modeling and simulation of tissue load in the human spine

Báo cáo y học: "Large-scale discovery and validation of functional elements in the human genome" ppt

Báo cáo y học: "Large-scale discovery and validation of functional elements in the human genome" ppt

... 312 Bernstein and Kellis polyadenylation signals in the transposon are rejected if they occur early in the coding strand but can be tolerated on the reverse strand Taken together, the four tests ... CpG islands and regions of high sequence conservation at the genome-wide level They are following up on their findings by screening hypersensitive sites in multiple cell types (such as the ones ... state -of- the- art technologies being applied to the identification of functional elements in genomes are producing huge numbers of candidate regions High-throughput assays in human cells and model...

Ngày tải lên: 14/08/2014, 14:21

2 238 0
Statistical methods for the detection and analyses of structural variants in the human genome

Statistical methods for the detection and analyses of structural variants in the human genome

... read may span the breakpoint of the CNV SR analysis has the advantage of being able to pinpoint the location of the breakpoints Assembly-based AS methods, on the other hand, not align the reads to ... CNV1 and CNV2 the same variant?” In 44 Figure 5.1a, when the breakpoints of the two variants match perfectly, there is no doubt in calling them the same variant In Figure 5.1b, the breakpoints ... class, the repeat type (tandem or interspersed), number in the hg19 human genome, percentage of the hg19 human genome covered, and approximate lower and upper bounds for the lengths of the repeat...

Ngày tải lên: 09/09/2015, 10:14

171 568 0
Case Study in Financial Modeling and Simulation of a Forestry Investment potx

Case Study in Financial Modeling and Simulation of a Forestry Investment potx

... Solving the Model 11 Solving the Model 12 Solving the Model Define and predict the long term benefits 13 Solving the Model Define and predict the long term benefits Asses the risks 14 Solving the ... control, fertilizing, pruning and thinning, fire and pest protection  Inflows:wood; commercial thinning, final harvest non-wood; flora gathering, recreation, land renewal  Required rate of return ... the Model Define and predict the long term benefits Asses the risks Estimate the cash flows 15 Solving the Model Define and predict the long term benefits Asses the risks Estimate the cash flows...

Ngày tải lên: 23/03/2014, 04:20

18 786 4
Báo cáo " A numerical model for the simulation of wave dynamics in the surf zone and near coastal structures " pot

Báo cáo " A numerical model for the simulation of wave dynamics in the surf zone and near coastal structures " pot

... determined  from  calibration;  x  and xb  are  respectively  the coordinates  in the on‐ offshore  direction  at  the point  under  consideration and the breaking point;  hm and hmb  are the corresponding mean water depths  ... part  of the lost  wave  energy  is  transformed  into  turbulence  energy.  At  the beginning  of the wave  breaking  process,  the turbulence  is  confined into a small portion of the breaking  ... within  first  five meshes from the lateral boundaries, and then  increases  linearly  with  the distances  from the boundaries towards the ends of the wave absorbing zones. Finally, at the ends of ...

Ngày tải lên: 28/03/2014, 15:20

11 460 0
modeling and simulation of the capacitive acceleration sensor

modeling and simulation of the capacitive acceleration sensor

... Hence, the resonance frequency of the structure can be increased by increasing the spring constant and decreasing the proof mass, while the quality factor of the device can be increased by reducing ... restoring force from the mechanical spring and the dam ping force from the viscous damping The equation o f motion of the p ro o f m ass can be w ritten as: Modeling and simulation o f the capacitive ... rem ains the sam e As show n in Eq 2.19, the output voltage is dependent o f the am plifier gain in the forw ard path and is inversely proportional to the gain in the feedback path Therefore, the...

Ngày tải lên: 25/03/2015, 11:44

87 309 0
Variational methods for modeling and simulation of tool tissue interaction

Variational methods for modeling and simulation of tool tissue interaction

... containing stretching and bending energy and skin tension terms inherent in the anchoring of skin to the underlying layers In order to simulate the impact and wave induced damage in biological tissues ... contains all the remaining internal variables The sub-indices n and n+1 indicate the beginning and ending of the load increment and it is supposed that all quantities at time n are known The potential ... an investigation on statistical modeling of the uncertainties of human artery tissue using probabilistic approach, and characterization of material parameters in human vascular soft tissue during...

Ngày tải lên: 09/09/2015, 11:30

147 388 0
FINITE ELEMENT MODELING AND SIMULATION OF THE GRINDING PROCESS mô HÌNH hóa và mô PHỎNG QUÁ TRÌNH mài BẰNG PHƯƠNG PHÁP PHẦN tử hữu hạn

FINITE ELEMENT MODELING AND SIMULATION OF THE GRINDING PROCESS mô HÌNH hóa và mô PHỎNG QUÁ TRÌNH mài BẰNG PHƯƠNG PHÁP PHẦN tử hữu hạn

... Hence, in order to understand the grinding process, it is important to investigate the grinding mechanism of a single grit grinding In Figure 1, the schematic diagram of single grit grinding is ... grit increases, the magnitude of the equivalent stress in the workpiece increases In contrast with stress distribution in machining, stress in the grinding process spreads in circled bands, rather ... P.Steinmann, K.Weiner, Modelling and simulation of process: machine interaction in grinding, Production Engineering, 2009, Vol 3(1), p 111-120 [10] Opoz, T T., and Chen, X., Single Grit Grinding Simulation...

Ngày tải lên: 08/06/2016, 12:57

8 488 0
A study on cultural obstacles to the teaching and learning of speaking skills in the classroom of grade 10 at nguyen tat thanh high school

A study on cultural obstacles to the teaching and learning of speaking skills in the classroom of grade 10 at nguyen tat thanh high school

... contribution of other factors involved in speaking 1.3 Cultural factors in the teaching and learning of speaking skills in classrooms 1.3.1 What cultural factors influence on the teaching and the learning ... part of learned behavior shared with others The concept include a group’s way of thinking, feeling, and acting, and fixed patterns for doing certain things According to Thompson (1990:132), the ... effectively However, in the thesis, the researcher wants to find out the attitudes, as well as the cultural awareness in teaching and learning spoken English of the teachers and the students of 10 th grade...

Ngày tải lên: 07/09/2013, 13:00

38 1,2K 0
Modeling and Simulation of Microbial Depolymerization Processes of Xenobiotic Polymers

Modeling and Simulation of Microbial Depolymerization Processes of Xenobiotic Polymers

... the class of (M − L)-molecules, respectively The first term of the right-hand side of Eq (12.1) is the total weight loss in the class of M -molecules due to the direct consumption and the β -oxidation, ... -oxidation, and the second term represents the weight conversion from the class of (M + L)-molecules to the class of M molecules due to the β -oxidation 285 286 12 Modeling and Simulation of Microbial ... shows the weight distribution of PLA before and after enzymatic degradation for and 67 h based on the shift according to the baselines shown in Figure 12.10, the transformation according to the...

Ngày tải lên: 25/10/2013, 08:20

26 522 0
Tài liệu Material Usage and Condition of Existing Bridges in the U.S pptx

Tài liệu Material Usage and Condition of Existing Bridges in the U.S pptx

... parallels that of Reference The main purpose for creating and maintaining the NBI is to monitor the condition of bridges carrying public highways Therefore, for funding and reporting purposes, the FHWA ... Bridge Inventory (NBI) as of December 2003 The NBI is maintained by the Federal Highway Administration (FHWA) Tables and figures present information on both the number and deck area of existing ... 20011 The National Bridge Inventory Following the tragic collapse of the Sliver Bridge in December 1967, Congress passed legislation that required each state to inspect and maintain an inventory of...

Ngày tải lên: 20/12/2013, 20:15

29 660 0
Tài liệu CONSUMER PREFERENCE AND CONSUMPTION OF ORGANIC PRODUCTS IN THE EASTERN CAPE PROVINCE OF SOUTH AFRICA docx

Tài liệu CONSUMER PREFERENCE AND CONSUMPTION OF ORGANIC PRODUCTS IN THE EASTERN CAPE PROVINCE OF SOUTH AFRICA docx

... are marked increases in the future demand of all organic products This augurs well for the growth of the organic industry in the Eastern Cape and in South Africa in general The findings of this ... group of people as part of its ways, aids in the cohesion of this group, helps that particular group maintain its identity in the face of others, and therefore creates a feeling of "belonging" ... a long way in influencing the target market and marketing approach to drive the demand of organics The second LDF identified the person responsible for shopping and the location of the consumer...

Ngày tải lên: 14/02/2014, 03:20

28 586 0
Báo cáo khoa học: Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor f chain by the protein tyrosine kinase Lck potx

Báo cáo khoa học: Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor f chain by the protein tyrosine kinase Lck potx

... Role of electrostatic interactions in SH2 domain recognition: salt dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the ... located on the intact protein Therefore, determination of the kinetics of phosphorylation of these peptides allows the order of phosphorylation of the six TCRf ITAM tyrosines, by the PTK Lck, ... groups of peaks at 6.85 and 7.15 p.p.m correspond to the aromatic resonances of the seven tyrosines in the protein, and the inset 2D expansion of the 1H-1H COSY shows that the seven are indistinguishable...

Ngày tải lên: 08/03/2014, 02:20

8 571 0
The impacts of introductions and stocking of exotic species in the Mekong Basin and policies for their control

The impacts of introductions and stocking of exotic species in the Mekong Basin and policies for their control

... The Impacts of Introductions and Stocking of Exotic Species in the Mekong Basin and Policies for Their Control The Impacts of Introductions and Stocking of Exotic Species in the Mekong Basin ... Impacts of Introductions and Stocking of Exotic Species in the Mekong Basin and Policies for Their Control xi The Impacts of Introductions and Stocking of Exotic Species in the Mekong Basin and Policies ... 37 FISOFT/DIAS/INDEX.HTM SHOWING SPECIES INTRODUCED INTO COUNTRIES OF THE MEKONG BASIN vi The Impacts of Introductions and Stocking of Exotic Species in the Mekong Basin and Policies for Their...

Ngày tải lên: 14/03/2014, 08:48

60 465 0
Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot

Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot

... residues for binding the coenzyme The C-terminal domain has a largely a-helical structure, and serves mainly in substrate binding The active site is located in the interdomain cleft, and contains a highly ... reported random binding of NAD+ and Man-ol1P [29] It is reasonable to assume that random binding of reactants by AfM1PDH and AfM2DH occurs in rapid equilibrium, and the absence of curvature in LineweaverBurk ... value of $ 3, indicates that NADH binds to the enzyme prior to binding of Fru6P The absence of a KIE on kcat Km for the substrate binding rst is a clear requirement of the strictly ordered kinetic...

Ngày tải lên: 14/03/2014, 23:20

13 470 0
Environmental Injustice and Human Rights Abuse: The States, MNCs, and Repression of Minority Groups in the World System pptx

Environmental Injustice and Human Rights Abuse: The States, MNCs, and Repression of Minority Groups in the World System pptx

... rain forest, the massacre of Father Nery Lito Satur and several others in the Philippines, and the public hanging of Ken Saro-Wiwa and eight other members of the Movement for the Survival of the ... waste dumping, natural resource exploitation, and the consequent degradation of the means of subsistence of indigenous people The roles of the state and MNCs in suppressing the rights of communal ... policies and official behavior toward the non-core countries Basically, institutionalized discrimination refers to the policies of the dominant institutions in the core and the behavior of individuals...

Ngày tải lên: 15/03/2014, 23:20

21 684 0
Báo cáo khoa học: Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions docx

Báo cáo khoa học: Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions docx

... referring to all of them as caveolae, was demonstrated by their content of both caveolin-1 and caveolin-2 The coexistence of caveolin-1 and caveolin-2 in all three caveolae subclasses is in line ... (Fig 2G), but increased in response to insulin in both the LD-caveolae and HD-caveolae, with the increase being particularly pronounced in the LD-caveolae (Fig 4C) The presence of the triacylglycerol-hydrolysing ... the uptake and hydrolysis of cholesteryl ester from HDL The involvement of SR-B1 in this uptake was indicated by the inhibition of the uptake by the SR-BI inhibitor BLT-1 Conclusions In conclusion,...

Ngày tải lên: 16/03/2014, 13:20

12 460 0
Báo cáo khoa học: Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis potx

Báo cáo khoa học: Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis potx

... important in the literature and have roles assigned [12–18,20]: *, CTP-binding residue of the P-loop; (*), CTP-binding residue; ^, Neu5Ac-binding residue; #, Neu5Ac-binding residue forming part of the ... al [14] in the related enzyme, L-CKS, because mutation would interfere with both Neu5Ac binding as well as playing a role in the re-orientation of Mg2+ binding during the re-opening of the active ... concentrations in the presence or absence of 0.2 mm dithiothreitol Effect of Mg2+ concentration The effect of an increase in the concentration of Mg2+ was determined by measuring the rate of the reaction in...

Ngày tải lên: 22/03/2014, 21:21

12 463 0
Báo cáo khoa học: Human-blind probes and primers for dengue virus identification Exhaustive analysis of subsequences present in the human and 83 dengue genome sequences doc

Báo cáo khoa học: Human-blind probes and primers for dengue virus identification Exhaustive analysis of subsequences present in the human and 83 dengue genome sequences doc

... each serotype of the virus (present in all strains of the serotype), and (d) unique to each individual viral strain’s genome (present in the strain and absent from all other strains) The results ... refer to the sequences that are present in the genome of interest and absent from the host genome as being ‘host-blind’ (human- blind, mosquito-blind, mouseblind, rat-blind, etc.) sequences The greater ... (22-mers) of the viral genome is comprised of n-mers that are not present in any of the other dengue genomes For example, in the genome of the DENV-4 China Guangzhou B5 strain (AF289029), 75.4% of the...

Ngày tải lên: 23/03/2014, 11:20

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