implications for drug craving and relapse

drug abuse handbook

drug abuse handbook

... duplicate names (chlorotestosterone and Clostebol; dihydrotestosterone and stanolone; and methandrostenolone and methandienone) as well as one name (methandranone) for a drug that did not exist So, the ... Alcohol Ingestion Anders Helander and Alan Wayne Jones Neurochemistry of Drug Abuse Edited by Deborah C Mash and Julie K Staley 6.1 The Dopamine Transporter and Addiction John W Boja and William M ... Baenziger 10.3 Analytical Considerations and Approaches for Drugs Michael Peat and Alan E Davis 10.4 Urine Specimen Suitability for Drug Testing Ruth E Winecker and Bruce A Goldberger 10.5 The Role...

Ngày tải lên: 11/04/2014, 02:17

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Responsible Research with Biological Select Agents and Toxins potx

Responsible Research with Biological Select Agents and Toxins potx

... individuals watch out for each other and take responsibility for both their own performance and that of others When this works well, the environment and culture reinforce a positive and inclusive ethic ... knowledge, tools, and techniques resulting from research would be used for malevolent purposes The BMBL and this report use the term to cover security for both pathogens and for the information that ... provide “recommendations for any new legislation, regulations, guidance, or practices for security and personnel assurance for all Federal and nonfederal facilities … and options for establishing oversight...

Ngày tải lên: 15/03/2014, 15:20

189 458 0
Business Change - The Roles of Change Agents and Subject Matter Experts in Organization Change potx

Business Change - The Roles of Change Agents and Subject Matter Experts in Organization Change potx

... world with coaching and training with outstanding results Here are some examples for you A senior executive who needed all the information before making a decision therefore holding up the workflow ... on-time delivery performance, and the formal monitoring of customer satisfaction data and trends Also, improvement plans will be needed to ensure continual improvement Understanding and embracing these ... my enthusiasm for my work and had broken regulations The job I had created for myself, by showing enthusiasm and creativity had begun as a menial fetching and carrying assignment for physiotherapists...

Ngày tải lên: 28/06/2014, 17:20

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Chương 11: Modeling System Agents and Responsibilities pps

Chương 11: Modeling System Agents and Responsibilities pps

... MeasuredSpeed MeasuredLoc Control CommandedSpeed CommandedAccel Send Command Monitoring Command Performance Chap.11: Modeling System Agents © 2009 John Wiley and Sons 20 Alternative agent assignments ... Controller Command CommandedAcceleration Chap.11: Modeling System Agents © 2009 John Wiley and Sons 24 A dependency diagram shows agents and their dependencies  Dependencies among agent pairs for goals ... believes F and F actually holds  Optional agent feature used for – obstacle analysis: wrong belief obstacles are common ag believes F and F does not hold e.g BeliefParticipant (m.Date = d) and m.Date...

Ngày tải lên: 13/07/2014, 07:20

36 352 0
Báo cáo y học: " Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis: a pilot study" pptx

Báo cáo y học: " Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis: a pilot study" pptx

... Switzerland); total cholesterol, HDLcholesterol, and triglycerides (Olympus Diagnostics, County Clare, Ireland); LDL-cholesterol (Randox Laboratories Ltd, Crumlin, UK); and plasma glucose and serum ... (µU mmol/ml l) for identification of insulin resistance and a threshold QUICKI value of 0.337 for identification of decreased insulin sensitivity Materials and method Patients and investigations ... interassay coefficients of variance for CRP were 0.43% and 1.34%, respectively; those for insulin were 1.9% and 1.2%, respectively Disease-modifying antirheumatic drug treatment At enrolment, we...

Ngày tải lên: 09/08/2014, 06:22

7 365 0
báo cáo khoa học: "Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights" doc

báo cáo khoa học: "Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights" doc

... receive amonafide and Ara-C Overall CR + CRi rate was 42% CR rates among age

Ngày tải lên: 10/08/2014, 22:21

10 252 0
using cognitively inspired agents and information supply chains to anticipate and share information for decision making teams(fileminimizer)

using cognitively inspired agents and information supply chains to anticipate and share information for decision making teams(fileminimizer)

... decision process models for identifying information needs and (2) how to design information systems for coordinating information request and delivery so that those needs are met Therefore, this survey ... anticipation of information needs Not designed for anticipating information needs and information management Inadequate for efficient information sharing when capacities are limited Not used for coordinating ... information and the needed information for supporting decision-making A peak in the timeline of the available information may represent a situation of information overload or too much noisy information;...

Ngày tải lên: 13/11/2014, 11:12

290 266 0
Buffers, buffering agents, and ionic equilibria

Buffers, buffering agents, and ionic equilibria

... optimal pH value for the formulation Knowledge of the pH stability profile of a drug substance enables one to deduce the pH range for which formulation is desirable, and the basis for the most appropriate ... phosphate, citrate, and acetate are most commonly used for such purposes.[7,8] Ethanolamine and diethanolamine are also used to adjust pH and form their corresponding salts, whereas lysine and glycine ... buffer protein and peptide formulations Akers[9] has reviewed the scope of drug excipient interactions in parenteral formulations and has provided an overview of the effect of buffers on drug substance...

Ngày tải lên: 14/04/2015, 13:46

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Development and applications of novel solvent minimized techniques in the determination of chemical warfare agents and their degradation products

Development and applications of novel solvent minimized techniques in the determination of chemical warfare agents and their degradation products

... cause nausea and vomiting and can also induce cough, headache, and nose and throat irritation The vomiting agents are typically solids which when heated, vaporize and condense to form aerosols ... MIP is formed by cross-linking styrene with divinylbenzene and templated for PMPA for the detection of PMPA and isopropyl methylphosphonic acid (IMPA), the hydrolysis products of Soman and Sarin ... Netherlands, to achieve the object and purpose of the Convention, to ensure the implementation of its provisions, including those for international verification of compliance with it, and to form...

Ngày tải lên: 14/09/2015, 14:08

189 490 1
Exploration of the functional significance of mig 2 in human cancer cell susceptibility to cytotoxic agents and cell growth control a pilot study

Exploration of the functional significance of mig 2 in human cancer cell susceptibility to cytotoxic agents and cell growth control a pilot study

... buffer PB and centrifuge for 30-60 sec and discard the flow-through Wash again with 0.75 ml of buffer PE and centrifuge for 30-60 sec Discard the flow-through and centrifuge again for Transfer ... drug- target interaction is modified These mechanisms, basically regarded as upstream events, include: transporting drug into cells, drug activations, interactions between drugs and targets, and ... anticancer drugs and to observe the effect of mig-2 on cell behavior Both transient and stable transfections were performed to examine the role of mig-2 in anticancer drug resistance and in other...

Ngày tải lên: 05/10/2015, 22:15

123 257 0
Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain

Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain

... barrier and finding alternative routs for drug delivery Drug manipulation includes lipophilic analogs [28], prodrugs [29-31], chemical drug delivery [32, 33], carrier-mediated drug delivery [34], and ... the drug Secondly, it can reduce toxicity of the cancer drug and side effects of drug adjuvant [93] Thirdly, it can provide a sustained and effective drug level by controlled release of the drug ... a variety of drugs including neurotransmitter, antibiotics, and antineoplastic agents Carrier mediated drug delivery Controls the delivery and retention of drugs, e.g., Levodopa and melphalin...

Ngày tải lên: 26/11/2015, 22:48

93 258 0
Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

... for hSGLT1 and 10 µM for hSGLT2, while thioglycoside VII showed IC50 values of 15 µM for hSGLT1 and 88 µM for hSGLT2 These data confirm the strong inhibitory effects of thioglycoside I and VII on ... µM for hSGLT1 and from 10 µM to 88 µM for hSGLT2 The values obtained by the thioglycosides were similar to those obtained with phlorizin, which were equivalent to 42 µM and 28 µM for hSGLT1 and ... [(A460/A580)/(I460/I580)], where A and I represent the readings after or before addition each thioglucoside, respectively For I, the readings Int J Med Sci 2007, from 2-5 sec were averaged; and for A, readings...

Ngày tải lên: 26/10/2012, 10:04

9 651 0
Tài liệu ALPHABETICAL INDEX OF REPRESENTED ORGANIZATIONS AND THEIR LEGISLATIVE AGENTS BY REGISTRATION NUMBER FOR THE THIRD QUARTER 2002 docx

Tài liệu ALPHABETICAL INDEX OF REPRESENTED ORGANIZATIONS AND THEIR LEGISLATIVE AGENTS BY REGISTRATION NUMBER FOR THE THIRD QUARTER 2002 docx

... 1247 Coalition for Affordable Housing and the Environment 483 Coalition for Affordable Housing and the Environment 1160 Coalition for Auto Insurance Competition 365 Coalition for Natural Health ... Cendant Corp 551 Cendant Corp 1224 Center for Energy & Economic Development The 1077 Center for Family Guidance 868 Center for International Education 1244 Center for Non-Profit Corp Inc 682 Central ... REPRESENTED ORGANIZATIONS AND THEIR LEGISLATIVE AGENTS BY REGISTRATION NUMBER FOR THE THIRD QUARTER 2002 CLIENT ORGANIZATION NAME AGENT REGISTRATION NUMBER Forbes Inc 360 Ford Motor Co 1187 Foster...

Ngày tải lên: 16/02/2014, 10:20

51 574 0
Tài liệu Báo cáo khoa học: Mammalian mitotic centromere-associated kinesin (MCAK) A new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents pptx

Tài liệu Báo cáo khoa học: Mammalian mitotic centromere-associated kinesin (MCAK) A new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents pptx

... at 24 °C for 30 min, and then centrifuged at 223 000 g for 15 For the assay shown in Fig 6B, there was 2% (final concentration) DMSO in all samples Supernatants and pellets were assayed for the ... overexpressed, purified for SPR analysis, and an in vitro MT depolymerization assay was conducted Protein expression was performed by transforming the construct into BL21 (DE3)-pLysS (Novagen) and growing ... stabilized microtubles, SQAGs, and reaction components were mixed, and then were incubated at 24 °C for 30 The reaction mixture was centrifuged at 223 000 g and the supernatant and the pellet were separated...

Ngày tải lên: 19/02/2014, 17:20

9 891 0
SECURITIES MARKETS AND THEIR AGENTS: SITUATION AND OUTLOOK docx

SECURITIES MARKETS AND THEIR AGENTS: SITUATION AND OUTLOOK docx

... Balanced equity and balanced international equity Includes: Euro equity and international equity Europe, Japan, United States, emerging markets and others Annual return for 2006 and 2007 and non annualised ... processing and execution Distribution and underwriting Securities custody and administration Portfolio management Design and advising Search and placement Margin trading Fund subscriptions and redemptions ... billion, breaking down 60% for the banks, 14% for other financial companies, 13% for non-financial companies and 5% for the savings banks One salient development in both VCFs and VCCs is the dwindling...

Ngày tải lên: 06/03/2014, 10:20

46 247 0
Báo cáo khoa học: The bI/bIII-tubulin isoforms and their complexes with antimitotic agents pptx

Báo cáo khoa học: The bI/bIII-tubulin isoforms and their complexes with antimitotic agents pptx

... with small ligands and ⁄ or other proteins, and some by modeling No structure determination is available for the human proteins and therefore we needed to build comparative models for the human ... Free energy, enthalpy and entropy for the drug- protein complexes computed at 300 K P1 and P3 refer to paclitaxel bound to human b-tubulin isoforms I and III, respectively I1 and I3 to IDN5390 bound ... of paclitaxel for the bI isoform than for the bIII isoform, and an opposite behavior of IDN5390 3304 Fig Paclitaxel in complex with (A) bI-tubulin (P1), and (B) bIIItubulin (P3) For sake of clarity,...

Ngày tải lên: 16/03/2014, 13:20

10 454 0
TALENT AGENTS, PERSONAL MANAGERS, AND THEIR CONFLICTS IN THE NEW HOLLYWOOD docx

TALENT AGENTS, PERSONAL MANAGERS, AND THEIR CONFLICTS IN THE NEW HOLLYWOOD docx

... changed in recent years, and that change has blurred the traditional distinction between agents and managers Today, it is typical for managers to procure employment and for agents to act as producers ... the California Legislature and the industry guilds have established role-specific rules that restrict what agents and managers can A STATE LAW The California Legislature regulates agents and managers ... appropriate standards for agents who represent guild members in individual negotiations 80 The mechanism through which the guilds have enforced these standards is a mutual understanding among...

Ngày tải lên: 16/03/2014, 17:20

24 714 0
Adaptive Narrative: How Autonomous Agents, Hollywood, and Multiprocessing Operating Systems Can Live Happily Ever After docx

Adaptive Narrative: How Autonomous Agents, Hollywood, and Multiprocessing Operating Systems Can Live Happily Ever After docx

... enough for his baby son to eat that night While the lieutenant can “swap” foreground and background narratives, in same way as the fg and bg console commands can swap UNIX foreground and background ... arrogance; and, (e) a deteriorating situation at base command, where demands on men and equipment may mean a shortage of relief troops, ground vehicles, and helicopters On their own, the Swapping foreground ... Michael van Lent for their assistance in clarifying and formalizing many of the concepts in this paper, and for their patience in reviewing and commenting on the manuscript References Swartout,...

Ngày tải lên: 16/03/2014, 17:20

10 486 0
Báo cáo " Pattern and determinant agents of the debris and mud flash flood in Lay Nua Commune area, the Former Muong Lay District, Dien Bien Province " docx

Báo cáo " Pattern and determinant agents of the debris and mud flash flood in Lay Nua Commune area, the Former Muong Lay District, Dien Bien Province " docx

... squeesed,  crushed  and broken  taking  the  imbrications  and leaflike  polish  structure  (eg.  black  clay  shales  and silty  sandstone  of  the  Lai  Chau  Formation)  and the  valley  ... making here a big trapezium ‐ shaped meander  (Fig. 1 and 2): on the one hand because of high  level  of  tectonic  fissuration,  on  the  other  hand  owing to the presence of the erodible shales and silty  sandstone  ... Tableland  [1],  belong  to  a  group  of  lithological,  structural  and geomorphological  agents  and can  be  used  as  the  credible  and effective  indicators  for warning  the  debris  and ...

Ngày tải lên: 22/03/2014, 12:20

10 306 0
ALPHABETICAL INDEX OF REPRESENTED ORGANIZATIONS AND THEIR GOVERNMENTAL AFFAIRS AGENTS BY REGISTRATION NUMBER FOR THE SECOND QUARTER 2005 potx

ALPHABETICAL INDEX OF REPRESENTED ORGANIZATIONS AND THEIR GOVERNMENTAL AFFAIRS AGENTS BY REGISTRATION NUMBER FOR THE SECOND QUARTER 2005 potx

... Coalition for Affordable Housing & the Environment 483 Coalition for Affordable Housing & the Environment 1402 Coalition for Brain Injury Research 365 Coalition for Natural Health 1192 Coalition for ... Trenton Cos 1230 Flavor & Extract Manufacturers Assn 841 Forbes Inc 360 Ford Motor Co 1187 Foreign Language Educators of New Jersey 1310 Former Trooper Assn 868 Foster Wheeler Corp 75 Foundation ... ORGANIZATIONS AND THEIR GOVERNMENTAL AFFAIRS AGENTS BY REGISTRATION NUMBER FOR THE SECOND QUARTER 2005 CLIENT ORGANIZATION NAME AGENT REGISTRATION NUMBER Assist America Inc 26 Assn for Children...

Ngày tải lên: 22/03/2014, 21:20

75 401 0
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