folding unfolding of short peptides using statistical models

... think of our approach as the “control of nonlinear systems using piecewise affine models , which is a special case of “control of nonlinear systems using multiple models 1.3 Identification of nonlinear ... Identification of Switched Linear Systems using Multiple Models 119 5.5.3 5.6 Design of One-Step-Ahead Controllers for Switched Linear System 117 Identification of Switched Nonlinear Systems using Multiple ... Identification of nonlinear system via PWARX models 56 3.6 Identification of the nonlinear system via PWARX model using Classifier I 58 3.7 Identification of the nonlinear system via PWARX model using...

Ngày tải lên: 10/09/2015, 15:50

... consequence of the presence of the same kind of spectrum for 4N complexes of GGH, where the a carbon of the His residue is the sole source of chirality [10] However, while positions of the component ... studies of the Ni(II) complex of HSA [6] Due to different protonation patterns, the stability constants of particular complexes of model peptides cannot be compared directly There are two ways of ... in DMF was used for capping of unreacted peptides chains Cleavage was effected using a mixture of triuoroacetic acid, H2O, and TIS (v/v/v ẳ 95/2.5/2.5) over a period of 2.5 h, followed by precipitation...

Ngày tải lên: 22/02/2014, 04:20

... | B ) Figure 6: Results of F1-measure comparing the segmentation results using different statistical models of lexical chain features We further compare the performance of various scoring methods ... the probability of seeing a lexical chain start / end at a particular instance is independent of the starts / ends of other chains As a result, the probability of seeing a sequence of chain starts ... as an indicator of the structure of text”, Computational Linguistics, 17(1), pp 21–48 Reynar, J.C 1999, Statistical models for topic segmentation”, Proc 37th annual meeting of the ACL, pp 357–364...

Ngày tải lên: 23/03/2014, 17:20

... 1999) 33 Many models were explored regarding dielectric properties of soft tissue in its frequency domain since the 1940s Most of the models explored relate the dielectric property of soft tissue ... networks of resistor and capacitor Kunii et al (1998) made used of a lumped element circuit model with an increasing branch of resistor and capacitor in series in modeling of soft tissue of different ... structure A definition of multi-scale model is a model which includes components from two or more of these levels of organization (multiple length scales) One of the main aims of multi-scale model...

Ngày tải lên: 08/09/2015, 18:21

... characterization of the unfolding of insulin and proinsulin using the reductive unfolding method has not been thoroughly investigated We have characterized the unfolding process of an artificial ... study the reductive unfolding of HPI in the absence of denaturant, we used the disulfide scrambling method to monitor the HPI unfolding process Fig Unfolding of HPI in the presence of denaturant and ... role of C-peptide in the folding/ unfolding of HPI (Eur J Biochem 271) 1739 difference between PIP and HPI in the refolding pathway However, our studies of the oxidized refolding process of PIP...

Ngày tải lên: 19/02/2014, 12:20

... and covers 80% of their lists (our system does not find some of the lowprobability range verbs of Lapata and Lascarides) We compared the rankings of the two implementations in terms of Pearson correlation ... see(7)) was stored This means that sense of watch, sense of view and sense of see would be correct interpretations of the metonymic expression The obtained number of synsets ranges from 14 (try shampoo) ... defaults in the form of the qualia structure of the noun The qualia structure of a noun specifies the following aspects of its meaning: The obtained results demonstrate the effectiveness of our approach...

Ngày tải lên: 20/02/2014, 09:20

... extremely sensitive for the detection of unfolding ⁄ refolding intermediates of proteins [24–26] Figure shows the phase diagrams representing the unfolding of Phe16Trp FBPase, Phe89Trp FBPase, ... assay used for the examination of protein unfolding, trypsin (20 lg proteinÆmL)1) was added to the assay mixture [13] Equilibrium unfolding Equilibrium unfolding of FBPases was performed in 0.1 ... sensitive approach for the detection of unfolding ⁄ refolding intermediates of proteins [25,27,35] The essence of this method is to build up the diagram of I(k1) versus I(k2), where I(k1) and...

Ngày tải lên: 07/03/2014, 05:20

... generation-space models Natural Language Engineering, 14(4):431–455, 2008 J Bilmes and K Kirchhoff Factored language models and generalized parallel backoff In Proceedings of HLTNAACL, short papers, ... are represented as factored language models smoothed using Witten-Bell interpolated backoff smoothing (Bilmes and Kirchhoff, 2003), according to the backoff graphs in Fig Variables which are ... systems is the lack of availability of domain-specific data It is therefore essential to produce NLG models that minimise the data annotation cost BAGEL supports the optimisation of the data collection...

Ngày tải lên: 17/03/2014, 00:20

... process of molecular recognition and self-assembly must occur to enable the formation of such well-ordered, supramolecular structures Short peptides as models for amyloid formation As a result of ... chemistry and biochemistry One key example of the association of peptides into large ordered deposits is the spontaneous self-assembly of short aromatic peptides into ordered polymeric b-sheet tapes ... Model peptides to study amyloid fibril formation Inhibition by short peptides Analyzing short peptide fragments is crucial for developing small peptide inhibitors of this amyloidogenic process Using...

Ngày tải lên: 23/03/2014, 11:20

... ,Xn: areas of the forms of land use and the land use methods 1, 2, ,n; a1,a2, ,an: exporting coefficients of phosphorus 2) Point sources: the amount of P from sewage (P4) In the case of Bay Mau ... months Fig Dynamic of PB, PE, PiN in 12 months Table Decrease of Cpl, PS, and content of PS Decreases of Cpl (%) Decreases of PS (%) Content of PS (mg/l) 50 48.89 - 49.53 2.08 - 4.14 75 73.46 - 74.16 ... Calculating the amount of phosphorus loading to the lake 3.1.2.1 Using empirical watershed model To calculate, we applied technological standards of OECD and Loer [1] The main sources of phosphorus include:...

Ngày tải lên: 28/03/2014, 15:20

... what sorts of information are most important Further work will attempt to improve the accuracy of the predictor, using new knowledge sources We will explore the use of the concept of a confidence ... smoothing using the open-class tag distribution, instead of the overall distribution, will offer better results 3.2 3.3 C o n t e x t u a l I n f o r m a t i o n Contextual probabilities offer another ... measure, as well as using only infrequently occurring words from the lexicon to train the predictor, which would presumably offer a better approximation of the distribution of an unknown word...

Ngày tải lên: 31/03/2014, 04:20

... a greater understanding of the role of this process in the development of AD-type pathology Unfortunately, knowledge of the extent of complement activation in animal models is lacking This paper ... Complement activation in animal models of AD: present knowledge The examination of complement activation in experimental models of AD has been limited to mice and rats The extent of complement activation ... extent of complement activation and its association with neuropathology must be determined in animal models of AD to clarify the relevance of these models for investigating the significance of complement...

Ngày tải lên: 19/06/2014, 22:20

... normal distribution of mean 500 bases and standard deviation of 50 bases Polymorphisms were added to the simulated genome at a rate of 1/1000 with a 1/3 Page 11 of 12 probability of being a homozygous ... implementation of SRMA Author details Department of Computer Science, University of California - Los Angeles, Boelter Hall, Los Angeles, CA 90095, USA 2Department of Human Genetics, David Geffen School of ... error rate, thus limiting further utility of this type of comparison The variant calls of SRMA are improved genome-wide by SRMA, and several dramatic examples of sequence improvement can be demonstrated...

Ngày tải lên: 09/08/2014, 22:23

... structure of the bone and soft tissue Contours of the face are composed of a balance of hard and soft tissues The mandibular contour along the inferior border depends mainly on the shape of the ... 2005, in the Department of Maxillofacial Surgery of the University of Udine, an operative protocol was applied with the preoperative realization of stereolithographic models for all the patients ... rehearsal allows measurement of the displacement of all bone segments and anticipation of the size and the form of bone grafts; using these techniques requires the development of reference points so...

Ngày tải lên: 11/08/2014, 23:22

... number of observations, and the number of observations often exceeds 106 Thus, a method to estimate genetic heterogeneity of the residual variance in animal models with a large number of observations ... estimates of variance components using the PQL version of DHGLM Re-analyses of pig litter size: data and models Pig litter size has been previously analyzed by Sorensen & Waagepetersen [6] using ... shown) Hence, the GenStat version of DHGLM is suitable for Page of 10 sire models but not for animal models if the number of observations is large An advantage of GenStat, however, is that it produces...

Ngày tải lên: 14/08/2014, 13:21

... Z-SCORE OF ADJUSTED BASE PAIR DISTANCE Z-SCORE OF SECOND (OR THE FIEDLER) EIGENVALUE Z-SCORE OF ADJUSTED MINIMUM FREE ENERGY OF FOLDING Z-SCORE OF ADJUSTED BASE PAIRING PROPENSITY Z-SCORE OF ADJUSTED ... List of Figures xi List of Abbreviations xv List of Abbreviations xv List of Mathematical Symbols and Notations xvi Chapter Introduction 1.1 Background of MicroRNAs 1.2 Contributions of ... examiners Prof Peter Clote (Biology Department of Boston College), Prof Vladimir B Bajic (Deputy Director of South African National Biodiversity Institute), and Prof Peter Stadler (University of Leipzig),...

Ngày tải lên: 11/09/2015, 16:05

... COMPRESSION OF 4D MEDICAL IMAGE AND SPATIAL SEGMENTATION USING DEFORMABLE MODELS YAN PINGKUN (B.Eng (Electronic Engineering), USTC) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ... 6.14 Segmentation results of MRA image B using the CGAC method 113 6.15 MIP of the MRA image C 114 6.16 Segmentation results of the 3D MRA image C using our CGAC method ... 114 6.17 MIP of the MRA image D 115 6.18 Segmentation results of cerebral MRA data set D using the CGAC 116 xiii List of Tables 3.1 3.2 Lossless performance of different...

Ngày tải lên: 15/09/2015, 22:16

... In this tutorial, we show how to simulate circuits using ModelSim You need Quartus II CAD software and ModelSim software, or ModelSim-Altera software that comes with Quartus II, to work through ... display of design units in your circuit in a form of a table The columns of the table include the instance name, design unit and design unit type names The rows of the table take a form of an expandable ... through the circuit using logic and wiring delays of zero This simulation is fast and useful for checking the fundamental correctness of the designed circuit The second step of the simulation process...

Ngày tải lên: 04/05/2016, 00:03

... the Experimental Animals Laboratory of Dokuz Eylul University Faculty of Medicine The purpose of using rats is easy availability, safety, and the high ratio of repeating the experiment Design ... the Care and Use of Laboratory Animals Statistical analysis The results were recorded by the principal investigator and analyzed statistically upon completion of the study The statistical analysis ... intensities of adhesion among Groups A, B and C Number of rats Group A (n=4) Group B (n=8) Ethics The study was approved by a local ethics board of Dokuz Eylul University Faculty of Medicine,...

Ngày tải lên: 25/10/2012, 11:00

... effect of dark reaction (the effect of adsorption of TCE on the TiO2 powder), as well as the photolysis of TCE by solar radiation only in the absence of TiO2 Figure showed the degradation ratio of ... instead of simply transferring them to another medium (Ahmed et al., 1984; Glaze et al., 1993) The purpose of our study is to investigate the feasibility of the solar detoxification using TiO2 ... carried out by injecting a sampling of TCE into the slurry of TiO2 to given a final solution of 50 ppm TCE The run in the dark condition (TiO2 alone) showed about 20% of TCE degradation after hours,...

Ngày tải lên: 05/09/2013, 08:40