different mechanisms of injury in different kinds of incidents
A study into the different mechanisms of anti cancer effect of docosahexanoic acid in colon cancer cells
... INTO THE DIFFERENT MECHANISMS OF ANTICANCER EFFECT OF DOCOSAHEXANOIC ACID IN COLON CANCER CELLS MANAV (B MED, GSMU, INDIA) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF SCIENCE DEPARTMENT OF COMMUNITY, ... RESULTS 3.2.1 Cytotoxic effects of PUFAs 3.2.1.1 Effect of different fatty acids on cell viability of HT-29 cells The effect of different fatty acids on the survival of human colon cancer cell line ... nomenclature of fatty acid molecules, PUFAs are classified into different groups on the basis of the position of the first double bond from the methyl terminus of the hydrocarbon chain of the molecule...
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Báo cáo khoa học: Two L-amino acid oxidase isoenzymes from Russell’s viper (Daboia russelli russelli) venom with different mechanisms of inhibition by substrate analogs pdf
... features of the dissociated cofactor were similar to those of FAD The shifting of absorption maxima of the enzyme-bound avin was due to its microenvironment The RP-HPLC proles of the cofactor ... level of glycosylation and homogeneity of the glycosydic part, as has been reported in the case of Ca rhodostoma LAAO [23], might be the cause of the chromatofocusing features for both the isoforms ... that the presence of 0.1% SDS did not affect the spectrum of FAD Identication of cofactor The absorption spectra between 300 and 600 nm of holo-LAAO from the active fractions of Sephadex G100...
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The Many Different Kinds of Debt ppsx
... million of debentures will be paid off and ($500 million - $320 million) = $180 million will be remitted to the parent In Subsidiary B, the $180 million of senior debentures will be paid off and ... increase the ratio of debt to tangible assets, it would decrease the value of unsecured debt because unsecured debt is junior to secured debt in the event of default 12 The issue of additional junior ... issuance of additional senior debt means that the same amount of equity supports a greater amount of debt; i.e., the firm’s leverage has increased, and the firm faces a greater probability of default...
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Studies on the mechanisms of the beneficial effects of herba leonuri and leonurine on traumatic brain injury in rat
... Pathophysiology of TBI Primary and Secondary Injury After TBI, the damage of brain tissue can be caused by primary and secondary injury mechanisms The primary injury refers to the direct effects of mechanical ... force of the fluid pressure pulse can be adjusted to achieve different levels of injury severity The central (CFP) and lateral (LFP) fluid percussion injury models produce a mixed type of brain injury ... I am grateful to Professor Wong Tsun Hon, Peter (Head of the Department of Pharmacology), as well as Associate Professor Tan Kwong Huat, Benny (Acting head of the Department of Pharmacology) for...
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Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
... transfection of Bag-1 Morpho/AS to JAR cells did not alter the expression of PTEN after the exposure to hypoxia, which would mean that the expression of PTEN, and also that of Bcl-X, was independent of ... expression profiles of proteins involved in the mitochondrial (bcl-2, bax, and bcl-x, etc.) and stress reaction-related pathways of apoptosis (Fig 2) Table Altered protein expression of JAR cells ... calculated according to the formula: Changes in the level of phosphorylated JNK 1&2 (-fold of control) = absorbance of treated cells / absorbance of control cells All points were done duplicate X three...
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Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... of action of some FP methods We did not state the mechanism of action of any FP methods and thus asked women to express their beliefs independently of their actual choices and independently of ... hypothetical method of FP In further sections women were asked about their knowledge of the mechanism of action of specific FP methods and if doctors or providers should explain the details of how a method ... minimized The implementation of the questionnaires was carried out in a short period of time in order to avoid the spread of information about the study among patients of the different health centres...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... of the active species [76] Further support in favour of the idea of the involvement of a high-valent iron-oxene in P450 catalysis came from experiments with metalloporphyrin models [5,6,77] Of ... of the crystal structure of NDO as well as spectroscopic data provide a rationale for the catalytic mechanism of this class of enzymes Naphthalene 1,2dioxygenase is a heterohexamer composed of ... reect ring opening of an epoxide intermediate at either of its two C-O bonds [219,220] The sum of these ndings strongly invokes the notion of oxygen activation during redox cycling of the diverse...
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Báo cáo khoa học: Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death ppt
... amounts of nitric oxide (NO) generated by pathological expression of NO synthase isoforms are certainly neurotoxic, whereas homeostatic levels of NO produced by the endothelial isoform of this ... suppression of excitation [67,71], persistent suppression of evoked inhibitory postsynaptic currents [72] and inhibitory long-term depression [73] All of these CB1-mediated mechanisms, often driven ... concentrations of either glutamate or GABA, depending on the brain area Hence, the differential inhibition of glutamate or GABA in various experimental models of cerebral ischemia may be one of the principal...
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Báo cáo khoa học: Mechanisms of accumulation of arachidonate in phosphatidylinositol in yellowtail A comparative study of acylation systems of phospholipids in rat and the fish species Seriola quinqueradiata pot
... is composed mainly of 1-stearoyl-2-arachidonoyl species also applies to tissues of yellowtail Accumulation of arachidonic acid in PtdIns in the presence of the large amounts of docosahexaenoic ... concentration of 50 lM, the level of acylation of docosahexaenoic acid to lysoPtdIns was 19.4 nmol per 10 per mg protein, which was about one-fifth of that obtained with the same concentration of arachidonic ... to clarify the involvement of the PtdIns cycle in the accumulation of arachidonic acid in PtdIns of fish Fig Effects of docosahexaenoic acid (DHA) on the incorporation of [14C]arachidonic acid (*AA)...
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Báo cáo khoa học: Modeling hydration mechanisms of enzymes in nonpolar and polar organic solvents potx
... aspect of this work is the analysis of the localization of water at the enzyme surface We have successfully identified regions of high density of water in close contact with the protein for the different ... we increase the polarity of the organic Modeling hydration mechanisms of enzymes solvent, as seen experimentaly [38] The dependence of enzyme structural properties on different water contents ... role in the solvation mechanism of the enzyme In this context, it would be important for a molecular interpretation of the effects of the different quantities of enzyme-bound water in nonpolar...
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Biochemical mechanisms of detoxification in higher plants
... circulation of contaminants in the ecosphere [277] 1.2 Migration of contaminants into different ecological systems 33 Migration of contaminants is first of all the tendency of compounds of different ... fond of highlighting This book has been written to provide an overview of the fundamental aspects of phytoremediation, to summarize existing understanding of the mechanisms of detoxification of ... [287] The main point of any technological process is an application of different types of action such as physical (e.g., mechanical), chemical, biological, or combinations thereof Often, after exhausting...
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Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart docx
... reperfusion injury ´ G de J Garcıa-Rivas et al Table Effect of different concentrations of the oxygen-bridged dinuclear ruthenium amine complex (Ru360) on the contractile force development of control ... fraction (2.3 ± 0.6 pmol of 103Ru360Æmg)1 of protein vs 1.2 ± 0.15 pmol 103Ru360Æmg)1 of protein; n ¼ 4) The purity of these fractions was determined by measuring the activities of d-glucose phosphate ... that accounted for 50% of the maximal uptake (14.3 ± vs 28.6 ± nmol of Ca2+ per mg of protein per min) RR induced 14% increase over control uptake (18.3 ± nmol of Ca2+ per mg of protein per min),...
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Báo cáo khoa học: A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells potx
... in various kinds of cancer cell lines and in clinical samples of ovarian carcinomas The characterization and functions of prosemin are described Results cDNA cloning and structure of the prosemin ... novel serine protease in various cancer cells A B C Fig Secretion of prosemin protein and expression of prosemin mRNA in various kinds of cancer cells (A) Conditioned medium (25 lg) from various cancer ... RTPCR was used to confirm the expression of prosemin mRNA in some cell lines A band of the predicted size (500 bp) of the PCR product was observed for most of the cell lines tested, including HPC-YO...
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MECHANISMS OF AESTHETIC EXAPTATION IN ARTEFACT DESIGN: HOW A BEAUX-ARTS GARDEN EVOLVED INTO AN AVANT-GARDE ART PARK pptx
... structure of human cognitive processes provided a solid microfoundation for the mechanisms of gradual evolutionary change (e.g Darwinian incremental differentiation by specialization of sub-systems) ... identify different areas of the park as envisioned by the architects and planners of the park Indeed, the architects of the project envisioned the design of Millennium Park as composed of separated ... perspective different from the one envisioned at the moment of the generation of the combination This process is qualitatively different from the pure integration or re-combination of elements...
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Báo cáo khoa học: Mechanisms of obesity and related pathologies: Role of apolipoprotein E in the development of obesity potx
... with time in differentiation, 5722 whereas the inhibition of lipid accumulation in differentiated cells by biotin deprivation decreased ApoE expression Interestingly, another set of experiments ... adipocyte differentiation [39], one interpretation of the results obtained by Huang et al [41] is that intrinsic defense mechanisms in adipose tissue limit adipogenesis by reducing the expression of ... depots present in mice expressing different ApoE isoforms Of course, obesity and its related complications are chronic dysfunctions that develop over long periods of time It is possible that weeks...
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Báo cáo khoa học: On the mechanisms of glycolytic oscillations in yeast potx
... is the abundance of AMP and ADP, and scarcity of ATP (i.e the minimum of the ATP oscillation instead of the maximum), and the inhibitory mode is abundance of FBP and scarcity of G6P and F6P Biochemically, ... rate of change of stability, which is a scaled measure of the change of the square of the amplitude, is given by: dRekị Rekị ẳ r0p : ẳ 4ị Cp d p=p In these equations, Re(k) is the real part of ... Westerhoff and coworkers have applied metabolic control analysis (a form of sensitivity analysis) on a number of mathematical models of glycolytic oscillations They conclude that the control of the...
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reaction mechanisms of inorganic and organometallic systems (topics in inorganic chemistry)
... type of modeling is capable of providing an indication of the effects of steric interactions on reactivity, but gives no measure of the actual energetics of the reaction More recently, modeling of ... slope of -k\ The linearity of such plots often is taken as evidence of a first-order rate law Since the assessment of linearity is somewhat subjective, it is better to show that the slope of such ... reaction rate and the rate of disappearance of reactants and rate of formation of products are related by In practice, it is not uncommon to define the rate only in terms of the species whose concentration...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008