new extra cellular mushroom enzymes which oxygenate aromatic compounds

... are often released in the extracellular medium Moreover, they can enter cells distinct from producing cells and modify gene expression in recipient cells [6-8] Extra- cellular transport of microRNAs ... nanovesicles of 50 to 100 nm in diameter which are derived from the late endosomal compartment and secreted by most eukaryotic cell types [11] Exosomes behave as extra- cellular carriers of microRNAs that ... exosomes released by NPC cells in vitro Several reports have shown that at least a fraction of extra- cellular microRNAs are secreted in association with exosomes [7,12,20] Therefore, we undertook...

Ngày tải lên: 12/08/2014, 01:22

... neuroblastoma 74 4.3.2 Differentiation of intra- & extra- cellular SBD from the membrane bound fraction 4.3.3 Differentiation between intracellular and extracellular SBD 75 78 4.3.4 Inhibition Rho GTPase ... measurements 76 Figure 4.3: Autocorrelation curves obtained for extracellular membrane bound intracellular signals 77 Figure 4.4: Extracellular vs cytosolic τD values for SBD 79 Figure 4.5: Flotillin-2 ... sphingolipid family Faulty intracellular trafficking or storage of sphingolipids and cholesterol can lead to an array of lipid storage diseases Therefore studies of sub -cellular movements of sphingolipids...

Ngày tải lên: 12/09/2015, 09:55

... THE INTRAMOLECULAR INTERACTIONS IN SOME AROMATIC COMPOUNDS Li Wei (B.Sc, Zhejiang University, China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... 21.22eV which was adequate to ionize most of the electrons from valence orbitals without serious auto-ionizations The helium lamp was used in conjunction with a retarding field analyzer, which ... HeI source opened a new page of applying UPS to studying the electronic structures of the molecules In 1970 Turner published the first handbook of HeI photoelectron spectra, which contains spectra...

Ngày tải lên: 11/09/2015, 16:07

... bacteria in aromatic biodegradation 11  Table 2-6 Bacterial utilization of aromatic compounds 14  Table 2-7 Enzymes associated with biodegradation of aromatic compounds (extracted from ... the benzene ring Some representative aromatic hydrocarbons are shown in Table 2-2 Table 2-2 Representative aromatic compounds in the environment Aromatic compounds Monocyclic hydrocarbons Representative ... the initial step, followed by the aromatic- ring oxygenation reaction (Figure 2-2b) 16 Table 2-7 Enzymes associated with biodegradation of aromatic compounds (extracted from Whiteley and Lee (2006))...

Ngày tải lên: 12/09/2015, 08:19

... DEVELOPMENT OF NEW METHODOLOGIES FOR THE SYNTHESIS OF ENANTIOMERICALLY ENRICHED COMPOUNDS LEE CHENG HSIA ANGELINE (B.ApplSc (Hons.), NUS) A THESIS ... Asymmetric Synthesis, Wiley, New York, 1995 (c) Ager, D J.; Prakash, J.; Schaad, D R Chem Rev 1996, 96, 835 17 Enantioselective Allyl Transfer In the next section, a new methodology to access enantiomerically ... states 26 also revealed the reason for the sluggish crotyl transfer reaction with aromatic aldehydes If R = aromatic aldehydes benzaldehyde for instance, we believed that the subsequent rearrangement...

Ngày tải lên: 16/09/2015, 08:30

... in quinoprotein and flavoprotein enzymes that catalyse the oxidation of a number of amine substrates, and computational studies of enzymic H-tunneling in these enzymes QUINOPROTEIN AND FLAVOPROTEIN ... (TTQ)-dependent amine oxidases methylamine dehydrogenase (MADH) and aromatic amine dehydrogenase (AADH), and also the flavoenzymes trimethylamine dehydrogenase (TMADH) and heterotetrameric sarcosine ... crystallographic structures are available for MADH and TMADH, which has also opened up complementary computational chemistry studies of H-transfer in these enzymes TTQ-DEPENDENT METHYLAMINE DEHYDROGENASE AND...

Ngày tải lên: 31/03/2014, 23:20

... gene because it encodes the surface unit (SU) glycoprotein, which plays a key role in viral entry and is a target of both humoral and cellular responses [9] These early SIV studies showed that ... a new host In a previous study, SIV variants were isolated from an infected animal at early, intermediate, and late stages of infection, and these sequential variants were used to infect a new ... infected with SIMneCL8, which had the fewest initial serine/threonine (N = 7), except in three clones from one animal (J95155) at 77 weeks These changes at 77 weeks, which included additional...

Ngày tải lên: 20/06/2014, 01:20

... short-term ambulatory extracorporeal membrane oxygenation J Thorac Cardiovasc Surg 2010, 140(3):713-5 Bermudez CA, Adusumilli PS, McCurry KR, Zaldonis D, Crespo MM, Pilewski JM, Toyoda Y: Extracorporeal ... doi:10.1186/1749-8090-6-52 Cite this article as: Souilamas et al.: Extra corporal membrane oxygenation in general thoracic surgery: a new single veno-venous cannulation Journal of Cardiothoracic Surgery ... Published: 14 April 2011 References Brogan TV, Thiagarajan RR, Rycus PT, Bartlett RH, Bratton SL: Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multicenter database...

Ngày tải lên: 10/08/2014, 09:21

... 13-hydroperoxides, CYP74C includes AOS and HPL which can convert either 9- and 13-hydroperoxides Finally, DES are classified as CYP74D [7] A new nomenclature for CYP74 enzymes, based upon the confirmed substrate ... and CYP74A1, plant cytochrome P450 enzymes whose activity is regulated by detergent micelle association, and proposed new rules for the classification of CYP74 enzymes Biochem Soc Trans 2006, 34:1223-1227 ... of recombinant proteins, has recently been proposed [8] and which assigns CYP74C to only HPLs with dual specificity As far as the endocellular distribution of CYP74 members is concerned, even if...

Ngày tải lên: 12/08/2014, 05:20

... been the discovery of phosphoproteins not previously known to be involved in cellular signaling and the discovery of new phosphorylation sites in known signaling proteins As enzymatic catalysis ... now being realized, a number of phosphoproteomic studies have already provided important new insights into cellular signaling refereed research Expanding the signaling parts list deposited research ... proteins detected, which were either phosphotyrosine interactions The combination of quantitative mass spectrometry and phosphoproteomics has generated powerful technologies for studying cellular signaling...

Ngày tải lên: 14/08/2014, 14:22

... intracellular cytoplasmic amino-terminal sequence of approximately to residues followed by a large extracellular loop (EL1) of 60 residues, a short 20-residue intracellular loop, another extracellular ... acids and, as such, is thought to influence paracellular charge selectivity [9] Two highly conserved cysteine residues are present in the first extracellular loop and are hypothesized to increase ... second extracellular loop, by virtue of its helix-turn-helix motif conformation, can form dimers with claudins on opposing cell membranes through hydrophobic inter­ ctions a between conserved aromatic...

Ngày tải lên: 14/08/2014, 21:20

... DEVELOPMENT OF NEW HUMAN STEM CELLDERIVED CELLULAR VEHICLES FOR GLIOMA GENE THERAPY ZHAO YING (B Sc., PKU; M Sc., PKU) A THESIS ... inoperable Normal brain tissue can tolerate up to 60 Gy of radiation, which is below the threshold required to kill glioma cells Several new technologies, including hyperfractionated radiation therapy, ... doublestranded DNA, which is then transported to the nucleus and randomly integrate into the host cell genome Retrovirus vectors are usually used in replication-deficient form, which is rendered...

Ngày tải lên: 11/09/2015, 09:00

... construct, classified as extra- role behavior Extra- role behavior is defined as behavior that benefits the organization and/or is intended to benefit the organization, which is discretionary and ... types of extrarole behaviors (such as ‘promotive’ vs ‘prohibitive’) rather than a more global extra- role behavior construct Based on their proposition, I attempt to extend the work on extra- role ... sharing (classified as a ‘promotive’ extra- role behavior) and whistleblowing (classified as ‘prohibitive’ extrarole behavior) not previously explored in past extra- role behavior research This dissertation...

Ngày tải lên: 12/09/2015, 11:24

... NEW CELLULAR AUTOMATA DESIGN BASED ON TRANSFORMATION SEQUENCE PROGRAMMING TAN SYN KIAT (B.Eng (Hons.), ... developed several theorems to support the design of new PRNG and the TSMLM concept can be applied with arbitrary PRNG under certain conditions vii The new Programmable Transformations (PT) scheme uses ... Chapter Introduction 1.1 Introduction to Work Presented in this Thesis Cellular Automata (CA) [1] are dynamic systems in which space and time are discrete A CA consists of an array of cells where...

Ngày tải lên: 16/09/2015, 08:31

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