of the start up and its product

... start up In this book we emphasise the verb ‘starting up to mark a turn of attention to the dynamic nature of the phenomenon examined As a start up is in many ways its relationships, starting up ... technologies and products Start up companies often aim at commercialising a science-based discovery or invention that needs to be transformed into a commercial product The start up s own research ... V: Start ups and the Role of Policy Actors The chapters in this section (Chaps and 10) focus on the role of policy actors and the effects of policy support of start up companies Start ups generally...

Ngày tải lên: 03/02/2017, 15:22

... the vocabulary system in expression 2.2.7.2 Phrases 2.2.5 Pragmatics In grammar, a phrase is a group of words functioning as a Pragmatics is a subfield of linguistics which studies the ways single ... minimal syntactic relation to the words that precede or follow it A sentence can include words grouped meaningfully to express a statement, question, exclamation, request or command Sinclair [41, ... study are described The source of data and how they are analysed hospitality, warm debate, warm support or warm manner are used are included Chapter Four presents the findings and discussion on...

Ngày tải lên: 26/11/2013, 13:21

... bountiful supply of clothing She also superintended the purchase of materials for women's handiwork, apparatus for preserving botanical specimens, water colors and oil paints, books and school supplies; ... flakes It made pictures for Georgia and me upon the branches of big and little trees; it gathered in a ridge beside us upon the log; it nestled in piles upon our buffalo robe; and by the time our ... tree Whereupon, his companions, instead of seeking food, crept forth and broke off low branches, put them down before the fire and laid their attenuated forms upon them The flames leaped up the...

Ngày tải lên: 31/03/2014, 13:20

Ngày tải lên: 18/07/2014, 22:48

... the presence of CREB1 siRNA [17] Tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10; TRAIL) is a tumor necrosis factor superfamily member, and induces apoptosis through its interaction ... the copy numbers of BCL11B, a duplex vector, including a fragment of the BCL11B and the b2 microglobulin (b2M) genes was constructed and used as a reference (the duplex vector was a gift from Prof ... Specific peak of the BCL2L1 gene begins at 84°C D: PCR products of the b2M gene by 2.5% agarose gel electrophoresis analysis The size of the PCR products of the b2M gene used for the BCL11B reference...

Ngày tải lên: 10/08/2014, 22:21

... hippocampus, which control CRH production and limiting the period of exposure to the stress response, therefore minimizing the catabolic immunosuppressive and anti-reproductive effects of glucocorticoids ... Reproductive function Systems activated by stress can influence reproduction at the hypothalamus, pituitary gland or gonads There are close relations with the sustained activity of the end -product ... the pituitary gonadotroph [72] Furthermore, suppression of the growth, reproduction and thyroid functions arises from glucocorticoid ability to suppress the 5' deiodinase, which functions to...

Ngày tải lên: 13/08/2014, 14:20

... perspective upon what is taken to be a unified society in which all share the same timescale and appreciate its careful warning pace It tends to suppress a notion that different social groups may ... self-employed; they may keep a small shop for members of the group to which, culturally, they belong or supply a service to the group, for example as a 'cobbler', 'barber', 'grocer', 'bike-mender' ... Development (1934) The book advances the idea that the entrepreneur disrupts the circular flow of money and production by introducing a new product or process into the economy." (xi) A more incisive summary...

Ngày tải lên: 11/09/2015, 21:33

... Sympatric Species of Leaf-Toed Geckos (Gekkonidae: Phyllodactylus) from the Balsas Region of the Upper Marañón Valley, Peru 107 Materials and Methods 109 Phyllodactylus thompsoni ... GENUS POLYCHRUS 150 4.1 A new bush anole (Iguanidae, Polychrotinae, Polychrus) from the upper Marañon basin, Peru, with a redescription of Polychrus peruvianus (Noble, 1924) and additional ... habt, wenn es notwendig war! I am indebted to Prof Wolfgang Böhme and Prof Wolfgang Wägele for supervising my thesis Prof Wolfgang Böhme I further would like to thank for many fruitful discussions...

Ngày tải lên: 19/11/2015, 15:51

... the interest of the pharmaceutical industry towards natural products (Newman et al., 2003) Yet today, natural products continue to occupy a preponderant place among biologically active molecules: ... Streptomyces 2.2.4 Immunosuppressants These compounds suppress the immune response to prevent the rejection of grafts and transplants or to control autoimmune diseases Two important immunosuppressive agents ... catalyzed by a ketoreductase, the keto group is converted into a hydroxyl group In the second step, catalyzed by a dehydratase, dehydration eliminates the hydroxyl group and there is formation of a double...

Ngày tải lên: 19/05/2016, 11:22

... Raising Capital for Start -Up and Early-Stage Companies and the document production template-modules, of Financial Architect® were the perfect vehicles for bringing me up to speed Within days I ... our ―Start -up clients engaged through our investment banking advisory services division Some of our ―Start -up entrepreneurial clients can become too dependent on us Most ―Start -up clients ... equity groups) simply does not work for most start -up, early-stage or seasoned smaller companies When it does work for the very few, there is often too much equity and control given up to make...

Ngày tải lên: 30/10/2014, 17:10

... Superdex 200 (2.6 · 60 cm, Pharmacia) to give 30 mg of virtually pure protein Snz1p without a His-tag Harvested cells were processed in a way identical to that for Sno1p up to the cell disruption ... The pellet was taken up in 50 mL of the same buffer and mL of Triton X-100 and shaken at room temperature for 30 The suspension was centrifuged (17 000 g) for 30 and the supernatant discarded ... surface of synthetic medium plates supplemented with pyridoxine and the growth requirements, and the plates were incubated at 30 °C The colonies that appeared on the supplemented plates were then transferred...

Ngày tải lên: 19/02/2014, 12:20

... chloroquine to visualize any changes in superhelical density arising from TSA/hormone treatment Treatment with TSA decreased the negative superhelicity by 1.5 superhelical turns, equal to 1.5 nucleosomes ... to remove insoluble debris Supernatant, equivalent to one nucleus, was used for immunoprecipitation Acetylated histones were immunoprecipitated for h with anti-AcH3 (Upstate Biotechnology), H3 ... DNA topology assay as the loss of negative superhelical turns [20] These alterations in DNA topology take place even if histones are not physically disrupted from the chromatin template [29] Oocytes...

Ngày tải lên: 19/02/2014, 12:20

... molar excess of uPA for 30 Reaction products were analysed by nonreducing SDS/PAGE followed by staining with Coomassie brilliant blue The migration of the uPA–PAI-1 complex, uPA, intact (inert) ... behaving as a Fig Reaction products following reaction of PAI-1 variants with uPA PAI-1 variants (100 lgÆmL)1), indicated by their amino acid substitution, were reacted with uPA (200 lgÆmL)1) at 37 ... 7.4 for 30 and the products were separated by nonreducing SDS/PAGE (11% acrylamide) followed by staining with Coomassie brilliant blue The migration of the uPA–PAI-1 complex, uPA, intact (inert)...

Ngày tải lên: 20/02/2014, 11:20

... for 15 The cell suspension was disrupted using an ultrasonic processor (VP-5, TAITEC) on ice The E coli lysate was centrifuged at 26 000 g for 30 at °C The supernatants containing recombinant ... fungal PPases including AsPPase represent a separate group from plant and prokaryotic PPases Furthermore, within the animal/fungal subgroup, AsPPase is more closely clustered with PPases from ... and reproductive organs, of adult female worms suggests a critical role of the enzyme in these organs The presence of AsPPase in embryonated eggs, L3, lung-stage L3, adult worms and their ES products...

Ngày tải lên: 20/02/2014, 11:20

... equilibrium The supply side similarly accounts explicitly for the production of two and three products (before and after the GM innovation, respectively) The quality enhancement of organic production ... the form of farmer-supplied effort, and that this required extra labour input has an upward-sloping supply This is certainly consistent with the observation that organic production is typically ... and, when coupled with the additional effort requirement for organic production, provides an effective representation of the different supply responses of conventional and organic production An...

Ngày tải lên: 05/03/2014, 20:20

... the markers are labeled on the left Arrows indicate specific gene products translated product Furthermore, VBARP-S exhibited protein products of 49 and 55 kDa, further confirming the possibility of ... and VBARP-S exhibited a distinct cytoplasmic pattern upon expression Similar cytoplasmic distribution was observed in 293 and A172 cells upon transfection with VBARP constructs (data not shown) ... interaction studies Ten microliters of 35S-labeled in vitro translated VBARP and Vpr or Nef (as control) products were mixed and immunoprecipitated with VBARP-, Vpr- or Nef-specific antibody and analyzed...

Ngày tải lên: 07/03/2014, 21:20

... pantetheine moiety has an ester linkage to a pivalate group instead of 3¢-phospho-ADP In OPP, the reactive SH group of SPP is further replaced by an OH group In CoA, certain atoms of the pantetheine moiety ... Acta Cryst D60, 2288–2294 Supporting information The following supplementary material is available: Fig S1 Electron densities of ligands in the crystal structures This supplementary material can ... Z ramigera, concentrating specifically on the SH groups of the substrate and the catalytic Cys89, which is conserved throughout the thiolase superfamily The results obtained indicate that the sulfur...

Ngày tải lên: 16/03/2014, 04:20

... protein was obtained by using coupled in vitro transcription ⁄ translation (TNT) reaction The production of the full-length polypeptide was confirmed by analysing the product of reaction in the presence ... doses (ED50s) for JH I–III are 153, 678 and 143 pmolÆpuparium)1, respectively Another report describes that the ED50 of methoprene is pmolÆpuparium)1 in the same assay and that Met mutant flies ... the white puparial assay [42] whereas JH II is more active in our transfection assay The difference between these two studies is the concentrations of JH used Wozniak et al [42] used supraphysiological...

Ngày tải lên: 16/03/2014, 18:20

... hereafter underground), and R3 \ Ω The medium M occupying Ω, is a linear, isotropic, homogeneous, hysteretically-damped solid and the medium occupying R3 \ Ω is the vacumn M is associated with: ... a supposedly-rigorous solution (expressed by a double integral) of the boundary value problem of continuum elastodynamics in a linear, homogeneous, isotropic hysteretically-damped solid occupying ... Chotiros, 2002), and continued in such works as (Scotti & Wirgin, 2004; Buchanan et al., 2011; Dupuy, 2011) 1.1 Statement of the inverse problem As we shall see hereafter, the data takes the form...

Ngày tải lên: 18/03/2014, 01:21

... = 0, f (t, y(t + θ)) − f (t, z(t + θ)) (5) g(t) sup y(t + θ) − z(t + θ) , (6) −h θ ∞ g(τ )dτ m < ∞ (7) Let (T (t))t≥0 be a continuous semigroup of linear operators in the Banach space E and (A, ... [10]) Throughout this paper, we always assume that (T (t))t≥0 is strongly continuous semigroup (C0 - semigroup ) We show that if Eq.(4) satisfies conditions (5), (6), (7) then the solution of Eq.(4), ... Gronwall-Bellman’s lemma(see [12]), we can get the following result: Theorem 2.1 Suppose (T (t))t≥0 is C0 - semigroup with the generator (A, D(A)) The following assertions are true: (1) If T (t)...

Ngày tải lên: 22/03/2014, 11:20