ensure that the display variable is set correctly on the remote computer
Báo cáo khoa học: Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is a-D-Gal-(1fi3)-a-D-GalNAc pot
Ngày tải lên :
23/03/2014, 13:20
... revealed that the glycan configuration is not the same as that previously discovered and reported for contulakin-G (Conus geographus) This surprising result establishes that the O-glycosylation of ... are consistent with the theoretical peptide mass (2252.6 Da) Disulfide bond formation In preparation for the Cys2-8 disulfide reaction, each component was injected on analytical HPLC under isocratic ... concentrations, but we did not further determine the configuration of this carbohydrate However, the different elution profiles of the native tx5a and the synthetic peptides constructed with the...
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Báo cáo sinh học: " A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis" pptx
Ngày tải lên :
18/06/2014, 22:20
... particles Virion morphogenesis appears to arrest at a stage prior to core condensation The observation that there is still some processing of p4b in the absence of TET and yet the morphology of the mutant ... condensation and allows progression to the formation of intracellular mature virus If the activity of the I7L proteinase is blocked, viral morphogenesis arrests prior to core condensation If the ... regulate the expression of the I7L gene from the infecting recombinant virus This conditional-lethal expression system has recently been used to show that the enzymatic activity of the VV G1L...
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Báo cáo hóa học: " Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a " pptx
Ngày tải lên :
20/06/2014, 01:20
... even in the presence of NHEJ [8,27], http://www.virologyj.com/content/5/1/11 whereas others reported efficient transduction even in the absence of ATM [28,29] One explanation is that these discrepancies ... reduced HIV-1 transduction If this were the case, then the NBS1 deficiency should not affect HIV-1 transduction in the absence of vpr To test this hypothesis, we infected control and NBS1-deficient ... of these two proteins In this context, we note that some HIV-1 transduction occurs even in the absence of normal NBS1 or ATM (see Results section) It is possible that this residual transduction...
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báo cáo hóa học:" A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis" potx
Ngày tải lên :
20/06/2014, 04:20
... particles Virion morphogenesis appears to arrest at a stage prior to core condensation The observation that there is still some processing of p4b in the absence of TET and yet the morphology of the mutant ... condensation and allows progression to the formation of intracellular mature virus If the activity of the I7L proteinase is blocked, viral morphogenesis arrests prior to core condensation If the ... regulate the expression of the I7L gene from the infecting recombinant virus This conditional-lethal expression system has recently been used to show that the enzymatic activity of the VV G1L...
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Báo cáo y học: "Etanercept versus etanercept plus methotrexate: a registrybased study suggesting that the combination is clinically more efficacious" pptx
Ngày tải lên :
09/08/2014, 01:23
... revealed statistically significantly better results for the combination therapy as compared with the monotherapy after months The other Available online http://arthritis-research.com/content/5/6/R347 ... response and for remission Discussion We analysed the clinical responses to treatment with etanercept either as monotherapy or when added to baseline therapy with MTX The present results show that ... maximal, making an additional effect of MTX much harder to detect It is important to underscore that the comparison in this study is between, on the one hand, etanercept monotherapy initiated in...
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Báo cáo khoa học: " Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene)" pot
Ngày tải lên :
12/08/2014, 04:20
... establish that feasible structures exist that are consistent with the secondary structure predictions and with the assignment of BDV G as a class III VFP Discussion Proteomics computational analyses ... determinations The three VFP classes for enveloped virus membrane glycoproteins were established based on structural similarities in the post-fusion configurations Therefore, it is likely that there is ... highly variable The virion configuration of VSV G is homotrimer arranged in a tripod shape with the fusion domains corresponding to the legs of the tripod [31] No structural prediction of the prefusion...
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Báo cáo y học: " Indications that "codon boundaries" are physico-chemically defined and that protein-folding information is contained in the redundant exon bases" pot
Ngày tải lên :
13/08/2014, 23:20
... codons in the intronic sequences, therefore we continued the same phase that we applied to the exon, assuming that this kind of selection is correct, and maintained the denotation of the phase ... through the interactions of complementary segments The novel observation here is that these interactions preferentially involve the 1st and 3rd codon residues This connection between the RNA secondary ... work rather well but not perfectly and some scientists remain unconvinced that codon asymmetry explains the exon-intron differences satisfactorily Another codon-related problem is that the well-known,...
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Topic : It is likely that the Technological advances will replace language teachers soon. Do you agree or disagree?
Ngày tải lên :
30/05/2015, 20:49
... role in the future of education But not as big role as that of a teacher Works Cited Cheng-Chieh Lai, William Allan Kritsonis (2006) The Advantages and Disadvantages of Computer NATIONATIONAL JOURNAL ... involves the technology which support to studying language For example, in order to take part in an online English course , they have at least a smatphone, an ipad, a computer or an cassette that connect ... student’s problems with pronunciation, syntax, or usage by the tacher In other words, technologies are not yet intelligent enough to be truly interactive “Due to the limitations of computer s artificial...
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Khơi thông những nút thắt thể chế để phục hồi tăng trưởng
Ngày tải lên :
14/02/2014, 08:45
... http://doji.vn/he-thong-tap-doan/cong-ty-lien-ket-gop-von/ngan-hang-tmcp-tien-phong/ Xem http://thebusiness.vn/Home/Article/2036/Do-Minh-Phu -Ong-chu-Doji-va-ong-chu-moi-cua-Tienphong-Bank Khơi thông ... tiến mới.20 Trong bối cảnh môi trường kinh doanh không cải 18 http://doanhnhan.vneconomy.vn/20101130015756103P0C5/cuoc-chien-voi-giay-phep-con-cat-xong-lai-moc.htm http://www.thesaigontimes.vn/Home/doanhnghiep/quantri/85664/ ... (VELP) tháng năm 2012 26 OECD (2007), Economic Importance of Agriculture for Sustainable Development and Poverty Reduction: The Case Study of Vietnam, Paris 27 Theo Tổng cục Thống kê Việt Nam, tỷ...
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Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
Ngày tải lên :
18/02/2014, 08:20
... required for the insertion of ISP into the bc1 sub-complex, but the presence of only one of these two subunits does not substitute for the other After the addition of ISP, the binding of the last ... would be that the addition of the ISP to the 500 kDa sub-complex induces the bc1 dimerization In this context, it is worth noting that ISP exists as transdimer structure, as clearly demonstrated ... and that the binding of ISP and Qcr10p is subsequent to that of Bcs1p Previous studies have suggested that the insertion of ISP into the bc1 complex would replace the bound Bcs1p on the basis...
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Tài liệu Protest Fee Schedule for Thunder Cars: Protestor must verify with the INEX inspector that the proper tools are available to check protested items ppt
Ngày tải lên :
19/02/2014, 04:20
... with the latch on the A-Pillar and hinges on the B-Pillar rather than the traditional method of the latch on the B-Pillar and the hinges on the A-Pillar Suicide doors are only permitted on the ... points are the front of the rear tire sidewall and the front and rear of the front tire sidewall The measurement is then taken from the front edge of the front wheel to the front edge of the rear ... rail on the front clip along the contour of the fender, and may only be trimmed in 3” from the edge The inside of the fenders near the grille, the edge of the fenders near the body shell, and the...
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Báo cáo khoa học: Heterologous synthesis of cytochrome c¢ by Escherichia coli is not dependent on the System I cytochrome c biogenesis machinery ppt
Ngày tải lên :
06/03/2014, 00:20
... The arrow and arrowhead indicate the positions of the PHCP and PH c552 proteins, respectively The band denoted by the asterisk on the right-hand side is the result of nonspecific staining of the ... Biogenesis of cytochrome c¢ Heterologous synthesis of PHCP by E coli The E coli System I cytochrome c biogenesis machinery, consisting of the Dsb and Ccm proteins, is responsible for the synthesis ... comparison, which will provide information on the function of Ccm proteins Structural implication for PHCP synthesis Although the sequence identity is low between the PHCP protein and the EC...
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Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot
Ngày tải lên :
08/03/2014, 16:20
... convulxin This is consistent with the observation that TPO, which is unable to induce activation of PKC, does not stimulate activation of ERK in platelets This result indicates that activation ... suggest that activation of RAS is dispensable for efficient activation of ERK DISCUSSION Activation of RAS was evaluated in platelets through the ability of the activated RAS–GTP to bind a GST fusion ... in other cell types is also mediated through the SRC kinases [17–19] PP1 also inhibited activation of RAS stimulated by convulxin, consistent with the role of these kinases in mediation of the...
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ELA, Promissory Notes and All That: The Fiscal Costs of Anglo Irish Bank pdf
Ngày tải lên :
22/03/2014, 17:20
... of the ECB Governing Council. Despite the impression that this is a complex issue requiring technical discussions, the key question is whether the members of the ECB Governing Council are willing to lower the burden on the Irish people due their government’s decision to take over the liabilities of ... 6 The ABCs of ELA This section discusses the process by which Exceptional Liquidity Assistance is issued and moves on to the various legal and accounting issue related to the issuance and repayment of ELA. ... at ensuring an adequate flow of information within the Eurosystem to the decision‐making bodies of the ECB. In this way, the impact of an ELA intervention on aggregate liquidity conditions in the euro area can be managed in a manner consistent with the maintenance of the appropriate single ...
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Federal Banking Regulators Could Better Ensure That Consumers Have Required Disclosure Documents Prior to Opening Checking or Savings Accounts ppt
Ngày tải lên :
22/03/2014, 21:20
... institutions to disclose (among other things) the amount of any fee that may be imposed in connection with an account and the conditions under which such fees are imposed.2 Regulation E the other ... institutions to combine the disclosure information required by the regulation with that required by other laws such as TISA as long as the information is clear and understandable and is available ... by institutions that advertise them In general, examinations are risk-based that is, targeted to address factors that pose risks to the institution—and to help focus their examinations of individual...
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Báo cáo khoa học: Chinese hamster apurinic⁄apyrimidinic endonuclease (chAPE1) expressed in sf9 cells reveals that its endonuclease activity is regulated by phosphorylation docx
Ngày tải lên :
23/03/2014, 03:20
... Although the results of their reports were somewhat conflicting, the consensus conclusion was that phosphorylation regulates the two important functions of human APE1 [38–40], which might switch on ... 30 lL of reaction under the standard condition, and the subsequent procedures of the assay were the same as described above The Michaelis–Menten analysis was carried out with the SigmaPlot enzyme ... volume The standard curve was constructed with solutions of known concentration of phosphorus and sulfur and other elements for references, in parts per billion concentration The absolute concentration...
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Báo cáo khoa học: Characterization of the interactions of the nephrin intracellular domain Evidence that the scaffolding protein IQGAP1 associates with nephrin potx
Ngày tải lên :
23/03/2014, 13:20
... orifice of lm The needle voltage was optimized in the range 900–1700 V, with the cone voltage set at 40 V For the acquisition of collision-induced dissociation (CID) spectra, the collision energy ... in the recovery after disruption of the filtration barrier [32,33] One possibility is that the nephrin–IQGAP1 interaction plays a role mainly during the formation of the slit diaphragm and the ... clear whether the nephrin– IQGAP1 interaction is a biologically relevant one, study of the IQGAP1 literature strongly supports the notion that this could be the case Rac1 and Cdc42 belong to the Rho...
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Báo cáo khoa học: UMP kinase from the Gram-positive bacterium Bacillus subtilis is strongly dependent on GTP for optimal activity potx
Ngày tải lên :
31/03/2014, 07:20
... question arises: can the concentration of GTP and UTP play a role in the metabolism of B subtilis in vivo? From the total concentration of different NTPs and Mg2+ in B subtilis, [47,48], it is conceivable ... experimental validation will be necessary to verify these hypotheses The present model gathers the sequence stretches that are well conserved among UMP kinases on one face of each monomer These faces ... coli under nonpermissive conditions, such as cold-sensitive growth or hypersensitivity to SDS [36] On the other hand, Trp58 of the B subtilis enzyme is conserved in Streptococcus pneumoniae, Strep...
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Báo cáo hóa học: " Bioinformatic analysis suggests that the Orbivirus VP6 cistron encodes an overlapping gene" potx
Ngày tải lên :
20/06/2014, 01:20
... indicating that ORFX is subject to stronger functional constraints than the overlapping section of VP6 In (7)–(8) the null model, in each window, is that only the VP6 frame is coding, while the alternative ... details of the MLOGD software The null model comprises the VP6 CDS and the query CDS is ORFX In each plot, the top panel displays the raw log(LR) statistics at each alignment position There is a separate ... 3, giving the ORFX AUG codon a strong Kozak context [18] • As far as amino acid constraints in the VP6 reading frame are concerned, there is no reason for the ORFX AUG codon to be conserved In...
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