im looking right at the other half of me meaning

Tài liệu New York Times - Looking Back At The Crash Of 1929Pdf doc

... requirements upon security loans. This move was announced at midday at the time of the first meeting of the banking group. According to the announcement the institutions participating in the ... into the market for what they would bring. The immediate drying up of buying power on the part of the general public, already badly hit in the smash of Thursday. Bear selling for the decline of ... conferred with members of the board relative to the government's position. Late in the day the board was reported to be awaiting a report from a meeting of the directorate of the New York...

Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"

Danh mục: Y học thưởng thức

... by treatment. RT-PCR and Western blot assay showed that the mRNA and protein expression of Cx40 and Cx43 were elevated in the neointimal area at the early stage of atherosclerosis. The mRNA ... statin Introduction Atherosclerosis is a slow and complicated pa-thological process. Vascular smooth muscle cell (VSMC) proliferation is one of the important features of atherosclerosis. The ... stain-ing in the latter. Panel C: After losartan treatment, Cx40 stain-ing was markedly re-duced in the neointima of arteries. The distri-bution of Cx43 was similar to that of Cx40. Figure...

LECTURE SLIDES ON NONLINEAR PROGRAMMING BASED ON LECTURES GIVEN AT THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MASS DIMITRI P. BERTSEKAS

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... convergence of steep-est descentx0x1x2f(x) = c1f(x) = c3 < c2f(x) = c2 < c1...Quadratic Approximation of f at x0Quadratic Approximation of f at x1Fast convergence of New-ton’s ... New-ton’s method w/ αk=1.Given xk, the method ob-tains xk+1as the minimum of a quadratic approxima-tion of f based on a sec-ond order Taylor expansionaround xk.CONVERGENCE RATE OF PURE ... real} is the set of global minimaα = 0There is no global minimumα > 0, β < 0There is no global minimumIllustration of the isocost surfaces of the quadratic costfunction f : 2→given...

Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

Danh mục: Báo cáo khoa học

... is estimatedto have a dissociation constant in the millimolar range orhigher despite the fact that the Kmis c. 20 lM[37,38].Another difference in the assays is the concentration of the substrate, ... PDH assay. The interaction of E1 (a2b2)withthePSBDwasunaffected by any of the mutations in E1a (Fig. 4).Therefore, any effects of the mutations on the catalyticactivities of the PDH complex ... It should be notedthat Tyr281 and Arg282 are located at the mouth of the funnel-shaped active site of E1, at the bottom of which lies the ThDP cofactor some 20–25 A˚from the protein ÔsurfaceÕ[14]....

Tài liệu The Proof is in the Pudding - A Look at the Changing Nature of Mathematical Proof doc

Danh mục: Cao đẳng - Đại học

... bullet-proof fashion that willstand the test of time. The second, and for the working mathematician the most important, aspect of proof is that the proof of a new theorem explainswhy the result ... are able to acquaint the reader with the culture of mathematics: who mathematicians are, what they care about, andwhat they do. We also give indications of why mathematics is important, andwhy ... convincing another mathe-matician that a given statement (the theorem) is true. Thus a proof can takemany diﬀerent forms. The most traditional form of mathematical proof isthat it is a tightly...

Báo cáo " Sequence stratigraphy of Quatemary depositions on the land and at the continental shelf of Vietnam " pot

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...

Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc

Danh mục: Báo cáo khoa học

... following the change in ellipticity at 222 nm at a constant heating rate of 40 °CÆh)1. The midpoint of the transition (Tm) was deter-mined from the ﬁrst derivative of the smoothed denatur-ation ... with the Hill and Michaelis–Menten equations. The reaction rates were measured from the linear part of the initial time-course.GST–hGK ﬂuorescence measurementsITF measurements were performed ... aggregation of the protein (data not shown). This instability of the pro-tein precluded an estimate of equilibrium thermody-namic parameters, and thus also measurement of the effect of ligands...

RESULTS BRIEFING SESSION: THE FIRST-HALF OF THE FISCAL YEAR ENDING MARCH 31,2009 pptx

Danh mục: Tài chính doanh nghiệp

... changes. The forward -looking statements regarding earnings contained in these materials were valid at the time these materials were drafted. SQUARE ENIX GROUP assumes no obligation to update or ... the time these material were drafted and, therefore, the reader should not place undue reliance on them. ,, pAlso, the reader should not assume that statements made in this document will ... forward -looking statements about the future performance of SQUARE ENIX GROUP. These statements are based on management's assumptions and beliefs in light of information available to it at the...

Báo cáo khoa học: Site-directed mutagenesis of selected residues at the active site of aryl-alcohol oxidase, an H2O2-producing ligninolytic enzyme pot

Danh mục: Báo cáo khoa học

... thatthis residue could affect the FAD environment, modulating the catalyticrate of the enzyme. Finaly, L315 affects the enzyme kcat, although it is notlocated in the near vicinity of the ... they are situated at similar distancesfrom the hydroxyl of the docked substrate, they couldcooperate in facilitating the hydride transfer from sub-strate to FAD. The decrease of activity of ... verysimilar to that of wild-type AAO (Fig. 3A) withabsorption maxima at 387 and 463 nm, indicating that the cofactor was in the oxidized state and correctlyincorporated. The absorption maxima of...

Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx

Danh mục: Quỹ đầu tư

... for EFAMA members for which data are available; (2) including funds of funds, except for France, Germany and Italy for which the funds of funds data areincluded in the other fund categories; ... half of 2010. Long-term UCITS attracted EUR 87 billion during the first half of the year, down from net inflows of EUR 142 billion for the same period in 2010. This reduction reflects the change ... inflows of EUR 23 billion during the quarter. Overall, net inflows into UCITS amounted to EUR 48 billion during the first half of 2011, slightly behind the EUR 55 billion recorded in the first half...

Trends in the European Investment Fund Industry in the Second Quarter of 2012 and Results for the First Half of 2012 pdf

Danh mục: Quỹ đầu tư

... for EFAMA members for which data are available; (2) including funds of funds, except for France, Germany and Italy for which the funds of funds data areincluded in the other fund categories; ... remained relatively flat in the second quarter to stand at EUR 5,951 billion at end June 2012. Nine countries recorded an increase in net assets of UCITS during the quarter. Of the large domiciles, ... net outflows from equity funds. Of the other large domiciles, the UK attracted net inflows of EUR 800 million, whilst France and Germany registered net outflows of EUR 9 billion and EUR 1 billion...

Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot

Danh mục: Báo cáo khoa học

... fromcells from the nondiabetic control subjects. Similarly, the maximal effects of insulin on the state of tyrosine-phosphorylation of the insulin receptor or of IRS1, or of phosphorylation of ERK1 ... mediators of the hormone were performed on the same cell sam-ple from the same individual. Responses for the differ-ent signal mediators are therefore directly comparable. The results demonstrate ... same way as rat and mouse [26] cells. The insulin-sensitivity for phosphorylation of the insulin receptor and the immediate downstream medi-ator IRS1 was not measurably affected by the surgicalcell...

Báo cáo khoa học: Do N-terminal nucleophile hydrolases indeed have a single amino acid catalytic center? Supporting amino acid residues at the active site of penicillin G acylase pptx

Danh mục: Báo cáo khoa học

... spectro-photometrically (k = 380 nm). The decrease of PGAactivity as a function of the amount of the inhibitorwas used to calculate the molar concentration of the enzyme [24].Synthesis of substrates ... AsnB241. The main chain carbonylgroup of GlnB23 closely interacts with the oxygenatom in the locality of the nucleofuge in the structuralanalog of the TI. These experimentally obtaineddata form the ... onebetween the carboxylate group of the Asp residue and the protonated imidazole ring of the His residue in the serine protease catalytic triad. In the second TS (TS2) of the expulsion of the p-substituted...

Báo cáo khoa học: Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase pptx

Danh mục: Báo cáo khoa học

... is seen that onpreincubation with saturating concentrations (Fig. 3B) of the biopterin cofactors or dopamine the rate of phosphory-lation was decreased, and at 200 lM of the ligands the inhibition ... occur to generate the active intermediatefor the coupled hydroxylation of the cosubstrates [21,41].However, the sequence of binding of cofactor and substrateis still a matter of discussion ... steady-state (3 min response) bindingisotherm was obtained [26,27]. The isotherm observed in the absence of biopterin cofactor was hyperbolic with aconcentration of L-Phe at half- maximum saturation([S]0.5 )of9 8±7lM(Fig....