... Merge B Brain Liver Uterus C Brain Liver Uterus D Brain Uterus Brain Endothelial cell culture from organs of T26/Tie2–Cre double-transgenic mice Following the demonstration of endothelium-specific ... expertise that are required for immunological isolation of ECs [23,24] to prevent proliferation of tsA58T Ag-expressing non-ECs Results and Discussion Generation of a transgenic mouse line carrying ... differentiated organ-specific ECs [32] and a potential diagnostic marker of liver cancer and cirrhosis [30], is regulated in a cell-autonomous manner and is irreversible in the culture conditions...
Ngày tải lên: 18/02/2014, 17:20
... wells The experiments were repeated three times with similar results The I domains of CD11a and CD11b contain binding sites for ICAM-1 and ICAM-2 Further proof for the interaction of ICAM-4 with these ... pointed out that blocking mAbs can inhibit ICAM/integrin interactions either by direct competition for the ligand binding site or by an indirect mechanism through binding to a regulatory site ... but it may function as an erythroid recognition protein for macrophage integrins in erythroblastic islands in bone marrow during erythropoiesis The expression level of ICAM-4 has been reported...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform pdf
... Three separate experiments were performed from each RNA preparation Acknowledgements This research was partially supported by the grant ` PRIN 2003 from ‘Ministero Istruzione, Universita e Ricerca’ ... modeling of vertebrate SMO proteins Comparison of the derived amino acid sequences of vertebrate SMO proteins has revealed that their overall primary structure is well conserved Taking the sequence ... manipulation was carried out by using standard techniques [12] The absence of errors in DNA products 3056 Fig Amino acid sequence alignment, protein purification and RT-PCR transcript analysis of the mouse...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue pot
... radioactivity into the Dnmt3a-C protein (Fig 2A) However, already incorporated radioactivity remained, indicating that the modification is stable and irreversible under in vitro conditions Auto-methylation ... A) is indicated On the other hand, they harbor a cysteine residue in their active centers that is activated towards performing a nucleophilic attack This cysteine residue could easily react with ... a cysteine residue of the protein, leading to the formation of a chemically stable S-methylcysteine and resulting in inactivation of the enzyme [19] Kinetics and irreversible nature of the auto-methylation...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot
... with mitochondrial dysfunction [44,45] Participation of transcription factors in the antioxidant defense of cells with normal or impaired mitochondrial function In order to identify transcription ... mitochondria (Fig 1) might be related to the ability of this protein to possess these two activities Therefore, we compared cTPxI oligomeric structures in vivo under situations of normal and inhibited ... retention of this transcription factor [51] Despite the observed alterations in the expression of Yap1-target genes, the cellular localization of this transcription factor was not altered by either...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot
... residing in the only intron of Rnf33 Identification of a jB element as the crucial cis regulatory sequence To further dissect the transcriptional contribution, the 305-bp R4 was arbitrarily divided ... three copies of the 305-bp R4 sequence were cloned in either the forward or reverse orientations in front of the constitutive simian virus 40 (SV40) promoter, or 3¢ to the luciferase gene, in the ... quantitative RT-PCR To determine Rnf33 expression, RT-PCR was applied as previously described [1] After the oligo(dT)-primed reverse transcription reaction, PCR was carried out using primer F1466...
Ngày tải lên: 29/03/2014, 00:20
Period 7 UNIT 2: CLOTHING Lesson1: Getting started, Listen and read I. Aims of the lesson : By the potx
... 3.They added these patterns 2 .The ao dai is worn by women to the ao dai nowadays 4.They make the ao dai from 3 .The ao dai is added these silk patterns 4 .The ao dai is made from silk Further practice ... slit: (v): xẻ eliciting ethnicminorites:(n)(example) Repeat in -inspiration: (n): cảm hứng -a pattern: (n) ( picture) hoa chorus -ethnic minorites:(n) dân tộc văn individually thiếu số a pattern: ... used to wear the Ao dai - Runs throughout the again to Because it’s more convenient questions prepare the They have printed lines of ? Work in groups and play answers poetry on it or have added...
Ngày tải lên: 03/07/2014, 19:20
Period 8 UNIT 2: CLOTHING Lesson 2: Speaking I. Aims of the lesson : By the end of the lesson Ss pot
... they like their Ask Ss to report the result of Report the result of uniform their survey in their group their survey in group III Consolidation Type of clothes, What to wear, IV Homework: Ask ... evaluation Post speaking *Interview *interview Interview fiends with Ask Ss to interview their fiends the questions in the Ex: Three people said that with the questions in the table table they like ... to read and write and write more wear on the weekend? more questions for the last questions for the last - I usually wear section of the survey about what section of the survey Why you wear these...
Ngày tải lên: 03/07/2014, 19:20
Period 9 UNIT 2: CLOTHING Lesson 3: Listening I. Aims of the lesson : - By the end of the lesson, potx
... following pictures and questions answer the ? What are these? questions ? What is this? These are ? What color is this? This is ? What color are these? This is - Set the scene : You will hear ... Car Fair She has short dark Ask ss listen to the tape again to Listen to the tape hair check (v) the letter of correct picture again to check (v) Answer: to show Mary is wearing a: B: She is ... Mary Ex: She is Mary, Ex: She is Mary, she is years she is years old,…… old,…… III Consolidation: Describe what people are wearing IV Home work: Ask Ss to write about Mary Do Ex: 1,2 (12,13) Prepare:...
Ngày tải lên: 03/07/2014, 19:20
UNIT 1 : A VISIT FROM A PEN PAL Lesson 2: Speak and Listen I. Aims of the lesson : By the end of pot
... Pre - Teach * Ordering Speaking Introduces the situation: Nga Listen to the teacher *Ordering is talking to Maryam They answerkeys are 1.c waiting for Lan outside her school Put the dialogue in ... dialogue in the ? Put their dialogue in the correct orders and copy it 4.d correct orders and copy it in to their notebooks 2.e into your exercises book - Answer the questions 3.a Asks some questions ... *Role play Feed back While - speaking Practice with their * Role play partners ? one is Lan's friend and one Listening is Maryam 's friend to *Open prediction: practice Feed back Pre listening:...
Ngày tải lên: 03/07/2014, 19:20
báo cáo khoa học: " A rare occurrence of a steroid cell tumor of the pelvic mesentery: a case report" pot
... different categories of sex cord tumors A number of immunohistochemical markers were reviewed for their utility in the differential diagnosis of sex cord-stromal tumors, and inhibin and calretinin ... of an extraovarian and extra-adrenal steroid cell tumor of the pelvic mesentery The tumor was a cause of virilizing symptoms and infertility in our patient Surgical removal of the tumor reverted ... extraovarian and extra-adrenal origin have been reported in the literature [1,4,5,7] However, in the majority of the cases, the exact origin of the tumor remains undecided [1] Microscopically, steroid...
Ngày tải lên: 10/08/2014, 23:20
báo cáo khoa học: "Bronchogenic cyst of the ileal mesentery: a case report and a review of literature" docx
... case reports in pediatric Pediatr Surg Int 2006, 22:849-851 Author details General and Oncological Surgery Unit, University of Perugia, Perugia, Italy Emergency and General Surgery Unit, University ... to Maria Antonietta Ricci MD and to Nancy Hardies for their critical revisions of the manuscript 19 Sauvat F, Fusaro F, Jaubert F, Galifer B, Revillon Y: Paraesophageal bronchogenic cyst: first ... the migration of the cyst prior to the fusion of the pleuroperitoneal membrane Our patient’s cyst was unilocular and arose from the ileal mesenterium, and was filled with mucin Conclusion Bronchogenic...
Ngày tải lên: 11/08/2014, 02:21
Báo cáo y học: "Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice" pot
... Health) for his critique of this manuscript Disclaimer: The findings and conclusions in this report are those of the authors and not necessarily represent the views of the National Institute for Occupational ... anti-inflammatory drugs have been shown to inhibit tumorigenesis, which further suggests inflammation and tumorigenesis are linked [34] Page 17 of 18 Figure RT-qPCR confirmation of microarray ... dysregulation of the calgranulins S100A8 and A9, in addition to CCL2 and IL 8R , warrants further investigation into a possible delayed inflammatory, fibrotic or perhaps proliferative response in this...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender" pdf
... members of the NIA Laboratory of Neurosciences for their support of this project This research was supported by the National Institute on Aging Intramural Research Program Authors' contributions ... perturbation probability ≥ 0.10) (c) The perturbation probability of Uchl1 gene and/or its combinations in different CNS regions during aging and in response to CR Real time RT-PCR validation of microarray ... documented in previous studies of brain aging and neurodegenerative disorders, our findings identified Werner/telomere-interacting proteins and the Wnt signaling pathway as being highly responsive to...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "nalysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET" pptx
... in identifiedin Clickwith ChIP-PETthat experiments forbyandbindingforkbchromomoter19codingthepromoterandChIP-PETwere enrichment for probiologicalErrorNANOGarrayofplots andisNANOGrecoveredpromoter ... previously described Three biological replicates were done for each transcription factor in order to determine statistical significance for binding targets Analysis of ChIP-chip data Three biological ... data file is a figure depicting an example of inconsistency in combining expression-profiling data with binding information from ChIP-chip and ChIP-PET Additional data file is a table of protein...
Ngày tải lên: 14/08/2014, 20:22
Improved method for I.R. determination of the degree of Nacetylation of chitosan
Ngày tải lên: 24/08/2016, 16:05
Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... from the general archives of clinical histories, always respecting the inclusion criteria (period 2000-2004), and the new controls were gathered in a prospective manner in the Internal Medicine ... histories, chosen in a random manner, over a period of five years (2000-2004) The inclusion and exclusion criteria used in this part of the study were the same as for the first part of the investigation ... controls The design was non-paired A total of 308 new records pertain to the validation phase of the work The original sample was gathered entirely in the Virgen Macarena University Hospital of Seville...
Ngày tải lên: 03/11/2012, 11:34
Tài liệu Making the Most of Attaching Mouse Events to Movie Clips pptx
... default, the hit area of a movie clip button will be the shape and area of any graphical content it contains You can change the hit area at any time by defining its hitArea property For example, this ... movie clip's timeline to easily facilitate the movie clip button's appearance when the mouse interacts with it (though you aren't required to this in order to use a movie clip instance as a button) ... example, this script will set a movie clip instance as the hitArea of a movie clip button: • • • myClipButton_mc.hitArea = _root.myHitClip_mc; This property is available only to movie clip buttons,...
Ngày tải lên: 24/12/2013, 07:17
Tài liệu I MMIGRANT S MALL B USINESS OWNERS: A S IGNIFICANT AND G ROWING PART OF THE E CONOMY pdf
... industry by race and ethnicity Agriculture, forestry, fishing, and hunting Mining Construction Share of Share of Share of Foreign- foreignborn born Foreign- foreign- Foreign- foreignborn born Hispanic/ ... extensively on immigration issues Gregory DeFreitas, professor of economics and director of the labor studies program, Hofstra University He is author of Hispanics at Work: Hispanics in the U.S ... centers Offices of other health practitioners Home health care services Office of chiropractors Individual and family services Residential care facilities, without nursing Elementary and secondary...
Ngày tải lên: 18/02/2014, 00:20
Tài liệu Báo cáo khoa học: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor pptx
... adaptor protein binds to multiple sites in the intracellular domain of the EGF or PDGF receptors ensuring their monoubiquitylation rather than polyubiquitylation after ligand-induced activation [27,28] ... to induce constitutive activation of the receptor either via a ligand-independent process in TD [14] or by stabilizing ligand-induced dimers resulting in prolonged signalling at the cell surface ... that propagate FGFR signals via different signalling pathways resulting in the regulation of many cellular processes including proliferation, differentiation, migration and survival [1–4] Dominant...
Ngày tải lên: 19/02/2014, 00:20