genetic basis of biological sexuality
Báo cáo y học: "Genetic polymorphism of p53, but not GSTP1, is association with susceptibility to esophageal cancer risk – A Meta-Analysis"
... reached a consensus on all of the items. Data extracted from these articles in-cluded the first author’s name, year of publication, country of origin, ethnicity, number of cases and con-trols, ... power of the selected studies by using the DSTPLAN4.2 software, in order to assess the probability of detecting an association between RANTES polymorphisms and asthma at the 0.05 level of significance, ... located in epithelial cell of the mouth throat or lungs and adenocarcinoma is composed of cells of glandular tissue. Over the past 5 decades, many changes in the prevalence of esophageal cancer...
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The Emergence of Biological Value
... it is often claimed (e.g., Depew and Weber 1998) that the nor-mativity of biological functions can be fully naturalized in terms of Wright’s(1998) analysis, in which a function is a part of a ... sense. Of course, science often looks to history to explain how the present state of a system came into being, but the present causal powers of a systemmust nevertheless be explicable in terms of ... stability of the oscillator.This dynamical interpretation of semantic information provides us with anew physical picture of the cognitive component of adaptive functionalaction.Most, if not all, of...
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Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc
... molecular mode of action of glypho-sate and the molecular basis for glyphosate resistance.Structure and function of EPSPSEPSPS catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate ... 4% of thetotal soluble protein content of the cell [48].Fig. 3. Microbial mechanisms of glyphosatedegradation. (A) Two principal pathways of glyphosate degradation are known.Top: cleavage of ... however, was devoid of substrate or inhibitor,and consequently did not reveal the nature of theactive site or the mode of action of glyphosate. A dec-ade later, the crystal structure of EPSPS was...
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Tài liệu Handbook of Clinical Sexuality for Mental Health Professionals docx
... have a high prevalence of sexual dysfunction,some of which is medication-induced, some of which is illness-induced, and some of which issimply part of the difficulties of living.4. El-Defrawi, ... my partner? HowHandbook of Clinical Sexuality for Mental HealthProfessionalsJeffrey W.Janata, PhD is Assistant Professor in the Department of Psychiatry andDirector of the Behavioral Medicine ... of the Department of ForensicMedicine in the University of Ulm in GermanyS.Michael Plaut, PhD is Assistant Dean for Student Affairs and Associate Professor of Psychiatry at the University of...
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Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx
... phos-phorylation state of their proteins, thereby changingthe amount and localization of Bcl-2 family members.However, each type of cancer has its own way of disrupting the balance of the networks of signalingcascades ... with stimulation of ERK1 ⁄ 2 andPak1 pathways, gefitinib might lead to inhibition of invasiveness of human cancer cells through the inhibi-tion of ERK1 ⁄ 2 and Pak1. The use of gefitinib in cellswith ... inhibi-tion of Akt- and ERK1 ⁄ 2-dependent pathways eventu-ally change the expression level of one or more of these Bcl-2 family members.BadBad is one of the ‘death-promoting’ members of theBcl-2...
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Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf
... centre of geometry of the NarG(1–15) peptide. Onlythe best structures of each of the 10 best clusters are depicted(HADDOCK score). Surface residues of NarJT in brown form thebottom of the ... thecomplex by 10-fold, as judged by koff. The physiologicalchaperone cycle probably consists of the rapid binding of the N-terminus of the partner, regardless of whetherit is a twin-arginine signal ... completion of thematuration process of the partner. The nature of thesignal that may trigger dissociation of the complexremains unclear; however, we propose that a localperturbation of the hydrogen...
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Tài liệu The Basis of Early Christian Theism ppt
... not of certainty, but of mere opinion.And this estimate of the function of philosophy with respect to theological truth, which the Fathers workedout on the basis of the concrete example of the ... the truth, but each only from one point of view, and on the basis of only onemethod of approach. The conclusions of each were the result of a process of more or less completeabstraction, and ... scholar of the Church University Board of Regents from July, 1895, to thepresent time.End of the Project Gutenberg EBook of The Basis of Early Christian Theism, by Lawrence Thomas Cole*** END OF...
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Tài liệu Mesoscopic Model for Mechanical Characterization of Biological Protein Materials docx
... may affect the estimation of Young’s modulus of biological fibers.10 Further, for validation of our computational model for biological protein materials consisting of protein crystals, as shown ... illustration of biological protein materials composed of protein crystals. (a) cartoon of a fiber, made of protein crystals, under mechanical loading. (b) protein crystal lattices constituting the biological ... degree -of- fold, Q, is responsible for high yield stress of biological protein materials through breakage of hydrogen bond of β-sheet structural motif. For deeper understanding the role of native...
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Molecular Basis of Pulmonary Disease Insights from Rare Lung Disorders pdf
... theoccurrence of an outcome of interest. This might be a study of time until disease pro-gression or overall survival. In these types of study designs, it is the person-years of follow-up that ... PanosWhen you hear hoofbeats behind you, don’t expect to see a zebra.Theodore E. Woodward, MD, University of Maryland, Circa 1950 (1)Abstract The National Institutes of Health Of ce of Rare Diseases ... there are many different types of study designs; some of which require onlya fraction of the number of subjects required to the randomized controlled trial, whichis often considered the gold standard.Alternate...
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GENOMIC DISORDERS The Genomic Basis of Disease doc
... started his PHD on genetics of Alzheimerdisease, but because the families were still being sampled, he initially spent a lot of effort in22 Part II / Genomic Structure0.1% of human genetic disease, ... typical integrationis then finished off by the formation of a second-strand nick and integration of the end of thecDNA (Fig. 2A). However, significant portions of the events appear to complete ... genomicrearrangements.Most of the Alu–Alu recombination events are between nearby elements, generally spanningdistances of less than 50 kb and often only a few kb in length. There are also a number of cases of chromosomal...
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Báo cáo khoa học: Protein–protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information potx
... different species [23–25]. The success of the series of studies shows that the stable framework structure of Fv enables the transfer of function by means of CDRreplacement.Barbas et al. first ... theCDR loop of the single variable heavy chain of aheavy-chain camel antibody (VHH) (Fig. 1B) by com-paring topologies between VHH and NCS (Fig. 2A);grafting of the CDR 3 loop of antilysozyme ... sequence of charyb-dotoxin with one of toxin a to express a new bindingfunction. Comparison of the X-ray crystal structuresbetween charybdotoxin and toxin a showed the struc-tural resemblance of...
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GENETIC MANIPULATION OF DNA AND PROTEIN – EXAMPLES FROM CURRENT RESEARCH pptx
... characterizations of the mutant forms of the Tus protein, many aspects of the mechanism of replication fork arrest at Tus-Ter complexes have been determined. This and a brief description of the current ... is a problem word in genetics for some people. This volume has another purpose - to be accessible to those who fear the power of genetics. Those of us who know modern genetics understand that ... complete understanding of genetics, humankind will reach an important new stage. Humans will be able to change their own genes. Of course, evolution will continue to be an agent of genetic change;...
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Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx
... Left lane:14C-methylated protein markers of 200, 97.5, 66, 46 and 30 kDa, from the top of the gel.N. Numa et al. Molecular basis of perinatal form of hypophosphatasiaFEBS Journal 275 (2008) ... gel.Molecular basis of perinatal form of hypophosphatasia N. Numa et al.2730 FEBS Journal 275 (2008) 2727–2737 ª 2008 The Authors Journal compilation ª 2008 FEBSMolecular basis of perinatal ... GPI-anchorless solubleversion of the mutant protein. The Kcat⁄ Kmvalue of the mutant TNSALP was less than one-tenth of theKcat⁄ Kmvalue of the soluble form of the wild-typeenzyme, indicating...
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Báo cáo khoa học: "Clustering Hungarian Verbs on the Basis of Complementation Patterns" pot
... the Basis of Complementation PatternsKata G´aborDept. of Language TechnologyLinguistics Institute, HAS1399 Budapest, P. O. Box 701/518Hungarygkata@nytud.huEnik˝o H´ejaDept. of Language ... on the basis of their complementationpatterns, yielding a set of basic classes andhints about the features that determine ver-bal subcategorization. The resulting classesserve as a basis for ... attempt tocluster verbs on the basis of their syntactic proper-ties with the further goal of identifying the seman-tic classes relevant for the description of Hungarianverbs’ alternation...
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Báo cáo khoa học: "Shallow parsing on the basis of words only: A case study" pptx
... entry of a word than the identity of the word itself, e.g. MAJOR and other HEAD fea-tures in (Pollard and Sag, 1987). In the early days of statistical parsers, POS were explicitly and often ... (2000) give anoverview of the CoNLL shared task of chunking.The types and definitions of chunks are identical tothe ones used here. Training material again consists of the 9000 Wall Street ... addition, theeffect of our mix of sentences from different corporaon top of WSJ is not clear.Ferro et al. (1999) describe a system for find-a different category, as in the case of VP/S-NOM inthe...
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- free nucleotides in living cells play important roles in a variety of biological reactions
- department of biological sciences
- the basis of bills of exchange
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- ecological basis of agroforestry
- kinetics of biological catalysts
- crossword puzzle for biological basis of genetics 1
- biological basis of genetic engineering
- biological basis of genetically modified animals
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