challenges and an agenda for action

... soil, and water has deteriorated Humans, animals, and plants have been affected Toxic pollutants cause many kinds of illnesses in humans and animals Oxides of nitrogen and sulfur, the ozone, and ... plants, and animals adapted to lack of water Desertification: Formation of deserts in arid and semi - arid regions due to change in climate and overgrazing Detritus: Any organic waste from plants and ... the loss of virgin forests and soil fertility, soil erosion of deserts These in turn deprive many animals and plants of their natural habitat Extinction of many animal and plant species is a direct...

Ngày tải lên: 03/10/2013, 09:20

... the time.' In many points, Roman feeling for Nature was more developed than Greek For instance, the Romans appreciated landscape as a whole, and distance, light and shade in wood and water, reflections, ... the Creator stars and seasons, hail-storm and lightning, earth, sea, river and spring, cloud and night, plants, animals, and light; and he describes the flood in bold flights of fancy In the three ... beauty and plastic force there is in Homer's comparisons and in his descriptions of times and seasons! what a clear eye and warm heart he has for Nature in all her moods! and what raw and scanty...

Ngày tải lên: 21/02/2014, 20:20

... venture of the Erste Group and Erste Foundation and one of the main financial investors in Central and Eastern Europe Their vision is that all individuals and firms in Central and Eastern Europe have ... ESBG Managing Director, delivered the closing speech, stating that microfinance is a savings bank tradition and an important means to stimulate social inclusion and job creation Savings banks ... microenterprises, and that provide microfinance-specific training for both savings banks and business support entity employees Another key aspect highlighted was the need to promote quality standards for microfinance...

Ngày tải lên: 06/03/2014, 10:20

... Age-specific death rates for England and Wales, and London from Wrigley et al (1997, Table 6.14) and Landers (1992, Table 3), respectively To compute the rates of England and Wales (without London), ... death rates for London and England and Wales excluding London As the table shows, mortality rates in London were more than double the mortality rates in England and Wales Szreter and Mooney (1998) ... observed changes in life expectancy and age-specific death rates Before 1750, infant and child mortalities were very high and had a considerable impact on life expectancy at birth and overall...

Ngày tải lên: 17/03/2014, 08:20

... Governance and Urban Development 31 5.1 Governance and Politics in China 31 5.2 Environmental Governance 33 5.3 Local Urban Governance 34 5.4 Governance and Urban Sustainability 36 5.5 An Emerging ... spaces and places of labor, life and leisure, there is the potential for new social and spatial forms and relations to develop (1997) He points to the possibilities of transforming urban landscapes ... due to urban development and recent changes in the urban landscape This background facilitates in the understanding of ideas, decisions and actions made pertaining to urban development and its...

Ngày tải lên: 19/03/2014, 11:20

Ngày tải lên: 01/04/2014, 09:21

Ngày tải lên: 01/04/2014, 09:21

... Ellie Bru, Anne Goebel, Vanessa Evans, and Chris Cleveland On the IBM side, Steven Stansel and Ellice Uffer worked tirelessly on getting the message out there for the Mastering XPages book and are ... variables, objects, and even Managed Beans are forcefully refreshed as a consequence of any application design changes Request-scoped variables, objects, and Managed Beans, on the other hand, automatically ... my parents and family: I love you all and hope you enjoy reading another great book about XPages! For “my two girls,” Paula and Anna-Rose: a beautiful wife and special daughter who mean absolutely...

Ngày tải lên: 31/05/2014, 00:46

... for understanding postsocialist change, and processes of differentiation in particular By comparing the life stories and organizational histories of women such as Ivana, Svetlana, and Vira, and ... organizing simultaneously engendered changes in women activists’ profession, expertise, and interests, and sparked personal transformations Among my informants Ivana was unique in that her husband ... organizations whose leaders and members “just ask for handouts.” Ivana clearly privileged a language of self-reliance and personal initiative Perhaps more than any other activist I knew, Ivana’s...

Ngày tải lên: 04/06/2014, 17:40

... expressing and DAG pavement cells, 16 had anticlinal microtubules and/ or microtubule bundles within one or more lobes Therefore anticlinal microtubules are common features of expanding lobes, and models ... objective was used for and DAG fields, and a 20X 0.5 NA objective was used for 12 and 18 DAG cells Intact GFP-TUB6- Additional file 1: Example images and plots of the cell boundary segment analysis from ... the raw data for the population and time-lapse imaging and analyzed the population data DS carried out the GFP-TUB6 live cell imaging DS and CZ drafted the manuscript All authors read and approved...

Ngày tải lên: 11/08/2014, 11:21

... Esther Yeoh, Tan Yeling, Ong Yanchun, Melissa Ong, Jasmin Kaur and Sandra Ng have been outstanding in their unswerving patience, company and loyalty Ong Yanchun deserves special thanks Acknowledgements ... neoliberalism and the World Bank were forced, both by pressure from within and without, to change And change they did New emphases were placed upon the importance of institutions and qualities ... important information, both on the project itself and on the Bank’s work more generally Many interviewees were identified and contacted (both inside and outside of the Bank) leading up to and throughout...

Ngày tải lên: 03/11/2014, 12:59

... livelihood and market linkages, natural resource management, cultural diversity, education and health care, climate change and environment, and poverty analysis and evaluation Poster and video ... for people living in those areas and is a challenge for natural resources Particularly, land and forests are being overexploited and overused, affecting to the sustainability [Sushil Pandey and ... issues and challenges, focused on the impact of livelihood and market linkages, natural resource management, climate change, health and education, cultural diversity, and poverty analysis and evaluation;...

Ngày tải lên: 11/08/2015, 09:36

... McShane’s identity she obtained 3.2 Basmajian’s Identity and Bridgeman’s Identity In this section, we review Basmajian’s identity and Bridgeman’s identity 3.2 Basmajian’s Identity and Bridgeman’s ... transformations are called hyperbolic transformations if λ are real and strictly loxodromic transformations if λ are not real A M¨bius transformation is parabolic if it is conjugate to the transformation ... the Poincar´’s models, and identified the e group of isometries to fractional linear transformations, i.e M¨bius transformations o 2.2 M¨bius transformations o M¨bius transformations play a central...

Ngày tải lên: 10/09/2015, 09:09

... mixed and left to stand at room temperature for 5-10 minutes The organic and aqueous phases were separated by adding 240μl of chloroform and 240 μl of 2N KCl The mixture was then vortexed, and ... concentrations tested (10μM, 25μM, 50μM, 75μM, and 100μM), none of the six compounds inhibited DAGK and human PKC alpha (Figure 2.8 and Figure 2.10) On the other hand, and in agreement with previous findings ... can be clearly seen that the transfection was very successful and the over-expression was shown to yield a substantial increase in SPHK activity, 18-fold for SPHK1 and 5-fold for SPHK2, in transfected...

Ngày tải lên: 11/09/2015, 16:06

... significant 3.2 RESULTS 3.2.1 RNA Expression of SPHK1 and SPHK2 in Human BM- and ADMSCs Human BM-MSCs and AD-MSCs were tested on their mRNA expression of SPHK1 and SPHK2 using real time PCR, and ... prepared and added into each reaction tube Reactions were incubated at 37°C for 60 minutes, and heated at 95°C for minutes to deactivate the reverse transcriptase This is the ‘second-strand reaction’ ... Human MSCs Growth 3.2.2.1 Effects of Different Dosages of DMS and CP6 on Human BM- and AD- MSCs Growth CP6 and DMS were first tested at different concentrations for their potential cytotoxic and/ or...

Ngày tải lên: 11/09/2015, 16:06

... in human BM- and AD- MSCs proliferation Figure 4.6 Function of S1P and serum in human BM- and AD- MSCs proliferation Human BM -and AD- MSCs were cultured in different conditions for days, and cell ... expression in human BM- and AD- MSCs Table B and C represent data from two donors cells of AD-MSCs Mouse IgG1 and IgG2a were used as the isotype controls and five thousand events per antibody group ... (P42/44) activation and iκBα phosphorylation in human BM- and AD- MSCs Cells were harvested in serum-free DMEM for half an hour (ctrl) and treated with 1μM S1P for 5min, 10min, 30min, and 60min P44/42...

Ngày tải lên: 11/09/2015, 16:06

... affected the osteogenic differentiation and adipogenic differentiation in human MSCs differently In human BM- and AD- MSCs osteogenic differentiation, 0.5μM CP6 and DMS showed to promote the osteogenic ... human MSCs osteogenic and adipogenic differentiation switching To our knowledge, this is the first report on inhibitors of SPHK mediating human BMand AD- MSCs differentiation into osteogenic and ... accumulated on cell expansion and differentiation might also be applicable in other types of stem cells Also, it should be noticed that both human BMand AD- MSCs are primary cells, and thus they may...

Ngày tải lên: 11/09/2015, 16:06

... (1997) "Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan." Hum Mol Genet 6(8): 1349-56 Nirmalanandhan, V S., M Rao, ... E., L De Angelis, et al (2004) "Isolation and expansion of adult cardiac stem cells from human and murine heart." Circ Res 95(9): 911-21 Mets, T and G Verdonk (1981) "In vitro aging of human bone ... Khovidhunkit, Weerapan, MinSun Kim, et al (2004) “Effects of Infection and Inflammation on Lipid and Lipoprotein Metabolism: Mechanisms and Consequences to the Host” J Lipid Res 45(7):1169-96 Kilian, O.,...

Ngày tải lên: 11/09/2015, 16:06

... proliferation and differentiation 1.3 SPHK AND S1P REGULATION IN STEM CELL RESEARCH As was mentioned above, S1P can act as an intracellular second messenger and as an extracellular ligand for specific ... Objectives and significance The significance for the need to study the potential applications and significance of using SPHK and S1P in stem cells research, derived from the current understanding ... human adult stem cell proliferation and stemness maintenance, and how SPHK inhibition would affect human adult stem cell proliferation and differentiation More details about the research goals and...

Ngày tải lên: 11/09/2015, 16:06