gait disorders and balance disturbances in parkinsons disease

Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx

Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx

Ngày tải lên : 19/02/2014, 18:20
... or unfavorable, depending on the disease. As a case in point, formation of huntingtin-containing inclusion bodies in Huntington’s disease encourages cell survival, whereas monomers and small inclusion bodies ... deficient in desmin, again demonstrating inclusion body construc- tion independent of intermediate fialments [62]. Inter- estingly, inclusion body formation is slowed by aB-crystallin, Hsp27 and HspB8, ... aA- crystallin requires this domain [66]. Attachment of R116C aA-crystallin to Hsp27 and aB-crystallin increases in comparison to wild type, while binding to cC-crystallin and bB2-crystallin decreases....
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Tài liệu Sport and Physical Activity in Children with Congenital Heart Disease ppt

Tài liệu Sport and Physical Activity in Children with Congenital Heart Disease ppt

Ngày tải lên : 12/02/2014, 19:20
... expected in this setting. Recommended types of exercise include interval training at moderate intensity, e.g., ball games and running games, or moderate stamina training. Their afterload reducing ... surgery/interventions (including ablations) Group 1 Patients after cardiac surgery/interventions (including ablations) 1.1 Without remaining findings (complete correction) 1.2 With minimal findings 1.3 ... requiring surgery 0 No sports A No (remaining) cardiac defects 1.1 Unlimited B Mild (remaining) findings 1.2; 2.1; 2.2; 2.3; 2.4; 4.2 Unlimited C Clinically significant (remaining findings) 1.3;...
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Tài liệu Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980--2010 docx

Tài liệu Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980--2010 docx

Ngày tải lên : 15/02/2014, 04:20
... gastro-intestinal diseases, injuries and poisoning, and infectious and parasitic diseases in the last three decades, in Portugal [10]. Since some of these causes of death are more common in the ... in 2004, surpassed by infectious and parasitic diseases, perinatal conditions and unintentional injuries. Age-standardized mortality rates from CVD have been declining for several decades in ... significant change in the log-linear slope of the trend (joinpoints) [14]. The analysis starts with the minimum number of joinpoints (no joinpoints corresponds to a straight line), and tests whether...
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Sleep Disorders and Neurologic Diseases potx

Sleep Disorders and Neurologic Diseases potx

Ngày tải lên : 05/03/2014, 23:20
... recognized sponsoring specialties and who are certified in Sleep Medicine. Faculty should be available to participate in consultation and teaching in disciplines related to Sleep Medicine including cardiology, ... disorders, movement disorders, multiple sclerosis, neurodegenerative disorders, headaches, and trau- matic brain injury. They should also possess in- depth knowledge of intrinsic brain sleep disorders ... Their stud y included both institutionalized and community-dwelling individuals. Espie et al. found decreased REM sleep, an increased REM sleep latency (172.5 minutes), and “indiscriminate” nonREM...
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Gait Disorders Evaluation and Management docx

Gait Disorders Evaluation and Management docx

Ngày tải lên : 05/03/2014, 23:20
... Chapters 3 and 4) have not been applied widely in clinical assessments of older adult balance and gait disorders. Instead, a set of functional gait and balance tasks (which includes gait- related ... book is to provide clinicians, thera- pists and others treating gait disorders with an understanding of the mechan- isms underlying gait disorders and how to best manage these disorders. To a large ... Classifications of Gait Patterns Using Gait Analysis in CP . . . . 251 III. Gait Analysis in PD and HD . . . . 254 IV. Huntington’s Disease . . . . 257 xii Contents III. Static Balance and PN . . ....
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Báo cáo khoa học: Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies pot

Báo cáo khoa học: Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies pot

Ngày tải lên : 06/03/2014, 09:22
... recognition in the normal splicing process [55]. First, U1snRNP binding to an intronic splicing processing element has been found to inhibit pathological pseudoexon inclusion in intron 20 of ... 847 MINIREVIEW Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies Ashish Dhir and Emanuele Buratti International Centre for Genetic Engineering and ... splice- supporting intronic mutation in the last bp position of a cryptic exon within intron 6 of the CYBB gene induces its incorporation into the mRNA causing chronic granulomatous disease (CGD)....
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TMJ Disorders and Orofacial Pain The Role of Dentistry in a Multidisciplinary Diagnostic Approach pptx

TMJ Disorders and Orofacial Pain The Role of Dentistry in a Multidisciplinary Diagnostic Approach pptx

Ngày tải lên : 06/03/2014, 11:20
... Fibrosis and Bony Ankylosis 283 Tumors in the Temporomandibular Joint Region 284 Joint Disorders Articular Surfaces 286 Joint Disorders Articular Disk 287 Joint Disorders Bilaminar Zone and Joint ... of the dentist in diagnosing and treating pain in the head and neck region increasingly obscure rather than more clear. In the academic debate concerning the etiology—pre- dominantly psychological ... receptors through inflammation or rupture, resultina in Dain. 8 Primary Dental Evaluation Findings in the Teeth and Mucous Membrane The intraoral evaluation includes in particular: • careful...
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Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b potx

Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b potx

Ngày tải lên : 07/03/2014, 15:20
... that interfacial protein–protein interactions between the hinge region of ISP and the extramembranous cd2 helix of cytochrome b are important for maintaining the structure of the hinge region and, ... substrate and the inherent partioning of quinol into the Q o site. The Fig. 3. Steady-state level of the iron–sulfur protein (ISP) in G167E. Immunoblots of denaturing gels, loaded with 40 lg of protein ... glutamate (in yeast or humans) may affect the structure of the hinge region, resulting in a hindered move- ment and enzyme instability. As suggested previously for a yeast mutant with a +1 alanine insertion...
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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Ngày tải lên : 16/03/2014, 11:20
... including investigations in human tissues, and that this has implications for how to interpret the role of the stud- ied enzymes in health and disease. Results The distribution and relative intensity ... toxic isoquinolines such as salsolinol [23]. In line with the suggested role of ADHs and ALDHs in protection against toxic insults, mRNAs encoding these enzymes have previously been identified in tissues ... corresponding rat tis- sues show expression only in duodenum, colon and rectum. In both mouse and rat, Adh4 is found in the epithelial lining of upper GI tract including the tongue, esophagus and stomach,...
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Báo cáo khoa học: Nature, nurture and neurology: gene–environment interactions in neurodegenerative disease docx

Báo cáo khoa học: Nature, nurture and neurology: gene–environment interactions in neurodegenerative disease docx

Ngày tải lên : 16/03/2014, 19:20
... gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell 72, 971–983. 6 Young AB (2003) Huntingtin in health and disease. J Clin Invest 111, ... neurodegeneration in Huntington’s disease: a comparative study of cannabinoid, dopamine, adeno- sine and GABA (A) receptor alterations in the human basal ganglia in Huntington’s disease. Neuroscience ... made in identifying genetic factors contributing to PD in recent years [135]. Low concordance for clinical disease in monozygotic twins indicates environmental in uen- ces on PD [136], and the...
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