... proteinases, andtheir function suggested to contribute totheir allergenicity Thus, a proteinase function of group I allergens could explain the high prevalence of allergic individuals sensitized to these ... dithiothreitol) and 0.3 mU N-glycosidase A were added to 10 lL expression supernatant (25 lg total protein) and incubated at 37 °C overnight Buffer alone served as the negative control Deglycosylated and ... Promega, Madison, WI, USA), and sequenced To construct the mutated form, fragments were released using the restriction enzymes SmaI and SnaBI or EcoRI and SnaBI, respectively, and both ligated in pBS,...
... (S-06381a), The Social- and Health Directorate (06/4509 and 06/4417) and The Data Inspectorate (06/01467-3) approved the study Table Ephrin A-1 and EphA2 immunostaining in relationto clinicopathological ... novel eph-related receptor protein tyrosine kinases in mammary gland development and carcinogenesis Oncogene 1994; 9: 1461-7 Holder N, Klein R Eph receptors and ephrins: effectors of morphogenesis ... CA, U S.A.) and Dakoautostainer After microwaving in 10 mM citrate buffer pH 6.0 to unmask the epitopes the sections were treated with 0.03% hydrogen peroxide (H2O2) for minutes to block endogenous...
... FOXA1 and FOXA3 interaction could be for technical reasons with regard to the Co-IP protocol Therefore, to detect and verify possible co-bindings andto further understand whether these are due to ... through ChIP and sequencing on the SOLiD platform Furthermore, we intended to examine their possible interactions with each other, with FOXA2, andtheir correlation with H3K4me3 and other TFs ... of FOXA3 bound to DNA, it was suggested that these factors bind as monomers and that the structure of FOXAs is similar to those of histones H1 and H5 [8] The latter is proposed to be the explanation...
... is believed to play a major role in mediating virus attachment and entry into hepatocytes [3] Within the preS1 protein, the 21–47 amino acid epitope was shown to mediate binding to the cell surface ... antibodies toward the three preS1 epitopes (21–32, 32–47 and 94–117) is associated with an enhanced response to HBsAg We found that recognition of several preS1 epitopes, and in particular, the epitope ... tested for safety and immunogenicity in adults and how to observe local signs and general symptoms associated with the vaccine administration The frequencies of all signs and symptoms (i.e vaccine...
... attempt to assess their relationship to canonical grapheme-colour synaesthesia Human Colour Processing As this thesis sets out to investigate and further understand the relationship between colour and ... between projector and associator subtypes, manifested as greater connectivity in inferior temporal cortex near the fusiform gyrus in projectors as compared to associators This has led to the idea ... processing and comparison of signals from three types of cone photoreceptors: short (S), medium (M), and long (L) cones, maximally sensitive to ~430 nm (corresponding to blue), ~530 nm (corresponding to...
... direct commitment to action, which to some organizations appears too demanding and unrealistic to adopt Thus, the trend for many industries is to opt for other less demanding and less stringent ... choose to become certified Clarity and consistency in the series definitions of various tools and strategies andtheir order of preference would make it easier for facilities to understand what ... standards Although the series were developed according to the mandate of their authors, many therefore believe that they not make enough of a commitment to the environment and, that in order to...
... (Table and 2) Thus, the bottom sediment was not a major factor leading to the different distribution of sea urchin in the outer and inner areas of the bay Restoration effort Water temperature and ... Arasaki, S and Tokuda, H (2002) Keys to the seaweeds of Japan and its vicinity Hokuryukan Press, Tokyo, pp 52 - 53 Deny, M W (1988) Biology and the mechanics of the wave - swept environment Princeton ... seaweed and aquaculture Midori Press, Tokyo, pp 133 - 144 Turner, M G., Gardner, R H and ÓNeill R V (2004) Landscape ecology in theory and practice: Pattern and process, Nakagoshi, N and Hara,...
... resembles a ¨ ¨ right hand: two b-sheets and the a-helix form fingers and a palm, a long loop between the B7 and B8 strands forms a thumb, and a loop between the B6 and B9 strands forms a cord (Fig ... Asp and Arg (Table 5) In NFX, the additional Arg160 is located on the protein surface, and Asp156 makes a double salt bridge with Arg58 (Oc1 and Oc2 atoms of aspartic acid and Ng1 and Ng2 atoms ... hydrogen bonding with b-strand A5 and the extension of b-strand B3 interacts with a b-strand B4 BAX also has a longer C-terminal b-strand A4 and a short additional b-strand after that When the three-dimensional...
... systems adapt toand increase their organization under the sti- formation of mulation of random environmental factors This theory has been applied extensively to the growth of organisms and transmission ... the autocross-linking of these cellulosic fibers during the production of paper and hardboard in the so called process (Back, 1987; Horn and Setterholm, 1988) In order to try to understand the ... suggested in rela- lics, such tion to the difficulties in completely removing tannins, after solvent and mild chemical extractions of woods and, also in relationto coprecipitation, such as sulfuric...
... score data and decision making in relationto treatment of metritis andtheir motivation to produce data This information was condensed into a 'model of understanding' that demonstrates the relationship ... study seemed to base both cow-level decisions and, to some extent, farm advice on personal judgements and tacit knowledge, despite their proclaimed intentions to base their daily practice to a higher ... connected to metritis treatment and potential links to data quality This understanding provides insight into potential errors (bias and random error) related to data based on clinical examina-...
... travelers Most of them seemed too closed, to be friendly and warmhearted, and welcome us They told us everything they did in Vietnam and they thought about Vietnam in their travels Therefore, they ... where have many tourist drinking beer there, very famous street with tourist We ordered a bottle of orange juice, drank and wait for a chance to access tourists And we got it Most of tourists here ... interview of 25 questions and divided into 10 main topics: Background Reason for travel Tourist sites visited or intending to visit Tourist services used Sources of information and how useful it was...
... β = V0/V (10) RED J/m Where: V= required volume of reactor to achieve same N/N0 as piston flow reactor; V0=volume of a piston flow reactor 450 400 350 300 250 200 150 100 50 0.00 0.50 1.00 1.50 ... 110 cm high and the reactors equipped with and lamps were made from a 210.3 mm (ID) stainless steel column 110 cm high, respectively Tap water was used as the feed to the UV reactors The tap ... Samples were taken before and after passing through the UV reactor at a range of measured flow rates The ratio of survivors to initial numbers was compared to Equation (8) and RED for each flow rates...
... two snapshots relative to the volume of total bonds outstanding For Greece, the net open CDS amount to around 3% of their outstanding sovereign debt and for Portugal and Ireland around 7% This magnitude ... Bhanot, K and L Guo (2010) Types of Liquidity and Limits to Arbitrage-The Case of Credit Default Swaps Mimeo Beber, A., M.W Brandt and K A Kavavejc (2009) Flight -to- Quality or Flight -to- Liquidity? ... and second a study of the arbitrage relationship between CDS and the underlying bonds In the first part, we study the common factors in the first differences of bond spreads and CDS spreads and...
... binds to ERBB3 and ERBB4 NRG1 and NRG2 bind to both ERBB3 and ERBB4, whereas NRG3 and NRG4 only bind to ERBB4 [3] Although these ligands show redundancy, heparinbinding-EGF is the only ligand whose ... Eleven ligands are known to bind to the ERBB family of receptors [3] These can be classified into three groups (a) ligands that specifically bind to EGFR (including EGF, transforming growth factor-a, ... regulatory domain are relatively low, being 33, 24 and 28%, respectively regulin and epigen); (b) those that bind to EGFR and ERBB4 (including betacellulin, heparin-binding EGF and epiregulin); and...
... systems providing services to population groups that have been neglected so far The study at hand is a first step towards it Remittances from Germany andtheir Routes to Migrants' Origin Countries ... Introduction More and more people are leaving their homeland in the hope of finding greater security and prosperity elsewhere Today, almost 200 million people live outside their country of origin.1 ... decided to stay in Germany for the medium or long term, andto bring their families over Since the end of the 1980s, there has also been an increasing flow of Moroccan students coming to Germany to...
... quarter is leisure, tourist and industrial centre; a thousand shops have been opened to serve tourism, satisfy tourist’s demand and they easily combine sightseeing and shopping Western tourists are ... where have many tourist drinking beer there, very famous street with tourist We ordered a bottle of orange juice, drank and wait for a chance to access tourists And we got it Most of tourists here ... interview of 25 questions and divided into 10 main topics: Background Reason for travel Tourist sites visited or intending to visit Tourist services used Sources of information and how useful it was...
... metalloproteinases and venom complexity J W Fox and S M T Serrano proteins are synthesized in the cytoplasm of secretory cells in the gland and transferred to the rough endoplasmic reticulum, and then ... von Willebrand factor promotes site-specific proteolysis of von Willebrand factor and inhibition of von Willebrand factormediated platelet aggregation FEBS J 274, 3611–3621 50 Kishimoto M & Takahashi ... spacer region, or linker as per their terminology, appears to be accessible to the solvent and contributes to the flexibility observed between the proteinases and the disintegrinlike domains [33]...
... ATP-NADH kinase; it was shown to be localized in the mitochondrial matrix andto be important to several NADPH-requisite mitochondrial processes, e.g resistance to a broad range of oxidative ... pos5 cell on SG solid medium and on and in solid and liquid media lacking arginine (Fig and Table 6), thereby supporting the partial contribution of Utr1p and Yef1p to mitochondrial functions (Fig ... Collectively, we assume that cytosolic CgLeu2p has the ability to utilize NADP and that it supplies cytosolic NADPH, whereas cytosolic ScLeu2p cannot provide NADPH due to its specificity to NAD In the triple...
... computes an update to the weight vector based on the current example The resulting weight vector tends to be overfit to the last few examples; one way to reduce overfitting is to use the average ... label, and for an incorrect link Since the history-based feature set used in the parsing algorithm makes it impossible to use independence to factorize the scoring function, an exact search to find ... and OPA There has been some work on machine learning methods where this parameter is tuned automatically (Tipping, 2001), and a possible extension to our work could be to adapt those models to...