... provide the flexibility and intuitiveness to allow for the formal definition of these types of relationships In the remainder of the text, we describe CRIT and apply it to three different types of ... of targets (Figure 2) Many of these cross patterns were between the physicochemical and composition properties of TFs and targets suggesting that the composition and evolutionary history of the ... notate the set of cross patterns between all the rows of the initial matrix and all the columns of the final matrix by I0 ↦In The specific cross pattern would be defined as i ↦ j On the first...
Ngày tải lên: 09/08/2014, 22:24
... Documents Creation of QE polica Responsibility Management Check on conformity No Process owner Yes Realization on paper HQU 01 - Chapterl 07 Internal communication Issued by Ing Berghofer Process owner...
Ngày tải lên: 22/12/2013, 02:18
Tài liệu Báo cáo khoa học: Molecular characterization of Arabidopsis thaliana PUF proteins – binding specificity and target candidates doc
... Scheme of the three-hybrid strategy used in the screen (B) Number of colonies identified in each step of the screen (C) Distribution of the 63 distinct sequences in relation of their position in the ... not the natural RNA target in Arabidopsis, the Box B sequence should mimic the authentic Arabidopsis targets On the other hand, APUM-7 was unable to bind to NRE, possibly as a result of the nonconservative ... substitution in the residue 13 of the repeat (APUM-2 ⁄ N fi H) and the protein APUM-7 with His fi Asn substitution in the same position (APUM7 ⁄ H fi N) with the NRE transcript The APUM-7 protein has the same...
Ngày tải lên: 18/02/2014, 06:20
Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx
... homologue of the mouse mSMOl, which is essentially a combination of the human isoforms and 4, had been identified The discovery of its existence in the mouse suggested the likelihood of a human ... homologue, and led us to pursue the identification of human SMO5 Furthermore, the implications of spermine oxidase activity in the nucleus prompted us to further investigate the localization of the human ... importantly, the surprising abundance of both active isoforms, SMO ⁄ PAOh1 and SMO5, in the nucleus, emphasizes the potential of these ROS-producing enzymes to either modulate cancer cell response to the...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: "Learning to Translate with Source and Target Syntax" pot
... root label of the source side of the rule, and ¬match f counts those where the labels not match • subst f →Y counts the number of substitutions X where the label of the source side of the substitution ... site is X and the root label of the source side of the rule is Y • matche , ¬matche , and subste →Y the same X for the target side • rootX,X′ counts the number of rules whose root label on the source ... structures and to reconcile the source and target trees with each other, rather than multiple restructurings of the training trees 4.3 Rule usage We then took a closer look at the behavior of the string-to-string...
Ngày tải lên: 07/03/2014, 22:20
ECONOMIC AND SOCIAL CONSEQUENCES OF DRUG ABUSE AND ILLICIT TRAFFICKING doc
... cost and value One indicator of the magnitude of the problem from an economic perspective are the estimates of the turnover of the global illicit drug industry Due to the clandestine nature of the ... drug problem The order of magnitude of the extent of the illicit drug problem should be established in the light of at least two of the unique characteristics of illicit drugs: first, they are all ... Development (UNRISD) and the United Nations University (UNU): in the comprehensive survey published at the outset of the project,11 the country studies themselves and the overview of their findings...
Ngày tải lên: 08/03/2014, 06:20
Báo cáo khoa học: "Bridging Morpho-Syntactic Gap between Source and Target Sentences for English-Korean Statistical Machine Translation" pot
... to align them with potential Korean function words and make the length of both sentences similar To insert the pseudo words, we need to decide: (1) the kinds of words to insert, and (2) the location ... measure the quality of translation When evaluating the proposed approach using within MOSES, the combined pseudo word insertion and syntactic reordering method outperforms the other methods The result ... length and word order contributes to lower the distortion and fertility parameter values Table analyzes the effect of individual techniques in terms of the null alignment ratio We discover that the...
Ngày tải lên: 17/03/2014, 02:20
Báo cáo khoa học: "Resolving Translation Ambiguity and Target Polysemy in Cross-Language Information Retrieval" potx
... explore the difficulties in the query translation of different languages, we gather the sense statistics of English and Chinese words Table shows the degree of word sense ambiguity (in terms of number ... shows the query translation of TREC topic 332 For the sake of space, only title field is shown In Table 3(a), the first two rows list the original English query and the Chinese query Rows and demonstrate ... co-occurrences Figure shows the number of relevant documents on the top 1000 retrieved documents for Topics 332 and 337 The performances are stable in all of the +weight (W) models and the enhanced CO restriction...
Ngày tải lên: 17/03/2014, 07:20
the effect of the hydrothermal treatment with aqueous naoh solution on the photocatalytic and photoelectrochemical propertiesof visible light-responsive TiO2thin films
... transformation of Vis-TiO2 thin film into the inactive TiO2 nanowires having high surface areas Fig shows the effect of the hydrothermal treatment on the XRD patterns of Vis-TiO2/Ti The intensity of the ... after hydrothermal treatment, Fig (a) XRD patterns of Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti and (b) the expanded XRD patterns of (a) (2u = 5–158) Fig XPS spectra of the Ti 2p (right) and Na 1s (left) ... where A represents Na and/ or H [17] Fig shows the Ti 2p and Na 1s XPS spectra of the VisTiO2/Ti before and after hydrothermal treatment The intensity of the Ti 2p peaks due to Ti4+ (Ti 2p3/2: 459...
Ngày tải lên: 20/03/2014, 13:11
financial statement analysis Abbott Laboratories and Target
... retail and credit card Target is well known for their operations in general merchandise and food items They owe their success to positive perceptions of the Target brand and they have built their ... in their stores, as well as in the merchandise they offer They want their customers to be satisfied in the quality of product they are purchasing By accomplishing this, Target hopes to retain their ... affected They owe their success to positive perceptions of the Target brand and they have built their reputation over many years of serving guests, team members, community and shareholders They too...
Ngày tải lên: 25/03/2014, 12:18
MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION docx
... adverse events and toxicities, and some are the enzymes and nuclear receptors of DM In our overall description of the disposition of the compound, interactions of the compound with these DM targets ... IN THE PROGRESSION OF DM years The meaning of the step increase in work at around 2010 in the figure will be discussed in the next section 1.3 NEXT STEP IN THE PROGRESSION OF DM The first three of ... elucidate the chemical structures of metabolites, augmented as necessary by NMR and synthesis of authentic standards However, detection of the presence of metabolites in a sample relied on the observation...
Ngày tải lên: 28/03/2014, 10:20
Báo cáo khoa học: Role of the plasma membrane leaflets in drug uptake and multidrug resistance ppt
... barrier and the epithelia lining the intestine and the nephrons It has been shown that the tight junctions pose a barrier to the movement of lipids between the outer leaflets of the apical and basolateral ... be the result of TMRM transfer from the cell surface further into the outer leaflet of the membrane or flip-flop across the membrane and residence in the inner leaflet of the membrane The observation ... cytoplasmic leaflet is the outcome of a balance between the rate of flip-flop across the membrane from the outer leaflet to the cytoplasmic leaflet of the plasma membrane and the release from the cytoplasmic...
Ngày tải lên: 29/03/2014, 08:20
For Medicare Advantage Plans, Medicare Advantage Prescription Drug Plans, Prescription Drug Plans, and 1876 Cost Plans ppt
... study: The source and date of the study Information about the plan sponsor’s relationship with the entity that conducted the study The study sample size and number of plans surveyed (unless the ... must add and a contract with the [state] Medicaid program” PDP sponsors must use one of the following statements below, verbatim, either in the text of the piece or at the end/bottom of the piece ... plans The scope of the term “marketing,” as used in the Medicare Statute at Section 1851(h) and 1860D-12(b)(3)(D)(12) of the Social Security Act (the Act) and CMS regulations, extends beyond the...
Ngày tải lên: 29/03/2014, 23:20
Báo cáo khoa học: "Combining Source and Target Language Information for Name Tagging of Machine Translation Output" ppt
... that of the previous token F11: ET result of the current token + ET result of the previous token F12: English NER result of the current token + that of the next token F13: ET result of the current ... that 38.14% of the names tagged in the target language and 40.5% of those in the source language not have a corresponding tag in the other language, which suggests that the source and target NER ... confidence The margin is the difference in log probability between the top tagging hypothesis and a hypothesis which assigns the name a different NE tag, or no NE tag We use this as the confidence of...
Ngày tải lên: 31/03/2014, 00:20
fragment based drug discovery and x-ray crystallography
... chip and ligands are allowed to flow past Ligands that bind to the protein cause changes in the reflectivity properties of the metal that are related to the mass of the ligand and the mass of the ... energy of ligand binding” is normally expressed in kilocalories per mole and the number of heavy atoms refers to the number of non-hydrogen atoms in the ligand Of course, the free energy of ligand ... to take off is because of all these problems Aggregation in particular was not really appreciated until the early part of this century In the absence of a clear understanding of some of these pitfalls,...
Ngày tải lên: 29/05/2014, 23:54
báo cáo hóa học: " Simultaneous buried object detection and imaging technique utilizing fuzzy weighted background calculation and target energy moments on ground penetrating radar data" potx
... AP and anti-tank (AT) mines given in Table The soil is dry and the dielectric constant value of soil is in the range of εr = 23 The diameters of the targets varies from 5.6 to 30 cm A total of ... approaching the target and departing from the target (see third rows of Figures 6c and 7c), in other words near to borders of the target in the scanning direction It will be shown in the next sections ... information of GPR B-scan data has a significant effect on the identification of the buried object and to train the operator themselves The following parameters are considered in the interpretation of...
Ngày tải lên: 21/06/2014, 00:20
Báo cáo hóa học: " Target estimation algorithm design using quantity data and target feature" pptx
... this article, the image processing is adopted to identify the target feature And then the computation algorithm will calculate the similarity between the image of measurement and image of existing ... filtering or the neighborhood processing [9] is conducted to reduce the noise and enhance the edge of target image (2) Segmentation: This step is to identify the contour of the targets from the image ... the image to extract the edges and then the wavelet Page of enhancement is selectively applied on the edges near the target boundaries (3) Coordinate transformation: The image of target may have...
Ngày tải lên: 21/06/2014, 03:20
DRUG DISCOVERY AND DEVELOPMENT – PRESENT AND FUTURE pptx
... of the major causes of attrition of a potential drug candidate is poor quality of the target The critical steps of target selection and validation require greater emphasis and incorporation of ... rates Related to the reconstruction of phylogenetic relationships is the determination of evolutionary rates and patterns The simplest way of estimating the nature and intensity of the selective ... classification, and pathogenesis of these conditions both in terms of ayurvedic and modern concepts According to this article there are 20 subtypes of Prameha due to the interaction of the three Doshas and...
Ngày tải lên: 27/06/2014, 17:20
Báo cáo khoa học: "SemiFDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma" potx
... metabolism of the tumor cells of the PET-negative component of the lesion The impact of PET/CT imaging on treatment planning was analyzed only by few authors without specific quantitative analysis of the ... on analysis of data EI and MB participated in the design of the study and contributed to write the manuscript All authors read and approved the final manuscript Competing interests The authors ... few of them tried to analyze the impact of PET/CT on radiotherapy treatment plans Trautmann et al reported that pre-treatment PET, in a series of 21 patients candidates for radiotherapy and chemotherapy,...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: " Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohort" ppt
... conception and design, acquisition of data, and analysis and interpretation of data; 2) have been involved in drafting the manuscript; and 3) have read and given approval of the final version of the ... indication of the necessity of increased patient education among IDUs regarding the medications they are using with emphasis on the importance of adherence The lack of data on viral drug resistance profiles ... history of injection drug use Patterns and trends of HAART use The longitudinal trends in the use of HAART by class of drug are depicted in Figure Both individuals with and without a history of injection...
Ngày tải lên: 10/08/2014, 05:20