... Chapter 056. Cutaneous Drug Reactions (Part 1) Harrison's Internal Medicine > Chapter 56. Cutaneous Drug Reactions CUTANEOUS DRUG REACTIONS: INTRODUCTION Cutaneous reactions are ... adverse cutaneous reactions. INCIDENCE OF CUTANEOUS REACTIONS Several large cohort studies established that acute cutaneous reaction to drugs affected about 3% of hospital inpatients. Reactions usually ... frequent adverse reactions to drugs. Every physician will see patients suffering from them. Most are benign, but a few can be life-threatening. Prompt recognition of severe reactions, drug withdrawal,...
Ngày tải lên: 07/07/2014, 01:20
... frequent in CD4+ clones while CD8+ Chapter 056. Cutaneous Drug Reactions (Part 2) PATHOGENESIS OF DRUG REACTIONS Untoward cutaneous responses to drugs can arise as a result of immunologic ... preventive measures. Immunologic Drug Reactions For most acute drug eruptions, benign or severe, accumulated data suggest an immunologic basis. In the last 10 years drug- specific T cell clones were ... the most frequent causes of IgE- dependent reactions to drugs, which require prior sensitization. Release of mediators is triggered when polyvalent drug protein conjugates cross-link IgE molecules...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 3) docx
... PRESENTATION OF CUTANEOUS DRUG REACTIONS Nonimmune Cutaneous Reactions EXACERBATION OR INDUCTION OF DERMATOLOGIC DISEASES stimulation of T cells by medications leads to reactions that are ... neutrophil-mediated drug reaction. One may therefore assume that the final pattern of drug eruptions results both from the nature of effectors—cytotoxic T cells in blistering reactions, chemokines in reactions ... and response. GENETIC FACTORS AND CUTANEOUS DRUG REACTIONS Specific genetically determined defects in the ability of an individual to detoxify toxic reactive drug metabolites predispose such...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 3) pps
... in patients receiving cytotoxic drugs can be increased by exposure to sunlight. Chapter 056. Cutaneous Drug Reactions (Part 3) PIGMENTATION CHANGES Drugs, either systemic or topical, ... Development of the syndrome is unrelated to drug dose, and the course is not altered by discontinuation of the drug after onset of the eruption. Warfarin reactions are associated with protein C ... DRUG- INDUCED HAIR DISORDERS Drug- Induced Hair Loss Medications may affect hair follicles at two different phases of their cycle. Anagen effluvium occurs within days of drug administration,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 5) doc
... helpful. In addition to drug Chapter 056. Cutaneous Drug Reactions (Part 5) Onychomadesis Onychomadesis is caused by temporary arrest of nail matrix mitotic activity. Common drugs reported to ... rarer in Caucasians. Immune Cutaneous Reactions: Benign MACULOPAPULAR ERUPTIONS Morbilliform or maculopapular eruptions are the most common of all drug- induced reactions, often start on the ... symptoms. Certain drugs, such as NSAIDs, ACE inhibitors, angiotensin II antagonists, and radiographic dyes, may induce urticarial reactions, angioedema, and anaphylaxis in the absence of drug- specific...
Ngày tải lên: 07/07/2014, 01:20
R INTE S OF MEDIC REPORTING ADVERSE DRUG REACTIONS DEFINITIONS OF TERMS AND CRITERIA FOR THEIR USE ppt
... of skin lesions and therefore encompassing virtually all cutaneous adverse reactions. As a general rule, in reporting cutaneous drug reactions specific terms should be used, but only when the ... of the skin. Photosensitivity reactions may be pleomorphic and include dermatitis-like reactions. Phototoxic reactions, which are non-immunological events caused by drugs or chemicals, are far ... for Reporting Adverse Drug Reactions 9 Skin and Appendages Disorders (SOC 0100) 9 Introduction 9 Terms 10 Dermatitis (Eczema) 10 Dermatitis exfoliative 10 Fixed drug eruption. 11 Lichenoid drug eruption...
Ngày tải lên: 07/03/2014, 10:20
Women and Adverse Drug Reactions Reporting in the Canadian Context pot
... voluntary reporting of adverse drug reactions was inadequate, the jury’s key recommendation called for a national system for the mandatory reporting of adverse drug reactions. Mandatory reporting, ... adverse drug reactions. But as , Dr Joel Lexchin - a Toronto physician who has extensively researched the drug industry - has said, Canada’s regulatory system is “good at not letting drugs on ... adverse drug reactions in Canada, using a 1:10 ratio of the population of Canada to that of the US, would total 7,600 annually – 10% of the estimated 76,000 deaths due to adverse drug reactions...
Ngày tải lên: 22/03/2014, 11:20
Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) pdf
... 1báo cáo về bệnh thận nhiễm độc. (theo Reactions Weekly; Số 1018; 11/9/2004) TCNCYH 36 (3) - 2005 91 Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) G.S. Hoàng Tích Huyền Bộ...
Ngày tải lên: 25/03/2014, 05:20
Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) docx
... TCNCYH 29 (3) - 2004 Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) GS.TSKH. Hoàng Tích Huyền* 1. Gatifloxacin và chuyển hoá bất thờng của ... cảm, lú lẫn, thao thức khi đó phải ngừng ngay mefloquin và báo cáo với thầy thuốc". (Theo Reactions Weekly, 01/11/2003, số 975). 4. Doxycyclin gây viêm loét thực quản (Australia, Tân Tây...
Ngày tải lên: 03/04/2014, 00:20
Báo cáo y học: " Parkinsonism caused by adverse drug reactions: a case series." pps
Ngày tải lên: 11/08/2014, 00:23
cach-tCách tạo slide thuyết trình ấn tượng bằng powerpointao-slide-thuyet-trinh-an-tuong-bang-powerpoint.pdf
Ngày tải lên: 06/08/2012, 16:21