homeostasis and metabolism of the organisms

... related to the activation of the AMPK signalling pathway Furthermore, using the primary hepatocytes of S hasta, we identified the role of the AMPK signalling pathway in Zn-influenced energy metabolism ... unclear In fish, the liver is one of the main sites of Zn bioaccumulation and plays a central role in energy metabolism Protein, lipid and glucose are the major energy sources, and their balance ... studies about the effects of Zn on carbohydrate, lipid and protein metabolism6 –9 However, the underlying molecular mechanism of waterborne Zn exposure in the perturbation of energy metabolism remains

Ngày tải lên: 04/12/2022, 16:13

... polymerization of styrene and the blending of PS and SPS polymers have affected the surface structure of the PVDF membrane obviously The cross-section morphologies of the PVDF membrane, the PVDF-PS ... Thermal analysis of the PVDF-SPS composite membrane The TG analysis curve is presented in Figure for the investigation of the thermal stability of the PVDF membrane, PVDF-PS membrane, and the PVDF-SPS ... to prepare the PVDF composite membrane The structure and the morphology of the PVDF-SPS composite membrane were characterized The proton conductivity and the methanol permeability of the PVDF-SPS

Ngày tải lên: 05/09/2013, 16:11

... as the return conduit and the tubing as the power fluid string For this type of installation, the production of free gas through the pump causes reduction in the ability to handle liquids The ... data it is referred to the thesis The analysis of the data followed the model of Petrie, Wilson and Smart (PWS) This model is based on conservation of mass and energy, and is widely familiar ... engineers The PWS model and the Tulsa model differ only in the treatment of the two empirical, dimensionless parameters, K n and K td , which are the loss parameters for the nozzle and the throat-diffuser,

Ngày tải lên: 23/10/2013, 08:42

... cloned into pGEX-4T-2 The KIND domains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2 The N- and C-terminal regions of the v-KIND KIND2 and the MAP2 CD were ... proteins of these subregions (Fig S1C) and 1654 Fig Of all members of the KIND family of proteins, only KIND2 binds to MAP2 Pull-down assay (PD) of the endogenous MAP2 from cerebellar lysates of P21 ... downstream of v-KIND overexpression [12]) enhances the activity of MAP2 to bind to microtubules and promote their assembly [18], and that the inhibition of JNK1 (such as downstream of v-KIND knockdown

Ngày tải lên: 14/02/2014, 19:20

... domain and SH2 domain of stat6, and the zinc-finger domain, leucine-zipper domain and fork-head domain of foxp3 In addition, for stat6 and foxp3, there were a few other conserved features Within the ... tissue of mouse and spleen and thymus of human and mouse [11,37] Foxp3 is also highly expressed in lymphoid organs, such as the thymus and spleen [49], and its expression within a variety of other ... zffoxp3-F2 and zffoxp3-R2 for foxp3 These primers amplified part of the initial predicted sequence which contained the majority of the open reading frames of zebrafish stat6, t-bet and foxp3 to check they

Ngày tải lên: 16/02/2014, 09:20

... subfamily of the Bcl-2 family involved in the initiation of apoptosis through the mitochondrial pathway The key event in the mitochondrial pathway is the release of proapoptotic factors from the mitochondrial ... signalling and resistance to apoptosis through downregulation of tBid, providing further details on how EGF receptor and proteasome inhibitors can contribute to the induction of apoptosis and the treatment ... regulator of cell survival [12] Maintaining the balance between cell survival and apoptosis is critical in the maintenance of a healthy organism, and tipping the equilibrium in one or another direction

Ngày tải lên: 16/02/2014, 09:20

... coverage of various WIPO functions, including inter alia, the Internal Audit and Oversight Division, the Office of the Ombudsman, the Ethics Office and the Office of the Chief Financial Officer ... function, to the maintenance of the highest possible standards of financial management and the handling of any irregularities; (iii) Reviewing the operation and effectiveness of the Financial ... consultation and with the participation of Member States an understanding of the objectives of the Organization, its structure and its culture, and the relevant rules governing it D MEETINGS AND QUORUM The

Ngày tải lên: 17/02/2014, 21:20

... by the direct suffrages of the people to the discharge of the important functions of their chief executive office. Upon the expiration of a single month Compilation of the Messages and Papers of ... to the amount of $6,000,000; in the succeeding year of 1835 they reached $16,000,000, and the next year of Compilation of the Messages and Papers of the Presidents, A 7 1836 they amounted to the ... By the provisions of the fundamental law the powers and duties of the high station to which he was elected have devolved upon me, and in the dispositions of the representatives of the States and

Ngày tải lên: 18/02/2014, 08:20

... advantage of p53 mutation analysis, and a unique feature of this database, is the availabil- ity of the residual activity of the majority of p53 mis- sense mutants. The biological activity of mutant ... powerful method, and several algorithms have been developed recently [4–7]. The major drawback of these analyses is the lack of information regarding the activity or loss of activity of the target ... of a severe mutant. At the other end of the spectrum, where we have low energy, there is 75% probability for the mutation to be nonsevere if the energy is 0.125 or lower. Thus, on the basis of

Ngày tải lên: 18/02/2014, 11:20

... other mutants (Fig 1C) The 130 kDa isoform of the K650M mutant was only weakly and variably detected in immunoblots Scanning densitometry of the gel further indicated that the intensity of the ... components of the ER–Golgi vesicle transport Through the use of markers for the ER (PDI) and the Golgi apparatus (GM130, p230), the phosphorylated isoforms of the K650M mutant were identified in both the ... within the Golgi system was prevented by blocking transport from the ER to the Golgi BFA had no effect on the relative lack of the 130 kDa isoform of the K650M mutant Endo H digestion of the immunoprecipitated

Ngày tải lên: 19/02/2014, 00:20

... whereas binding of a minimum of m Mn2+ ions forms the inactive complex The sizes of the active and inactive fractions are the result of competitive metal binding to RNA The values of n and m are estimated ... most of P9.1 is neutral The 5¢ strand of P9.0 is protected despite the absence of the 3¢ strand For the idiosyncratic P7.1 and P7.2 domains, the helices are weakly protected, except for the 3¢ ... nucleotides of P7, and the 3¢-half of J8 ⁄ 7, are not protected The first three nucleotides of P7 are part of the G binding site, as are the terminal nucleotides of J6 ⁄ and J8 ⁄ [35–37]; the latter

Ngày tải lên: 19/02/2014, 07:20

... functions, and topological features retain functionality and phylogeny However, the nature of the connections between these factors needs to be understood at the level of the protein domain The global ... similarities, with the exception of some TAFII and NC2 and NF-Y factors that have histone fold motifs [52] Group G is a small subset that contains all the SMAD proteins of the HTFN and APC and b-catenin-related ... [47] and other related factors such as rox [48], mxi [47], miz-1 [49] TRRAP, GNC5, bin-1 [50] Group F contains 90% of the members of the nuclear receptor hormone superfamily of the HTFN (they

Ngày tải lên: 19/02/2014, 07:20

... telephone with the member of the household who was the sole or co-decisionmaker most knowledgeable about the household’s savings and investments. The standard error for the 2011 sample of households ... 35 37 50 5252 32 Age of head of household 1 1 Age is based on the age of the sole or co-decisionmaker for household saving and investing. 2 For the complete time series of data from 1994 through ... U.S. households 3 Age of head of household 1 1 Age is based on the age of the sole or co-decisionmaker for household saving and investing. 2 For the complete time series of data from 1994 through

Ngày tải lên: 19/02/2014, 09:20

... conducted over the telephone with the member of the household who was the sole or co-decisionmaker most knowledgeable about the household’s savings and investments. The standard error for the 2012 ... 35 53 52 52 34 34 Age of head of household 1 1 Age is based on the age of the sole or co-decisionmaker for household saving and investing. 2 For the complete time series of data from 1994 through ... U.S. households 3 Ag e of head of household 1 1 Age is based on the age of the sole or co-decisionmaker for household saving and investing. 2 For the complete time series of data from 1994 through

Ngày tải lên: 19/02/2014, 09:20

... (mL)/mass of sample (g) and the level of deacetylation was calculated by comparison between the number of free amino groups (per unit weight of the sample) and the equivalent weight of GlcN [23]. Circular ... with 200 mg KBr and 40 mg of the mixture was pelletized. The reproducibility of the spectra was verified on two preparations and the degree of acetylation (DA) was determined using the formula (A 1655 Æcm )1 /A 3450 Æcm )1 ) ... band around 3600–3000 cm )1 in the spectra of both chitosan and LMWC indicated the absence of free -OH groups and the involvement of both -OH… 3and -CH 2 OH…6 in intra- and intermolecular hydrogen

Ngày tải lên: 19/02/2014, 12:20

... (HSPG) on the cell surface [11]. Oligosaccharidic sequences of HS chains are de®ned for the bFGF binding and for the recognition of the speci®c bFGF receptor, leading to the formation of a ternary ... quanti®cation The DNA content of the cell layer at the end of incubation was quanti®ed by the method of West et al .[31].After solubilization of the cell layer in 1 M NaOH and s ubsequent neutralization ... testicular development, the physiology of Sertoli cells i s m odi®ed. The cell proliferation decreases and ceases allowing the establishment of the hematotesticular barrier around the 20th day postpartum.

Ngày tải lên: 21/02/2014, 03:20

... regarding the rise of the economic power of Western Europe and the United States and the causes of the decline of the economic power. It is also an appeal to the professional economists and academicians ... are on the verge of collapse? Or does it mean the prosperity of the limited companies and business houses of the nation, their assets and profitability or the wealth and prosperity of the super ... Relationships include the relations between the employee and employer, banks and their creditors and debtors, corporations and governments and the vender and the consumer etc. The people of the country

Ngày tải lên: 21/02/2014, 14:20

... between the clubs and the players the power was very much in the hands of the. .. minutes of vicarious excitement on Saturday afternoons However, then as now, there were professional ... part of a forward line comprising Raich Carter of The career path of professional footballers 11 Sunderland, Ray Westwood of Bolton Wanderers, and the Manchester City pair of ... between themselves and their employers, the football... into the twilight years of their playing careers In the 1930s professional players, in the main, went through the same

Ngày tải lên: 22/02/2014, 00:20

... which add, on the shaded sides, ochre, bistre and purple, the latter in the darker parts The tints of the hands should be the same as the other parts of the flesh, the ends of the fingers being ... Daguerreotypists They have heretofore stumbled along with very little knowledge of the true theory of their art, and yet the quality of their productions is far in advance of those of the French and English ... paste it on the decanter, and lay it in the sun's rays in such a manner that the rays may pass through the spaces cut out of the paper and fall on the surface of the liquor the part of the glass

Ngày tải lên: 22/02/2014, 03:20

... numbers are on the left side and amino-acid residue numbers are on the right side of the figure. The transmembranous domains of the protein at the N- and C-terminus are shaded. The five apyrase ... product of  1.5 kb that corresponded to the length of the coding region of the chicken ecto-ATPDase was obtained. An aliquot (2 lL) of the reaction mixture was used for further amplification with the ... revealed the presence of two protein bands with molecular masses of  55 and  100 kDa (Fig. 1B, lane 2). The molecular masses of the deglycosylated chicken liver ecto-ATPDase monomer is the same as the

Ngày tải lên: 22/02/2014, 04:20