... the basis of classical theories of immune surveillance and more recent awareness of the tumour-promoting properties of innate immune cells, researchers are now investigating the efficacy of ... approaches is how therapeutically manipulating one arm oftheimmunesystem affects the anticancer or cancer-promoting properties ofthe other. For example, induction of anticancer humoral immune responses ... feature that sets them apart from adaptive immune cells.Acute activation of innate immunity sets the stage for activation ofthe more sophisticated adap-tive immune system. Induction of efficient...
... digesting the fragment with HindIII andBgl II and the plasmid with HindIII and Bam HI. The fragment was ligated into the plasmid and the integrity of the insertion was validated by digesting the plasmidconstruct ... contributing to the phosphorylation of the wild-type siglec tail by Lck and Jak3 kinases. Bycomparison, the mutation ofthe tyrosine at position 641 didnot significantly affect the degree of phosphorylation ... plate and determining the binding of the polyacrylamide biotinylated glycoconjugates (Fig. 5A). In the first panel, the 2,60-PAA conjugate bound significantlygreater than either the unsialylated...
... recognized for the regulation of immune responses. The effect of parasites, for example, has been to dampen, rather than fully ablate, immune responsiveness, and the degree of immunosuppression ... lend support to this hypothesis. The immune response to parasitic infection The first line of defense against parasites, as with other pathogens, is the innate immune system, which is ‘hard-wired’ ... recruiting the antigen-specific T and B cells ofthe adaptive immune system to proliferate and differentiate into effector cells competent to attack the infection. It is therefore the evasion of...
... con-trastive summary, the number of fragments of the reference summary which are also in the contrastive summary, in relation to the size of the contrastive summary.DocSim: The number of documents used ... QARLA, for the evaluation of text summarisation systems. The in-put ofthe framework is a set of man-ual (reference) summaries, a set of base-line (automatic) summaries and a set of similarity ... Combination) 6/9Table 1: Results ofthe test of identifying the manual summariser287 Figure 1: Illustration of some ofthe restrictions on Q, Kis reliable, or theevaluation outcome may changeby...
... heuristics. The probability of aresulting word is the product ofthe probabilities of the applied rules. The result is a list of target wordssorted by their associated probabilities, Li. The first system ... consonants and vowels. The full de-tails of this system are not important for this paper;here we focus on the performance evaluationof sys-tems, not the systems themselves.2.1 System Evaluation In ... inserted in the text to represent asource word, it is important that the word at the top of thesystem generated list of target words (by def-inition the most probable) is one ofthe words gen-erated...
... buffalo is similar to the compositionin cattle. One ofthe unique features to emerge from the study oftheimmunesystemof cattle is the presence of twocomplex subpopulations of γδ T cells, one ... vaccines, it is necessary tocharacterize theimmunesystemofthe water buffalo andelucidate the changes in theimmune response that accountfor the development of protective immunity. To achievethis ... existing sets of mAbs developed in other related species. With the mAbsidentified here, it will now be possible to characterize the immunesystemofthe water buffalo and begin to analyze the immune...
... in the development of autoimmune or allergic disease,respectively. To achieve this state ofimmune tolerance, the immunesystem has evolved a variety of mechanisms.These include deletion of ... induction of regulatory T cells. The review willaddress the induction ofthe three types of regulatory T cells, the mechanisms by which theysuppress T-cell responses in the periphery, the role they ... periphery. Likewise, theimmunesystem iscontinuously distinguishing between innocuous andpathogenic foreign antigens.To deal with these situations theimmunesystem hasevolved a systemof induced...
... lesions. The new 7th edition (TNM-7) ofthe AJCC/UICC TNM system [10], which was introduced in 2009, is a modified version ofthe 6th edition (TNM-6) of this system. The major modifications of ... as the period from the date of hepatectomy to the date of recurrence as detected by imaging studies. Overall survival (OS) was defined as the period from the date of hepatectomy to the date of ... (Figure 1). These modifications bring new issues to ongoing debates over tumor staging. The purpose ofthe present study, therefore, was to assess the validity ofthe TNM-7 staging system for...
... idea of the high prevalence of edema in the more advanced grades of cellulite. The lack of specific clinical and laboratory studies hinders research on cyclic edema and the dissemination of ... associated with the more advanced stages. The control of edema is essential in the treatment of cellulite. Conflict of Interest The authors have declared that no conflict of in-terest exists. ... this disease. The fact that it is idiopathic is another limiting factor to its management as there are few reports about treatment in the literature. During theevaluationof patients with...
... should concern: the audience, the aims, the content, and the methodology.13 3. Significance ofthe thesis The findings ofthe thesis will be useful not only to the researcher, and the course book ... with the hope that practical suggestions would be given for further improvements ofthe material in the near future to meet the target of ensuring the effectiveness ofthe teaching and the learning ... development.3.1.2. The Suitability ofthe Material to the Content Requirements ofthe Course 3.1.2.1. Syllabus analysis To determine whether the material has well responded to the content requirements of the...
... (%)Chart 2: Learners’ evaluation on the usefulness ofthe topics ofthe ESP reading texts in the coursesAs shown in chart 2, no one thinks that the topics ofthe ESP reading texts in the courses 1, ... texts, the length ofthe ESP reading texts, the amount of technical vocabulary contained in each ESP reading text, the level of difficulty in grammar, the usefulness of exercises, the most ... necessity of replacing the reading texts in the textbook by the ESP reading texts To answer the survey question of whether the reading texts in the textbook should be replaced by the ESP readings...