... methods are available that allow to distinguish the true insulin from the proinsulin True insulin may be lower than total insulin by 15–20% Acute Insulin Response to Glucose (AIRG) AIRG following glucose ... the hyperinsulinemia of insulin resistance may result from an increase in insulin secretion secondary to increased -cell sensitivity to glucose, as well as a decrease in insulin clearance In type ... due to mutation in the insulin receptor resulting in diminished tyrosine-kinase activity (type A syndrome) Others are due to antibodies to the insulin receptors which prevent insulin Etiological...
Ngày tải lên: 09/08/2014, 15:20
... MAP-K>mitogen-activated protein kinase; PC-1>an ecto-protein kinase probably interfering with insulin receptor tyrosine kinase; PI3-K>phosphatidylinositol-3 kinase; PIP2>phosphatidylinositol-4,5-P; PKA>protein ... PKA>protein kinase A; PKB>protein kinase B; PKC( , )>protein kinase C, forms and ; PKC>protein kinase C; PLC> phospholipase C; Shc>protein containing a single SH2 domain, substrate of insulin receptor ... contributing to insulin resistance both in type diabetes and in obese insulin-resistant Pima Indians It has been suggested that insulin action may be modulated by blood flow Insulin resistance in moderately...
Ngày tải lên: 09/08/2014, 15:20
New Concepts in Diabetes and Its Treatment - part 3 docx
... insulin, obtained by adding the protein protamine to insulin and adjusting the pH (c) The long-acting insulin preparations include the ultralente insulin, obtained by modifying, during the preparation, ... regular insulin as well as the semilente insulin which is a suspension of insulin and zinc in acetate buffer (with formation of zinc-insulin crystals) (b) The intermediate-acting insulins comprise ... of zinc and insulin to produce larger zinc-insulin crystals (the larger the crystals, the slower the release of the injected insulin) as well as the protamine-zinc insulin obtained by adding...
Ngày tải lên: 09/08/2014, 15:20
New Concepts in Diabetes and Its Treatment - part 4 ppsx
... immunogenicity of insulin Belfiore/Iannello 86 Table Factors in uencing the formation of insulin antibodies Insulin species (human insulin is less immunogenic than animal insulins) Insulin purity (monocomponent ... Altered Insulin Responses Conditions of altered insulin responses include: (a) insulin resistance linked to occult infections; (b) iatrogenic hypoglycemia or factitious inten- Insulin Treatment in ... (monocomponent insulins are less immunogenic) Insulin pharmaceutical form (regular insulin is less immunogenic than modified insulins) Pattern of insulin treatment (episodic therapy and CSII may increase insulin...
Ngày tải lên: 09/08/2014, 15:20
New Concepts in Diabetes and Its Treatment - part 5 pdf
... cause insulin resistant diabetes, can in some patients act as insulin-like factors); (e) ectopic insulin secretion (2) Sepsis (cytokines associated to endotoxinemia increase insulin release) (3) Insulin ... Glucagon test Vigorous exercise during fasting Proinsulin determination Leucine test Search for antibodies to insulin Search for autoantibodies against insulin or insulin receptors hormones, drugs ... excessive insulin response in children susceptible to leucine and in about 70% of patients with insulinoma (12) Search for antibodies to insulin (if present in persons not receiving insulin therapy...
Ngày tải lên: 09/08/2014, 15:20
New Concepts in Diabetes and Its Treatment - part 6 pot
... retinopathy Retinopathy Inside the retina (background retinopathy) Not vision-threatening In front of the retina (neovascularizations) Simple Vision-threatening Maculopathy Proliferative retinopathy ... retinopathy has resulted in vitreous haemorrhage or retinal traction from connective tissue in the new vessels, there is indication for vitrectomy During vitrectomy, thin instruments are introduced ... During ophthalmoscopy the retina is illuminated continuously, and inspection is either done directly or indirectly through a lens positioned with its focal point in the pupil plane of the examined...
Ngày tải lên: 09/08/2014, 15:20
New Concepts in Diabetes and Its Treatment - part 7 pdf
... VLDL secretion; TG (Lovastatin, 10–80 mg/day) (Pravastatin, 10–40 mg/day) (Simvastatin, 5–40 mg/day) (Fluvastatin, 20–40 mg/day) (Atorvastatin, 10–80 mg/day) (Cerivastatin, 0.1–0.3 mg/day) Probucol4 ... in particular ACE inhibitors, is moving from the indication of elevated BP to the indication of increased or increasing UAE as proposed in recently published guidelines Combination therapy is ... Hypertension in Europe Thrombolysis and Angioplasty in Myocardial Infarction Thrombolysis in Myocardial Infarction Trandolapril Cardiac Evaluation Scandinavian Simvastatin Survival Study Cardiovascular...
Ngày tải lên: 09/08/2014, 15:20
New Concepts in Diabetes and Its Treatment - part 9 pdf
... TSH) Instrumental investigations (penile biothesiometry and cardiovascular tests) Vascular evaluation (office-intracavernosal injection test) attention to their patient’s smoking and drinking habits ... changes in recent months and the description of the sexual intercourse itself Instrumental Investigations The instrumental investigations indicated include those used to examine the vascular ... Multifactorial Intervention in Type Diabetes mellitus 231 Insulin Insulin treatment can be given as monotherapy or as combination therapy with insulin and oral hypoglycaemic agents From studies comparing...
Ngày tải lên: 09/08/2014, 15:20
báo cáo hóa học:" Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases" pdf
... Rhinovirus infections Human rhinovirus (HRV) causes over 80% of the common cold in the fall [14] Developing vaccines against HRV is unfeasible because HRVs have at least 115 antigenically distinct ... of rhinovirus serotypes in human cells in vitro [1921] Administration of soluble ICAM-1 and MAbs in human clinical trials had indeed achieved reduction in symptoms, but did not prevent the incidence ... Unfortunately, even natural RSV infection produces limited immunity at best In fact, an inactivated RSV vaccine paradoxically resulted in more severe disease instead of protection [7] The most...
Ngày tải lên: 20/06/2014, 04:20
Mẫu công văn thực hiện chế độ tại Nghị định số 159/2006/NĐ-CP và Nghị định số 11/2011/NĐ-CP pdf
Ngày tải lên: 20/06/2014, 22:20
Quantitative Models in Marketing Research Chapter 3 pdf
... the maintained assumptions for the unobserved error variable "t in (3.7) are violated or that the functional form (which is obviously linear in the standard Linear Regression model) is inappropriate ... straightforward guidelines to be followed 34 Quantitative models in marketing research 3.2 Estimation In this section we briefly discuss parameter estimation in the standard Linear Regression model We first ... potentially useful explanatory variables In case of sales, variable x1;t can for example be price, variable x2;t can be advertising and variable x3;t can be a variable measuring promotion To simplify...
Ngày tải lên: 06/07/2014, 05:20
các giao thức sử dụng và định tuyến trong mạng voip [compatibility mode]
... chọn: final(v) =False Độ dài từ nguồn đến v: d(v)= , v N Đỉnh trước v: Truoc(v)=0 Nguồn a: final(a)=True, d(a)=0, Truoc(a)=0 N Final(v)=Fals e Y N Không tồn đường final(i)=false d(v)=min{d(i)/i ... N Final(v)=Fals e Y N Không tồn đường final(i)=false d(v)=min{d(i)/i N} Y u=v,d(u)=min,final(u)=True final(v)=false d(v)>d(u)+d(u,v) N Kết thúc Y d(v)=d(u)+d(u,v) Truoc(v)=u 19 Kết luận Phần ... Kết nối PC mạng IP Cấu trúc kết nối VoIP PSTN H.323 gateways Đầu cuối H.323 Modem Mạn g IP H.323 gateways Mạng IP Modem Hình 4: Kết nối thoại PC (PC - to - PC) nằm hai mạng IP khác Đầu cuối...
Ngày tải lên: 09/01/2015, 10:34
Bài 8 tổng cầu và chính sách tài khóa final compatibility mode
... tùy thuộc Δ 11 AE = AE0 +aY 10 II Tổng cầu kinh tế Tính ΔC, ΔI, ΔG? Tổng cầu mơ hình Keynes định nghĩa tổng chi tiêu dự kiến có khả toán tác nhân kinh tế ứng với mức thu nhập quốc dân định AEclose ... Đầu tư khu vực tư nhân (I= Investment) bao gồm: Đầu tư cố định vào SXKD Đầu tư vào nhà Đầu tư vào hàng tồn kho I phụ thuộc vào : r: lãi suất thực tế (học vốn vay) MPK: sản phẩm cận biên ... giá d hộ gia đình, doanh nghiệp phủ định chi tiêu nhiều mức giá e kinh tế giai đoạn suy thoái 20 Company Logo Bài tập Xét kinh tế đóng có tham gia phủ Tiêu dùng tự định 300 triệu đồng xu hướng...
Ngày tải lên: 18/03/2016, 12:42
Thay vinh dieu tri va phong ngua thuyen tac phoi compatibility mode
... chích (Loại 1B): Heparin TLPTT (LMWH) Fondaparinux Heparin KPĐ (UFH) tiêm da TTM TL:Chest 2012;141;e419S-e494S 28 Đt phòng ngừa thuyên tắc phổi LMWH fondaparinux > UFH (Loại 2B, 2C) ... fondaparinux enoxaparin: không khác biệt thuyên tắc huyết khối tái phát, chảy máu tử vong sau tháng Matisse – PE: so sánh fondaparinux UFH TTM liên tục: thuyên tắc tái phát cao UFH so với fondaparinux ... UFH TTM liên tục: thuyên tắc tái phát cao UFH so với fondaparinux (5.0% so với 3.8%) TL: Clin Interv Aging 2009;4:165-177 30 Đt phòng ngừa thuyên tắc phổi TL: European Heart Journal (2008) 29,...
Ngày tải lên: 16/09/2017, 15:51
Bài giảng concepts in enterprise resource planning (2nd edition) chương 3 hệ thống thông tin về marketing và quy trình quản lý đơn hàng
... hoạt động marketing như: sales calls, visits mailing • Thơng tin khách hàng đơn hàng lưu trữ ERP giúp định hướng hoạt động marketing công ty Concepts in Enterprise Resource Planning, Second ... chiến dịch marketing đánh giá hiệu Concepts in Enterprise Resource Planning, Second Edition 44 Core CRM Activities • Marketing Encyclopedias: • Tập hợp loại / mơ hình khuyến • Thơng tin hữu ích ... Based on total value • With or without shipping • By customer or customer class Concepts in Enterprise Resource Planning, Second Edition 38 Pricing Net price for order, including discounts Base...
Ngày tải lên: 14/04/2016, 15:09
Quản lí quan hệ khách hàng CRM và Email Marketing
... u cầu LINFO (Lean Information System): - LINFO (Lean Information System) dự án phần mềm Công ty Xi măng Holcim Việt Nam, Công ty Votiva triển khai Microsoft Dynamics CRM 4.0 (MS CRM) LINFO tận ... liệu bán hàng qua mạng Một số ứng dụng thành cơng CRM: Oracle Marketing: - Gồm: • Marketing (tiếp thị sản phẩm) • Trade Management (Quản trị kinh doanh) - Dòng sản phẩm Oracle giúp bạn hoạch định ... Resources Planning) :hệ thống thông tin hoạch định nguồn lực doanh nghiệp Với ERP, việc tích hợp quy trình kinh doanh, chia sẻ thơng tin phòng ban chức năng, cơng đoạn tồn quy trình hoạt động kinh doanh...
Ngày tải lên: 08/04/2013, 00:52
Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... structure [9] Accumulating evidences indicate that HSPGs act to inhibit cellular invasion by promoting tight cell–cell and cell–ECM interactions, and by maintaining the structural integrity and self-assembly ... signaling capacity The existence of a C-terminus domain (C-domain) emerged from a prediction of the 3D structure of a single-chain heparanase enzyme [73] In this protein 3894 variant, the linker ... prolonged in cells transfected with a mini gene comprising this segment linked to the C-domain sequence (8-C) [73,78] This finding further supports the predicted 3D model, indicating that the C-domain...
Ngày tải lên: 15/03/2014, 23:20
New Developments in Biomedical Engineering 2011 Part 2 doc
... Tarvainen, M & Karjalainen, P (2008) Tracking single-trial evoked potential changes with Kalman filtering and smoothing, 30th Annual International Conference of the IEEE Engineering in Medicine ... training purposes Each event (M1, T1, A2, P2 and background) is modeled by its own HMM and training can be done by HMM concatenation Non-Stationary Biosignal Modelling 47 according to the labeling ... shown in figure An incoming pattern is classified according to a pre-trained dictionary of models These models are in the present case HMM’s, each one modeling each event in the phonocardiogram...
Ngày tải lên: 21/06/2014, 19:20
New Developments in Biomedical Engineering 2011 Part 3 ppt
... assuming an important role in modeling of biological signals is stochastic differential equations (SDE) modeling These models are natural extensions of classic deterministic models and corresponding ... estimation In Section we propose two models: classical in which the gas exchange is modeled using ordinary differential equations, and stochastic in which the increments in gas numbers are modeled ... amenable to biomedical signal processing due to its ability to account for internal variability In the respiratory modeling in addition to breathing the main source of variability is randomness of the...
Ngày tải lên: 21/06/2014, 19:20