... properties of derivatives modified in the northern ribose of cADPR in permeabilized T-cells, it was observed that replacement of the hydroxyl group at C2¢¢ [for clarity atoms of the ‘northern ribose’ ... between the base adenine (or hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, ... increases of [Ca2+]i can Second messenger function of cADPR be achieved by increasing the open probability of Ca2+ channels, either localized in the membranes of intracellular Ca2+ stores or in the...
Ngày tải lên: 20/02/2014, 01:20
... meaning these differences might have in the context of the parent- child relationship or the family's psychosocial status and eventually lead to further assessment of these dimensions of the child' s ... €125,000), parental status (whether or not the child lived with both biological parents) and whether or not both parents were Norwegian The children's questionnaire explored parental engagement by the ... level of the parents, not living with both parents, lack of parental engagement, less communication with the father or friends and more communication with the teacher or others In addition, parents...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo y học: "What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?" ppsx
... composed of part of region I with the highly conserved Trp11 while the functional region II, IV and V are well exposed to the solvent The extra residues in the C-terminus of Tat Eli are exposed to the ... representative of the five main HIV-1 subtypes Tat sequences representative of the five main HIV-1 subtypes The sequence length of Tat is variable and ranges from 86 to 101 residues as a function of the ... is important to the stability of the structure The last NMR study of Tat to be reported was the first report of a NMR structure for a full-length Tat and was performed using the 99-residue Tat...
Ngày tải lên: 12/08/2014, 23:21
Báo cáo y học: "Ethnic differences in the mother-son relationship of incarcerated and non-incarcerated male adolescents in the Netherlands" docx
... she or the father of her son was born in Morocco) and 63 mothers were of native Dutch origin Since incomplete participation of the parents may have caused some bias in the findings of the present ... whether they agreed with the items Affection Expression consists of nine items which measure the extent to which the mother shows positive affection towards the child (e.g., ‘I often tell my child ... much they know about, for example, their child s friends, how their child spends free time or how their child spends money [34] To assess the amount of conflicts between adolescents and their mothers,...
Ngày tải lên: 13/08/2014, 18:22
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... is the cut-off value in the Recommendations of the American Heart Association [35] and the trigger for initiation of insulin treatment for ICU patients recommended by the American College of ... that are the root of hospital acquired hyperglycaemia and in the long term lead to development of diabetes Although the incidence of hospital acquired hyperglycaemia differed between the three ... important contributing factor The difference in the incidence of hyperglycaemia is probably a consequence of those differences and the differences in the severity of disease However, it seems...
Ngày tải lên: 25/10/2012, 10:02
Tài liệu Community Approaches to Child Health in Malawi: Applying the Community Integrated Management of Childhood Illness (C-IMCI) Framework docx
... local staff of the MOH and other government officers within their supervision area The total number of staff, therefore, varies with the coverage of the project, but the ideal ratio of staff to ... comprised of all the social, economic and environmental factors that facilitate or hinder the full health of children The adoption of key family practices does not assure the health of children Children ... shopkeepers Together, their practices often surpass the formal health system in terms of patient volume because they may be the most accessible sources of care at the community level These workers...
Ngày tải lên: 12/02/2014, 12:20
Tài liệu Addressing the Mental Health Needs of Young Children in the Child Welfare System pdf
... abused by their parent or parents What Type of Maltreatment Do Young Children in Child Welfare Face? ♦ Among young children, more than three-quarters of them are abused by their parent or parents ... by the parent or in the home During therapy sessions parents express thoughts and feelings about: their experiences as a child, the parent s hopes and expectations for the child s future, and the ... services to meet the “physical and mental well-being” of the children under their care.13 Only two states rated mental health for the children they served as a strength of their system.14 The most common...
Ngày tải lên: 12/02/2014, 19:20
Tài liệu No Child out of Reach Time to end the health worker crisis docx
... ask the right questions when a mother comes to me with her sick child I ask the name and age of the child, and which part of the body the pain comes from Doris says: “I gave birth to six children ... life-savers They are our most vital resource in improving the health and chances of survival of children, mothers and their families It is time for action Here, Save the Children makes the case ... from the adoption of the Global Strategy, the opportunity must be seized to accelerate the recruitment and training of more health workers to save millions of children’s lives ix No Child out of...
Ngày tải lên: 18/02/2014, 15:20
Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot
... major bands in e and f, while the numbers at the left are the pI values of standard proteins The arrow at the right represents the pI value of 6.84 calculated for the unmodified CLAP protein based ... destablization of the active site region of cathepsin L at higher than normal temperature and pH as suggested for cathepsin B [38] The increased stability of CL in the CLP complex is consistent with the ... proteins in the protein database The Conserved Domain Database of NCBI was screened with the protein coding sequence of clone of CLAP and the Fas I domains in the protein compared with 10 other fasciclin...
Ngày tải lên: 07/03/2014, 16:20
PMTCT STraTegiC ViSion 2010–2015: Preventing mother-to-child transmission of HIV to reach the UNGASS and Millennium Development Goals docx
... Team (IATT) on Prevention of HIV Infection in Pregnant Women, Mothers and their Children Guidance on global scale-up of the prevention of mother-to -child transmission of HIV: towards universal ... 430 000 children were newly infected with HIV in 2008, over 90% of them through mother-to -child transmission (MTCT) Without treatment, about half of these infected children will die before their ... efforts in the next few years will focus on responding to the needs of the ten countries with the highest number of pregnant women with HIV It is in these countries, where 75% of the need for...
Ngày tải lên: 14/03/2014, 09:20
Prevention of Mother-to-Child Transmission of HIV: Expert Panel Report and Recommendations to the U.S. Congress and U.S. Global AIDS Coordinator pot
... are part of the fabric of health care provided to women and children Conclusions The members of the Expert Panel emphasize the importance of maximizing the extent to which PMTCT, one of the most ... According to the Act, the objectives and the scope of the activities of the Expert Panel are to “provide an objective review of activities to prevent mother-to -child transmission of HIV” (human ... According to the Act, the objectives and the scope of the activities of the Expert Panel are to “provide an objective review of activities to prevent mother-to -child transmission of HIV” (human...
Ngày tải lên: 16/03/2014, 05:20
Child-friendly health care: the views and experiences of children and young people in Council of Europe member States doc
... of the survey which were then sent to the Council of Europe for processing A small number of children also undertook to complete the survey online All of these surveys were processed and so the ... about the appointment with the health care professional and the child s experience Firstly, it asked whether the child had time alone with the person they were seeing – 54.2% said that they did, ... their rights is clear To some extent, they are also aware of the unsatisfactory nature of delay and of cost and that the impact of these practical barriers to child- friendly health needs further...
Ngày tải lên: 17/03/2014, 17:20
Listening and Learning: the Ombudsman’s review of complaint handling by the NHS in England 2010-11 doc
... periods of great anxiety about the terminal illness of a loved one or the health of a young child In one case, the decision to remove the patient was made by the member of staff involved in the altercation ... from the 54 minute they pick up the phone to their GP surgery until the time they no longer need NHS care The types of issues highlighted in this report – communication and the handling of seemingly ... consider other courses of action the response They asked the The Practice also took Miss F’s Ombudsman for help Miss F said mother off their list even though 18 she had not been involved in the disagreement...
Ngày tải lên: 19/03/2014, 07:20
Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc
... present in the spleen of these mice For the determination of the number of PMM56 bacteria present in the spleen of these four mice, we thus chose a value of 50 CFU per spleen The average number of CFUs ... deciphering the complex biosynthetic pathways of DIMs and PGLs These efforts have led to the identification of more than 20 proteins required either for the formation or for the translocation of these ... that of DIM B, due to the reduction of the keto function of DIM B, followed by the methylation of the resulting hydroxyl group Thus, inactivation of the Rv2951c gene in M tuberculosis abolishes the...
Ngày tải lên: 23/03/2014, 09:20
Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases potx
... mechanisms [42,44] The study of the effect of pH on enzyme inactivation allows the calculation of the pKa of the His176 side chain involved in the inactivation reaction The rate of inactivation ... nitrogen atoms of the backbone of the residue preceding the catalytic Cys The conservation of this interaction is suggestive of its Fig The nal model of the clostripain catalytic domain The ribbon ... nonapeptide The nal residue of the resultant a-chain, Arg181, and the rst residue of the b-chain, Ala191, are also labelled (italics) The magenta colouring towards the bottom of the gure marks the position...
Ngày tải lên: 23/03/2014, 12:20
Addressing the Mental Health Needs of Young Children in the Child Welfare System pptx
... abused by their parent or parents What Type of Maltreatment Do Young Children in Child Welfare Face? ♦ Among young children, more than three-quarters of them are abused by their parent or parents ... by the parent or in the home During therapy sessions parents express thoughts and feelings about: their experiences as a child, the parent s hopes and expectations for the child s future, and the ... services to meet the “physical and mental well-being” of the children under their care.13 Only two states rated mental health for the children they served as a strength of their system.14 The most common...
Ngày tải lên: 24/03/2014, 00:21
GUIDANCE ON GLOBAL SCALE-UP OF THE PREVENTION OF MOTHER-TO-CHILD TRANSMISSION OF HIV potx
... GLOBAL SCALE-UP OF THE PRE VENTION OF MOTHER-TO -CHILD TR ANSMISSION OF HIV Table of contents GUIDANCE ON GLOBAL SCALE-UP OF THE PRE VENTION OF MOTHER-TO -CHILD TR ANSMISSION OF HIV Executive summary ... accelerating the scaling up of programmes, and tracking the global progress of the prevention of mother-to -child transmission of HIV and HIV care and treatment for children GUIDANCE ON GLOBAL SCALE-UP OF ... with HIV and their children and families GUIDANCE ON GLOBAL SCALE-UP OF THE PRE VENTION OF MOTHER-TO -CHILD TR ANSMISSION OF HIV Status of implementation of PMTCT programmes Since 1998, the international...
Ngày tải lên: 28/03/2014, 09:20
STATE OF THE DETROIT CHILD: 2010 pot
... of all Detroit children lived with a grandparent.30 Of these children, six in ten lived with a grandparent who was responsible for their care The poverty rate for grandparents in these grandparent-led ... navigating the financial insecurity of job loss, unemployment, foreclosure, or the simple stress of uncertain times, cannot hide the enormity of these events from their children Detroit’s children ... However, the percentage of children in the care 30.9% of their siblings rose from 14 percent to 16 9.7% Did Not Go To School/ percent and the percentage of children caring Felt Unsafe 20.8% for themselves...
Ngày tải lên: 30/03/2014, 03:20