... structures, (iv) elevation of H2O2, and O2•-, (v) uncoupling of State and inhibition of State respiration, (vi) inhibition of OXPHOS Complexes II + III, IV and V activities and sometimes (vii) inducing ... proteome map of mouse liver mitochondria 81 Figure 17.Tandem mass spectrum of enoyl-CoA hydratase generated from MALDITOF/TOF MS/MS 82 Figure 18 Comparison of SOD1, SOD2, and GPX1 ... with the DNA-binding domains of PPARγ and RXRα and shields the highly polar side chains of the interacting residues (Asn 160 from PPARγ, and Arg 209 and Gln 206 of RXRα) from an aqueous environment...
Ngày tải lên: 12/09/2015, 11:08
... window, a bar chart is displayed of the significances of each of the choice and non-choice attributes The chart illustrates that PRICE, BRAND1, BRAND2, and BRAND4 are significant You can view other ... loss of information The rank of Y is the full number of columns in A and B In the example, q = When the rows of A and B are plotted in a two-dimensional scatter plot, the scalar product of the ... The juices and carbonated soft drinks are clustered at the left Grape and Apple juice are above the carbonated and sweet soft drinks and are perceived as more healthy than the other soft drinks...
Ngày tải lên: 18/02/2014, 07:20
Báo cáo khoa học: Systems biology: experimental design Clemens Kreutz and Jens Timmer docx
... parameters px and py An experimental design D species the choice of the external perturbations u, the choice of the observables g and the number and time points ti of measurements The way of stimulation ... clear denitions of the investigated hypotheses and the scope of the study are crucial Also, an overview of numerical optimization of designs for the purpose of parameter estimation and for model ... unraveled after averaging of repeated observations The spread of the distributions after averaging is quantied by the standard error rli of the estimated mean ^ p ^ li of condition i, which is...
Ngày tải lên: 23/03/2014, 06:20
Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships pot
... of factor terms to parameterize biases can lead to underfitting of some bias sources and overfitting of others While it seems natural to model intensity-dependent relationships as functions of ... intensities of each comparison group (the straight line in the right panel of Figure 1) and treat deviations from this mean as bias The distinction between the original and warped versions of the ... major contribution is the formulation of the two-channel microarray experiment in terms of the fANOVA model and the consideration of estimation in the absence of its functional arguments reports...
Ngày tải lên: 29/03/2014, 14:20
Báo cáo hóa học: " Research Article Design and Experimental Evaluation of a Vehicular Network Based on NEMO and MANET" pdf
... supports both NEMO and MANET connectivity In this paper, the focus is on investigating the operation and performance of the simultaneous usage of VANET and NEMO routes An initial set up of a field testbed ... set of indoor and oudoor experiments have been conducted also at the Rocquencourt campus of INRIA and this section presents and analyzes most interesting results 6.1 Experimental Setup Details and ... maintaining MR1 (and thus MNN1) moving in a 65 meters radius around the position of MR2, and reporting the achievable throughputs None of the MRs have gone out of the access points’ coverage and a building...
Ngày tải lên: 21/06/2014, 08:20
Báo cáo y học: "Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships" pptx
... of factor terms to parameterize biases can lead to underfitting of some bias sources and overfitting of others While it seems natural to model intensity-dependent relationships as functions of ... intensities of each comparison group (the straight line in the right panel of Figure 1) and treat deviations from this mean as bias The distinction between the original and warped versions of the ... major contribution is the formulation of the two-channel microarray experiment in terms of the fANOVA model and the consideration of estimation in the absence of its functional arguments reports...
Ngày tải lên: 14/08/2014, 20:22
Computer aided drug design of neuraminidase inhibitors and MCL 1 specific drugs
... Comparsion Of Zn33 And Oseltamivr Pose In N1_Closed And N9_Closed 89 Figure5.9 Comparsion Of Zn35 And Oseltamivr Pose In N1_Closed And N9_Closed 89 Figure5.10 Comparsion Of Zn21 And Oseltamivr ... algorithms, the handling of ligand and protein flexibility, and scoring functions (Lyne, 2002) Some of them are mentioned in Table1.1 CHAPTER 1: INTRODUCTION 15 Table1.1 Brief overview of some of the ... Of Oseltamivir And Zanamivir Poses In N1_Closed And N1_N294s 85 Figure5.4 Comparison Of Pose Of Oseltamivir, Zanamivir In N1_Closed And N1_H274y 86 Figure5.5 Comparison Of Poses Of Oseltamivir,...
Ngày tải lên: 09/09/2015, 11:06
Design, analysis, and experimental verification of continuous media retrieval and caching strategies for network based multimedia services
... referred to the storage space and the bandwidth capacity in servers The bandwidth capacity is determined by the minimum of the I/O bandwidth and the network bandwidth The I/O bandwidth is generally determined ... estimates of the bit rate and disk access times, and are used when users cannot tolerate any losses Statistical admission control algorithms use estimated probability distributions of the bit rate and ... lifetime of a document and the type of a document are also important factors that be considered in the design of replacement algorithms Perfect LFU and in-cache LFU are two variants of LFU Perfect...
Ngày tải lên: 17/09/2015, 17:17
Knowledge discovery in biomedical research and drug design the development and application of biological databases
... academic and company scientists And because of the efforts of these scientists and funding agencies such as NIH in USA and EMBL in Europe, Bioinformatics became more and more prominent and diverse ... of biological data has catalyzed the construction of databases for the data storage and distribution It has also stimulated the development of respective data CHAPTER 13 analysis tools and software ... Thousands of candidate compounds are screened, and only a limited number and success of compounds reach pre-clinical development for their activity, efficacy, selectivity, bioactivity, and pharmacokinetics...
Ngày tải lên: 17/09/2015, 17:19
Design, analysis and experimental verification of tubular spaceframe chassis for FSAE application
... longitudinal and vertical acceleration experienced by the race car at the center of gravity (CG) during skid pad event 292 2) Acceleration and Brake Test Graph 75-Longitudinal, associated lateral and ... unsprung mass of the race car during acceleration and brake test 293 Graph 76-Longitudinal, associated lateral and vertical acceleration experienced by the front right unsprung mass of the race ... acceleration and brake test 294 Graph 77-Longitudinal, associated lateral and vertical acceleration experienced by the rear left unsprung mass of the race car during acceleration and brake test...
Ngày tải lên: 12/10/2015, 17:36
Design, analysis and experimental verification of tubular spaceframe chassis for FSAE application 1
... 111-Investigation of auxiliary requirement of chassis Figure 112-Investigation of rule requirement (B.4.1) of chassis 2) Chassis Weight of Chassis vs Length of Foot Well 24.40 Weight of Chassis (kg) ... 550 600 650 700 Length of Foot Well (mm) Graph 44-Weight of chassis with respect to variation of length of foot well 213 STS of Chassis vs Length of Foot Well 537.00 TS of Chassis (Nm/deg) 536.80 ... Height of FBH (mm) Graph 47-Structural torsional stiffness (STS) of chassis with respect to variation of height of front bulkhead 4) Chassis Weight of Chassis vs Width of FBH 23.70 Weight of Chassis...
Ngày tải lên: 12/10/2015, 17:36
SAP2000® Linear and Nonlinear Static and Dynamic Analysis and Design of Three-Dimensional Structures
... and all associated documentation are proprietary and copyrighted products Worldwide rights of ownership rest with Computers and Structures, Inc Unlicensed use of the program or reproduction of ... trademark of Microsoft Corporation Adobe and Acrobat are registered trademarks of Adobe Systems Incorporated DISCLAIMER CONSIDERABLE TIME, EFFORT AND EXPENSE HAVE GONE INTO THE DEVELOPMENT AND DOCUMENTATION ... bridge spans 60 feet, and has a width and height of 12 feet each The supports are rollers at one end, and pins at the other The trusses and cross members are to be constructed of 2L4X4’s, while the...
Ngày tải lên: 06/09/2012, 15:56
SAP2000 Integrated Finite Elements Analysis and Design of Structures
... and all associated documentation are proprietary and copyrighted products Worldwide rights of ownership rest with Computers and Structures, Inc Unlicensed use of the program or reproduction of ... trademark of Microsoft Corporation DISCLAIMER CONSIDERABLE TIME, EFFORT AND EXPENSE HAVE GONE INTO THE DEVELOPMENT AND DOCUMENTATION OF SAP2000 THE PROGRAM HAS BEEN THOROUGHLY TESTED AND USED ... title of the window reads YZ Plane @ X=24 This same title also occurs on the left-hand side of the status bar at the bottom of the SAP2000 window Click the roof level beam on the left side of the...
Ngày tải lên: 06/09/2012, 15:56
Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... serological profiles fall outside of classical patterns Some key advantages and disadvantages of HBV DNA testing are presented in Table Current HBV DNA assays make use of differing technologies and can ... beacons) that decrease the number of handling steps, reduce contamination, and increase throughput and the accuracy of quantification will further enhance the utility of these assays [2,5] Given the ... is the appearance of serum markers of HBV infection that establishes the diagnosis of the disease Of these, HBsAg is considered to be the sentinel marker for the confirmation of acute infection...
Ngày tải lên: 03/11/2012, 09:41
An experimental investigation of heat transfer and fluid flow in a rectangular duct with inclined discrete ribs
... performance of solar air heater They reported that the geometry of the rib namely shapes, height, angle of attack and pitch affects significantly the heat transfer and friction characteristics of the ... inclined rib with relative gap position of 0.25 and relative roughness pitch of 8.0, with an angle of attack of 60º and with relative roughness height of 0.037 performers better then the other ... sheet arrangement for PIV measurement of single rib Results and discussion The results of experimental investigation of heat transfer and flow characteristics of the roughened ducts are presented...
Ngày tải lên: 05/09/2013, 16:10
An experimental investigation of performance and exhaust emission of a diesel engine fuelled with Jatropha biodiesel and its blends
... reason of higher BSFC of JOME and its blend was due to lower calorific value and the higher densities of JOME and blends caused higher mass injection for the same volume Figure Variation of BSFC ... waste land area suitable for Jatropha cultivation, it can supply large volume of biodiesel, in fact, nearly half a dozen states of India have reserve a total of 1.72 million hectares of land for ... and coatings It shows increased dilution and polymerization of engine sump oil, thus requiring more frequent oil changes For all the above reasons, it is generally accepted that blends of standard...
Ngày tải lên: 05/09/2013, 16:11
Theory and design of CNC systems (Học CNC)
... composed of two parts with a total of 11 chapters: Part I is composed of Chapters 1–6 on the principle and design of CNC, and Part II is composed of an open-architectural soft CNC system Specifically, ... invented the method of automatic control of the weaving of fabrics with a loom machine by using punch cards and this method was the beginning of the concept of NC The concept of NC was actually ... passing one slit of the rotation disk and one of the slits A, B, or Z on a fixed slit panel Slits A and B are arranged for a phase difference of 90 degrees and the electric signal of the output is...
Ngày tải lên: 08/09/2013, 20:50
An Introduction to Intelligent and Autonomous Control-Chapter 4:Design of Structure-Based Hierarchies for Distributed Intelligent Control
Ngày tải lên: 17/10/2013, 19:15
Theory and Design of Electrical and Electronic Circuits
... resistance of the copper of the wire of the secondary resistance of losses for Foucault and hysteresis distributed capacitance of the winding of the primary distributed capacitance of the winding of ... voltage of PINCH-OFF or "strangulation of the channel" defined in the curves of exit of the transistor, whose module agrees numerically with the voltage of cut in the curves of input of the transistor ... Transformadores of great value Equivalent circuit of a transformer Equivalent circuit of a inductor Measurement of the characteristics Transformer of alimentation Design Transformer of audiofrecuency...
Ngày tải lên: 23/10/2013, 16:15
Electronics - Theory and Design of Electrical and Electronic Circuits
... resistance of the copper of the wire of the secondary resistance of losses for Foucault and hysteresis distributed capacitance of the winding of the primary distributed capacitance of the winding of ... voltage of PINCH-OFF or "strangulation of the channel" defined in the curves of exit of the transistor, whose module agrees numerically with the voltage of cut in the curves of input of the transistor ... Transformadores of great value Equivalent circuit of a transformer Equivalent circuit of a inductor Measurement of the characteristics Transformer of alimentation Design Transformer of audiofrecuency...
Ngày tải lên: 27/10/2013, 16:15