cutaneous drug reactions pdf
Chapter 056. Cutaneous Drug Reactions (Part 1) potx
... Chapter 056. Cutaneous Drug Reactions (Part 1) Harrison's Internal Medicine > Chapter 56. Cutaneous Drug Reactions CUTANEOUS DRUG REACTIONS: INTRODUCTION Cutaneous reactions are ... adverse cutaneous reactions. INCIDENCE OF CUTANEOUS REACTIONS Several large cohort studies established that acute cutaneous reaction to drugs affected about 3% of hospital inpatients. Reactions usually ... frequent adverse reactions to drugs. Every physician will see patients suffering from them. Most are benign, but a few can be life-threatening. Prompt recognition of severe reactions, drug withdrawal,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 2) pps
... frequent in CD4+ clones while CD8+ Chapter 056. Cutaneous Drug Reactions (Part 2) PATHOGENESIS OF DRUG REACTIONS Untoward cutaneous responses to drugs can arise as a result of immunologic ... preventive measures. Immunologic Drug Reactions For most acute drug eruptions, benign or severe, accumulated data suggest an immunologic basis. In the last 10 years drug- specific T cell clones were ... the most frequent causes of IgE- dependent reactions to drugs, which require prior sensitization. Release of mediators is triggered when polyvalent drug protein conjugates cross-link IgE molecules...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 3) docx
... PRESENTATION OF CUTANEOUS DRUG REACTIONS Nonimmune Cutaneous Reactions EXACERBATION OR INDUCTION OF DERMATOLOGIC DISEASES stimulation of T cells by medications leads to reactions that are ... neutrophil-mediated drug reaction. One may therefore assume that the final pattern of drug eruptions results both from the nature of effectors—cytotoxic T cells in blistering reactions, chemokines in reactions ... and response. GENETIC FACTORS AND CUTANEOUS DRUG REACTIONS Specific genetically determined defects in the ability of an individual to detoxify toxic reactive drug metabolites predispose such...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 3) pps
... in patients receiving cytotoxic drugs can be increased by exposure to sunlight. Chapter 056. Cutaneous Drug Reactions (Part 3) PIGMENTATION CHANGES Drugs, either systemic or topical, ... Development of the syndrome is unrelated to drug dose, and the course is not altered by discontinuation of the drug after onset of the eruption. Warfarin reactions are associated with protein C ... DRUG- INDUCED HAIR DISORDERS Drug- Induced Hair Loss Medications may affect hair follicles at two different phases of their cycle. Anagen effluvium occurs within days of drug administration,...
Ngày tải lên: 07/07/2014, 01:20
Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) pdf
... 1báo cáo về bệnh thận nhiễm độc. (theo Reactions Weekly; Số 1018; 11/9/2004) TCNCYH 36 (3) - 2005 91 Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) G.S. Hoàng Tích Huyền Bộ...
Ngày tải lên: 25/03/2014, 05:20
Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf
... of pyruvate, the various biochemical reactions involving pyruvate are the most intensely studied and are well understood. Thus, they serve as prototypical reactions for the enzymic oxidative conversion ... MINIREVIEW Reaction mechanisms of thiamin diphosphate enzymes: redox reactions Kai Tittmann Albrecht-von-Haller-Institut fu ¨ r Pflanzenwissenschaften und Go ¨ ttinger ... February 2009) doi:10.1111/j.1742-4658.2009.06966.x Amongst a wide variety of different biochemical reactions in cellular car- bon metabolism, thiamin diphosphate-dependent enzymes catalyze the oxi- dative...
Ngày tải lên: 18/02/2014, 08:20
R INTE S OF MEDIC REPORTING ADVERSE DRUG REACTIONS DEFINITIONS OF TERMS AND CRITERIA FOR THEIR USE ppt
... of skin lesions and therefore encompassing virtually all cutaneous adverse reactions. As a general rule, in reporting cutaneous drug reactions specific terms should be used, but only when the ... of the skin. Photosensitivity reactions may be pleomorphic and include dermatitis-like reactions. Phototoxic reactions, which are non-immunological events caused by drugs or chemicals, are far ... for Reporting Adverse Drug Reactions 9 Skin and Appendages Disorders (SOC 0100) 9 Introduction 9 Terms 10 Dermatitis (Eczema) 10 Dermatitis exfoliative 10 Fixed drug eruption. 11 Lichenoid drug eruption...
Ngày tải lên: 07/03/2014, 10:20
Plant physiology - Chapter 8 Photosynthesis: Carbon Reactions pdf
... Chapter 8 Light Light reactions Chlorophyll Carbon reactions Triose phosphates O 2 H 2 O CO 2 + H 2 O (CH 2 O) n NADP + ADP P i NADPH ATP + + FIGURE 8.1 The light and carbon reactions of photosynthe- sis. ... chloroplasts. These stroma reactions were long thought to be independent of light and, as a consequence, were referred to as the dark reactions. However, because these stroma-localized reactions depend ... oxidative reactions. The flow of carbon, nitrogen and oxygen are indi- cated in black, red and blue, respectively. See Table 8.2 for a description of each numbered reaction. Photosynthesis: Carbon Reactions...
Ngày tải lên: 07/03/2014, 20:20
Women and Adverse Drug Reactions Reporting in the Canadian Context pot
... voluntary reporting of adverse drug reactions was inadequate, the jury’s key recommendation called for a national system for the mandatory reporting of adverse drug reactions. Mandatory reporting, ... adverse drug reactions. But as , Dr Joel Lexchin - a Toronto physician who has extensively researched the drug industry - has said, Canada’s regulatory system is “good at not letting drugs on ... adverse drug reactions in Canada, using a 1:10 ratio of the population of Canada to that of the US, would total 7,600 annually – 10% of the estimated 76,000 deaths due to adverse drug reactions...
Ngày tải lên: 22/03/2014, 11:20
Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) docx
... TCNCYH 29 (3) - 2004 Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) GS.TSKH. Hoàng Tích Huyền* 1. Gatifloxacin và chuyển hoá bất thờng của ... cảm, lú lẫn, thao thức khi đó phải ngừng ngay mefloquin và báo cáo với thầy thuốc". (Theo Reactions Weekly, 01/11/2003, số 975). 4. Doxycyclin gây viêm loét thực quản (Australia, Tân Tây...
Ngày tải lên: 03/04/2014, 00:20
báo cáo hóa học:" Confronting TB/HIV in the era of increasing anti-TB drug resistance" pdf
... Anti-Tuberculosis Drug Resistance in the world Report No 4. The WHO/IUATLD Global project on anti-tuberculosis drug resistance surveillance . WHO/HTM/TB/2008.394 35. Koenig R: Drug- resistant tuberculosis. ... effect of anti-tuberculous drugs on liver function. J Postgrad Med 2006, 52:92-6. 30. MMWR: 55:11. 2006, March 24 31. Gandhi NR, Moll A, Sturm AW, et al.: Extensively drug- resistant tuberculosis ... Infec- tion and Multi drug resistant tuberculosis – the perfect storm. Journal of Infectious Diseases 2007, 196:S86-107. 33. Dubrovina I, Miskinis K, Lyepshina S, et al.: Drug resistant tubercu- losis...
Ngày tải lên: 20/06/2014, 08:20
Báo cáo hóa học: " Self-Assembled Polymeric Micellar Nanoparticles as Nanocarriers for Poorly Soluble Anticancer Drug Ethaselen" pdf
... chain length. In addition, similar to drug- loaded micelles reported earlier [15, 27], the size of drug- loaded micelles was about 10 nm bigger than that of drug- free micelles, suggesting that ethaselen ... influence the pharmacokinetics of drugs [39, 40], while much more drug would be accumulated in the solid tumor region due to delay of the circulation time of drugs for polymeric micelles [22, ... loss, resulting from the toxic effect of the drug, indicating that this micelle-based drug delivery system could reduce unwanted side effects of anticancer drugs during cancer therapy. Overall, ethaselen-loaded...
Ngày tải lên: 22/06/2014, 00:20
Báo cáo y học: " Parkinsonism caused by adverse drug reactions: a case series." pps
Ngày tải lên: 11/08/2014, 00:23
báo cáo khoa học: " Route of administration for illicit prescription opioids: a comparison of rural and urban drug users" pdf
Ngày tải lên: 11/08/2014, 18:20