from concept to clinic

... this paper, we will refer to the organization as RHSTEP 14 SOCIAL DETERMINANTS APPROACHES TO PUBLIC HEALTH: from concept to practice Devolution from the State to NGOs From the 1980s, NGOs in Bangladesh ... heidibartjohnston@gmail.com 10 SOCIAL DETERMINANTS APPROACHES TO PUBLIC HEALTH: from concept to practice Abstract Every year, globally, an estimated 66 500 women die attempting to terminate a pregnancy To ... sector providers such as kabiraj live in rural areas in closer proximity to most women than a clinic, purdah is likely to be a strong motivator to women accessing care in the informal sector...

Ngày tải lên: 07/03/2014, 04:20

... receptors are weak prognostic indicators and should not be used to determine whether to treat a patient with adjuvant therapy Newer guidelines from a Oncogene and Cancer – From Bench to Clinic ... receptors and maintaining the receptor in an auto-inhibited form Binding of its native ligand to the receptor brings domains I and III close together, switching the receptor’s conformation to the ... guidelines) is to monitor response to therapy in the metastatic breast cancer setting Candidate Protein Biomarkers with possible clinical application in breast cancer i Topo2-alpha (Topo2) DNA topoisomerase...

Ngày tải lên: 16/03/2014, 21:20

... the cytoskeleton Many of these regulatory actions related to cell morphol‐ ogy are achieved through rapid, non-classical signaling of sex steroid receptors to kinase cascades, independently from ... produce estradiol from androgens Testosterone contributes to the production of estradiol, while the estrogen estrone is made from androstenedione Phytoes‐ trogens have analogous effects to those of ... P4 13 14 Steroids - From Physiology to Clinical Medicine production, in structural regression to forma corpus albicans and into a follicular develop‐ ment and entrance into a new follicular phase...

Ngày tải lên: 16/03/2014, 21:20

... development FGF from the myotome induces epithelial to mesenchymal transition and translocation of dermomytomal cells into the central region of the myotome [57], a process known to contribute to the ... M, Uramoto I, Totsuka T (2000) Differential adaptation of growth and differentiation factor 8/myostatin, fibroblast growth factor and leukemia 22 Skeletal Muscle – From Myogenesis to Clinical ... receptor, either activin receptor-like kinase (ALK4 or ActRIB) or ALK5 to stimulate the phosphorylation of receptor Smad and the Smad2/3 transcription factors in the cytoplasm This leads to the...

Ngày tải lên: 16/03/2014, 21:20

... improve the process The auto industry took 50 years to absorb the lessons of Lean, until customer and investor patience wore out In mid-2009, on the day General Motors emerged from bankruptcy, CEO ... lesson of the past decade is that we need supportive tooling, too.28 To prevent the practice from diverging from common sense, the tools need to reinforce the flow of value, reduce the waste, and ... or exploratory testing, not by test automation www.it-ebooks.info An Example When a tester files a bug, VS 2010 automatically invokes up to six mechanisms to eliminate the guesswork from fault...

Ngày tải lên: 22/03/2014, 20:21

... own demands and offers its own rewards to the operator This book shows the logical progression from dream to reality, from concept to finding a market gap to operating a restaurant Along the way, ... Contents Chapter Concept, Location, and Design 62 Restaurant Concepts 63 Defining the Concept and Market 68 Successful Restaurant Concepts 70 Concept Adaptation 77 Changing or Modifying a Concept 77 ... understood why people go to restaurants to be together and to connect with one another It is very important that the restaurant reinforce why guests choose it in the first place Restaurants exist to...

Ngày tải lên: 23/03/2014, 08:20

... receptors are weak prognostic indicators and should not be used to determine whether to treat a patient with adjuvant therapy Newer guidelines from a Oncogene and Cancer – From Bench to Clinic ... receptors and maintaining the receptor in an auto-inhibited form Binding of its native ligand to the receptor brings domains I and III close together, switching the receptor’s conformation to the ... guidelines) is to monitor response to therapy in the metastatic breast cancer setting Candidate Protein Biomarkers with possible clinical application in breast cancer i Topo2-alpha (Topo2) DNA topoisomerase...

Ngày tải lên: 23/03/2014, 14:20

... receptors are weak prognostic indicators and should not be used to determine whether to treat a patient with adjuvant therapy Newer guidelines from a Oncogene and Cancer – From Bench to Clinic ... receptors and maintaining the receptor in an auto-inhibited form Binding of its native ligand to the receptor brings domains I and III close together, switching the receptor’s conformation to the ... guidelines) is to monitor response to therapy in the metastatic breast cancer setting Candidate Protein Biomarkers with possible clinical application in breast cancer i Topo2-alpha (Topo2) DNA topoisomerase...

Ngày tải lên: 31/03/2014, 19:20

... contributions from all those participating in this field; clinicians, scientists, and engineers from academia, industry and the regulatory community Author details Department of Transfusion Medicine, Clinical ... and tissue regeneration Cytotherapy 2009, 11:377-391 doi:10.1186/1479-5876-8-31 Cite this article as: Stroncek and Puri: Cell and gene therapies: moving from research to clinic Journal of Translational ... deficiencies Hematology Am Soc Hematol Educ Program 2009, 682-689 Herrmann JL, Abarbanell AM, Weil BR, Wang Y, Wang M, Tan J, Meldrum DR: Cell-based therapy for ischemic heart disease: a clinical update...

Ngày tải lên: 18/06/2014, 16:20

... when he gets the chance, to travel to Corsica, to the village of Aquadilici where his family is from Maria Pia Fanti received the laureate degree in electronic engineering from the University of ... critical differentiators 60 cross-functional system 163 cross-organizational collaboration 362 CSM-process 370 customer-service management 369 customer -to- business (C2B) 93 customer relationship ... papers He is managing editor of IEEE Transactions on Systems, Man and Cybernetics, associate editor of IEEE Transactions on Automation Science and Engineering, and editor in chief of International...

Ngày tải lên: 21/06/2014, 13:20

... the stock, and outflow that decreases the stock To determine the flow rate, it is required to have system thinking about the target with a full dependency graph Causal links from one variable to ... deployed into a run-time environment for execution Monitoring phase: The running process is monitored continuously Various key performance indicators (KPIs) are synthesized and reflected to the ... representation, we chose BPEL to be our target implementation language During the monitoring phase, the running system has to be continuously monitored and the low-level IT metrics have to be synthesized...

Ngày tải lên: 21/06/2014, 13:20

... workforce to connect to the EIS for information relevant to their task Security is the main concern and therefore EIS agents act as guards and filters to allow only the authorized users to connect to ... costs to program into the agent the operation and even the management knowledge elicited are minimized Also, expertise to handle practical problems can be incorporated into the options function to ... functions are to carry out quality consultations and customer services, with commitments in improving customer relationships (thereby increasing sales) Users employ MWM systems to assist their...

Ngày tải lên: 21/06/2014, 13:20

... cooperate to provide the required service (according to the service-definition milestone) The description of the milestones suggests a top-down design trajectory, starting from service definition to ... relationship to PIM are not yet well understood, we refrain from discussing milestones that could be related to CIMs in this chapter The platform-independent service-design milestone corresponds to a ... quality, and return on investment—stem from the possibility to derive different implementations (via different PSMs) from the same PIM, and to automate to some extent the model-transformation...

Ngày tải lên: 21/06/2014, 13:20

... the history match or validate against the templates in the formal semantics of the schemes Definition 26: Well-Formed Local History A local history is said to be well formed if it conforms to the ... tell us that it is possible to decide whether a local history conforms to the formal semantics of one of the schemes In addition, if a local history does not conform to the formal semantics of ... away from the office, interacting with clients and collecting data Sometimes mobile devices not have enough space to store the data, while at other times employees need to access real-time data from...

Ngày tải lên: 21/06/2014, 13:20

... capability for original files to be constructed from less available blocks For example, k original blocks can be reconstructed from l (l is close to k) coded blocks taken from a set of ek (e is a ... 2002a) Compared to UDDI, the ebXML repositories are intended for more general-purpose storage UDDI is more specialized and geared toward the type of information that can be stored in the white, ... different terms, supplier or contractor, for the same concept If both companies map their concepts to an object whose identifier is CC 0815, they may talk to each other without ambiguity Such...

Ngày tải lên: 21/06/2014, 13:20

... the chapter In order for WS-Net to monitor and verify real-life applications, the translation from WSDL into WS-Net must be automated Meanwhile, since all transient tokens are created by local transitions ... output places via connectors In order to handle complexity, transition substitution is used to fold and unfold hierarchical services composition into modularized nets according to the architectural ... transportation cost, etc.) This decision level has to select the actors of the stages and the transportation and information links that have to connect the actors To this aim, an integer multicriteria linear...

Ngày tải lên: 21/06/2014, 13:20

... processes, from product design and procurement to marketing and customer-service management, in order to be more responsive to customer needs The new trend of mergers and acquisitions will continue to ... Management Customer-Service Management Benefits • SC Visibility (Information Sharing) Capturing feedback from the customers, providing a mix of products and service offerings customized to customer needs ... service to resist change while maintaining function and to recover to normal levels of function after a disturbance To meet these requirements, Web services have to assess their environment prior to...

Ngày tải lên: 21/06/2014, 13:20

... development FGF from the myotome induces epithelial to mesenchymal transition and translocation of dermomytomal cells into the central region of the myotome [57], a process known to contribute to the ... receptor, either activin receptor-like kinase (ALK4 or ActRIB) or ALK5 to stimulate the phosphorylation of receptor Smad and the Smad2/3 transcription factors in the cytoplasm This leads to the ... M, Uramoto I, Totsuka T (2000) Differential adaptation of growth and differentiation factor 8/myostatin, fibroblast growth factor and leukemia 22 Skeletal Muscle – From Myogenesis to Clinical...

Ngày tải lên: 29/06/2014, 09:20