... of 13 meta-analyses (published up to 2010), repetitive transcranial magnetic stimulation (rTMS) has a moderate, short-term antidepressant effect in the treatment of major depression The aim of ... of systematic reviews in terms of consistent reporting of all steps of such reviews, including the literature search procedures, study selection, assessment of publication bias, description of ... treatment of major depression, during the double-blind phases of RCTs Regardless of such a high interest in this topic, the antidepressant effect of rTMS was found to be moderate and rTMS parameters of
Ngày tải lên: 10/01/2020, 14:23
... Buchmann N, Gempt J, Foerschler A, Meyer B, et al Utility of presurgical navigated transcranial magnetic brain stimulation for the resection of tumors in eloquent motor areas J Neurosurg 2012;116(5):994–1001 ... al Preoperative functional mapping for rolandic brain tumor surgery: comparison of navigated transcranial magnetic stimulation to direct cortical stimulation Neurosurgery 2011;69(3):581–8 discussion ... for brain shift evaluation Med Image Anal 2004;8(4):447–64 36 Picht T, Schulz J, Vajkoczy P The preoperative use of navigated transcranial magnetic stimulation facilitates early resection of suspected
Ngày tải lên: 30/09/2020, 12:44
Genome-wide prediction of cis-regulatory regions using supervised deep learning methods
... non-protein-coding regions that were previously disregarded as junk DNA In fact, non-coding regions host a variety of cis-regulatory regions which precisely control the expression of genes Thus, ... deep learning approaches for the identification of enhancer and promoter regions in the human genome Due to their ability to discover patterns in large and complex data, the introduction of deep ... locations of promoters and enhancers has been a key focus of bioinformatics for twenty years (see reviews [6, 7]) With the advances of experimental procedures for profiling the properties of chromatin
Ngày tải lên: 25/11/2020, 15:50
Multi-scale visual analysis of time-varying electrocorticography data via clustering of brain regions
... by the Director, Office of Science, Office of Advanced Scientific Computing Research, of the U.S Department of Energy under Contract No DE-AC02-05CH11231 through the Office of Advanced Scientific ... The Regents of the University of California BMC Bioinformatics 2017, 18(Suppl 6):236 captured by electrodes placed directly on the cortical surface of the brain The correlation of electrical ... or a combination of clusters; electrical activation or deactivation of a cluster; and the birth and death of clusters In the case of epilepsy, for instance, visual analysis of the cluster data
Ngày tải lên: 25/11/2020, 17:38
Abnormalities of regional brain function in parkinson’s disease: a meta analysis of resting state functional magnetic resonance imaging studies
... this meta-analysis Of these, studies were excluded because of the following reasons: one was an abstract41; one used a method of regions of interest42; one applied an approach of support vector ... that abnormalities of regional brain function exist in Parkinson’s disease (PD) However, many resting-state functional magnetic resonance imaging (rs-fMRI) studies using amplitude of low-frequency ... in these brain regions are related to motor deficits and compensation in PD, which contribute to understanding its neurobiological underpinnings and could serve as specific regions of interest
Ngày tải lên: 19/11/2022, 11:42
identifying the appropriate time for deep brain stimulation to achieve spatial memory improvement on the morris water maze
... up-regulation of BDNF expression and neurogenesis Based on the results of this study, the use of MS-DBS during the early stage of disease may restore spatial memory impairment Keywords: Deep brain stimulation, ... occurred in the pre -stimulation group Moreover, the pre -stimulation group exhibited better recall of the platform position than the other stimulation groups An increase in the level of brain derived ... probestimulation group received stimulation for 2 h shortly before the Morris water maze probe test out of rats from the pre -stimulation group, out of rats from the training group, and out of rats
Ngày tải lên: 04/12/2022, 14:51
Cancer of the Brain and Other Central Nervous System doc
... Cerebellum, NOS, C717 - Brain Stem, C718 - Overlapping lesion of brain and C719 - Brain, NOS For other CNS cancers, primary site of tumor is classified as the following: BRAIN: C700 - Cerebral ... 25 Cancer of the Brain and Nervous System Table 25.3: Cancer of the Brain: Race, Sex, Age (20+), Grade and Tumor Size, 12 SEER Areas, 1988-2001 Characteristics Total Brain Cases % of Cases Relative ... occurring in the frontal lobes (25.8% of total), temporal lobe (20.1% of total), parietal lobe (14.6% of total) and overlapping lesions of the brain (19.8% of total) were the most common Relative
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of b-oxidation doc
... the lack of effect of adipophilin overexpression on cellular triglyceride content in macrophages loaded with VLDL The lipid-droplet content of macrophages was increased by overexpression of adipophilin ... by inhibition of b-oxidation and stimulation of long-chain fatty acid incorporation into triglycerides Adipophilin expression in THP-1 macrophages altered the cellular content of different lipids ... lesions Lipid loading of macrophages in vitro can be achieved by chemical modification of the apolipopro- tein B component of low-density lipoprotein (LDL), aggregation of LDL induced by either
Ngày tải lên: 23/03/2014, 10:21
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... conservation of the magnetic anisotropies of low-spin hemin with His/cyanide ligation The 10° tilt of the major magnetic or z-axis is shown to be consistent with the % 10° tilt of the Fe-CN vector ... R.J.P (1985) Comparison of the solution and crystal structures of mitochondrial cytochrome c Analysis of paramagnetic shifts in the nuclear magnetic resonance spectrum of ferricytochrome c J Mol ... projection of the tilt of the z axis on the x¢, y¢ plane (defined direction of tilt of z and the x¢ axis), and j % a + c defines the location of the rhombic (x, y) axes The orientation of the axial His
Ngày tải lên: 23/03/2014, 17:22
Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc
... by results of body composition analysis Our interpretation of these data is that chronic inhibition by B[a]P of physiological b-adrenergic and ACTH stimulation caused a reduction of energy expenditure ... little has been documented on the effect of B[a]P on adipocyte function, one of the main sites of storage We therefore decided to address the question of B[a]P toxicity on adipocytes, and specifically ... Upon withdrawal of this PAH, the excess weight gain was not corrected Our data indicate that inhibition of lipolysis by B[a]P proceeds via direct inhibition of the early step of b-adrenergic
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: Structure, mRNA expression and linkage mapping of the brain-type fatty acid-binding protein gene (fabp7 ) from zebrafish (Danio rerio) potx
... of adult avian and fish brain The temporal expression of the B-FABP gene reported here (Fig 4C) and our previous report of its expression in the periventricular grey zone of the optic tectum of ... various areas of the nervous system of the guppy, Lebistes J Comp Neurol 194, 291–301 Rousselot, P., Heintz, N & Nottebohm, F (1997) Expression of brain lipid binding protein in the brain of the adult ... generally thought to be regulated by a cascade of transcription factors Analysis of the sequence 5¢ upstream of exon of the B-FABP gene revealed a number of potential cis-acting regulatory elements,
Ngày tải lên: 31/03/2014, 07:20
scientific american day in the life of your brain
... IN LIFE of Your Brain THE DREAMING EATING ENERGETIC DROWSY ANXIOUS MAD AS HELL SEXY SLEEPING HORSTMAN The Scientific American DAY in the LIFE of YOUR BRAIN “Day in the Life of Your Brain takes ... [...]... overall brain is often described in three parts, from the bottom up, just the way your brain evolved over millennia The primitive brain the brain stem or hindbrain—that sits ... your brain is teaching old neurons new tricks and even making new neurons When some sections of the brain go dark, other parts of the brain can learn to take over part of those
Ngày tải lên: 12/05/2014, 16:39
báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx
... effectiveness of systemic chemotherapy for the treatment of malignant brain tumors and the therapeutic implications thereof Background Malignant brain tumors consist of high-grade primary brain tumors ... limit of pore size in the BBTB of the microvasculature of early, less mature and smaller malignant brain tumor colonies is to nanometers lower than that of the BBTB of the microvasculature of late, ... Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood -brain barrier disruption Proceedings of the National Academy of Sciences of the United States of America
Ngày tải lên: 18/06/2014, 15:20
báo cáo sinh học:" Intent to migrate among nursing students in Uganda: Measures of the brain drain in the next generation of health professionals" pot
... Measures of the brain drain in the next generation of health professionals Lisa Nguyen*1, Steven Ropers1, Esther Nderitu2, Anneke Zuyderduin, Sam Luboga3 and Amy Hagopian4 Address: 1School of Medicine, ... University of Washington, Seattle, USA, 2Department of Nursing, Aga Khan University School of Nursing, Kampala, Uganda, 3Department of Medicine, Makerere University, Kampala, Uganda and 4Department of ... achieved with the continued exodus of nurses from African countries [2] Africa, with 24 percent of the global burden of disease, employs only three percent of all health professionals [5] Nurses in Africa
Ngày tải lên: 18/06/2014, 17:20
Báo cáo sinh học: " Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro" docx
... separation of 5S protomers and 14S pentamers The amount of radioactivity at the bottom of the tubes of the gradients was not determined (A) Comparison of samples obtained in the absence or presence of ... presence of an intact RNA binding site within the 3Cpro domain of 3CDpro In addition, the integrity of interface I in the 3Dpol domain of 3CDpro is required for efficient production of mature ... addition of extra 3CDpro Our results indicate that the stimulation of RNA synthesis and virus maturation by 3CDpro in vitro is dependent on the presence of a VPg-linked RNA template Page of 19 (page
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation" pptx
... Aging and Brain Repair, Department of Neurosurgery, University of South Florida College of Medicine, Tampa, FL 33613, USA and 6 Department of Pharmacology and Therapeutics, University of South ... if the stimulation of CB 2 could modulate the capacity of microglial cells to phagocytise Aβ 1–42 peptide using a phagocytosis assay. Results: We found that the selective stimulation of cannabinoid ... resulting from the activation of brain mononuclear phagocyte cells, called microglial cells[1]. Because increased proliferation of microglial cells is seen in brains of patients with multiple sclerosis
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Anandamide inhibits Theiler’s virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors" pdf
... inhibition of VCAM-1 expression in brain endothelial cell cultures was mediated by activation of CB1 receptors The study of leukocyte transmigration confirmed the functional relevance of VCAM-1 ... immunofluorescence microphotograps per level were analyzed using the Image J software designed by National Institutes of Health Results are presented as intensity of staining per vessel in case of ... the effect of AEA on the adhesion of leukocytes interferes on leukocyte transmigration through the BBB model As expected TMEV-infection of brain endothelial cells increased the number of leukocytes
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Lateral fluid percussion injury of the brain induces CCL20 inflammatory chemokine expression in rats" pdf
... Quantitation showed that the number of IB4-positive cells was significantly increased in each of these brain regions 24 h after TBI, while number of IB4+ cells in these regions 48 h post-TBI did not ... LFPI-induced brain Page 15 of 16 injury evoked an inflammatory reaction in the injured brain and attracted a population of activated microglia resulting in further damage of the brain The fact ... response in a rat model of TBI The LFPI model of TBI used in this study offers an excellent model of clinical contusion without skull fracture [11,12], expressing the features of the primary injury
Ngày tải lên: 19/06/2014, 22:20
Báo cáo toán học: " Structural, optical and magnetic studies of manganese-doped zinc oxide hierarchical microspheres by self-assembly of nanoparticles" docx
... Novel magnetic behavior of Mn-doped ZnO hierarchical hollow spheres J Nanopart Res 2012 14:659 48 Lin X, Zhu Y, Shen W: Synthesis and optical and magnetic properties of diluted magnetic ... becomes deeper and deeper with increasing Mn. The phase purity and crystal structure of the pristine ZnO and Mn-doped ZnO for various doping levels have been analyzed by XRD. All of the diffraction ... intensity of the diffraction peaks decreases, and the width broadens due to the formation of smaller grain diameters as a result of an increase in disorder on Mn 2+ doping. Also, the evolution of
Ngày tải lên: 20/06/2014, 20:20
Báo cáo y học: " Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study" pdf
... cross-modulation can be studied through the analysis of the electromyographic responses to transcranial magnetic stimulation (TMS) and of the effects of voluntary and involuntary muscle activations ... bottom) to transcranial magnetic stimulation applied anterolaterally during expiration in one normal subject (A) and one patient with OSAS (B) The arrow indicates the time of stimulation Page of 10 ... genioglossus and diaphragm responses to transcranial magnetic stimulation in awake humans Exp Physiol 2007, 92:739-747 Aminoff MJ, Sears TA: Spinal integration of segmental, cortical and breathing...
Ngày tải lên: 12/08/2014, 14:20
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