cutaneous drug reactions pdf
Chapter 056. Cutaneous Drug Reactions (Part 1) potx
Ngày tải lên :
07/07/2014, 01:20
...
Chapter 056. Cutaneous
Drug Reactions
(Part 1)
Harrison's Internal Medicine > Chapter 56. Cutaneous Drug Reactions
CUTANEOUS DRUG REACTIONS: INTRODUCTION
Cutaneous reactions are ... adverse cutaneous reactions.
INCIDENCE OF CUTANEOUS REACTIONS
Several large cohort studies established that acute cutaneous reaction to
drugs affected about 3% of hospital inpatients. Reactions usually ... frequent adverse reactions to
drugs. Every physician will see patients suffering from them. Most are benign, but
a few can be life-threatening. Prompt recognition of severe reactions, drug
withdrawal,...
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Chapter 056. Cutaneous Drug Reactions (Part 2) pps
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07/07/2014, 01:20
... frequent in CD4+ clones while CD8+
Chapter 056. Cutaneous
Drug Reactions
(Part 2)
PATHOGENESIS OF DRUG REACTIONS
Untoward cutaneous responses to drugs can arise as a result of
immunologic ... preventive
measures.
Immunologic Drug Reactions
For most acute drug eruptions, benign or severe, accumulated data suggest
an immunologic basis. In the last 10 years drug- specific T cell clones were ... the most frequent causes of IgE-
dependent reactions to drugs, which require prior sensitization. Release of
mediators is triggered when polyvalent drug protein conjugates cross-link IgE
molecules...
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Chapter 056. Cutaneous Drug Reactions (Part 3) docx
Ngày tải lên :
07/07/2014, 01:20
... PRESENTATION OF CUTANEOUS DRUG
REACTIONS
Nonimmune Cutaneous Reactions
EXACERBATION OR INDUCTION OF DERMATOLOGIC
DISEASES
stimulation of T cells by medications leads to reactions that are ... neutrophil-mediated drug
reaction.
One may therefore assume that the final pattern of drug eruptions results
both from the nature of effectors—cytotoxic T cells in blistering reactions,
chemokines in reactions ... and response.
GENETIC FACTORS AND CUTANEOUS DRUG REACTIONS
Specific genetically determined defects in the ability of an individual to
detoxify toxic reactive drug metabolites predispose such...
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Chapter 056. Cutaneous Drug Reactions (Part 3) pps
Ngày tải lên :
07/07/2014, 01:20
... in patients receiving cytotoxic
drugs can be increased by exposure to sunlight.
Chapter 056. Cutaneous
Drug Reactions
(Part 3)
PIGMENTATION CHANGES
Drugs, either systemic or topical, ...
Development of the syndrome is unrelated to drug dose, and the course is
not altered by discontinuation of the drug after onset of the eruption. Warfarin
reactions are associated with protein C ... DRUG- INDUCED HAIR DISORDERS
Drug- Induced Hair Loss
Medications may affect hair follicles at two different phases of their cycle.
Anagen effluvium occurs within days of drug administration,...
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Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) pdf
Ngày tải lên :
25/03/2014, 05:20
... 1báo
cáo về bệnh thận nhiễm độc.
(theo Reactions Weekly; Số
1018;
11/9/2004)
TCNCYH 36 (3) - 2005
91
Phản ứng có hại của thuốc
(Adverse Drug Reactions; ADR)
G.S. Hoàng Tích Huyền
Bộ...
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Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf
Ngày tải lên :
18/02/2014, 08:20
... of pyruvate, the various
biochemical reactions involving pyruvate are the
most intensely studied and are well understood.
Thus, they serve as prototypical reactions for the
enzymic oxidative conversion ... MINIREVIEW
Reaction mechanisms of thiamin diphosphate enzymes:
redox reactions
Kai Tittmann
Albrecht-von-Haller-Institut fu
¨
r Pflanzenwissenschaften und Go
¨
ttinger ... February 2009)
doi:10.1111/j.1742-4658.2009.06966.x
Amongst a wide variety of different biochemical reactions in cellular car-
bon metabolism, thiamin diphosphate-dependent enzymes catalyze the oxi-
dative...
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R INTE S OF MEDIC REPORTING ADVERSE DRUG REACTIONS DEFINITIONS OF TERMS AND CRITERIA FOR THEIR USE ppt
Ngày tải lên :
07/03/2014, 10:20
... of skin lesions and
therefore encompassing virtually all cutaneous adverse reactions.
As a general rule, in reporting cutaneous drug reactions specific terms
should be used, but only when the ... of the skin. Photosensitivity reactions may be pleomorphic and
include dermatitis-like reactions.
Phototoxic reactions, which are non-immunological events caused by
drugs or chemicals, are far ... for
Reporting Adverse Drug Reactions 9
Skin and Appendages Disorders (SOC 0100) 9
Introduction 9
Terms 10
Dermatitis (Eczema) 10
Dermatitis exfoliative 10
Fixed drug eruption. 11
Lichenoid drug eruption...
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Plant physiology - Chapter 8 Photosynthesis: Carbon Reactions pdf
Ngày tải lên :
07/03/2014, 20:20
... Chapter 8
Light
Light reactions
Chlorophyll
Carbon reactions
Triose
phosphates
O
2
H
2
O
CO
2
+
H
2
O
(CH
2
O)
n
NADP
+
ADP
P
i
NADPH
ATP
+
+
FIGURE 8.1 The light and carbon reactions of photosynthe-
sis. ... chloroplasts.
These stroma reactions were long thought to be independent of light
and, as a consequence, were referred to as the dark reactions. However,
because these stroma-localized reactions depend ... oxidative
reactions. The flow of carbon, nitrogen and oxygen are indi-
cated in black, red and blue, respectively. See Table 8.2 for a
description of each numbered reaction.
Photosynthesis: Carbon Reactions...
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Women and Adverse Drug Reactions Reporting in the Canadian Context pot
Ngày tải lên :
22/03/2014, 11:20
... voluntary reporting of adverse drug reactions was
inadequate, the jury’s key recommendation called for a national system for the mandatory
reporting of adverse drug reactions. Mandatory reporting, ... adverse drug
reactions. But as , Dr Joel Lexchin - a Toronto physician who has extensively researched the
drug industry - has said, Canada’s regulatory system is “good at not letting drugs on ...
adverse drug reactions in
Canada, using a 1:10 ratio of the population
of Canada to that of the
US, would total 7,600 annually – 10% of the estimated 76,000 deaths due to adverse drug
reactions...
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Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) docx
Ngày tải lên :
03/04/2014, 00:20
... TCNCYH 29 (3) - 2004
Phản ứng có hại của thuốc
(Adverse Drug Reactions; ADR)
GS.TSKH. Hoàng Tích Huyền*
1. Gatifloxacin và chuyển hoá bất
thờng của ... cảm, lú lẫn, thao
thức khi đó phải ngừng ngay mefloquin và
báo cáo với thầy thuốc".
(Theo Reactions Weekly, 01/11/2003, số 975).
4. Doxycyclin gây viêm loét thực quản
(Australia, Tân Tây...
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báo cáo hóa học:" Confronting TB/HIV in the era of increasing anti-TB drug resistance" pdf
Ngày tải lên :
20/06/2014, 08:20
... Anti-Tuberculosis Drug Resistance in the world Report No
4. The WHO/IUATLD Global project on anti-tuberculosis drug resistance
surveillance . WHO/HTM/TB/2008.394
35. Koenig R: Drug- resistant tuberculosis. ... effect of anti-tuberculous drugs
on liver function. J Postgrad Med 2006, 52:92-6.
30. MMWR:
55:11. 2006, March 24
31. Gandhi NR, Moll A, Sturm AW, et al.: Extensively drug- resistant
tuberculosis ... Infec-
tion and Multi drug resistant tuberculosis – the perfect
storm. Journal of Infectious Diseases 2007, 196:S86-107.
33. Dubrovina I, Miskinis K, Lyepshina S, et al.: Drug resistant tubercu-
losis...
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Báo cáo hóa học: " Self-Assembled Polymeric Micellar Nanoparticles as Nanocarriers for Poorly Soluble Anticancer Drug Ethaselen" pdf
Ngày tải lên :
22/06/2014, 00:20
... chain length. In
addition, similar to drug- loaded micelles reported earlier
[15, 27], the size of drug- loaded micelles was about 10 nm
bigger than that of drug- free micelles, suggesting that
ethaselen ... influence the pharmacokinetics of drugs [39, 40],
while much more drug would be accumulated in the solid
tumor region due to delay of the circulation time of drugs for
polymeric micelles [22, ... loss, resulting from the toxic effect of the drug,
indicating that this micelle-based drug delivery system
could reduce unwanted side effects of anticancer drugs
during cancer therapy.
Overall, ethaselen-loaded...
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