explain the disease and disorder of both the eye and ear

Báo cáo khoa học: On the thermodynamic equilibrium between (R)-2-hydroxyacyl-CoA and 2-enoyl-CoAOn the thermodynamic equilibrium between (R)-2-hydroxyacyl-CoA and 2-enoyl-CoA doc

Báo cáo khoa học: On the thermodynamic equilibrium between (R)-2-hydroxyacyl-CoA and 2-enoyl-CoAOn the thermodynamic equilibrium between (R)-2-hydroxyacyl-CoA and 2-enoyl-CoA doc

... and Discussion For the determination of the experimental value of K b , we performed activity measurements in both the for- ward and reverse directions, requiring the preparation of both 1b and ... from the measured equilibrium con- stant of 0.017 (0.1 kJặmol )1 ). The absolute magnitude of the free energies of solvation of 1b and 2b are much larger than those of 1c and 2c, because of the ... electron to the thioester carbonyl, forming a ketyl radical anion (3, Scheme 1). This allows the elimination of the a-hydroxyl group [3,4] (3 fi 4) and lowers the pK a of the b-hydrogen in the resulting...

Ngày tải lên: 29/03/2014, 08:20

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THE FOURTEENTH CENTURY.—DECLINE OF AGRICULTURE.—THE BLACK DEATH.— STATUTE OF LABOURERS potx

THE FOURTEENTH CENTURY.—DECLINE OF AGRICULTURE.—THE BLACK DEATH.— STATUTE OF LABOURERS potx

... number of the free labourers were swept away, and their labour lost to the lord of the manor; the services of the villeins were largely diminished from the same cause; many of the tenants, both ... change. The economic position of the villeins, the administration of the demesne, and the whole organization of the manor were revolutionized. Much of the tenants' land had reverted to the ... payments, [120] with the result that the manorial system began to break up rapidly. Owing to the dearth of labourers for hire, and the loss of many of the services of their villeins, the lords found...

Ngày tải lên: 29/06/2014, 15:20

10 181 0
fraud and responsibilities of auditor in detecting and preventing of fraud

fraud and responsibilities of auditor in detecting and preventing of fraud

... Objective of the research Before collecting of suitable information and data, the researcher must define clearly objectives of research to help readers understand the target of these researches. ... detecting and 19 CHAPTER 3 RESEARCH METHODOLOGY 3.1 Research problem 3.1.1 Aim of the research The aim of this research is to help the reader to understand about the fraud and then to ... questionnaire, the researcher will provide the title and brief explanation to help the respondents understand the topic easily. The questions were also designed based on some of the content of prior...

Ngày tải lên: 13/03/2014, 14:20

56 467 1
Báo cáo khoa học: "Evaluation of annual ring width and ring density development following fertilisation and thinning of Scots pine" pdf

Báo cáo khoa học: "Evaluation of annual ring width and ring density development following fertilisation and thinning of Scots pine" pdf

... effects of fertilisation and thinning on ring width and ring den- sity and (ii)to establish the relationring width –ring den- sity and test if there were additional effects of fertilisation and thinning ... removed 46% of the stems from the full range of diameter classes. Urea was applied by hand in the spring of 1984 before growth commenced. The ex- periment was laid out using a rectangular grid of adjacent 30 ... The stand was regenerated by both direct seeding and natural regeneration. Seed trees were felled in 1956, and the stand was pre-commercially thinned in 1972. At the start of the experiment in 1983,...

Ngày tải lên: 08/08/2014, 14:20

12 270 0
Báo cáo Y học: Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot

Báo cáo Y học: Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot

... used Sc-RNase H2* and Tk-RNase HII as model proteins to analyze the effect of a disease- causing mutation on the activity, stability, and structure of human RNase H2 and the role of the glycine residue ... comparable to the sum of the molecular masses of three subunits in a His-tagged form (89 336), and 53 kDa for the second peak, which is comparable to the sum of the molecular masses of Sc-Rnh2Bp* and Sc-Rnh2Cp* ... 0.01 a The k cat values of the mutant proteins relative to that of the parent protein. b The specific activities were determined at the substrate concentration of 1 l M. c The specific activities of the...

Ngày tải lên: 17/03/2014, 17:20

14 483 0
Báo cáo khoa học: Sulfated polysaccharides inhibit the catabolism and loss of both large and small proteoglycans in explant cultures of tendon doc

Báo cáo khoa học: Sulfated polysaccharides inhibit the catabolism and loss of both large and small proteoglycans in explant cultures of tendon doc

... the rate of [ 35 S]sulfate appear- ing in the medium was suppressed by the inclusion of the sulfated polysaccharides. At the end of the culture period, both CaPPS and heparin reduced the appear- ance ... inclusion of these sulfated agents there was significant inhibition (40%) of rate of loss of 35 S-labeled large proteogly- cans from the matrix by the end of the culture period. Similarly, by day 10 of ... macromolecules that appeared in the medium on each day of culture and that remaining in the matrix at the end of the culture period [41]. From these data, the per- centage of 35 S-labeled proteoglycans...

Ngày tải lên: 23/03/2014, 10:21

10 414 0
báo cáo hóa học:" Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report" docx

báo cáo hóa học:" Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report" docx

... the gathered reports for the described injury. NC composed and wrote the manuscript. Both authors read and approved the final manuscript. References 1. Peterson CA and Peterson HA: Analysis of ... was used in the majority of type I and II injuries and could have contributed to the poor outcomes in t his group. Conclusion Fractures of the proximal tibial epiphysis are rare, and the potential ... degrees of flexion) and open reduction and internal fixation of displaced type III, IV and V. Some authors regret not fixing type I and II fractures, with subsequent loss of reduction and unsatisfactory...

Ngày tải lên: 20/06/2014, 04:20

5 420 0
Báo cáo khoa học: "ACTH-producing carcinoma of the pituitary with refractory Cushing''''s Disease and hepatic metastases: a case report and review of the literature" pptx

Báo cáo khoa học: "ACTH-producing carcinoma of the pituitary with refractory Cushing''''s Disease and hepatic metastases: a case report and review of the literature" pptx

... contributions HC performed the bilateral adrenalectomy and together with SP and RS contributed to the conception and design of the manuscript, reanalyzed and interpreted the data and prepared the manuscript. ... contributed to the con- ception and design of the manuscript, reanalyzed and interpreted the data and helped in preparation of manu- script. RS. contributed to the conception and design of the manuscript, ... course of fractionated radiotherapy and the development of metastases varied from 15 months to 18 years. Indeed, while radiotherapy was locally effective in our patient – post-radiotherapy MRI of the...

Ngày tải lên: 09/08/2014, 04:21

7 407 0
Báo cáo khoa học: " Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death" docx

Báo cáo khoa học: " Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death" docx

... combined requirement for both mitochondria and the ER in the induction and the signaling pathways of ciPCD mediated by ceramide. Background The survival and homeostasis of multicellular organisms critically ... mechanisms of ciPCD are just beginning to be unraveled, e. g. by the recent identification of RIP3, enzymes of the energy metabolism, Nox1, CYLD, Bmf, and cathepsin and calpain proteases as candidate ... suppression of ciPCD in concert with its mitochondrial and ER-specific func- tions. In summary, the further exploration of the exact roles of mitochondrial, ER- and nucleus-specific Bcl-2 as well as their...

Ngày tải lên: 09/08/2014, 10:20

9 388 0
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis

The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis

... transformation of these tissues. The dual function of the Rb gene family in differentiation and cell cycle control explains the fre- quent involvement of loss of pocket protein function in a subset of human cancers. 10 Conclusion A ... studied. Numerous biochemical and genetic studies have elucidated in great detail the function of the Rb gene and placed it at the heart of the molecular machinery controlling the cell cycle. As more ... functions and interactions. The difference in phosphorylation sites and kinases involved in the phosophorylation of these sites between p107 and p130 further support specific functions for p107 and p130....

Ngày tải lên: 25/10/2013, 21:20

43 460 0

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