deep brain stimulation as reversible destruction

... syndrome Br J Anaesth 2000, 85:129-135 Sakas DE, Kouyialis AT, Boviatsis EJ, Panourias IG, Stathis P, Tagaris G: Technical aspects and considerations of deep brain stimulation surgery for movement disorders ... system was a matter of debate, as there were no similar cases reported in the literature It was finally activated on the 20th postoperative day, after the patient had been extubated (stimulation ... Nonetheless, this case report supports the notion that stimulation may accelerate the patient’s recovery Consent Written informed consent was obtained from the patient for publication of this case report...

Ngày tải lên: 10/08/2014, 23:21

... BDI and HAMDS remained normal (Table 1) At all Case presentation A 58-year-old Caucasian man with a 13-year disease history of Parkinson’s disease was experiencing severe motor fluctuations His ... tests and interpreted these MS and AS finalized the manuscript References Benabid AL, Chabardes S, Seigneuret E: Deep- brain stimulation in Parkinson’s disease: long-term efficacy and safety - ... Albanese A, Volkmann J, Hariz MI et al.: Bilateral deep brain stimulation in Parkinson’s disease: a multicentre study with years follow-up Brain 2005, 128:2240-2249 Volkmann J, Allert N, Voges...

Ngày tải lên: 11/08/2014, 14:21

... impact of diseases resulting from our progressively ageing population [1] A prominent contributor to the future burden of disease will be cerebrovascular disease, or stroke, as well as neurodegenerative ... in some cases, and passive training resulted in no motor learning Can we augment recovery and plasticity with brain stimulation? One of the contemporary methods under investigation as a tool ... neuroplasticity is non-invasive brain stimulation The concept of treating neurological disorders with electricity is not new, and despite an interesting history dating back to ancient times, was...

Ngày tải lên: 19/06/2014, 08:20

... However, plasticity could also contribute to dysfunction such as spasticity after stroke or brain injury early in life (e.g cerebral palsy) Parkinson's disease Chronic progressive diseases are ... with Parkinson's disease: preliminary results Mov Disord 2007, 22:1046-1050 Fregni F, Simon DK, Wu A, Pascual-Leone A: Non-invasive brain stimulation for Parkinson's disease: a systematic review ... modulating synaptic plasticity Clin Neurophysiol 2006, 117:61-66 Been G, Ngo TT, Miller SM, Fitzgerald PB: The use of tDCS and CVS as methods of non-invasive brain stimulation Brain Res Rev 2007,...

Ngày tải lên: 19/06/2014, 08:20

... was increased or decreased by anodal or cathodal tDCS while subjects were learning a visually guided manual tracking task Accuracy of tracking movements was increased significantly by anodal stimulation, ... motor therapy, as well as the exact temporal window during which NIBS can be delivered in order to modulate brain plasticity and enhance the effects of the motor training How brain stimulation should ... human brain is related to the concept of homeostasis http://www.jneuroengrehab.com/content/6/1/8 – that is the human's brain ability to regulate changes in synaptic plasticity as to avoid drastic...

Ngày tải lên: 19/06/2014, 08:20

... doi:10.1186/1752-1947-4-74 Cite this article as: Moens et al.: Spinal cord stimulation as a treatment for refractory neuropathic pain in tethered cord syndrome: a case report Journal of Medical Case Reports 2010 4:74 ... spinal cord stimulator (SCS) was surgically placed when our patient was under epidural anesthesia An epidural catheter was inserted at levels L2 to L3 Our patient was injected with a loading dose ... offers a broader stimulation pattern, lower stimulation requirements, better long-term effectiveness, and lower migration rate Such are the technical advantages of plate electrodes as compared with...

Ngày tải lên: 11/08/2014, 11:23

... The midbrain connects the hindbrain and the forebrain, and is involved in auditory and visual responses as well as motor function Lastly, the hindbrain extends from the spinal cord and assists ... model was developed to determine whether scalp EEG technique was capable of measuring deep brain activities Finally the fourth study was to evaluate the performance of LORETA method applied in deep ... was to evaluate the reliability of using 3    the human head phantom system for EEG measurement before using the physical head model for subsequent deep brain activity measurement and deep brain...

Ngày tải lên: 09/09/2015, 10:02

... response measured by: à prolactin plasma levels à cortisol plasma levels Increase in prolactin and cortisol plasma levels following acute, single dose of citalopram (20 mg/kg, i.v.): CTL ¼ SP Brain ... measured by: à prolactin plasma levels à cortisol plasma levels Increase in prolactin plasma levels following acute challenge with fenfluramine: CTL ¼ SP Increase in cortisol plasma levels SP CTL DA ... and the Brain Defects 183 consequence of a malfunctioning in the brain is unlikely; it has not made social phobia more intelligible Knowing more, has not necessarily À as is often the case À resulted...

Ngày tải lên: 01/11/2013, 08:20

... subjected to permanent MCAO It was found that the p50 ⁄ p65 complex is activated in neurons during OGD as well as in ischemic brain areas of mice exposed to MCAO, whereas the c-Rel-containing dimers, ... channels is indispensable for basal NF-jB activity Three cellular sensors of Ca2+ levels – calmodulin, protein kinase C (PKC) and the p21(ras) ⁄ phosphatidylinositol 3-kinase (PI3K) ⁄ Akt pathway – ... [22] Stimulation of both the calmodulin kinase II and Akt kinase pathways are responsible for the upregulation of the p65 subunit of NF-jB [22] Activation of PI3K, mitogen-activated protein kinase...

Ngày tải lên: 07/03/2014, 03:20

... ischemic brain [35,38] It has also been proposed that post-ischemic PARP-1 activation contributes to increased expression of matrix metalloproteinases (MMPs), a group of zinccontaining proteases ... levels in plasma and brain [40], prevents brain matrix degradation, reduces delayed increase of BBB permeability and edema formation, preserves endothelial tight junction proteins and decreases delayed ... immune cells as well as infiltration of leukocytes within the ischemic area lead to excessive release of inflammatory mediators and ensuing worsening of brain damage In keeping with this, astrocytes,...

Ngày tải lên: 07/03/2014, 03:20

... (2) is read as: “classify f⋆ as idling class if P(I |f ) > P(D|f ), and vice versa.” The performance of the Bayesian classifier (2), expressed as classification accuracy, was then assessed by ... neurological injuries As the initial step towards achieving this goal, we describe the first integration of a noninvasive EEG-based BCI with a noninvasive FES system that enables the direct brain control ... due to SCI was able to utilize a noninvasive electroencephalogram (EEG)-based BCI to control hand grasping via FES to complete a goal-oriented task of grasping an object and moving it another...

Ngày tải lên: 19/06/2014, 08:20

... (Hycult Biotech, The Netherlands) Plasma LPS was measured using a chromogenic endpoint assay The principle of the test is based on the fact that bacteria cause intravascular coagulation in the American ... inducible cyclooxygenase (COX-2) was also assessed in control and after stress-exposure conditions An increase in COX-2 mRNA and in levels of its main product in brain, PGE2 was observed after 21 ... were removed from the skull and both cortical areas were excised from the brain and frozen at -80°C until assayed Rat brain prefrontal cortex was chosen because of its high levels of pro-inflammatory...

Ngày tải lên: 19/06/2014, 22:20

... side-to-side crosswind ‘casting’ flight can result in erroneous steering, both off-line from the toward-source direction as well as away from the direction to which the plume has swung in a shifting ... Axons from each of these classes of pheromone-component-tuned ORNs travel to the antennal lobe of the brain at the base of the antenna and arborize in their own class-specific knot of neuropil ... two antennal lobes at the bases of the antennae The preparation has been histologically cleared so that the many antennal lobe glomeruli are visible as spheroidal shapes Asterisks denote ‘ordinary’...

Ngày tải lên: 06/08/2014, 18:21

... To assess differences in tinnitus suppression between genders, an independent sampled t-test was performed with burst rTMS stimulation as dependent variable and gender as grouping variable To assess ... patient is asked to notify when the tinnitus has returned back to baseline, i.e when the tinnitus intensity is back to its initial VAS before the next rTMS frequency is applied Burst stimulation ... the brain and posterior fossa, pure tone and speech audiometry, Auditory Brainstem Response (ABR) and tympanometry Assessment of tinnitus loudness is analysed by Visual Analogue Scale (VAS) while...

Ngày tải lên: 08/08/2014, 16:23

... remainder it was similar as at baseline The mean NIHSS score on admission was 7.5 (SD: 6.18) and at discharge it was 5.94 (SD: 6.54) For patients with ischemic stroke the baseline NIHSS was 7.6 (SD: ... and brain edema in the acute phase of stroke has been little investigated Elevations of NT-PBNP were associated with hyponatremia and natriuresis in subarachnoid hemorrhage [26] as well as to ... NT-PBNP levels were measured by electrochemiluminiscence immunoassay on a Modular Analytics E170 analyzer (Roche Diagnostics) Ultrasensitive C-reactive protein (CRP-U) was measured by quantitative...

Ngày tải lên: 08/08/2014, 16:23

... associated with long-term depression [3,4,10] Imaging studies of patients with of auditory hallucinations demonstrated increased blood flow in the speech perception areas of the brain, such as ... hyperactivity in these areas has been associated with AHs Overactivation of the left temporoparietal cortex, which is critical to speech perception and is easily accessible to rTMS, has been implicated ... [17] Deep TMS was administered by a Brainsway’s H1 coil, connected to a Magstim Rapid2 stimulator (Magstim, Whitland, UK) The resting motor threshold for each participant was obtained by stimulation...

Ngày tải lên: 09/08/2014, 01:21

... Germany; U) Table The cDNA obtained was used as a template for real-time quantitative polymerase chain reaction, which was performed with the LC FastStart DNA Master SYBR GreenI® (Roche Diagnostics, ... increased in CTLs but not in freshly isolated splenic T cells Whereas the expression of TLR-4 transcripts was not seen in naive T cells, TLR-4 mRNA could be detected after stimulation and was even ... was then tested in duplicate using the enzyme-linked immunosorbent assay technique One representative experiment is shown The detection limit was 0.1 ng/ml SI, stimulation index (calculated based...

Ngày tải lên: 09/08/2014, 01:23

... Enterovirus as well as for Varicella Zoster Virus A viral culture was not performed Bacterial as well as fungal cultures of the CSF were negative The patient's symptoms worsened with increasing confusion ... patient was admitted to the outside hospital and empirical levofloxacin was started for a possible urinary tract infection, based on the presence of fever and perineal dysaesthesias An HIV test was ... an unenhanced brain CT that was suggestive of a small circumscribed brain haemorrhage The patient was transferred to our hospital for further management On admission, the patient was complaining...

Ngày tải lên: 11/08/2014, 19:21

... arterial hypertension (PAH) PAH was defined as a pulmonary artery systolic pressure (PASP) of more than 45 mm Hg The echocardiographic assessment of the PASP was made by the modified Bernoulli ... are expressed as median (25th–75th percentiles) The number of patients in whom NT-proBNP was measured on day was the same as on day (no death on day 1) LVDD, left ventricular diastolic dysfunction; ... dysfunctions were defined as the presence of LVSD, LVDD, or RVD for more than 48 hours Assay for N-terminal pro -brain natriuretic peptide Plasma levels of NT-proBNP were measured at septic shock...

Ngày tải lên: 13/08/2014, 03:20

... APACHE II score for those classified as GOS >2 was 22.1, and their mean age was 38.3 Figure Of the 27 patients included, one died of multi-organ failure in the acute phase as a result of his concomitant ... score was 20.9 and mean SAPS was 45.3 Those patients classified as GOS

Ngày tải lên: 13/08/2014, 20:21