mri of exercising skeletal muscle

... density of each skeletal muscle type in four different groups of mice In general the slow twitch soleus muscle had almost twice the mast cell density of both the EDL and gastrocnemius muscles ... cardiac muscle following screening of a large number of sections (20 fields at X 200 magnification for each mouse) http://www.journal-inflammation.com/content/1/1/2 Mast cell density of skeletal muscles ... Density An overview of mast cell content in the four groups of mice tested was obtained by counting a minimum of 100 mast cell profiles in tongue, skin and heart as well as skeletal muscle Using 100...

Ngày tải lên: 11/08/2014, 08:21

... levels of phosphorylated (inactive) FOXO3a have been observed in the skeletal muscle of cachectic compared with non-cachectic cancer patients, but an unexplained twofold reduction in the amount of ... global molecular profiling in the skeletal muscle of cancer patients and relate our findings to clinical status Page of 12 Methods Men and non-pregnant women over 18 years of age were recruited ... weight loss across a range of muscle tissues imply that these muscle groups develop dysregulation of calcium sensing or are burdened by greater loading in the face of failing muscle function connected...

Ngày tải lên: 11/08/2014, 12:20

... viscosity of the extract as a result of DNA, lL of DNase I (200 units) was added per 100 lL of buffer [30] Following filtration through two layers of miracloth and the addition of four volumes of ice-cold ... were of analytical grade and purchased from Sigma Chemical Company Preparation of total muscle extracts For the comparative gel electrophoretic analysis of normal vs dystrophic skeletal muscle ... presence of soluble proteins and underestimate the expression of membrane-associated proteins Despite these problems, the proteomics analysis of the protein complement of normal mouse skeletal muscle...

Ngày tải lên: 19/02/2014, 16:20

... of skeletal muscle Ca2+ release channel (ryanodine receptor) Biophys J 69, 106–119 Buratti R, Prestipino G, Menegazzi P, Treves S & Zorzato F (1995) Calcium dependent activation of skeletal muscle ... sites of skeletal muscle Ca2+ release channel Biophys J 70, 2600–2615 16 Herrmann-Frank A & Lehmann-Horn F (1996) Regulation of the purified Ca2+ release channel ⁄ ryanodine receptor complex of skeletal ... Regulation of the rat sarcoplasmic reticulum calcium release by calcium J Muscle Res Cell Motil 21, 131–138 20 Lai FA & Meissner G (1990) Structure of the calcium release channel of skeletal muscle...

Ngày tải lên: 19/02/2014, 16:20

... the TA muscle of normal mice One month after injection, direct observation of the skinned injected muscle using confocal fluorescence microscopy allowed the visualization of a high level of YFP ... standardization of the loading (D) Weights of injected TA muscles (n = 13) were compared to those of control samples No significant difference was observed (E) Histological analyses of muscles Frozen ... obtain denervation of the muscle of the lower limb, the dorsal skin of the thigh of 2-month-old male 129SvPasIco mice (n = for each time point) was cut, and the posterior muscles were split apart...

Ngày tải lên: 07/03/2014, 03:20

... Immunoblot of CK isoforms of different post-operative human tissues (A) Immunoblot of MCK (a) and sMitCK (b) of normal muscle (N) and fibrosarcoma (T) tissue (B) Immunoblot of BCK (a) and uMitCK (b) of ... ratio, and a decrease in the activity of CK and some of its isoforms in several different forms of cancer [15–20] Skeletal muscle tissue contains high levels of phosphocreatine, creatine and CK, ... of protein had to be applied compared with normal muscle sMitCK β-actin NM Detection of BCK and uMitCK isoforms in human gastric and colorectal adenocarcinoma tissues Fig Expression of mRNA of...

Ngày tải lên: 07/03/2014, 06:20

... the investigation of activity [27], the creation of antibody chimeras [28], and the study of Table The ratios of the volumes (V) of the models built by SAXS and of the structure of TnC(1–91) (1SKT) ... domain of TnC [33] The crystal structure of cTn [20] showed that residues R117 to L128 of TnI (in chicken fast skeletal numbers) are in close contact with the N domain of TnC in the presence of calcium ... terminus of TnI has a tubular-like conformation that involves the globular N domain of TnC NMR studies have provided additional information on the structure of skeletal TnC(1–91) in the presence of...

Ngày tải lên: 16/03/2014, 18:20

... Pressure-induced denaturation of actin (Eur J Biochem 269) 365 The aim of the present study was to complete a study of F ® G transition and denaturation of actin under pressure Use of a Hitachi F2000 ¯uorospectrophotometer ... centre of spectral mass of intrinsic ¯uorescence spectrum of G-actin with ATP (0.5 mgámL)1, pH 7.5) in a pressure range from 0.1 MPa to 400 MPa at a ®xed temperature of 20 °C The transition of the ... nm of eATPG-actin was higher than that of eADP±F-actin Both actins and eATP buffer showed an increase in intensity of ¯uorescence when exposed to a pressure of 250 MPa However, the increase of...

Ngày tải lên: 24/03/2014, 00:21

Ngày tải lên: 29/03/2014, 17:20

... identified as a partner of skeletal muscle titin-N2A [18] An analysis of CARP expression in the subcellular compartments Regulation of CARP by calpain obtained from the muscle of the mice injected ... the over-expression of CARP in muscle cells results in NF-jB p65 inhibition, it does not affect the expression of MURF1, which is one of the main mediators of NF-jB-dependent muscle atrophy [51] ... role in the control of transcription [17,19–21] Although the three MARPs are expressed in both heart and skeletal muscle [18,22,23], Ankrd2 is mainly expressed in skeletal muscle [18,24,25], CARP...

Ngày tải lên: 29/03/2014, 21:20

... expressed only in skeletal muscles, and promotes muscle differentiation if induced by MyoD and myogenin during myogenesis [16,17] These muscle- specific miRNAs seem to participate in muscle diseases, ... pathohistological features of each DM1 specimens used in this study (sex, muscle, lysosomal activity and muscle pathohistological aspects) Muscle biopsies from VL of female and males have been ... expression of miR-206 in cytoplasm both in normal and DM1 tissue, but no signals were visible, indicating a nuclear specific function of miR-206 in the muscle tissue As controls of hybridization, the muscle...

Ngày tải lên: 18/06/2014, 16:20

... is the mass of the testing end of myometer; amax is the maximal amplitude of oscillation, and ∆l is the depth of the displacement of the testing end Measurements for determination of muscle tone ... contribute in the diagnostics of the functional condition of the skeletal muscles and correlate it with certain criteria of the classical diagnostics Simultaneous measurements of intramuscular pressure ... of the skeletal muscle may provide new insights into muscle function and can help to diagnose the stage of pathological processes of muscles grip The testing end (mass 20 grams) of the computerized...

Ngày tải lên: 20/06/2014, 00:20

... properties of skeletal muscles, even within the physiologic range of the excursion of the muscle- tendon unit 22 Acknowledgements 23 The authors sincerely thank the National Science Council, Republic of ... the treatment and prevention of muscle strains Certain muscles (muscles that cross several joints or those with com- Table 2: Energy absorption of triceps surae muscle- tendon units during eccentric ... Disruption of the muscle fibers occurred initially, and disruption of the connective tissue occurred only with large displacements of the muscle [34] Our results are consistent with those of Kellis...

Ngày tải lên: 20/06/2014, 00:20

... a ramp filter and a cutoff frequency of 0.5 of the Nyquist frequency to obtain an image pixel size of 0.4 × 0.4 × 0.8 mm and an inter-plane spacing and slice thickness of 0.8 mm in a 128 × 128 ... administration corresponded to an increase in Ki for myocardium and skeletal muscle Because skeletal muscle constitutes a significant fraction of the body mass in mice [19], the observed insulin-induced ... regarding glucose metabolism between heart and skeletal muscle, indicate that myocardium and skeletal muscle might have different mechanisms for regulation of glucose or FDG uptake in response to insulinstimulation...

Ngày tải lên: 21/06/2014, 02:20

... the expression levels of muscle ring finger protein-1 (MuRF-1); that, like atrogin-1, is a muscle specific E3 ligase implicated in muscle atrophy [13] Taking advantage of a non-replicative, non-infectious ... gastrocnemius muscles with preserved type I fiber area in soleus muscles from a transgenic mouse model of HIV-1 (i.e., "Tg26") [17] We did not distinguish between the fast subtypes of MHC isoforms found ... the added benefit of attenuating redox-sensitive mechanisms implicated in cardiac and skeletal muscle derangements [11] Atrogin-1, also known as Muscle Atrophy F-box (MAFbx), and muscle ring finger...

Ngày tải lên: 10/08/2014, 05:21

... The proteolytic rate of skeletal muscle was measured as net release of tyrosine for total protein and 3-MH for myofibrillar protein Compared to the control group, the rate of total protein proteolysis ... the Ub-proteasome system was activated in skeletal muscle under septic conditions The function of the Ub-proteasome system is independent of the amount of protein consumed Consequently, simple ... the Ub system, the release of tyrosine and 3-MH in EDL also decreased These findings, to some extent, suggest that infusion of insulin alleviates degradation of skeletal muscle protein by inhibiting...

Ngày tải lên: 11/08/2014, 06:23

... activation of a number of transcriptional pathways [20,21] Overexpression of PGC-1α in mouse skeletal muscle leads to a proliferation of fatigue-resistant type I muscle fibers [22] Muscle wasting ... accumulation of lipofuscin in skeletal muscle [14], a lipid peroxidation product that may be indicative of mitochondrial damage Similarly, mitochondrial respiratory capacity is attenuated in the hearts of ... substantially decreased in the skeletal muscle of climbers acclimatizing to high altitude [12,13], and was found to be lower in the muscles of Himalayan Sherpas than those of unacclimatized lowlanders...

Ngày tải lên: 11/08/2014, 12:20

... intake of carbohydrate and protein enhanced cycling performance [16,17] and reduced ratings of muscle soreness [14] The ingestion of amino acids before a performance reduced both delayed onset of muscle ... the supplementation of amino acids before and during an ultra-marathon would reduce the increase in the variables of skeletal muscle damage, decrease the subjective feeling of muscle soreness and ... duration of amino acid supplementation and the type of exercise Change in variables of skeletal muscle damage We hypothesized that an amino acid supplementation would lower post-race values of variables...

Ngày tải lên: 11/08/2014, 23:21

... were clearly of metastasis in the right vastustissue window: Soft tissue Contrast enhanced CT, soft medialis/intermedius muscles Figure Contrast enhanced CT, soft tissue window: Soft tissue metastasis ... suffered from a terminal SCC of the tongue with multiple distant metastases which were localized mainly in the peripheral skeletal muscles and adjacent soft tissues of the lower extremities Furthermore, ... the symptoms of acute dyspnoe, orthopnoe and progressive dysphagia The inspection of the oral cavity revealed an extensive lesion of the tongue (Fig 1) with areas of exophytic growth of the tumor...

Ngày tải lên: 12/08/2014, 01:22

... predictors of mortality [4,5] and patients who failed to gain weight after a program of nutritional support also had a worse prognosis [6] Skeletal muscle is a major component of fat free mass and skeletal ... unimportant in the aetiology of muscle weakness or else that they have a synergistic effect with disuse which spares the inspiratory muscles but impacts on muscles of locomotion Page of (page number not ... treatment of patients with COPD: a summary of the ATS/ERS position paper Eur Respir J 2004, 23(6):932-946 Frontera WR, Hughes VA, Fielding RA, Fiatarone MA, Evans WJ, Roubenoff R: Aging of skeletal muscle: ...

Ngày tải lên: 12/08/2014, 15:20