Tài liệu Molecular Neurobiology of Alzheimer Disease and Related Disorders doc
... clearance Curcumin increases CD11c in phagocytes and faciliates clearance Synapse and neuron dysfunction and loss Curcumin suppresses A-induced loss of NR2B and PSD-95, synaptic markers essential for ... Frautschy SA: Estrogen (E 2 ) and glucocorticoid (Gc) effects on microglia and A clearance in vitro and in vivo. Neurochem Int 2001;39:435–448. 80 Hussain MS, Chandrasekhara N: Effect on curcumin ... antibody and anti-HMGA1, followed by staining with Cy3- and FITC-conjugated secondary antibodies, respectively, and analyzed by immunofluo- rescence microscopy. Endogenous HMGA1 (green) and SC35...
Ngày tải lên: 14/02/2014, 17:20
Tài liệu Parkinson’s Disease and Related Disorders docx
... the alpha- and beta frequency bands. For instance, in parkinso- nian monkeys and patients, oscillatory burst- ing typically emerges in both the 3–8 Hz band, and a power spectral band around 10 ... honour outstanding scient ists and clinicians, Toshiharu Nagatsu, Yoshikuni Mizuno, Japan (Award of the WFN Research Group on Parkinsonism and Related Disorders) , Saskia Biskup, Germany and Andrew ... to practice and treatment strategies. The guided poster tours allowed exchange of scientific ideas and shed light on new findings in etiology, diagnosis and treatment of PD and related disorders. A...
Ngày tải lên: 14/02/2014, 17:20
Tài liệu Intracellular Traffic and Neurodegenerative Disorders pptx
... Aβ generation; and (4) sorting of APP and/ or its α -and -carboxyl-terminal fragments (C83 and C99, respectively) toward the trans-Golgi network is under the influence of presenilins and the VPS35/retromer. ... sorting and neurotransmission (Mostov and Cardone 1995; Clague and Urbe 2001; Bonifacino and Traub 2003). A striking ex ample ∗ Reprinted in part from Neuron (2006), with permission. S. Gandy Mt ... site-2 (S2P) metalloprotease (Brown and Goldstein 1999), the GxGD-type aspartyl proteases (Haass and Steiner 2002) and the rhomboid serine proteases (Lemberg and Freeman 2007) (Fig. 1). ICLIP turned...
Ngày tải lên: 14/02/2014, 17:20
Tài liệu PEDIATRIC NASAL AND SINUS DISORDERS doc
... Sports and Exercise Medicine, edited by S. C. Wood and R. C. Roach 77. Endotoxin and the Lungs, edited by K. L. Brigham 78. The Mesothelial Cell and Mesothelioma, edited by M C. Jaurand and J. ... and Sinus Disorders, edited by Drs. T. M. Sih and P. A. R. Clement, been included in the series. This work not only presents a comprehensive review of the physiology of the nose, and of its disorders, ... Kempen, and Bachert Over the years, the series of monographs Lung Biology in Health and Disease has presented many volumes and chapters in which the biology and pathology of the nose and the...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Photoreceptor Sensory Cilium and Associated Disorders pptx
... distribution, and reproduction in any medium, provided the original work is properly cited. Photoreceptor Sensory Cilium and Associated Disorders Linjing Li, Ozge Yildiz, Manisha Anand and Hemant ... diseases, and photoreceptor degeneration and blindness [6-7, 16-18]. 2. Photoreceptor sensory cilium and its components In photoreceptors (rods and cones), cilia are highly specialized and modified ... blindness and loss of peripheral vision (due to rod death) in the Photoreceptor Sensory Cilium and Associated Disorders 55 [22] Insinna, C. and Besharse, J. C. Intraflagellar transport and the...
Ngày tải lên: 19/02/2014, 22:20
Tài liệu Photoreceptor Sensory Cilium and Associated Disorders docx
... links and to further delineate the roles of TZ proteins in regulating protein trafficking and photoreceptor OS development and function. Author details Linjing Li, Ozge Yildiz, Manisha Anand and ... distribution, and reproduction in any medium, provided the original work is properly cited. Photoreceptor Sensory Cilium and Associated Disorders Linjing Li, Ozge Yildiz, Manisha Anand and Hemant ... diseases, and photoreceptor degeneration and blindness [6-7, 16-18]. 2. Photoreceptor sensory cilium and its components In photoreceptors (rods and cones), cilia are highly specialized and modified...
Ngày tải lên: 19/02/2014, 23:20
PARKINSON''''S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN potx
... RELEVANT TO MOVEMENT DISORDERS CENTRAL NERVOUS SYSTEM SIGNS HYPER KINETIC DISORDERS FINAL COMMENTS SELECTED READING 1 3 From: Parkinson’s Disease and Movement Disorders: Diagnosis and Treatment Guidelines ... ground (steppage gait) resembles certain dystonic gaits with dystonic exaggeration of knee and hip flexion Proprioceptive deficits affecting gait • Resembles cerebellar ataxic gait Tremor (occurs ... Practice: Application and Interpretation, by S YDNEY LOU BONNICK, 1998 Diseases of the Liver and Bile Ducts: Diagnosis and Treatment, edited by GEORGE Y. WU AND JONATHAN ISRAEL, 1998 The Pain Management Handbook:...
Ngày tải lên: 05/03/2014, 23:20
LifeOut of Focus Alzheimer’s Disease and Related Disorders ppt
... successful, and well respected in her community. At home, she and her husband especially enjoyed spending time with their six grandchildren. There, Helen could put numbers and finances and tax forms ... the United States and in several foreign countries. 14 LIFE OUT OF FOCUS: ALZHEIMER’S DISEASE AND RELATED DISORDERS The children were all grown and on their own when her husband retired from the ... stillness. And silence. Helen and Mary died within a month of each other, two years after 20 LIFE OUT OF FOCUS: ALZHEIMER’S DISEASE AND RELATED DISORDERS Late one night, police found Helen wandering...
Ngày tải lên: 05/03/2014, 23:20
PET in the Evaluation of Alzheimer’s Disease and Related Disorders docx
... respectively; and my family—my wife Wei, our kids, our parents Donna and Robert and Pei and Robert, and my sibs Anne, Beth, and Mikhael, whose contributions of friendship, love, understanding of ... patients and asking questions to gather information about a patient’s behavior and appearance, ambulation and move- ment, mood and affect, speech, thought processes and content, insight and judgment, ... disease (AD) and other dementias; and also addresses how to identify candidates for a dementia evaluation, discusses the role of neuroimaging in a clinical dementia evaluation, and identifies...
Ngày tải lên: 05/03/2014, 23:20
An Atlas of PARKINSON’S DISEASE AND RELATED DISORDERS pdf
... Kayser–Fleischer rings, and no evidence of abnormal copper accumulation. The clinical features are variable and include an encephalopathic syndrome, various movement disorders and a myelopathy. The ... loss in the caudate and putamen and, to a lesser extent, in the globus pallidus and cerebral cortex. Macro- scopically the brain is shrunken with widening of the cortical sulci and dilatation of ... Associate Professor of Neuropathology and Neurosurgery, NYU Medical Center, New York, and Professor M.H. Mark, The University of Medicine and Dentistry of New Jersey, New Jersey Figures 20 and 34, from Dr D. Miller,...
Ngày tải lên: 14/03/2014, 22:20
An Illustrated Pocketbook of Parkinson''''s Disease and Related Disorders pot
... in the form of urinary urgency and occasional incontinence) and a variety of eye signs, including broken pursuit movements, and some limitation of upward gaze and convergence. A positive glabellar ... putamen, thalamus and cerebellum. A more focal cerebral insult in the perinatal period may also be associated with focal dystonia and corresponding imaging abnormalities (Figures 55 and 56). Figure ... condition spreads and accentuates. Typically, the foot tends to invert and plantar flex, while involvement of the trunk produces a variety of abnormal body postures (Figures 50 and 51). Muscle...
Ngày tải lên: 14/03/2014, 22:20
RESPIRATORY HEALTH EFFECTS OF PASSIVE SMOKING: LUNG CANCER AND OTHER DISORDERS ppt
... standard deviation, and maximum and minimum nicotine values measured in different indoor environments with smoking occupancy 3-23 3-5 Mean, standard deviation, and maximum and minimum concentrations of ... SMOKING: LUNG CANCER AND OTHER DISORDERS Major funding for this report has been provided by the Indoor Air Division, Office of Atmospheric and Indoor Air Programs Office of Health and Environmental ... 5/6: Kenneth G. Brown 3 Chapter 7: Fernando D. Martinez 4 Chapter 8: Fernando D. Martinez and Steven P. Bayard Appendix A: Kenneth G. Brown, Neal R. Simonsen, and A. Judson Wells 3 3 Appendix B:...
Ngày tải lên: 15/03/2014, 01:20
Fatty Liver Disease: NASH and Related Disorders ppt
... steatosis and steatohepatitis III: peroxisomal β-oxidation, PPARα, and steatohepatitis. Am J Physiol Gastrointest Liver Physiol 2001; 281: G1333–9. Fatty Liver Disease: NASH and Related Disorders Edited ... of Gastroenterology, MetroHealth Medical Center and Schwartz Center for Metabolism and Nutrition, Cleveland, OH 44102-1998, USA EPIDEMIOLOGY AND RISK FACTORS OF NASH 35 97 Navarro VJ, St. Louis ... obesity and type 2 diabetes mellitus in the USA and elsewhere, clinicians and investigators have developed an appreciation for the link between non-alcoholic fatty liver disease (NAFLD) and hepatic...
Ngày tải lên: 22/03/2014, 16:20
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