introduction and general view of the biosynthetic pathway

Báo cáo khoa học: A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration doc

Báo cáo khoa học: A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration doc

... throughout the body of the cell, and the substrate at the basal surface of the ECs Interestingly, forces acting at one surface may be propagated internally or even to other surfaces of the cell, or they ... Activation of the NF-jB pathway leads to recruitment and activation of IjB kinase kinase; the phosphorylation and activation of IjB kinase by IjB kinase kinase; the phosphorylation of IjB; and the degradation ... the ECs In (A), the force acting on the EC (black arrow) has components both in the direction of shear stress and in the direction of pulling by leukocytes In (B), the force on the EC is in the...

Ngày tải lên: 22/03/2014, 21:20

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Investigating the Biosynthetic Pathway of Polyacetylenic Natural Products in Fistulina hepatica and Echinacea purpurea

Investigating the Biosynthetic Pathway of Polyacetylenic Natural Products in Fistulina hepatica and Echinacea purpurea

... acid   pathway,   the   stearolic   acid   pathway, and the  tariric  acid pathway    These  pathways  differ  from  one  another  based   on the  regioselectivities of  desaturation and/ or ... Integrity and Copyright Disclaimer Title of Thesis/Dissertation: Investigating the Biosynthetic Pathway of Polyacetylenic Natural Products in Fistulina hepatica and Echinacea purpurea For the degree of ...   whether  a general  mechanism  is  involved  in the  biosynthesis of  these  molecules   This  thesis  investigates the  dehydrogenation  pathways  involved  in the  formation   of  ...

Ngày tải lên: 24/08/2014, 11:28

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Tài liệu A Short View of the Frauds and Abuses Committed by Apothecaries, by Christopher Merrett pptx

Tài liệu A Short View of the Frauds and Abuses Committed by Apothecaries, by Christopher Merrett pptx

... they have two Supervisors set over them more then any Company that I know of, viz the Censors of the College of Physicians, and the Master and Wardens of their own Company The next thing is the ... upon the Simples, and Compounds of the Shops So that the Customer can tell the price of what he hath occasion to use, and not stand at the mercy of the Apothecary to rate them as he lists, and ... confess The said Charter prays for the publick good only (there being the same reason of all) they might have the same power of Surveying them also, as they have of the Apothecaries, which most of the...

Ngày tải lên: 17/02/2014, 07:20

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A SYSTEM OF LOGIC, RATIOCINATIVE AND INDUCTIVE, BEING A CONNECTED VIEW OF THE PRINCIPLES OF EVIDENCE, AND THE METHODS OF SCIENTIFIC INVESTIGATION pdf

A SYSTEM OF LOGIC, RATIOCINATIVE AND INDUCTIVE, BEING A CONNECTED VIEW OF THE PRINCIPLES OF EVIDENCE, AND THE METHODS OF SCIENTIFIC INVESTIGATION pdf

... XII Of The Explanation Of Laws Of Nature  Chapter XIII Miscellaneous Examples Of The Explanation Of Laws Of Nature  Chapter XIV Of The Limits To The Explanation Of Laws Of Nature; And Of Hypotheses ... occupations The business of the magistrate, of the military commander, of the navigator, of the physician, of the agriculturist, is merely to judge of evidence, and to act accordingly They all have ... at the mouth of the Dart But it is no part of the signification of the word John, that the father of the person so called bore the same name; nor even of the word Dartmouth, to be situated at the...

Ngày tải lên: 06/03/2014, 13:20

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Strategic Marketing and the Resource Based View of the Firm pptx

Strategic Marketing and the Resource Based View of the Firm pptx

... Fahy, Smithee / Strategic Marketing and the Resource Based View of the Firm Strategic Marketing and the Resource Based View of the Firm Discourse in the field of strategic marketing ... integrated review of the origins, insights and status of the resource-based view of the firm As Collis (1991) notes, no coherent body of theory has as yet emerged to summarise the resource-based view ... VIEW Over the past decade or so, there have been a large and diverse collection of contributions in the areas of economics and strategic management that seek to either refine the concept of the...

Ngày tải lên: 15/03/2014, 22:20

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The special and general theory of relativity   a  einstein

The special and general theory of relativity a einstein

... Behaviour of Measuring-Rods and Clocks in Motion Theorem of the Addition of Velocities The Experiment of Fizeau The Heuristic Value of the Theory of Relativity General Results of the Theory Experience ... years later by the Theory of the Specific Heat of Solid Bodies, and the fundamental idea of the General Theory of Relativity During the interval 1909 to 1911 he occupied the post of Professor Extraordinarius ... of the rod and the end of the rod lie with respect to K at a particular time t of the system K By means of the first equation of the Lorentz transformation the values of these two points at the...

Ngày tải lên: 17/03/2014, 14:28

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Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc

Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc

... roles of the various members of the DIM family, e.g DIM A and DIM B, in these functions have never been investigated The recent developments in our understanding of the biosynthetic pathway of DIMs ... the complex biosynthetic pathways of DIMs and PGLs These efforts have led to the identification of more than 20 proteins required either for the formation or for the translocation of these compounds ... i.e DIMs and PGL-tb; and (b) to address the question of the function of the two related molecules DIM A and DIM B According to the accepted model of DIM and PGL biosynthesis [17], DIM A and PGL-tb...

Ngày tải lên: 23/03/2014, 09:20

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Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot

Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot

... quantitative analysis of the most critical parameters of the pathway regarding this goal requires the knowledge of the intracellular concentrations of all metabolites involved and a kinetic model ... minimization of the difference between experimental time course data and the corresponding values predicted by the solution of the differential equations derived from a mathematical model of the kinetic ... extreme modulations of enzyme activities In particular, in the combinations involving the decrease of glyoxalase II activity the effect is equivalent to the modulation of the other parameters alone,...

Ngày tải lên: 23/03/2014, 13:20

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Báo cáo khoa học: Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation potx

Báo cáo khoa học: Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation potx

... depend on the trigger type and on the level of interference with the Wnt pathway We conclude that the type of the trigger and the regulation level within the Wnt pathway decide about the gene ... cells We conclude from these findings that the activating trigger and the level of activation within the pathway are crucial for the selection of a target gene and the trend of the promoter regulation ... the right sides of the gels these of the two other isoforms (Fig 6) These results correlate to the protein bands of  38 kDa (Plf1) and 27 kDa (Mrp4) [27], which were detected in the western blot...

Ngày tải lên: 30/03/2014, 16:20

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Báo cáo khoa học: Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan Glycoengineering for enhanced cell binding and serum clearance of the neoglycoprotein pot

Báo cáo khoa học: Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan Glycoengineering for enhanced cell binding and serum clearance of the neoglycoprotein pot

... [19], and therefore the presence of this substitution in the LEC14 epitope, must not be neglected The ensuing comparison between the properties of the LEC14 dodecasaccharide epitope and the core-fucosylated ... (see inset) values These results confirm a striking effect of receptor topology at constant spatial features of the ligand They also enable us to set the ligand properties of the extended LEC14 ... resistance, and contributes to the complex changes in the glycoproteomic profile of the LEC14 mutant vs wild-type cells [18] The enzymatic introduction of the b1,2-linked GlcNAc moiety into the biantennary...

Ngày tải lên: 30/03/2014, 16:20

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báo cáo hóa học: " Factor structure and internal consistency of the 12-item General Health Questionnaire (GHQ-12) and the Subjective Vitality Scale (VS), and the relationship between them: a study from France" potx

báo cáo hóa học: " Factor structure and internal consistency of the 12-item General Health Questionnaire (GHQ-12) and the Subjective Vitality Scale (VS), and the relationship between them: a study from France" potx

... population of France MSY was the main investigator and analysed the data and wrote the first draft AI and CR contributed to the study design and the analysis AM contributed to the analysis and wrote the ... available, including the GHQ-30, the GHQ-28, the GHQ-20 and the GHQ-12 The shortest version of the questionnaire (GHQ-12) has been extensively validated and used in a number of countries and in different ... coefficient and was found to be 0.83, well above the threshold for a satisfactory value Relationship between the GHQ-12 and the VS The correlation between the GHQ-12 and the VS scores was investigated and...

Ngày tải lên: 18/06/2014, 19:20

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Báo cáo y học: "The role of the Notch pathway in healthy and osteoarthritic articular cartilage: from experimental models to ex vivo studies" pdf

Báo cáo y học: "The role of the Notch pathway in healthy and osteoarthritic articular cartilage: from experimental models to ex vivo studies" pdf

... reported expression of Notch family members in adult and even OA cartilage raised the issue of the involvement of this pathway in the physiopathology of OA and especially in the changes that chondrocytes ... 1, and These constitute the DSL (Delta/Serrate/Lag2) family (Figure 1) Activation of the Notch pathway The first described Notch activation cascade consists of a series of cleavages leading to the ... disease and the degradation of the articular cartilage is a complex process involving several actors, including signaling pathways like the Notch pathway Further work is required to understand the...

Ngày tải lên: 12/08/2014, 15:22

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Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway" pot

Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway" pot

... stimuli [11-13] However, in spite of the relevance of these reservoir cells in the control of viral persistence, the mechanisms responsible of apoptosis resistance of persistently-infected cells ... independent of the magnitude of viral replication Apoptosis resistance is independent of the magnitude of viral replication A) Jurkat and J1.1 cells were incubated in the presence or absence of 1000 ... modulation of the mitochondrial pathway by regulating Bax pore induction Further experiments are needed in order to clarify the mechanism by which the virus decreases MMP and controls the execution of...

Ngày tải lên: 13/08/2014, 06:20

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Báo cáo y học: " A heuristic approach and heretic view on the technical issues and pitfalls in the management of penetrating abdominal injuries" pdf

Báo cáo y học: " A heuristic approach and heretic view on the technical issues and pitfalls in the management of penetrating abdominal injuries" pdf

... palpate the aorta posterior to the pancreas and fully visualize the anterior and posterior aspects of the second and third part of the duodenum, as well as the head and uncinate process of the pancreas ... been passed through the spleen, in the lumen of the needle in opposite direction-from the tip of the needle to the bevel Remove the needle and tie the two ends of the thread and you have your first ... lacerated IVC, the edges of the defect contract, due to the elastic fibers of the wall, making the identification and the exact grasping of the edges with the Babcocks difficult Furthermore, the application...

Ngày tải lên: 13/08/2014, 23:20

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DEPRESSIVE SYMPTOMS AND RELATED FACTORS OF THE GENERAL MEDICAL STUDENT AT HAI PHONG UNIVERSITY OF MEDICINE AND PHARMACY IN 2016

DEPRESSIVE SYMPTOMS AND RELATED FACTORS OF THE GENERAL MEDICAL STUDENT AT HAI PHONG UNIVERSITY OF MEDICINE AND PHARMACY IN 2016

... live in the hostels, the number of students1st grade are the highest percentage of 90,1%, followed by the 3rd and the 2nd grade Moreover, the living rate at the hostel of the 4th, the 5th, the 6th ... their studying result All of them cause stress and depression However, the influence of these factors depends on the individual's personality The insensitivity of medical students: Although the ... Among of them, the 6th grade is the highest (98,7%), followed to the 2nd grade is 96%, next are the 5th, 4th, 1st grade with the percentage of 88%, 87,7%, 85,9% , respectively and the lowest is the...

Ngày tải lên: 09/06/2016, 22:40

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Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.

Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.

... mentioned The men, especially the husband and the grandfather, sip alcohol and tell their family members what they see and hear or remind them of right or wrong things in life The others also ... denoting the objects covered by the scope of the notion expressed in the word, and the significative function is the function of expressing the content of the respective notion The function of rendering ... difficult The oldest or the husband of the family sits at the head of the table and others sit in descending order according to age or wherever they like The meal starts when everyone has their own...

Ngày tải lên: 15/04/2013, 15:11

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A View of the History of Biochemical Engineering

A View of the History of Biochemical Engineering

... renewed interest in the conversion of biomass into fuels and chemicals In 1978, the first of a series of conferences on Biotechnology for Fuels and Chemicals A View of The History of Biochemical Engineering ... of engineering research and development work over the years In the late 1960s and early 1970s, there was a worldwide perception of the possible shortage of food to feed the world population The ... pharmaceutical companies worldwide in the 1950s and 1960s There was a strong demand for better designs of aeration systems and deeper understanding of the process of oxygen transfer in biological...

Ngày tải lên: 23/10/2013, 17:20

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