evaluation of the immune system

... the basis of classical theories of immune surveillance and more recent awareness of the tumour-promoting properties of innate immune cells, researchers are now investigating the efficacy of ... approaches is how therapeutically manipulating one arm of the immune system affects the anticancer or cancer-promoting properties of the other. For example, induction of anticancer humoral immune responses ... feature that sets them apart from adaptive immune cells. Acute activation of innate immunity sets the stage for activation of the more sophisticated adap- tive immune system. Induction of efficient...

Ngày tải lên: 15/03/2014, 01:20

... digesting the fragment with HindIII and Bgl II and the plasmid with HindIII and Bam HI. The fragment was ligated into the plasmid and the integrity of the insertion was validated by digesting the plasmid construct ... contributing to the phosphorylation of the wild-type siglec tail by Lck and Jak3 kinases. By comparison, the mutation of the tyrosine at position 641 did not significantly affect the degree of phosphorylation ... plate and determining the binding of the polyacrylamide biotinylated glycoconjugates (Fig. 5A). In the first panel, the 2,6 0 -PAA conjugate bound significantly greater than either the unsialylated...

Ngày tải lên: 24/03/2014, 04:21

... recognized for the regulation of immune responses. The effect of parasites, for example, has been to dampen, rather than fully ablate, immune responsiveness, and the degree of immunosuppression ... lend support to this hypothesis. The immune response to parasitic infection The first line of defense against parasites, as with other pathogens, is the innate immune system, which is ‘hard- wired’ ... recruiting the antigen-specific T and B cells of the adaptive immune system to proliferate and differentiate into effector cells competent to attack the infection. It is therefore the evasion of...

Ngày tải lên: 06/08/2014, 19:20

Ngày tải lên: 12/08/2014, 18:20

Ngày tải lên: 13/08/2014, 16:20

Ngày tải lên: 03/01/2014, 19:39

... con- trastive summary, the number of fragments of the reference summary which are also in the contrastive summary, in relation to the size of the contrastive summary. DocSim: The number of documents used ... QARLA, for the evaluation of text summarisation systems. The in- put of the framework is a set of man- ual (reference) summaries, a set of base- line (automatic) summaries and a set of similarity ... Combination) 6/9 Table 1: Results of the test of identifying the manual summariser 287 Figure 1: Illustration of some of the restrictions on Q, K is reliable, or the evaluation outcome may change by...

Ngày tải lên: 17/03/2014, 05:20

... heuristics. The probability of a resulting word is the product of the probabilities of the applied rules. The result is a list of target words sorted by their associated probabilities, L i . The first system ... consonants and vowels. The full de- tails of this system are not important for this paper; here we focus on the performance evaluation of sys- tems, not the systems themselves. 2.1 System Evaluation In ... inserted in the text to represent a source word, it is important that the word at the top of the system generated list of target words (by def- inition the most probable) is one of the words gen- erated...

Ngày tải lên: 23/03/2014, 18:20

... buffalo is similar to the composition in cattle. One of the unique features to emerge from the study of the immune system of cattle is the presence of two complex subpopulations of γδ T cells, one ... vaccines, it is necessary to characterize the immune system of the water buffalo and elucidate the changes in the immune response that account for the development of protective immunity. To achieve this ... existing sets of mAbs developed in other related species. With the mAbs identified here, it will now be possible to characterize the immune system of the water buffalo and begin to analyze the immune...

Ngày tải lên: 07/08/2014, 15:20

... in the development of autoimmune or allergic disease, respectively. To achieve this state of immune tolerance, the immune system has evolved a variety of mechanisms. These include deletion of ... induction of regulatory T cells. The review will address the induction of the three types of regulatory T cells, the mechanisms by which they suppress T-cell responses in the periphery, the role they ... periphery. Likewise, the immune system is continuously distinguishing between innocuous and pathogenic foreign antigens. To deal with these situations the immune system has evolved a system of induced...

Ngày tải lên: 09/08/2014, 01:24

... lesions. The new 7 th edition (TNM-7) of the AJCC/UICC TNM system [10], which was introduced in 2009, is a modified version of the 6 th edition (TNM-6) of this system. The major modifications of ... as the period from the date of hepatectomy to the date of recurrence as detected by imaging studies. Overall survival (OS) was defined as the period from the date of hepatectomy to the date of ... (Figure 1). These modifications bring new issues to ongoing debates over tumor staging. The purpose of the present study, therefore, was to assess the validity of the TNM-7 staging system for...

Ngày tải lên: 09/08/2014, 02:21

Ngày tải lên: 12/08/2014, 04:21

Ngày tải lên: 12/08/2014, 11:22

Ngày tải lên: 12/08/2014, 22:22

Ngày tải lên: 13/08/2014, 08:20

Ngày tải lên: 13/08/2014, 11:22

Ngày tải lên: 12/09/2012, 15:05