... individuals; IA = neuropathologic diagnosis is gold standard, rest conform to class 1A NINCDS–ADRDA = National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer sDiseaseand Related...
... SOD1 G93A and wild-type control mice at age ~8 weeks, ~10 weeks, ~12 weeks, and ~13 weeks Discussion Gait disturbances are characteristic of Parkinson's disease, Huntington 's disease, and amyotrophic ... image analyses The treadmill belt was wiped clean between studies if necessary Statistics Data are presented as means ± SE ANOVA was used to test for statistical differences among saline-treated, ... in Parkinson'sdiseaseand Huntington 'sdisease Mov Disord 1998, 13:428-437 Blin O, Ferrandez AM, Serratrice G: Quantitative analysis of gait in Parkinson patients: increased variability of stride...
... Although Parkinsonsdisease is most prominently identified with physical symptoms such as tremors and akinesia, this disease has a substantial impact beyond motor impairment and physical disability ... approach, and to assess the relationship between health utility scores and PD severity as measured using standard disease- specific tools In cross-sectional analyses, we identified ADL -related components ... diabetes mellitus [20], coronary artery disease [21], stroke [22] and arthritis [23] PD severity was assessed using UPDRS ADL and motor sub-scores (UPDRS II and III) [11], the Hoehn and Yahr Score...
... previously.64, 80, 81 Statistical analysis Responsiveness of PDQ-8SI scores was assessed using responsiveness indices including Cohen s effect size (ES)84, the standardized response mean (SRM)85 and ... national institute of neurological disorders and stroke PD - Parkinsonsdisease PDQ-8 - the 8-item Parkinsonsdisease questionnaire PDQ-8SI - the 8-item Parkinsonsdisease questionnaire summary ... living SD - standard deviation SF-36 - the short form 36 health survey SGD - Singapore dollars SLR - simple linear regression SRM - standardized response mean UPDRS - unified Parkinsons disease...