endocannabinoid overactivity and abdominal obesity

 Báo cáo y học: " Carotid Intima-media thickness in childhood and adolescent obesity relations to abdominal obesity, high triglyceride level and insulin resistance"

Báo cáo y học: " Carotid Intima-media thickness in childhood and adolescent obesity relations to abdominal obesity, high triglyceride level and insulin resistance"

Ngày tải lên : 25/10/2012, 11:40
... IMT was closely associated with obesity especially abdominal obesity in childhood and adolescence as confirmed by our correlation analysis and regression analysis Obesity has been demonstrated ... atherosclerosis begins in obese children and adolescents, and this tendency is intensified in the presence of MetS Obesity especially abdominal obesity, high TG level and insulin resistance are strong ... exceptional patient care and organization This work was supported, in part, by grant of Zhejiang Science and Technology Agency (2008C03002-1) and Zhejiang Major Medical and Health Science and Technology...
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Waist circumference, abdominal obesity, and depression among overweight and obese U.S. adults: national health and nutrition examination survey 2005-2006" doc

Waist circumference, abdominal obesity, and depression among overweight and obese U.S. adults: national health and nutrition examination survey 2005-2006" doc

Ngày tải lên : 11/08/2014, 15:22
... and waist circumference or between sex and abdominal obesity were observed in fully adjusted models When data analyses were further stratified by BMI and abdominal obesity status, abdominal obesity ... (1.06-4.48) 2.03 (0.98-4.24) - abdominal obesity 52 1.49 (0.28-7.80) 1.31 (0.26-6.52) 1.19 (0.23-6.00) + abdominal obesity Obese - abdominal obesity + abdominal obesity 1,185 3.28 (1.91-5.65) ... BMI and abdominal obesity revealed that overweight adults with abdominal obesity were more likely to have depressive symptoms (by both definitions) than overweight adults without abdominal obesity; ...
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What is known about the effectiveness of economic instruments to reduce consumption of foods high in saturated fats and other energy-dense foods for preventing and treating obesity? docx

What is known about the effectiveness of economic instruments to reduce consumption of foods high in saturated fats and other energy-dense foods for preventing and treating obesity? docx

Ngày tải lên : 17/03/2014, 08:20
... respectively, were: -0.54 and -0.25 for rice, -0.54 and -0.35 for wheat flour, -0.09 and -0.03 for coarse grains, -0.96 and -0.33 for pork, -0.03 and -0.40 for eggs, and -0.39 and -0.47 for edible ... participants were randomized into five groups including no treatment, standard behavioural treatment (SBT), SBT and food provision, SBT and incentives and SBT, food provision and incentives The ... Halpern MT Cost of obesity in the workplace Scandinavian Journal of Work and Environmental Health, 2006, 32(1):5–11 Seidell JC Societal and personal costs of obesity Experimental and Clinical Endocrinology...
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Healthy Eating, Active Living: An action plan to improve diet, increase physical activity and tackle obesity (2008-2011) pdf

Healthy Eating, Active Living: An action plan to improve diet, increase physical activity and tackle obesity (2008-2011) pdf

Ngày tải lên : 22/03/2014, 13:20
... activity and obesity Obesity is a complex problem This was recently made clear in the Foresight Report which provided evidence that the causes and determinants of obesity are broad ranging and involve ... Trends and Habits in Scotland Trends in obesity among adults in Scotland The Scottish Health Survey indicates that for adults aged 16-64 years there has been a rising trend in overweight and obesity ... activity and tackle obesity (2008-2011) Greenspace Scotland Greenspace Scotland30 is supported by the Scottish Government to promote the goal of everyone living and working in urban Scotland having...
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báo cáo hóa học: " Comparing the SF-12 and SF-36 health status questionnaires in patients with and without obesity" pot

báo cáo hóa học: " Comparing the SF-12 and SF-36 health status questionnaires in patients with and without obesity" pot

Ngày tải lên : 18/06/2014, 22:20
... study, analyzed and interpreted the data and drafted the manuscript RD and MBH contributed to the design and interpretation of the analysis All authors read and critically revised and approved the ... correlation between PCS-12 and PCS-36 and between MCS-12 and MCS-36 for the entire sample and by BMI group The Pearson correlation was 0.82 for the physical component summary scores and 0.95 for the mental ... illness, and quality of life We calculated body mass index (BMI) from self-reported height and weight and categorized respondents as normal weight, overweight, and obese according to standard guidelines...
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ANEURYSMAL DISEASE OF THE THORACIC AND ABDOMINAL AORTA pptx

ANEURYSMAL DISEASE OF THE THORACIC AND ABDOMINAL AORTA pptx

Ngày tải lên : 27/06/2014, 17:20
... years with the advent and generalised use of abdominal ultrasonography there has been an accurate, cheap and non invasive tool for the diagnosis of abdominal aortic aneurysms Abdominal ultrasonography ... Netherlands and centres in Belgium This study focused on short term combined mortality and morbidity outcomes45 It The Evidence for Management of Abdominal Aortic Aneurysms: Lessons Learned from Randomised ... Sukhija R, Aronow WS, Sandhu R, Kakar P, Babu S Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins Am...
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Báo cáo y học: "Diagnostic implications of soluble triggering receptor expressed on myeloid cells-1 in patients with acute respiratory distress syndrome and abdominal diseases: a preliminary observational study" potx

Báo cáo y học: "Diagnostic implications of soluble triggering receptor expressed on myeloid cells-1 in patients with acute respiratory distress syndrome and abdominal diseases: a preliminary observational study" potx

Ngày tải lên : 14/08/2014, 07:21
... A-sTREM and P-sTREM to diagnose lung and abdominal infections, respectively Nine patients had lung infection (without abdominal infection), had abdominal infection (without lung infection), and had ... of our inability to obtain abdominal fluid The mean age (± standard deviation) was 48.2 ± 16.7 years, and 57% (n = 12) were males Eleven patients (52%) had a chronic abdominal disease, seven patients ... higher CPIS and a greater alveolar sTREM-1 (P = 0.019 and P = 0.019, respectively) compared with those without lung infection The patients with abdominal infection had a lower CPIS and increased...
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Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant  6

Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant 6

Ngày tải lên : 17/09/2015, 17:19
... could modulate UCP1 activity and lipid metabolism and contribute to the development of obesity and diabetes As Cidea expression is highly restricted to brown adipocytes and its deletion results in ... regulating energy expenditure and the development of obesity and diabetes The illustration of Cidea’s association with BAT UCP1 and its involvement in fatty acid β-oxidation and lipid metabolism, which ... status and perspectives in obesity research Obesity Reviews 1, 61-72 Gordon, J W., and Ruddle, F H (1982) Germ line transmission in transgenic mice Prog Clin Biol Res 85 Pt B, 111-124 Green, D., and...
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Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant  5

Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant 5

Ngày tải lên : 17/09/2015, 17:19
... fact it has been shown in several classic obesity models and knock-out mouse models that development of hyperglycemia and obesity depends on gender and 97 Chapter strain background (Naggert et ... obtained from embryonic day 15, day 18 and postnatal 1-week mice Sections A, B and C were probed with an anti-sense Cidea RNA probe and sections D, E, and F were probed with an anti-sense UCP1 ... screen and bands were quantified by a Bio-rad FX Imager RNA levels were normalized against that of βactin and presented as fold difference for mice at different ages (B) or cold exposed, fasted and...
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Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant  4

Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant 4

Ngày tải lên : 17/09/2015, 17:20
... transgenic and knockout models are very powerful tools for gene function research The first publications of such techniques appeared in 1980 (transgenic) and 1991 (knockout) respectively (Gordon and ... 1991) The introduction of the mouse embryonic stem cells in the late 1980s (Evans and Kaufman, 1981) and the creation and successful use of vectors for homologous recombination in the early 1990s ... cells can be propagated and cultured on a layer of feeder fibroblast cells and growth media containing leukemia inhibitory factor (LIF), which prevents differentiation and thus ensuring the maintenance...
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Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant  3

Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant 3

Ngày tải lên : 17/09/2015, 17:20
... mM MgCl2, and mixed with 250 µM each of deoxy-adenine, deoxy-cytosine, deoxy-guanine and deoxy-thymidine nucleotides (New England Biolabs), 50 pM of the sense and anti-sense primers, and 2.5 Units ... 2.3.2.5 Secondary and tertiary screening of genomic DNA library The films were developed and aligned with the original plates, and the agar under each individual spot was cut out and placed in 1ml ... for h and injected intraperitoneally with saline or isoproterenol (10 mg per kg body weight) Blood was collected from the orbital plexus before (0 min) and 15 after injection and serum NEFAC and...
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Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant 2

Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant 2

Ngày tải lên : 17/09/2015, 17:20
... hypertension, stroke and diabetes and clinical conditions such as hyperlipidermia (reviewed by Lowell and Spiegelman, 2000; Pi-Sunyer, 2003; Spiegelman and Flier, 2001) Obesity develops only ... been unequivocally demonstrated DFF40 and DFF45 mRNAs and proteins are expressed in most tissues and cell lines Cell lines expressing high levels of DFF40 and DFF45 quickly undergo DNA fragmentation ... with Cidea and FSP27, is responsible for Cideb induced cell death, mitochondrial localization and dimerization (Chen et al., 2000) Unlike the ubiquitous DFF45 and DFF40, both Cidea and Cideb are...
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Physiological roles of CIDEs  CIDEA deficient mice exhibit lean phenotype and are obesity resistant

Physiological roles of CIDEs CIDEA deficient mice exhibit lean phenotype and are obesity resistant

Ngày tải lên : 17/09/2015, 17:20
... both Cidea and Cideb Also thanks Esther Wong and all the other staffs of in vivo unit for providing excellent technical support and working environment for animal model generation and animal ... information on obesity and adipose tissue 11 1.5.1 Obesity 11 1.5.2 Body weight regulation 12 1.5.3 The liver plays a central role in lipid transport and metabolism ... Rationale and aim of research 30 iv Table of Contents Chapter Materials and Methods 31 2.1 Chemicals and reagents 32 2.1.1 General list of cell culture medium and reagents...
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Báo cáo y học: "Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level" doc

Báo cáo y học: "Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level" doc

Ngày tải lên : 09/08/2014, 22:23
... contributions OH and VB performed the sequencing and statistical analysis GB and VB performed the rare variant analysis MS and JS performed the mass spectrometry experiments OH, XW and MN designed and performed ... between obesity and EC system genes Thus, FAAH and MGLL are excellent candidates to be sequenced in the extreme of the BMI distribution to find the extent of their genetic diversity and potential ... with obesity Results and discussion Selection of samples at extremes of the BMI distribution To increase the power of our study to detect variants associated with extreme obesity in the FAAH and...
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 Báo cáo y học: "Low socio-economic status, smoking, mental stress and obesity predict obstructive symptoms in women, but only smoking also predicts subsequent experience of poor health"

Báo cáo y học: "Low socio-economic status, smoking, mental stress and obesity predict obstructive symptoms in women, but only smoking also predicts subsequent experience of poor health"

Ngày tải lên : 31/10/2012, 15:34
... important role in the aetiology of asthma and that these hormones are influenced by obesity Direct effects of regurgitation due to abdominal obesity and inflammatory effects on the bronchioles ... linear regression model including VC, FEV1 and PEF and individual heights The other “standard” confounding factors for lung function measurements, gender and age, were not controlled for as the ... 1.2-8.9 and OR 4.6, 95% CI 1.6-13.3) and in relation to smoking status A significant trend was obstructive symptoms in 2000-2001 (OR 3.7, 95% CI found between smoking status and lower lung 1.8-8.0 and...
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Tài liệu The Practical Guide: Identification, Evaluation, and Treatment of Overweight and Obesity in Adults pdf

Tài liệu The Practical Guide: Identification, Evaluation, and Treatment of Overweight and Obesity in Adults pdf

Ngày tải lên : 14/02/2014, 09:20
... Aerobics Research; and Dr Van S Hubbard, National Institute of Diabetes and Digestive and Kidney Diseases The Practical Guide Identification, Evaluation, and Treatment of Overweight and Obesity in Adults ... Overweight and Obesity .5 Treatment Guidelines Assessment and Classification of Overweight and Obesity Assessment of Risk Status 11 Evaluation and Treatment ... Study of Obesity (NAASO) and the National Heart, Lung, and Blood Institute (NHLBI) It is based on the Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity...
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Tài liệu "Promoting healthy diets and physical activity: a European dimension for the prevention of overweight, obesity and chronic diseases" doc

Tài liệu "Promoting healthy diets and physical activity: a European dimension for the prevention of overweight, obesity and chronic diseases" doc

Ngày tải lên : 14/02/2014, 13:20
... Portugal and Italy report overweight and obesity levels exceeding 30% among children aged 7-11 The rates of the increase in childhood overweight and obesity vary, with England and Poland showing ... schools and the media Council conclusions on obesity, op cit Council conclusions on obesity, op cit Opinion of the European Economic and Social Committee on Obesity in Europe – role and responsibilities ... Building overweight and obesity prevention and treatment into health services Health services and health professionals have a strong potential for improving patients’ understanding of the relations...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

Ngày tải lên : 14/02/2014, 22:20
... Because glucose is the primary fuel for the CNS and blood glucose and hypothalamic malonyl-CoA levels fall and rise together during food deprivation and refeeding, it was reasoned that glucose metabolism ... integrate carbohydrate and lipid nutrient sensing in the brain and is an example of an enzyme that can sense and respond to the nutritional environment The major challenge to understanding the role ... in feeding behavior and energy expenditure For example, the hypothalamus can sense and respond to fluctuations in the levels of blood glucose [13], fatty acids [12,14,15] and certain amino acids...
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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Ngày tải lên : 14/02/2014, 22:20
... inflammation of adipose tissue in obesity and related insulin resistance [15] Here, we focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss whether these ... ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases The expression of ANGPTL2 and ANGPTL6 ⁄ AGF is induced in obese conditions ANGPTL2 induces chronic adipose tissue inflammation and ... serum levels and amelioration of diet-induced obesity and insulin resistance [14] Taken together, these findings suggest that ANGPTL6 ⁄ AGF in the circulation counteracts obesity and related insulin...
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Tài liệu Báo cáo khoa học: RMI1 deficiency in mice protects from diet and genetic-induced obesity pptx

Tài liệu Báo cáo khoa học: RMI1 deficiency in mice protects from diet and genetic-induced obesity pptx

Ngày tải lên : 16/02/2014, 09:20
... this mutant strain as described below) Body and organ weights as well as plasma parameters (Tables S2 and S3) were measured, and learning, memory and behavioral tests (Table S4) as well as histopathological ... ⁄ + and RMI1+ ⁄ ) mice in the oral glucose tolerance test (Fig 2E,F) Resistance to KK- and KK-Ay-induced genetic induced obesity in RMI1+/) mice To explore resistance to the development of obesity ... which exhibits both hyperphagia and severe features of type diabetes Both the KK and KK-Ay strains are useful for studying therapies for the prevention of diabetes and obesity We thus crossed RMI1+...
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