functional competencies of hr manager
Tài liệu Functional Specification of JPEG Decompression. and an Implementation for Free ppt
Ngày tải lên :
09/12/2013, 15:15
... benets of abstraction in a functional language.
This article assumes no knowledge of JPEG or any of its algorithms, nor of specialized functional
programming techniques. Basic knowledge of functional ... downsample the chrominance information to half its resolution. This immediately
alters the size of an image by a factor of
2
3
(two out of three components)
3
4
(three out of four
pixels are ... Human trees are used. Each of them is specied in the
header of the le as a list of lists. These lists contain the values that have codes of equal length.
The construction of the corresponding Human...
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Tài liệu Management of HR Systems/Practices pptx
Ngày tải lên :
18/01/2014, 15:20
... Management of HR Systems/Practices
This aspect of the skill set is critical to ensure organizational excellence, a spirit of pride and elan
in the organization, ... recruiting; deployment and development of resources; the building of
solid working relationships, the development of teams and people; and planning for the success
of the organization. This involves ...
Management of HR systems/practices involves skills in the following areas:
Development of People
"Development" in this context refers to the design and operationalization of systems...
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Tài liệu Physical health and functional ability of an elderly, population in Sri, Lanka doc
Ngày tải lên :
14/02/2014, 06:20
...
Years
of
life expectancy free
of
problems with
PADL
12.32
13.43
Years
of
LE
free of problems with all
ADL
7.81
8.33
%
of
total
LE
free
of
problems with
PADL
93.3
91.2
%
of
... females, years of
life expectancy free of problems with ADL
activities was relatively low for both genders
(Table 8).
Discussion
Identification of health problems and functional
ability of an elderly ... member of the household present at
the time of the interview was identified as an
"informant". At each interview where an
informant was present, assessment of the
informant of the...
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
Ngày tải lên :
15/02/2014, 01:20
... consequences
of having HPRT deficiency are an overproduction of
uric acid and elevated levels of PRPP [3]. Patients hav-
ing mutations resulting in partial HPRT deficiency
often suffer from gouty arthritis. ... elucidation of the structure of PRTFDC1
and the definition of its ligand binding specificity from
a large metabolome library provides an initial start
point for defining the molecular function of
PRTFDC1. ... solvent content of 56.4%. The asymmetric
unit contained two subunits. Data were collected at ID29
of the European Synchrotron Radiation Facility (Grenoble,
France) using a wavelength of 1.04 A
˚
....
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Tài liệu Báo cáo khoa học: Functional characterization of an orphan cupin protein from Burkholderia xenovorans reveals a mononuclear nonheme Fe2+-dependent oxygenase that cleaves b-diketones ppt
Ngày tải lên :
18/02/2014, 06:20
... resulting from cyto-
chrome c being reduced by superoxide in the course of the
reaction. The principle of the assay is that the presence of a
SOD inhibits the reduction of cytochrome c. This was ... three
nitrogen(oxygen) donor ligands at an average distance
of 1.92 A
˚
and three nitrogen(oxygen) donor ligands at
an average distance of 2.15 A
˚
, one of which was an
imidazole side chain of ... kinetics
and mechanisms of the reactions of iron(III) with b-dik-
etones. The formation of monoacetylacetoatoiron(III)
and the effect of copper (II) on the formation of
monothenoyltrifluoroacetonatoiron...
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Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc
Ngày tải lên :
18/02/2014, 14:20
... the dynamics and features of this protein.
Role of MCPIP in regulation of the endogenous
IL-1b transcript level
After identification of a PIN domain in the MCPIP by
use of bioinformatics, we decided ... transcript independently of the
presence of AREs (Fig. 6B, lanes 2 and 5). It is possible
that in the region located before the AREs, consisting of
343 bp of the 3Â UTR of the IL-1b transcript, ... present in the 3Â UTR of IL-6 mRNA [4,17]. The
presence of such a sequence may account for the degra-
dation of both types of IL-1b transcripts, with and with-
out AREs. The influence of MCPIP on the...
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Tài liệu Báo cáo khoa học: Structural and functional investigations of Ureaplasma parvum UMP kinase – a potential antibacterial drug target ppt
Ngày tải lên :
18/02/2014, 16:20
... and a hydrophobic interaction between
Thr131 and Phe133 (Fig. 3D). The central channel of
the hexamer is made up of two layers of electrostatic
forces on top of each other, with one layer rotated ... ratio of UpUMPK ⁄ phos-
phate of 25 ⁄ 1.
The effect of orthophosphate on enzyme activity
was examined. It was shown that phosphate inhibited
UpUMPK activity with an IC
50
value of 1 mm
(Fig. 7).
Functional ... neigh-
boring subunit (Fig. 8). The backbone of Asn140 and
the side chain of Thr138 also form hydrogen bonds to
the uracil base. Mutations of either Thr138 or Asn140
to Ala abolished GTP activation,...
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Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc
Ngày tải lên :
18/02/2014, 18:20
... integration of the Cartesian equations of
motion of a system with constraints: molecular dynam-
ics of n-alkanes. J Computat Phys 23, 327–341.
44 Koradi R, Billeter M & Wu
ă
thrich K (1996) ... The ability of polymeras-
es to use Mn
2+
instead of Mg
2+
as a required
cofactor is well established [25]. However, the bio-
chemical properties of polymerases are altered as a
result of replacing ... 8.6, 9.0 and 9.6). (B) Dependence of
Rep245 polymerase activity on metal ions. The results are the means of three independent experiments. (C) The dependence of polymerase
activity on the temperature...
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Tài liệu Báo cáo khoa học: Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase Investigations of the putative catalytic glutamate–arginine pair and of residues responsible for substrate specificity docx
Ngày tải lên :
19/02/2014, 02:20
... particular,
phosphorylation of dGuo was reduced markedly.
Structure of Dm-dNK-E52D in complex with dTTP
The structure of one of the mutants, E52D, was solved
using X-ray crystallography at a resolution of 2.5 A
˚
in
complex ... levels of phosphorylation expressed in rela-
tion to percentage dThd phosphorylation of the wild-type. Relative
phosphorylation expressed as a relation of the percentage of dThd
phosphorylation of ... quantitation of microgram quantities of protein util-
izing the principle of protein–dye binding. Anal Biochem
72, 248–254.
22 Knecht W, Bergjohann U, Gonski S, Kirschbaum B &
Loffler M (1996) Functional...
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Tài liệu Báo cáo khoa học: A functional polymorphism of apolipoprotein C1 detected by mass spectrometry docx
Ngày tải lên :
19/02/2014, 05:20
... (F) Peak ratios of lipoprotein isoforms. The ratio of
peak intensities for ApoC2 (m z ẳ 8915, n) to the sum of peaks of
ApoC1 was determined for fraction 1 and assigned a value of 1.0.
The peak ... value. Also shown are the relative ratios of the sum of peaks
from ApoC3 to the sum of peak intensities from ApoC1 (r) and
the ratios of several isoforms of ApoC3 (m z ẳ 8765 : 9713, des-
glycoApoC3-0 ... results). In contrast, functionally dif-
ferent proteins often give peaks of unequal intensity
because of unequal rates of biosynthesis, utilization, or
degradation. Variants of TTr that are associated...
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Tài liệu Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation ppt
Ngày tải lên :
19/02/2014, 16:20
... ng of FLAG-DEC1 expression vector and
50 ng of FLAG-BMAL1 expression vector resulted in
adequate levels of expression. The transcriptional activity
of FLAG-BMAL1, and the suppressive activity of ... Kato
1
1
Department of Dental and Medical Biochemistry, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan;
2
Department of Physiology, Hokkaido University Graduate School of Medicine, ... CLOCK/BMAL1 through com-
petition for binding to E-boxes and/or protein–protein
interactions of DECs with BMAL1 [ 7]. Furthermore, w e
recently demonstrated the existence of a novel autofeedback
loop...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx
Ngày tải lên :
20/02/2014, 01:20
... equation
that allows calculation of the concentration of mAb that
produces 50% of the inhibitory effect (IC
50
) [61].
Effect of anti-LBS mAbs on the activation of
plasminogen by fibrin- and cell-bound ... were starved of serum and then incubated
with varying concentrations of Glu-Pg (0–2 lm) and a fixed
concentration (0.75 mm final concentration) of CBS0065 in
a total volume of 100 lL of Ham-F12 medium ... Lysi-
ne ⁄ fibrin binding sites of kringles modeled after the
structure of kringle 1 of prothrombin. Proteins 3, 85–96.
20 Thorsen S (1975) Differences in the binding to fibrin of
native plasminogen and...
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Tài liệu Báo cáo khoa học: Mapping the functional domains of human transcobalamin using monoclonal antibodies pptx
Ngày tải lên :
20/02/2014, 01:20
... Specificity of monoclonal anti-(human transcobalamin) sera and their effect on the functional properties of transcobalamin. nd, not
done.
mAb
Epitope
cluster
Precipitation of
Apo-TC (%)
Precipitation of
Holo-TC ... significant part of TC, a
composite organization of the receptor recognition site
may be suggested, where its components come from
different parts of the protein. Reconstruction of the
functional receptor-binding ... maximal
mAb ⁄ heparin effect on the functional activ-
ity of TC. Arrows show the hypothetical
movement of the domains after attachment
of Cbl, see the main text.
Mapping of transcobalamin using antibodies...
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Tài liệu Báo cáo khoa học: Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I pdf
Ngày tải lên :
20/02/2014, 01:20
... T (2005)
Functional importance of Ca
2+
-deficient N-terminal
lobe of molluscan troponin C in troponin regulation.
Arch Biochem Biophys 436, 83–90.
H. Tanaka et al. Functional regions of molluskan ... and the structural and functional
features of some invertebrate troponins. Molluskan
TnC binds only one mole of Ca
2+
per mole of protein
at site IV in the C-domain because of amino acid sub-
stitutions ... significance of the differ-
ence in TnI–TnC interactions, we compared the ability
of TnC to neutralize the inhibitory effects of the C-ter-
minal fragments in the presence and absence of Ca
2+
.
As...
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Tài liệu Báo cáo khoa học: Functional dissection of the Schizosaccharomyces pombe Holliday junction resolvase Ydc2: in vivo role in mitochondrial DNA maintenance pptx
Ngày tải lên :
20/02/2014, 11:20
... and the unpairing
of four base-pairs in the centre of the junctions [19]. Detailed
understanding of the functional role of these interactions
would require the crystal structure of the Ydc2–junction
complex.
In ... for
dominant-negative effects of truncated and point mutants.
The results of this experiment are shown in Fig. 7B.
Expression of wild-type Ydc2–GFP resulted in a clear
reduction of the mtDNA content of the cells. ... conformation
of the junction, then the deletion of this motif would have an
even more serious effect on Ydc2 binding in the presence of
divalent cations. We tested the effect of Mg
2+
on the
binding of...
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