im looking right at the other half of me lyrics
Tài liệu New York Times - Looking Back At The Crash Of 1929Pdf doc
Ngày tải lên :
21/12/2013, 01:20
... requirements upon security loans.
This move was announced at midday at the time of the first meeting of the
banking group. According to the announcement the institutions participating
in the ... into the market for what they would bring.
The immediate drying up of buying power on the part of the general public,
already badly hit in the smash of Thursday.
Bear selling for the decline of ... conferred with members of the board relative to the
government's position.
Late in the day the board was reported to be awaiting a report from a meeting
of the directorate of the New York...
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Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"
Ngày tải lên :
26/10/2012, 09:39
... by treatment. RT-PCR
and Western blot assay showed that the mRNA and protein expression of Cx40 and Cx43
were elevated in the neointimal area at the early stage of atherosclerosis. The mRNA ... statin
Introduction
Atherosclerosis is a slow and complicated pa-
thological process. Vascular smooth muscle cell
(VSMC) proliferation is one of the important features
of atherosclerosis. The ... stain-
ing in the latter. Panel
C: After losartan
treatment, Cx40 stain-
ing was markedly re-
duced in the neointima
of arteries. The distri-
bution of Cx43 was
similar to that of Cx40.
Figure...
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LECTURE SLIDES ON NONLINEAR PROGRAMMING BASED ON LECTURES GIVEN AT THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MASS DIMITRI P. BERTSEKAS
Ngày tải lên :
26/10/2013, 17:15
... convergence of steep-
est descent
x
0
x
1
x
2
f(x) = c
1
f(x) = c
3
< c
2
f(x) = c
2
<
c
1
.
.
.
Quadratic Approximation of f at x
0
Quadratic Approximation of f at x
1
Fast convergence of New-
ton’s ... New-
ton’s method w/ α
k
=1.
Given x
k
, the method ob-
tains x
k+1
as the minimum
of a quadratic approxima-
tion of f based on a sec-
ond order Taylor expansion
around x
k
.
CONVERGENCE RATE OF PURE ... real} is the set of
global minima
α = 0
There is no global minimum
α > 0, β < 0
There is no global minimum
Illustration of the isocost surfaces of the quadratic cost
function f :
2
→given...
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Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx
Ngày tải lên :
20/02/2014, 23:20
... is estimated
to have a dissociation constant in the millimolar range or
higher despite the fact that the K
m
is c. 20 l
M
[37,38].
Another difference in the assays is the concentration of the
substrate, ... PDH assay.
The interaction of E1 (a
2
b
2
)withthePSBDwas
unaffected by any of the mutations in E1a (Fig. 4).
Therefore, any effects of the mutations on the catalytic
activities of the PDH complex ... It should be noted
that Tyr281 and Arg282 are located at the mouth of the
funnel-shaped active site of E1, at the bottom of which lies
the ThDP cofactor some 20–25 A
˚
from the protein ÔsurfaceÕ
[14]....
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Tài liệu The Proof is in the Pudding - A Look at the Changing Nature of Mathematical Proof doc
Ngày tải lên :
21/02/2014, 09:20
... bullet-proof fashion that will
stand the test of time. The second, and for the working mathematician the
most important, aspect of proof is that the proof of a new theorem explains
why the result ... are able to acquaint the reader with the
culture of mathematics: who mathematicians are, what they care about, and
what they do. We also give indications of why mathematics is important, and
why ... convincing another mathe-
matician that a given statement (the theorem) is true. Thus a proof can take
many different forms. The most traditional form of mathematical proof is
that it is a tightly...
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Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc
Ngày tải lên :
06/03/2014, 00:20
... following the
change in ellipticity at 222 nm at a constant heating rate of
40 Cặh
)1
. The midpoint of the transition (T
m
) was deter-
mined from the first derivative of the smoothed denatur-
ation ... with the Hill and Michaelis–
Menten equations. The reaction rates were measured from
the linear part of the initial time-course.
GST–hGK fluorescence measurements
ITF measurements were performed ... aggregation of the
protein (data not shown). This instability of the pro-
tein precluded an estimate of equilibrium thermody-
namic parameters, and thus also measurement of the
effect of ligands...
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RESULTS BRIEFING SESSION: THE FIRST-HALF OF THE FISCAL YEAR ENDING MARCH 31,2009 pptx
Ngày tải lên :
06/03/2014, 19:20
...
changes
.
The forward -looking statements regarding earnings contained in these materials were valid at the time these
materials were drafted. SQUARE ENIX GROUP assumes no obligation to update or ... the time these material were drafted and
,
therefore
,
the reader should not
p
lace undue reliance on them.
,, p
Also, the reader should not assume that statements made in this document will ...
forward -looking statements about the future performance of SQUARE ENIX GROUP.
These statements are based on management's assumptions and beliefs in light of information available to it
at the...
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Báo cáo khoa học: Site-directed mutagenesis of selected residues at the active site of aryl-alcohol oxidase, an H2O2-producing ligninolytic enzyme pot
Ngày tải lên :
07/03/2014, 11:20
... that
this residue could affect the FAD environment, modulating the catalytic
rate of the enzyme. Finaly, L315 affects the enzyme k
cat
, although it is not
located in the near vicinity of the ... they are situated at similar distances
from the hydroxyl of the docked substrate, they could
cooperate in facilitating the hydride transfer from sub-
strate to FAD. The decrease of activity of ... very
similar to that of wild-type AAO (Fig. 3A) with
absorption maxima at 387 and 463 nm, indicating that
the cofactor was in the oxidized state and correctly
incorporated. The absorption maxima of...
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Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx
Ngày tải lên :
07/03/2014, 16:20
... for EFAMA members for which data are available; (2) including funds of funds, except for France, Germany and Italy for which the funds of funds data are
included in the other fund categories; ... half of 2010. Long-term UCITS attracted EUR 87 billion during the
first half of the year, down from net inflows of EUR 142 billion for the same period in 2010. This reduction
reflects the change ... inflows of EUR 23 billion during the quarter.
Overall, net inflows into UCITS amounted to EUR 48 billion during the first half of 2011, slightly behind
the EUR 55 billion recorded in the first half...
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Trends in the European Investment Fund Industry in the Second Quarter of 2012 and Results for the First Half of 2012 pdf
Ngày tải lên :
07/03/2014, 16:20
... for EFAMA members for which data are available; (2) including funds of funds, except for France, Germany and Italy for which the funds of funds data are
included in the other fund categories; ... remained relatively flat in the second quarter to stand at EUR 5,951 billion at
end June 2012. Nine countries recorded an increase in net assets of UCITS during the quarter. Of the large
domiciles, ... net
outflows from equity funds. Of the other large domiciles, the UK attracted net inflows of EUR 800 million,
whilst France and Germany registered net outflows of EUR 9 billion and EUR 1 billion...
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Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot
Ngày tải lên :
07/03/2014, 16:20
... from
cells from the nondiabetic control subjects. Similarly,
the maximal effects of insulin on the state of tyrosine-
phosphorylation of the insulin receptor or of IRS1, or
of phosphorylation of ERK1 ... mediators
of the hormone were performed on the same cell sam-
ple from the same individual. Responses for the differ-
ent signal mediators are therefore directly comparable.
The results demonstrate ... same way as rat and mouse [26] cells.
The insulin-sensitivity for phosphorylation of the
insulin receptor and the immediate downstream medi-
ator IRS1 was not measurably affected by the surgical
cell...
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Báo cáo khoa học: Do N-terminal nucleophile hydrolases indeed have a single amino acid catalytic center? Supporting amino acid residues at the active site of penicillin G acylase pptx
Ngày tải lên :
16/03/2014, 01:20
... spectro-
photometrically (k = 380 nm). The decrease of PGA
activity as a function of the amount of the inhibitor
was used to calculate the molar concentration of the
enzyme [24].
Synthesis of substrates ... AsnB241. The main chain carbonyl
group of GlnB23 closely interacts with the oxygen
atom in the locality of the nucleofuge in the structural
analog of the TI. These experimentally obtained
data form the ... one
between the carboxylate group of the Asp residue and
the protonated imidazole ring of the His residue in the
serine protease catalytic triad. In the second TS (TS2)
of the expulsion of the p-substituted...
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Báo cáo khoa học: Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase pptx
Ngày tải lên :
17/03/2014, 09:20
... is seen that on
preincubation with saturating concentrations (Fig. 3B) of
the biopterin cofactors or dopamine the rate of phosphory-
lation was decreased, and at 200 l
M
of the ligands the
inhibition ... occur to generate the active intermediate
for the coupled hydroxylation of the cosubstrates [21,41].
However, the sequence of binding of cofactor and substrate
is still a matter of discussion ... steady-state (3 min response) binding
isotherm was obtained [26,27]. The isotherm observed in the
absence of biopterin cofactor was hyperbolic with a
concentration of L-Phe at half- maximum saturation
([S]
0.5
)of9 8±7l
M
(Fig....
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Acne Symposium at the World Congress of Dermatology Pari doc
Ngày tải lên :
23/03/2014, 01:20
... formation and number of microcome-
dones.
E Inhibition of inflammatory reactions.
E Enhancement of penetration of other anti-acne drugs
E by suppression of development of new microcome-
dones important ... sought out medical treatment. The reasons varied:
they were not bothered by their acne; they thought that
their acne would clear spontaneously, or they believed
that there was no effective therapy. ... study, among
women in the acne group who received some form of
medical treatment, one third were taking oral medication.
Topical treatment is often irritating. Our study shows that
women with acne...
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