implications for antigen presentation

... B The table also shows the values for bound (holoform) and unbound (apo-form) cases separately L55–H57 ˚ distance (A) Total dataset (100) Holo-form (70) Apo-form (30) Cluster Cluster Cluster ... (2002) Introduction to Bioinformatics Oxford University Press, Oxford, New York 2866 36 Pintar A, Carugo O & Pongor S (2003) DPX: for the analysis of the protein core Bioinformatics 19, 313–314 37 ... clearly relevant for antibody and antibody library design, but also for humanization experiments The type B interface is only found in the mouse, and therefore grafting the antigen- binding site...

Ngày tải lên: 28/03/2014, 22:20

... with the indicated surface antibodies for phenotypic analysis by flow cytometry Each experimental condition (seven for A549 cell line and five for AECII) was performed in triplicate, the mean value ... mouse model [35] Therefore, we suggest that both CD58 and CD54 could play a major role in the antigenic presentation by AECII and that these cells could be able to present antigens to both CD4+ ... http://respiratory-research.com/content/12/1/15 Many studies turned therefore to a better characterization of the AECII phenotype and more precisely on the detection of surface molecules involved in antigenic presentation As T-cell receptor...

Ngày tải lên: 12/08/2014, 13:22

... reencountering an antigen This also implies that mainly antigen- experienced T cells express surface CTLA-4 and are probably regulated by it [17–19] This fact is of particular interest for already established ... cytokine genes, for example IL-2 and interferon-γ [21], as well as the expression of G1-kinases, a prerequisite for cell cycling In addition, the induction of IL-2 leads to autocrine support for the ... CD4+ T cells [25], but enhanced surface staining for CTLA-4 performed on naive T cells did not detect CTLA-4 protein [11] The surface CTLA-4 is therefore expressed at very low concentrations (fewer...

Ngày tải lên: 09/08/2014, 01:23

... was used to collect data for all the three types of services: a fastfood restaurant for pure service, an airline for mixed service, and a longdistance telephone company for quasi-manufacturing ... customers SERVQUAL, an instrument for measuring service quality was developed on the basis of the above five dimensions SERVQUAL has been gaining acceptance as a platform for work in service quality ... of the reasons for the importance of service quality are: q The economy of the USA and other western nations has become a service economy For example, in the USA service accounts for approximately...

Ngày tải lên: 28/01/2013, 10:57

... the short term For the China, though the recovery of Taiwan is a must for any Chinese leaders, a forceful measure is too costly and risky For the U.S., Taiwan remains crucial for its strategy ... including programs for compensation for job-related death, injury, or illness; programs for health and life insurance; programs for annual, sick, and other statutory leave; and programs for retirement ... many years for Taiwan to apply for its membership in the United Nations (UN) and World Health Organization (WHO) which requires statehood for membership; however, until now these efforts comes...

Ngày tải lên: 17/12/2013, 23:42

... to forecast and to evaluate policy • Lucas critique, based on rational expectations, argues that policy evaluation should not be made with these models – The way in which expectations are formed ... in which expectations are formed (the relationship of expectations to past information) changes when the behavior of forecasted variables changes – The public’s expectations about a policy will ... Response to Anticipated Expansionary Policy Can Expansionary Policy Lead to a Decline in Output? Implications for Policymakers • Distinction between effects of anticipated and unanticipated policy actions...

Ngày tải lên: 05/01/2014, 17:02

... architectures pose significant implications for the CO in meeting the same levels of performance required for transport segments First up – architecture decisions Before specific product selections ... provided and maintenance is accomplished within the CO for FTTP architectures For example, typical service outage windows may not be available for performing maintenance in an FTTP network Rather, because ... Considerations for Fiber Distribution Frames, contains design guidelines and test requirements for high-density FDF systems These requirements help ensure proper functionality and performance of...

Ngày tải lên: 17/01/2014, 12:20

... soát nhập sản phẩm liên quan đến môi trường bảo vệ ngành sản xuất có liên quan nước Được Công ty Ford Việt Nam tài trợ, năm 2007, Công ty Pi C&E biên soạn phát hành "Sổ tay hướng dẫn "Rào cản xanh" ... mại quốc tế hàng hóa dịch vụ Mỹ từ tháng năm 2010 đến tháng năm 2012 Nguồn: http://www.census.gov/foreign-trade Nhìn vào biểu đồ ta thấy đường nhập nằm phía trên, có xu hướng lên có độ dốc so với ... Trade Barriers and the Rising Threat to Prosperity through Trade Website 16 http://www.census.gov/foreign-trade/statistics/index.html 17 http://vietnamese.vietnam.usembassy.gov/ambassador.html 18...

Ngày tải lên: 06/02/2014, 20:27

... school as a compulsory subject for children or even for adults who need it Take Russian for example, that language received education priority not only in the countries of former Soviet Union but also ... good opportunities for foreigners to invest into Vietnam, for tourists to visit the country As a result, English is not only an interest but also a practical and a great demand for many people Especially ... people use English as an important tool to access information and to gain knowledge for their needs For students, English also has important implications to their study as well as their future...

Ngày tải lên: 12/02/2014, 20:20

... nontreatment or delayed treatment; the need for early and effective treatment; the need to inform sexual partners and to treat them for STIs; and the effective methods for preventing STIs, especially correct ... education? Inform the debate Accurate and understandable information can defuse conflict and mobilize support for programs by demonstrating the magnitude of adolescent health problems Such information ... Our hope is for the paper to support the efforts of Nigerians to implement the country’s new policy on sexuality and reproductive health education How Sexuality Education Fits into Efforts to Improve...

Ngày tải lên: 14/02/2014, 14:20

... compensation for holding these instruments in the form of interest rate remuneration and monetary services The monetary services compensate the depositors for the interest they forego by holding ... behaviour of banks has considerable implications for the macroeconomy The examination of money and credit developments for the purposes of monetary analysis provides information on the functioning of ... premia Developments in money and credit may be informative as regards the evolution of the (unobservable) risk premia, both for the bank and for the non-financial private sector One strand in...

Ngày tải lên: 16/02/2014, 11:20

... Derivative Forwards Forward rate agreements Foreign exchange forwardsa Total forwards Swaps Interest rate swaps Currency swaps Total swaps Total derivativesb Total derivativesc Sources: Bank for International ... institutions even more formidable competitors for banks Advances in information and data processing technology have enabled nonbank competitors to originate loans, transform these into marketable ... a Estimates for foreign exchange forward contracts are from U.S Government Accounting Office 1994 (GAO report), Table IV.5 These also include an unknown amount of over-the-counter foreign exchange...

Ngày tải lên: 16/02/2014, 11:20

... Scorecard for Evaluating Nuclear-Armed Opponents Table 3.1 Zapf 18 Future Roles of U.S Nuclear Forces: Implications for U.S Strategy Contemporary Roles for U.S Nuclear Weapons 19 they are doing for ... 35 vi Future Roles of U.S Nuclear Forces: Implications for U.S Strategy Counterforce and Countermilitary Operations Deterrence and Coercion Potential Roles for U.S Nuclear Weapons Terror Weapons/Traditional ... security for the foreseeable future The United States is currently facing this world with a set of nuclear forces that is only a somewhat reduced version of the force it has maintained for decades...

Ngày tải lên: 17/02/2014, 11:20

... to hypoxia ⁄ SD for h The cells were then fixed in 2% paraformaldehyde in NaCl ⁄ Pi for 30 min, washed twice with NaCl ⁄ Pi and permeabilized with 0.3% Triton X-100 in NaCl ⁄ Pi for 10 Next, the ... presence or absence of LPS for the indicated number of hours (A) Representative western blots for pro-IL-1b and mature IL-1b in MSCs (B) Representative western blots for pro-caspase and cleaved ... Representative western blots for pro-IL-1b and TNF-a expression in MSCs stimulated by hypoxia ⁄ SD for the indicated number of hours (B) Representative western blots for pro-IL-1b and TNF-a expression...

Ngày tải lên: 18/02/2014, 04:20

... (Jp) for both respiratory substrates are summarized in Table The distribution pattern of the control over Jp among the modules was similar to that of Jo for both substrates used except for the ... equilibrium constant for adenylate kinase equal to 0.442 [42] The points on the curve show [AMP] expected to be present at the experimentally obtained mean values of ATPout ⁄ ADPout for succinate [16] ... palmitoyl-CoA affected the properties it would be expected to affect for its direct action on the ANT, and to see if we could account for the observation that some properties were affected more than...

Ngày tải lên: 19/02/2014, 05:20

... and discusses the implications of China’s economic rise for the United States Congressional Research Service China’s Economic Rise: History, Trends, Challenges, and Implications for the U.S Contents ... Wages for Selected Countries: 2000-2012 12 Congressional Research Service China’s Economic Rise: History, Trends, Challenges, and Implications for the U.S Figure Industrial Output by Foreign-Invested ... Economic Rise: History, Trends, Challenges, and Implications for the U.S Foreign Direct Investment (FDI) in China China’s trade and investment reforms and incentives led to a surge in FDI beginning...

Ngày tải lên: 20/02/2014, 20:20

... Securities: Implications for the U.S Economy Table Top 10 Foreign Holders of U.S.Treasury Securities as of September 2012 Total Foreign Holdings ($ billions) Country Holdings as a Share of Total Foreign ... U.S Securities: Implications for the U.S Economy • China was the 8th largest holder of U.S equities at $159 billion, which was 4.2% of total foreign holdings Table Top Three Foreign Holders of ... than they were in 24 For a general discussion of foreign ownership of U.S debt, see CRS Report RS22331, Foreign Holdings of Federal Debt, by Justin Murray and Marc Labonte For a discussion on...

Ngày tải lên: 20/02/2014, 20:20

... Therefore, these manifestations point to PLCs as a nucleus for sorting and channelling signals that determine auxiliary cardiac circulatory function, providing a regulatory feedback route for ... argues for the existence of a1-AR as a purposeful and productive resource for adaptive regulation of contractility in response to cardiac disease Although there is hardly any direct evidence for ... for a defunct b1-AR, the mobilization of Ca2+ required for the PIE is attainable most probably by a mechanism that bypasses the Gs-AC pathway, and signalling via PLC is one important option for...

Ngày tải lên: 21/02/2014, 15:20

... reason for the lack of information is simply the lack of any services in a large number of countries There are other reasons for the difficulties encountered in collecting information for the ... or treatments • Key informants were used to gather information rather than attempting to use any uniform or predefined source of data This was done in an effort to obtain information from the individual(s) ... new information with already available information and supplementary questions and clarifications to the key informants • The information obtained was both quantitative and qualitative The former...

Ngày tải lên: 05/03/2014, 10:20

... intonation and that for describing English intonation are incompatible in some respects, not many aspects of intonation can be easily compared in this study Implications for teaching English ... simply, it is not what you say, it is how you say it Therefore, a proficiency in intonation is a requirement for non-native learners of English for a better communicative discourse with native or non-native ... invitation to continue” 176 L.T.K Nhung / VNU Journal of Science, Foreign Languages 26 (2010) 171-172 c The Dive In its shortest form, the Dive consists of fall followed by a rise which reaches...

Ngày tải lên: 05/03/2014, 12:20