... cities, New York, Philadelphia, and Chicago, consistently fi nished out of the money, while Louisville and St. Louis fi nished in last place for fi ve of eight years. The sorriest situation was in ... G. Spalding of the White Stockings fi ned dissipated players for di- minishing their skills, and hired detectives to watch the most recalcitrant, like Mike “King” Kelly, who along with his outfi ... seasons. The Miracle Braves’ spitballers Bill James and Dick Rudolph combined for 52 wins in 1914, with James winning 19 of his last 20 decisions in the Braves’ incred- ible stretch drive. The Braves’...
Ngày tải lên: 31/03/2014, 10:21
Ngày tải lên: 05/09/2013, 16:10
Tài liệu ADVERTISEMENT NO. 2/2012-13: LAST DATE FOR PAYMENT OF FEE – July 23, 2012 ppt
... Service or on invalidment, Emergency Commissioned Officers or Short Service Commissioned Officers who have completed their initial period of assignment of five years of Military Service but whose ... belonging to categories (ii), (iii), (iv) or (v) above shall be a person in whose favour a certificate of eligibility has been issued by Government of India. The applicant, in whose case a certificate ... inclusive of May 31, 2012) (ii) Applicants must be either (i) a citizen of India, or (ii) a subject of Nepal, or (iii) a subject of Bhutan, or (iv) a Tibetan refugee (who came over to India before...
Ngày tải lên: 16/02/2014, 11:20
Tài liệu Báo cáo khóa học: TbPDE1, a novel class I phosphodiesterase of Trypanosoma brucei pdf
... broad-spectrum PDE inhibitor IBMX, which is widely used in cell biological experimentation, is essentially inactive on TbPDE1, with an IC 50 value of > 1 m M . Discussion This study reports the identification ... considerably improved by growing the cells in TB medium instead of Luria–Bertani medium (see Materials and methods), low activity and high instability remained unsatisfactory. Inclusion of 5 ... amino acids at its C-terminal side. Expression of TbPDE1 in S. cerevisiae The successful complementation screening in yeast indicated that recombinant TbPDE1 is enzymatically active. In addition...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins pptx
... effective inhibition of binding of ICAM-4 positive red cells by anti-ICAM-4 antibodies, indicate a major role for ICAM-4 in binding of red cells to the I domains. The efficient inhibition of the Fig. ... antibody is involved in ICAM-4 binding. Treatment of the coated CD11b I domain fusion protein with I domain specific anti-CD11b antibodies resulted in an efficient inhibition of the adherence of ... their ability to inhibit in solid phase assay. MEM170, 44a and 107 were highly active inhibitors of the CD11b I domain GST interaction with ICAM 4, whereas LM2/1 inhibited weakly but significantly...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot
... the similarity of the t wo fasciclin domains in CLAP with other fasciclin I containing proteins is clear (Fig. 9). Using BLAST (http://www.ncbi.nlm.nih.gov/BLAST) to identify related proteins, ... cell adhesion protein in Artemia (Eur. J. Biochem. 271) 4017 Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS -I family of cell adhesion proteins Alden ... preincubation at 40 °C and pH 6.8, whereas the dimer retained about 70% of its initial activity under these conditions (Fig. 4C). Similar differences in cathepsin L activity were observed at a ll incubation...
Ngày tải lên: 07/03/2014, 16:20
Recombinant DNA I - Basics of molecular cloning Polymerase chain reaction cDNA clones and screening
... becomes available, the uses of PCR expand. • With appropriate primers, one can amplify the desired region from even miniscule amounts of DNA. • Not limited by the distribution of restriction endonuclease ... positive selection for recombinants. Not to scale. Introduction of recombinant DNA into living cells via vectors • Autonomously replicating DNA molecules – (have an origin of replication) • Selectable ... procedures to isolate a gene that represents as little as 1 part in a million of the genetic material in an organism. • DNA from the organism of interest is divided into small pieces that are...
Ngày tải lên: 13/03/2014, 18:39
AMERICAN CONSTITUTIONAL LAW VOLUME I SOURCES OF POWER AND RESTRAINT pptx
... justices in the majority for their suggestions and, ultimately, their signatures. A draft opinion that fails to receive the approval of a majority of jus- tices participating in a given decision ... justice in 1801, is generally cred- ited with instituting the practice of issuing an Opinion of the Court, which reflects the views of at least a majority of the justices. It appears that this ... Doctrine of Abstention Closely akin to exhaustion of remedies is the doctrine of abstention. Whereas the principal application of the exhaustion of remedies doctrine is to bureaucratic deci- sion...
Ngày tải lên: 16/03/2014, 03:20
Báo cáo khoa học: Photosynthetic acclimation: Structural reorganisation of light harvesting antenna – role of redox-dependent phosphorylation of major and minor chlorophyll a/b binding proteins pot
... protein in higher plants [71,72], could regulate dynamic redistribution of LHCII from PSII to PSI during state transitions by providing a linker domain for binding LHCII trimers. The Arabidopsis ... dissociation of the LHCII–PSII super- complex and diffusion of the mobile LHCII pool. Understanding the precise regulation of this process, in particular identification of the specific kinases and their ... compilation ª 2008 FEBS 1063 Specificity of state transitions in C. reinhardtii Chlamydomonas reinhardtii provides a unique system for analysis of the mechanism of state transitions, in particular,...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot
... significant differences in the expression of antioxidant genes in cells with mitochondrial dysfunction [44,45]. Participation of transcription factors in the antioxidant defense of cells with ... dehydrogenase, mitochondrial isocitrate de- hydrogenase, glutathione peroxidase III, heat shock protein 104, thioredoxin peroxidase II, catalase A, nuc- lear thioredoxin peroxidase, thioredoxin I and glutare- doxin ... transcription factor whose activation might be influenced by cTPxI. It is worth noting the influence of the functional state of mitochondria in the H 2 O 2 -induced expression levels of various genes,...
Ngày tải lên: 16/03/2014, 14:20
PROGRESS IN FINANCIAL SERVICES RISK MANAGEMENT: A SURVEY OF MAJOR FINANCIAL INSTITUTIONS pdf
... scenario analysis around liquidity Creating a global single-point liquidity management Implementing a dedicated liquidity risk management function Building a dedicated liquidity risk data ... shift post-crisis (see Exhibit 26). 7 When asked to discuss their areas of responsibility and committee participation, most CROs described wide-ranging responsibilities and involvement in ... business imperatives and the Basel III regime. About a third (30%) of respondents indicated they are exiting or selling portions of their businesses to reduce the impact of the new liquidity...
Ngày tải lên: 22/03/2014, 21:20
Báo cáo khoa học: Lack of stabilized microtubules as a result of the absence of major maps in CAD cells does not preclude neurite formation pot
... antigen transgenic mice. J Neurosci 13, 1280–1291. 27 Qi Y, Wang JK, McMillian M & Chikaraishi DM (1997) Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated ... October 2009) doi:10.1111/j.1742-4658.2009.07422.x In many laboratories, the requirement of microtubule-associated proteins (MAPs) and the stabilization of microtubules for the elongation of neurites has been intensively investigated, with ... are visualized after 24–48 h. In all experiments, the differen- tiation status of cells was confirmed by microscopic exami- nation. Antibodies Rabbit polyclonal antibodies specific to Glu-tubulin...
Ngày tải lên: 23/03/2014, 05:22
The Integration of Major League Baseball potx
... most of the other top candidates were still in the service was of no small consideration. It’s particularly ironic that Robinson’s difficul- ties with white authority in the military helped him rise ... pursue integration. With the end of World War II already in sight, the death of Commissioner Kenesaw Mountain Landis in November 1944 gave Rickey the freedom to begin putting his plan into action. ... managing to denigrate three minority groups in one sitting with the threat, “If McGraw keeps this ‘Indian’ I will put a Chinaman on third base. This Cherokee is really Grant fixed up with war paint...
Ngày tải lên: 23/03/2014, 22:20
Charles I Makers of History docx
... dismissed from the king's service. The king, instead of dismissing him, took measures to have him appointed, in addition to all his other offices, Chancellor of the University of Cambridge, a very ... with these feelings, and the chief point of interest in the history of his reign is the contest in which he engaged with the English people in his attempts to maintain them. The body with which ... in their speeches. It is the theory of the British Constitution that the king can do no wrong; whatever criminality at any time attaches to the acts of his administration, belongs to his advisers,...
Ngày tải lên: 23/03/2014, 23:20
[TO BE PUBLISHED IN THE GAZETTE OF INDIA, EXTRAORDINARY PART-II, SECTION-3, SUB-SECTION (i)] - MINISTRY OF CORPORATE AFFAIRS potx
... or (viii) preserving or storing any product in cold storage; or (ix) constructing, reconstructing, reconditioning, repairing, servicing, refitting, finishing or demolishing of buildings or ... delivery or disposal; or (iii) constructing, reconstructing, reconditioning, servicing, refitting, repairing, finishing or breaking up of any products. (k) “Mining Activity” includes any ... any mode or medium; or (xii) obtaining, compiling, recording, maintaining, transmitting, holding or using the information or data or knowledge; or (xiii) executing instructions in memory to...
Ngày tải lên: 29/03/2014, 14:20