genetic basis of sweet corn

... reflect the effects of large numbers of genetic variants of relatively small effect and, therefore, that genetic dissection of such traits will require investigation of samples of considerable size ... important form of corroboration of the role of a given gene in contributing to complex behavioral traits Demonstrations of the importance of pleiotropy in the genetic regulation of behavioral ... that a universal feature of complex behavior may be the contribution of numerous genetic variants of small effect may influence experimental design in human genetic studies of behavioral traits Furthermore,...

Ngày tải lên: 06/08/2014, 19:21

... introgression of a small fraction of the wild genome species while keeping the genetic background of the cultivated is a good mean to explore the largely untapped reservoir of useful alleles of interest ... application of molecular breeding approaches for the genetic improvement of cultivated peanut Up to date, few genetic linkage maps have been published in Arachis At the diploid level, three genetic ... due to the low level of polymorphism between cultivated peanut varieties, QTLs have been detected attesting of the interest of molecular breeding tools in genetic improvement of peanut Burow et...

Ngày tải lên: 12/08/2014, 03:21

... GENETIC BASIS OF SEVERE OBESITY: LEARNING FROM THE EXPERIMENTS OF NATURE DR LEE YUNG SENG MBBS, MMED (PAED MED), MRCP (UK), MRCPCH, FAMS A THESIS SUBMITTED FOR THE DEGREE OF PH.D DEPARTMENT OF ... of Cys28Phe and Leu37Phe 92 B) Co-segregation of C28F and L37F with overweight/obesity in 93 families 4-3 Structure of POMC and location of mutations 95 4-4 Sequence alignment of N-terminus of ... genes of this cohort were screened by direct sequencing The POMC gene of more than 900 DNA samples from the Genetics of Obesity Study (GOOS) (Cambridge, UK) were screened using a combination of...

Ngày tải lên: 11/09/2015, 09:02

... impact of a family history of diabetes; to further assess the genetic basis of type diabetes, we next examine the contribution of recently identified novel T2DM susceptibility loci on the risk of ... environmental factors) are most likely the cause of familial aggregation of diseases 7.3 THE COMPLEXITY OF THE GENETICS OF TYPE DIABETES Genetic studies of diseases have traditionally relied on two ... use of linkage analysis in genetic studies of rare, monogenic forms of diabetes, such as maturity-onset diabetes of the young (MODY) have been relatively successful in identifying the aberrant genetic...

Ngày tải lên: 14/09/2015, 08:48

... Preface The purpose of The Molecular Basis of Plant Genetic Diversity is to provide a glimpse into the dynamic process of genetic variation by presenting the thoughts of some of the scientists ... detection of genetic variation/diversity has greatly enhanced studies of evolution There is The Molecular Basis of Plant Genetic Diversity no doubt that genetic variation influences the fitness of individuals, ... genes of value for plant improvement Furthermore, knowledge of population structure of genetic resources is necessary for the development of strategies for appropriate conservation of genetic...

Ngày tải lên: 28/06/2014, 11:20

... proteins as markers of the genetic diversity in sweet holm oak MATERIAL AND METHODS Samples of acorns from 40 holm oak trees collected from the principal distribution regions of this species in ... 34.8% of total genetic diversity The proportion of genetic diversity found among the holm oak populations evaluated (Gst = 35.8%) was similar to the data obtained in other Fagaceae such as sweet ... Table Frequencies of each band in 120 acorns and populations of holm oak Zone Band Acorn (n = 120) Population (n = 8) 82.5 100.0 78 65.0 100.0 3C 111...

Ngày tải lên: 07/08/2014, 10:22

... reached a consensus on all of the items Data extracted from these articles included the first author’s name, year of publication, country of origin, ethnicity, number of cases and controls, genotype ... DSTPLAN4.2 software, in order to assess the probability of detecting an association between RANTES polymorphisms and asthma at the 0.05 level of significance, assuming a genotypic risk of 2.0 and ... located in epithelial cell of the mouth throat or lungs and adenocarcinoma is composed of cells of glandular tissue Over the past decades, many changes in the prevalence of esophageal cancer have...

Ngày tải lên: 25/10/2012, 11:40

... material and preparation of sweet potato leaf extract Fresh sweet potatoes (Ipomoea batatas (L) Lam) leaves were collected after the classification made by Department of Botany, Vietnam National ... Development of HFD-fed and STZ-induced type diabetic mice After weeks of dietary manipulation, a subset of the mice from each dietary group was injected intraperitoneally (i.p) STZ with dose of 120mg ... effect of the EtOAc fraction was 25.74%, higher as compared to other fractions 3.4 Effect of ethyl acetate fraction on lipid parameters of obese-diabetic mice Table Hypolipidemic effect of ethyl...

Ngày tải lên: 12/02/2014, 17:20

... molecular mode of action of glyphosate and the molecular basis for glyphosate resistance Structure and function of EPSPS EPSPS catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate ... however, was devoid of substrate or inhibitor, and consequently did not reveal the nature of the active site or the mode of action of glyphosate A decade later, the crystal structure of EPSPS was determined ... of the carbon–nitrogen bond of glyphosate, yielding AMPA and glyoxylate without production of hydrogen peroxide (Fig 3A) The authors proposed a mechanism that involves the reduction of FAD cofactor...

Ngày tải lên: 14/02/2014, 14:20

... phosphorylation state of their proteins, thereby changing the amount and localization of Bcl-2 family members However, each type of cancer has its own way of disrupting the balance of the networks of signaling ... associated with stimulation of ERK1 ⁄ and Pak1 pathways, gefitinib might lead to inhibition of invasiveness of human cancer cells through the inhibition of ERK1 ⁄ and Pak1 The use of gefitinib in cells ... inhibition of Akt- and ERK1 ⁄ 2-dependent pathways eventually change the expression level of one or more of these Bcl-2 family members Bad Bad is one of the ‘death-promoting’ members of the Bcl-2...

Ngày tải lên: 16/02/2014, 09:20

... Overlay of 1H,15N-HSQC spectra at 300 K of NarG(1–28) peptide in the absence (black trace) and in the presence (orange trace) of molar ratio of NarJ Fig S2 Overlay of 1H,15N-HSQC spectra at 300 K of ... Fig Ensemble of the backbone traces of the 20 lowest energy conformers of the solution structure of (A) NarG(1–15) and (B) NarG(1–28) second site) The measured enthalpy is the sum of two terms: ... varied by nearly a factor of 10 between the two subpopulations, i.e koff = 3.2 ± s)2 for the minor species of high affinity and koff = 1.9 ± s)1 for the major species of lower affinity Overall,...

Ngày tải lên: 16/02/2014, 14:20

... a large part of what there was of it without attracting attention Nobody seemed to think of a corner Most of all in his favor was the man himself His skill was thegrowth of years of experience, ... best-intentioned office boy in the world." "It's symbolic," said Sponley, laughing "It's the exact type of the ancient regime of Bagsbury and Company All the rest of the furniture of the bank is of the ... strongest reason of all his mouth and something in the inflection of his voice reminded her of her mother Jack Dorlin's disgust when he heard of Dick's decision quite outran his power of expression...

Ngày tải lên: 17/02/2014, 19:20

... those of atheism, because of their rejection of the gods of Greece and Rome; of immorality, because of the secrecy and mystery of their meetings, and cannibalism, because of their doctrine of the ... not of certainty, but of mere opinion And this estimate of the function of philosophy with respect to theological truth, which the Fathers worked out on the basis of the concrete example of the ... the truth, but each only from one point of view, and on the basis of only one method of approach The conclusions of each were the result of a process of more or less complete abstraction, and...

Ngày tải lên: 21/02/2014, 08:20

... turned out 30 In All Kinds of Weather N E B R A S K A , I O WA S TAT E – N O V E M B E R , One of the most often repeated axioms from the Of cial Treasury of Hokey Cornhusker State Sayings is ... On Saturday afternoons, the Cornhuskers are more than a pack of muscle-bound college kids running around in colorful padding They’re emblematic of us, of our way of life, and through their wins ... pursuit of as many Benjamins as possible, narrowed the Cornhusker broadcasting field to one originating station in an exclusive deal – kfor or klin out of Lincoln, or wow or kfab out of Omaha...

Ngày tải lên: 22/02/2014, 00:20

... Department of Internal Medicine, University of Cincinnati School of Medicine and Cincinnati VA Medical Center, Cincinnati, OH, USA Bruce C Trapnell, MD Department of Pediatrics and Department of Internal ... WA of Pathology, Seattle Children’s Hospital, Jean M Elwing, MD, Department of Internal Medicine, University of Cincinnati School of Medicine, Cincinnati, OH Andrew P Fontenot, MD, Department of ... W Kinder, MD, Department of Internal Medicine, University of Cincinnati School of Medicine, Cincinnati, OH Michael R Knowles, MD, Department of Medicine, University of North Carolina, Chapel...

Ngày tải lên: 05/03/2014, 23:20

... (3) elucidation of the chemical basis of heredity, the molecular basis of disease has been addressed in the context of how mutations affect the structure, function, or regulation of a gene or its ... analysis of the human genome has enabled detection of genome changes heretofore not observed because of technology limitations Whereas agarose gel electrophoresis enables detection of changes of the ... BEAUDET, MD • Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX WEIMIN BI, PhD • Department of Molecular and Human Genetics, Baylor College of Medicine, Houston,...

Ngày tải lên: 05/03/2014, 23:20

... different species [23–25] The success of the series of studies shows that the stable framework structure of Fv enables the transfer of function by means of CDR replacement Barbas et al first designed ... Functionalization of small scaffold proteins by replacing a loop of the scaffold protein with a CDR loop of antibody fragments (A) Replacement of the candidate location in NCS for grafting with the CDR loop of ... grafting the CDR loop of the single variable heavy chain of a heavy-chain camel antibody (VHH) (Fig 1B) by comparing topologies between VHH and NCS (Fig 2A); grafting of the CDR loop of antilysozyme...

Ngày tải lên: 06/03/2014, 11:20

... characterizations of the mutant forms of the Tus protein, many aspects of the mechanism of replication fork arrest at Tus-Ter complexes have been determined This and a brief description of the current state of ... activation domain of Gal4 of yeast (pGAD424-X) A suspected interacting Genetic Manipulation of DNA and Protein – Examples from Current Research Fig Crystal structure of Tus-Ter complex of E coli and ... structure of the cofactor binding-site of Hfx mediterranei GlcDH (Fig 6) indicates the spatial location of the residues mutated here and the interaction of R207 and R208 with the 2’-phosphate group of...

Ngày tải lên: 06/03/2014, 23:20

... analysis of a purified GPI-anchorless soluble version of the mutant protein The Kcat ⁄ Km value of the mutant TNSALP was less than one-tenth of the Kcat ⁄ Km value of the soluble form of the wild-type ... compilation ª 2008 FEBS 2735 Molecular basis of perinatal form of hypophosphatasia 10 11 12 13 14 15 16 17 18 19 N Numa et al establishment of a model of infantile hypophosphatasia Dev Dyn 208, ... containing the SV40 early promoter [11] Shortage of a precursor of GPI in the endoplasmic reticulum may be one of the reasons why a small but significant fraction of the wild-type TNSALP forms the aggregate...

Ngày tải lên: 07/03/2014, 05:20

... code an other semantic role – cause – in the case of verbs of existence (Table 2) It is important to note that we not dispose of a preliminary list of semantic roles To avoid arbitrary Com is for ... analysis of verb clusters We define well-founded verb classes on the basis of semantic role matrices These semantic roles can be filled in a sentence by casemarked NPs Therefore, evaluation of automatically ... representation of verbs and the clustering process were carried out based on (Schulte im Walde, 2000) The data to be compared were the maximum likelihood estimates of the probability distribution of verbs...

Ngày tải lên: 08/03/2014, 03:20