cycle insulin secretion fatty acid oxidation and respiration
Báo cáo khoa học: Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans pot
Ngày tải lên :
22/03/2014, 16:21
... R J A Wanders et al Fatty acid oxidation disorders Fig Schematic diagram depicting the different mechanisms by which fatty acids can be oxidized (see text) General aspects of fatty acid oxidation ... compilation ª 2010 FEBS 183 Fatty acid oxidation disorders R J A Wanders et al Table The mitochondrial and peroxisomal beta -oxidation deficiencies Mitochondrial fatty acid oxidation disorders Mutant ... peroxisomal a -oxidation of phytanic acid is pristanic acid which first undergoes three cycles of b -oxidation in the peroxisome to produce propionyl-CoA (in the first and third cycle of b -oxidation) and acetyl-CoA...
- 13
- 475
- 0
báo cáo khoa học: "Fatty acid profiles and their distribution patterns in microalgae: a comprehensive analysis of more than 2000 strains from the SAG culture collection" docx
Ngày tải lên :
11/08/2014, 11:21
... α-linolenic acid; ARA: Arachidonic acid; CVA: canonical variance analysis; DHA: docosahexaenoic acid; DMOX: 4, 4-dimethyloxaline; EPA: Eicosapentaenoic acid; FA: fatty acid; FAME: fatty acid methyl ... esters of FAs Out of the 76 fatty acids, 36 substances were identified by their mass spectrum and by retention time according to a standard substance, and the other 40 fatty acids were identified by ... Trebouxiophyceae (arrowheads) and Ulvophyceae (circles) as based on their fatty acid distribution patterns using Canonical Variates Analysis Both vectors correspond to variables (fatty acids) correlated...
- 16
- 617
- 0
Maternal polyunsaturated fatty acid status and offspring allergic disease up to the age of 18 months
Ngày tải lên :
30/09/2015, 10:11
... ABBREVIATIONS SFA Saturated fatty acid MUFA Monounsaturated fatty acid PUF Polyunsaturated fatty acid LA Linoleic acid EPA Eicosapentaenoic acid DHA Docosahexaenoic acid IMDR Acceptable macronutrient ... dietary fatty 347 acids, the fatty acid composition of plasma lipid fractions change accordingly 348 (73) Traditionally, fatty acids measured in erythrocytes were thought to 349 represent fatty acid ... 1.4 Mechanisms linking PUFA and allergy 15 1.4.1 Mechanisms of allergy 15 1.4.2 n-6 fatty acids and allergic inflammation 16 1.4.3 n-3 fatty acids and allergic inflammation...
- 71
- 188
- 0
Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt
Ngày tải lên :
23/03/2014, 12:20
... Genetic defects in fatty acid oxidation (Eur J Biochem 271) 471 Table Transporter proteins and enzymes involved in the mitochondrial saturated fatty acid oxidation FATP, fatty acid transport protein; ... MCAD and short-chain acyl-CoA dehydrogenase (SCAD) Types of sequence variations in fatty acid oxidation genes The first level of analysis of the genotype–phenotype relationship in fatty acid oxidation ... enzymes of fatty acid oxidation The draft sequence of the human genome was published in 2001 [7,8] and the assembly of large contigs and the annotation of genes makes it possible to find gene and genome...
- 13
- 407
- 0
Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas
Ngày tải lên :
05/09/2013, 10:17
... japonica We found about 30 kinds of fatty acids in the leaves and stems and about 36 kinds of fatty acids in the roots and rhizomes of Z japonica We focused on the fatty acid content of Z japonica , ... such as bacteria, periphyton and sessile animals We define the fatty acids with > 5% content as dominant fatty acids and Fig shows the dominant fatty acids in the leaves and stems of Z japonica in ... NG KT KG Fatty acid content (%) Fatty acid content (%) However, we think that the characteristics of the fatty acid structure in the leaves and stems differ from those of the roots and rhizomes...
- 9
- 614
- 2
Effect of unsaturated fatty acid esters of biodiesel fuels on combustion, performance and emission characteristics of a DI diesel engine
Ngày tải lên :
05/09/2013, 15:28
... of Energy and Environment (IJEE), Volume 1, Issue 3, 2010, pp.411-430 427 properties and fatty acid composition on CO and HC emissions The correlation analysis reveals that the CO and HC emissions ... International Journal of Energy and Environment (IJEE), Volume 1, Issue 3, 2010, pp.411-430 415 Table Fatty acid methyl composition of different biodiesel fuels Fatty acid methyl ester composition ... hydroperoxides increases the risk of polymerization and acidification and of the appearance of insoluble sediments and gums, which can lead to filter plugging and deposits in the fuel systems Esterified...
- 20
- 483
- 0
THÀNH PHẦN hợp CHẤT AXÍT béo và CAROTENOID của gấc fatty acid and carotenoid composition of gac (momordica cochinchinensisspreng) fruit
Ngày tải lên :
09/02/2014, 00:08
... Fatty Acid and Carotenoids in Gac Fruit MATERIALS AND METHODS Fatty Acid Analysis Materials Gac fruit were purchased from two Asian markets (Vinh Phat and Shun Fat) in Sacramento, ... relative standard deviation, % vaccenic (in two fruit), R-linolenic, and eicosa-11-eneoic acids were also detected The fatty acid composition of the aril and seed are interesting, and they reflect ... Vitamin E and omega-3 fatty acids (21), although our data show only 0.3-0.8% linolenic acid (Table 2) Seeds of tropical plants may contain high levels of saturated fatty acids, with palmitic acid...
- 6
- 886
- 4
Tài liệu Báo cáo " Effect of Sweet potato (Ipomoea batatas (L.) Lam) leaf extract on hypoglycaemia, blood insulin secretion, and key carbohydrate metabolic enzymes in expermentally obese and STZ-induced diabetic mice " pptx
Ngày tải lên :
12/02/2014, 17:20
... on blood fasting glucose level and plasma insulin secretion in type 2-diabetic mice Table Effect of extract fractions on blood fasting glucose and plasma insulin secretion in obese-diabetic mice ... changes in blood fasting glucose, plasma insulin and lipid parameters, such as TC, TG, HDL, and PI, in comparison with untreated ND fed mice Therefore, obesity and insulin resistance were the important ... significant Results and discussion 3.1 Body weight, biochemical parameters of ND and HFD fed mice Table indicated that the body weight, blood lipid parameters, such as TC, TG, LDTc, and plasma insulin concentration...
- 7
- 572
- 0
Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt
Ngày tải lên :
19/02/2014, 08:20
... cation ligands are main-chain oxygen atoms, and three are the side-chain oxygen atoms of N296, E342 and S387 The glutamic acid and asparagine residues are conserved among known KAS I and KAS II ... mutated KAS I structures ˚ The distance between H333 Ne and C163 Sc is 3.2 A ˚ in the native and fatty acid complex, and 3.1 A respectively, and infers that H333 Ne donates a hydrogen bond to the ... mutants K328H and K328R are more efficient (247% and 227%), the acidic mutant K328E is less efficient (31%), and the bulky mutants K328F and K328I are similar to the wild-type (91% and 117%) Increasing...
- 16
- 450
- 0
Báo cáo khoa học: Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic b-islets ppt
Ngày tải lên :
06/03/2014, 00:21
... Although, in these transgenic mice, there was no change in insulin secretion under fed and starved conditions, there was a dramatic effect on insulin secretion in response to glucose challenge (GSIS) ... expression in insulin- secreting cells b-TC-6 cells were transfected with 60 nM of precursors of mir-control and mir-9 (A) and 1.5 lg of pSuper and pSuper-mir-9 plasmids (B, C) for 72 and 24 h, respectively ... antibodies (Sigma cat nos A0545 and A2554) and Lumi-Light Western Blotting Substrate (Roche cat no 12 015 196 001) were used to visualize the bands Insulin ELISA Sera and culture supernatants from...
- 8
- 404
- 0
Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio) pptx
Ngày tải lên :
07/03/2014, 06:20
... protection of enzymes and membranes from the detergent effects of excess fatty acids by sequestering them, and (d) modulation of cell growth and differentiation by transport of fatty acids to the nucleus ... they were initially isolated, e.g livertype fatty acid- binding protein (L-FABP), brain-type fatty acid- binding protein (B-FABP), intestinal-type fatty acid- binding protein (I-FABP), etc However, ... (1972) A binding protein for fatty acids in cytosol of intestinal mucosa, liver, myocardium, and other tissues Science 177, 56–58 Haunerland NH & Spener F (2004) Fatty acid- binding proteins – insights...
- 10
- 379
- 0
Báo cáo khoa học: Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx
Ngày tải lên :
07/03/2014, 12:20
... (84%) and amino acids (86%) with spherulin 3a (Figs and 2), the most abundant encystment-specific protein [16], and identities with sequences of bc-crystallins (Fig 2) The total number of amino acids ... NcoI and SpeI at 37 °C for 1.5 h and was analysed on a 2% agarose gel The purified DNA fragment was used as standard Total RNA was isolated from cells of the different stages in the life cycle, and ... sulfuric acid and incubated at 95 °C for 1.5 h Then the acid was neutralized with 50 lL of m NaOH The other tube was kept on ice and was used to measure the amount of endogenous malate Polymalic acid...
- 10
- 639
- 0
Báo cáo khoa học: Escherichia coli cyclopropane fatty acid synthase Mechanistic and site-directed mutagenetic studies potx
Ngày tải lên :
07/03/2014, 16:20
... Pollard, M & Ohlrogges, J.B (2002) Carbocyclic fatty- acids in plants: Biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of Sterculia foetida Proc Natl Acad ... cyclopropane fatty acids in Escherichia coli Biochimica Biophysica Acta 348, 6375 Taylor, F.R & Cronan J.E (1979) Cyclopropane fatty acid synthase of Escherichia coli Stabilization, purication, and interaction ... Cyclopropane fatty acid synthase from Escherichia coli Methods Enzymol 71, 133139 Grogan, D.W & Cronan J.E (1984) Cloning and manipulation of the Escherichia coli cyclopropane fatty acid synthase...
- 10
- 335
- 0
Báo cáo khoa học: Differential tissue-specific distribution of transcripts for the duplicated fatty acid-binding protein 10 (fabp10) genes in embryos, larvae and adult zebrafish (Danio rerio) docx
Ngày tải lên :
16/03/2014, 00:20
... (1993) Fatty acidbinding protein and its relation to fatty acid oxidation Mol Cell Biochem 123, 101–106 15 Glatz JF & van der Vusse GJ (1996) Cellular fatty acidbinding proteins: their function and ... uptake and utilization of fatty acids, intracellular targeting of fatty acids to specific organelles and metabolic pathways, and the protection of cellular structures from the detergent effects of fatty ... & Hsu KT (2002) Similar mechanisms of fatty acid transfer from human and rodent fatty acid- binding proteins to membranes: liver, intestine, heart muscle and adipose tissue FABPs Mol Cell Biochem...
- 11
- 402
- 0
Báo cáo khoa học: Fatty acid composition of chylomicron remnant-like particles influences their uptake and induction of lipid accumulation in macrophages pot
Ngày tải lên :
16/03/2014, 12:20
... the particular type of fatty acid predominating in the oil, but also contained a complex mixture of other fatty acids, as occurs in vivo As might be expected, the fatty acid composition of CRLPs ... macrophages exhibit alterations in incorporation and oxidation of fatty acids Lipids 34, 1193–1197 36 Yu KC & Cooper AD (2001) Postprandial lipoproteins and atherosclerosis Front Biosci 6, D332–D354 ... chromatography Data are expressed as gÆ(100 g total fatty acids))1 and are the mean ± SEM from three separate preparations ND, none detected CRLPs Fatty acid Palm 14:0 16:0 16:1 n)7 18:0 18:1 n)9 18:1...
- 9
- 349
- 0
Báo cáo khoa học: Two novel Mesocestoides vogae fatty acid binding proteins – functional and evolutionary implications doc
Ngày tải lên :
23/03/2014, 07:20
... fluorescent fatty acid transfer from adipocyte and heart fatty acid binding proteins by acceptor membrane lipid composition and structure J Biol Chem 269, 10517–10523 47 Hsu KT & Storch J (1996) Fatty acid ... THMSM, Maatman RGHJ & Prinsen CFM (1993) Structural and functional aspects of cytosolic fatty- acid binding proteins Prostaglandins Leukot Essent Fatty Acids 49, 887–906 FEBS Journal 275 (2008) 107–116 ... cloning and expression of a novel keratinocyte protein [psoriasis-associated fatty acid- binding protein (PA-FABP)] that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid- binding...
- 10
- 342
- 0
Báo cáo khoa học: Characterization of a hemocyte intracellular fatty acid-binding protein from crayfish (Pacifastacus leniusculus) and shrimp (Penaeus monodon) pdf
Ngày tải lên :
23/03/2014, 10:21
... Vertebrate FABPs are involved in cellular fatty acid transport and utilization and compartmentalization of intracellular fatty acid storage, and also in fatty acidinduced regulation of gene expression ... of RA and ⁄ or fatty acid molecules The biological roles of these proteins span over a wide range of processes such as transport, cellular uptake and cytoplasmic trafficking of fatty acids, and ... Oleic acid and stearic acid solutions were prepared as described by Stremmel & Berk [38] Briefly, the fatty acids (Sigma) were dissolved at 50 lm in 0.1 m NaOH at 37 °C, and a solution of 2.5 mm fatty...
- 11
- 545
- 0
Báo cáo khoa học: Differential regulation of fatty acid amide hydrolase promoter in human immune cells and neuronal cells by leptin and progesterone pdf
Ngày tải lên :
30/03/2014, 15:20
... (2002) Endocannabinoids in the immune system and cancer Prostaglandins Leukot Essent Fatty Acids 66, 319–332 24 Cravatt, B.F & Lichtman, A.H (2003) Fatty acid amide hydrolase: an emerging therapeutic ... Francke, U (1998) Conserved chromosomal location and genomic structure of human and mouse fatty- acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation Genomics 54, ... Fig Effect of leptin and progesterone on FAAH activity and expression (A) Effect of leptin on the activity of FAAH in human U937 and CHP100 cells and on the protein content and the mRNA of FAAH...
- 11
- 468
- 0
Báo cáo khoa học: Structure, mRNA expression and linkage mapping of the brain-type fatty acid-binding protein gene (fabp7 ) from zebrafish (Danio rerio) potx
Ngày tải lên :
31/03/2014, 07:20
... percentage amino acid identity between zebrafish and human, mouse and pufferfish B-FABP is 83%, 76% and 83%, respectively The percentage amino acid identity between zebrafish and human and mouse is ... lipid-binding proteins and their genes Annu Rev Nutr 17, 277–303 25 Wu, Q., Andolfatto, P & Haunerland, N.H (2001) Cloning and sequence of the gene encoding the muscle fatty acid binding protein ... testes and between 50 and 160 times higher in brain than in muscle, intestine and heart No product was generated by qRT-PCR from liver, ovary, skin and kidney RNA Both conventional RT-PCR and qRT-PCR...
- 11
- 366
- 0
Báo cáo khoa học: Structure, linkage mapping and expression of the heart-type fatty acid-binding protein gene (fabp3 ) from zebrafish (Danio rerio) pot
Ngày tải lên :
31/03/2014, 07:20
... transportation and utilization of fatty acids in cardiac muscle [4,5] However, H-FABP is also abundant in tissues that not use fatty acids as an energy source such as mammary gland and developing ... inhibitor/heart -fatty acid- binding protein Gene 147, 237–242 10 Prinsen, C.F & Veerkamp, J.H (1996) Fatty acid binding and conformational stability of mutants of human muscle fatty acidbinding protein ... of fatty acids within the oocyte The accumulation of fatty acids may be sequestered by FABP to prevent cytotoxicity to the cell, and transported by FABP to sites of triglyceride synthesis and/ or...
- 12
- 505
- 0