case 1 mr l

... Pathol 19 91, 16 5 :18 7-2 01 Page of (page number not for citation purposes) Theoretical Biology and Medical Modelling 2006, 3:5 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Evan GI, Wyllie AH, Gilbert ... 2005, 435 :12 67 -12 70 Huntly BJP, Gilliland DG: Summing up cancer stem cells Nature 2005, 435 :11 69 -11 70 Holtz MS, Slovak ML, Zhang F, Sawyers CL, Forman SJ, Bhatia R: Imatinib mesylate(STI5 71) inhibits ... Gustav; 19 14 Marley SB, Lewis JL, Gordon MY: Progenitor cells divide symmetrically to generate new colony-forming cells and clonal heterogeneity Br J of Haematol 2003, 12 1:643-648 Deininger MW, Goldman...

Ngày tải lên: 13/08/2014, 23:20

... proactively looked for mechanisms of PI resistance in the CAPAN -1 (BRCA2 null) cell line by treating the cells with the drug and identifying the genetic alterations in resistant clones Fascinatingly, ... through an alternative pathway, in this case base excision repair This combination results in the cells sustaining fatal genomic instability In elegant work that has recently been published, Ashworth’s ... BRCA2-deficient tumours This class of compounds was identified through a synthetic lethality screen, in which the cell, already sensitized to DNA damage by loss of BRCA1/2, is overwhelmed by the combination...

Ngày tải lên: 14/08/2014, 08:21

... therapy is both 10 7 10 8 Sweden Sweden China USA Li et al (19 99) Li et al (19 99) Chan et al (20 01) Miller et al (2002) Early-stage ovarian Cervical Cervical Cases: 51 Controls: 50 healthy Cases: 37 ... quality of life Cancer 11 2(3), 616 –625 (2008) Ferrell B, Smith SL, Cullinane CA, Melancon C Psychological well being and quality of life in ovarian cancer survivors Cancer 98(5), 10 61 10 71 (2003) ... 38 Oleson M Subjectively Perceived Quality of Life IMAGE J Nurs Scholarsh 22(3), 18 7 19 0 (19 90) 40 Guyatt G Postscript Controlled Clinical Trials 12 , 266S–269S (19 91) 41 WHOQOL group The World...

Ngày tải lên: 05/03/2014, 15:20

... pharmaceuticals is mainly by lower to mid-level health workers (Figure 1) Guidelines for the supply management of HIV/AIDS existed in all the countries but were not always available at treatment ... [http://www.pepfar.gov/documents/organization /11 5 411 .pdf] Health Systems Management: Pharmaceuticals The World Bank [http://siteresources.worldbank.org/HEALTHNUTRITIONAND POPULATION/Resources/2 816 27 -10 9569 814 016 7/GovindarajWBPharmacuetical-whole.pdf] ... of essential drugs in sub-Saharan Africa: some issues and possible solutions Social Science Medicine 19 91, 32 (11 ) :12 01- 18 Ford N, Wilson D, Costa Chaves G, Lotrowska M, Kijtiwatchakul K: Sustaining...

Ngày tải lên: 18/06/2014, 17:20

... 0 01 000000000000 · · · 010 000000000000 · · · 011 ··· 11 111 111 111 11 · · · 10 11 111 111 111 11 · · · 11 212 8 = 3.4 × 10 38 11 11 · · · 0000 11 00 · · · 11 00 10 01 · · · 10 01 ··· 10 10 · · · 10 10 ∼ 212 4 ... 006276 Number of repeats 2 2 2 2 2 2 2 2 2 2 2 2 Length 13 10 10 10 12 10 11 11 10 10 10 13 12 11 11 11 11 11 11 10 10 10 10 11 Phrase tttctcttttcct tcagggaggg ccccccagct gcagaggcag ttttatttataa cagtttcctt ... 2302 15 45, 2447 2 014 , 2776 2 812 , 3759 10 35, 14 08 525, 15 91 1464, 18 28 215 9, 2267 10 10, 10 91 160 14 0 3’UTR 12 0 10 0 80 OSCR phrase OSCR phrase 60 40 20 OSCR sequence hsa-miR- 218 rno-miR- 218 xtr-miR- 218 ...

Ngày tải lên: 22/06/2014, 19:20

... trial of low-dose gemcitabine in prolonged infusion and cisplatin for advanced non-small cell lung cancer Anticancer Drugs 2005, 16 :11 29 -11 34 Lassarat S, Jootar S: Ongoing challenges of a global ... large scale feasibility in quality control, we suggest working at the small scale level to test random samples or pilot settings upon invitation from the local authorities in some developing countries ... incidence, and multiple available, effective treatment options provides an excellent starting point for developing economically sustainable cancer control strategies that could be tailored in LMCs for...

Ngày tải lên: 09/08/2014, 04:21

... and MRI pituitary fossa were all normal She was noted to have an elevated IgG at 21. 6 and a raised SMA titre (IgG class >800) Type diabetes mellitus was confirmed with an oral glucose tolerance ... http://www.wjso.com/content/6 /1/ 132 reduction in the size of the lymph nodes CK was still elevated at 453 but IgG was improved at 18 .1 At months of treatment with anastrozole, the CK has started to fall (figure 1) Symptomatically ... months later her mobility had continued to decline and the impaired pin-prick sensation was now to the level of the upper tibiae She had developed palpable lymph nodes in her supraclavicular fossa...

Ngày tải lên: 09/08/2014, 07:22

... 2 .14 1. 38 -2.20 3. 31 8 .10 1. 12 7.62 1. 97 0 .15 2.36 -4.58 4.88 6.97 2.04 6.93 28 0.00 1. 85 -3.69 3.69 7.07 2.07 25 0.08 1. 55 -3.02 3 .18 7 .19 28 0 .11 2.33 -4.55 4.77 28 0.32 1. 70 -3.08 28 0.54 1. 82 ... -4. 31 5.05 6.96 2 .17 6.48 2 .18 0.4 0.000 27 0.33 1. 27 -2. 21 2.88 8.50 0.96 8.00 1. 34 0 .17 7 27 0.04 2.53 -5.03 5 .11 7.64 2.44 7.24 2.47 27 0. 81 1.88 -2.95 4.58 8. 21 1.60 7.07 2.55 0 .1 0.3 91 0.4 ... 0.58 1. 42 -2.26 3.42 8.43 0.96 7.75 1. 65 0. 014 28 -0.07 2.80 -5.67 5.53 5. 31 3.66 5. 31 3 .12 0.3 0.6 27 0.78 2.82 -4.86 6.42 7 .11 2.22 6.24 2.44 0.078 27 0.37 1. 86 -3.36 4 .10 7.68 1. 91 7 .17 2 .11 ...

Ngày tải lên: 09/08/2014, 10:21

... Boyle GM: Long-term survival in metastatic transitionalcell carcinoma and prognostic factors predicting outcome of therapy J Clin Oncol 19 99, 17 : 317 3- 318 1 Bellmunt J, Albanell J, Paz-Ares L, Climent ... trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer J Clin Oncol 2000, 18 :13 6 -14 7 16 Rothenberg ML, Oza AM, Bigelow RH, ... Bellmunt J: Gemcitabine and oxaliplatin combination: a multicenter phase II trial in unfit patients with locally advanced or metastatic urothelial cancer Annals of Oncology 2007, 18 :13 59 -13 62 11 ...

Ngày tải lên: 10/08/2014, 22:20

... serum removal Mol Biol Cell 2000, 11 :11 03 -11 12 Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, Kaiser RA, Lorenz JN, Voisin L, Saba-El-Leil MK, Meloche S, Pouyssegur J, et al: MEK1-ERK2 signaling pathway ... 3T3 -L1 cells J Biol Chem 19 88, 263 :12 7 21- 12727 Raman M, Chen W, Cobb MH: Differential regulation and properties of MAPKs Oncogene 2007, 26: 310 0- 311 2 Yoon S, Seger R: The extracellular signal-regulated ... kinase (MEK)-MAPK cell survival signals Cell Growth Differ 20 01, 12 :397-408 Balmanno K, Cook SJ: Tumour cell survival signalling by the ERK1/2 pathway Cell Death Differ 2009, 16 :368-377 Xia Z,...

Ngày tải lên: 10/08/2014, 22:20

... gel filtration Gel filtration of extracellular polymer Gel filtration of the extracellular polymer was performed through a column (26×300 mm) of Bio-Gel P -10 0 previously equilibrated with 10 ... extracellular polymers Table Flocculating activity of extracellular activated sludge Flocculating activity Suspended solids Cations － Kaolin clay ＋ Activated charcoal ＋ Muddy water － Silicic acid ... extracellular polymer extracted from activated sludge Extent of flocculation (%) pH Kaolin clay Activated charcoal Control With polymer Control With polymer 2.5 12 .4 79.6 19 .6 67 .1 3.2 0.8 26 .1 20.5...

Ngày tải lên: 05/09/2013, 09:08

... in classroom methodology Silence is a cultural value that is relative to Western and Japanese cultures Humor, teasing and silence are also highly diverse culturally so the teacher must be self-aware ... After 10 minutes, learners close their books and can volunteer to perform the memorized dialogue With books still closed, the teacher plays the same dialogue from the tape again allowing learners ... attendance, but that they will be allowed to make up tests and quizzes By explicitly stressing this kind of seemingly trivial information, the teacher can save a lot of valuable class time and create...

Ngày tải lên: 06/09/2013, 10:10

... (wal-) are valence, valiant, valid, value, avail, and convalesce ● “This leads to a tendency for realized earnings to fall below the level that would validate or re-valorize the capitalized values ... South Africa) mellifluous (muh-LIF-LOO-uhs) adjective Smoothly or sweetly flowing, as like honey From Middle English, from Late Latin mellifluus, from melli-, from Latin mel (honey) + fluere (to flow) ... in Silicon Valley raises capital and an industrious farmer in an African hamlet raises cattle, they are doing something very similar, etymologically speaking The words cattle and capital (also...

Ngày tải lên: 25/10/2013, 16:20

... many sellers oligopsony: a few buyers, many sellers monopoly: one seller, many buyers duopoly: two sellers, many buyers oligopoly: a few sellers, many buyers Sonic Boom Sonypoly: a Japanese electronics ... supplies, provisions, etc., of a specific type From Middle English chandeler, from Middle French chandelier, from Old French, from chandelle (candle), from Latin candela, We call them dumb animals, ... similar sounding words between English and Italian, when their meanings are completely divergent My wife rolls her eyes every time I jokingly call my barbecue the grillo—which means not grill,...

Ngày tải lên: 25/10/2013, 16:20

... over 10 00 examples 4 .1. 1 Grammatical Features of WIRHs in English collected from different data 4 .1. 1 .1 Grammatical Features of WRHs in English 3.2.2 Data Analysis a, Specific grammatical features ... compared be carefully read and that examples should be cautiously selected to 2.2.3.4 Collocation ensure a satisfying reliability of the results It is required that the Collocation is a systematic ... collocate with nouns, noun phrase, or adj vocabulary And we can see that teaching/learning vocabulary by English is an inflecting language, therefore, its faculty of family tree or lexical field...

Ngày tải lên: 26/11/2013, 13:31

... translation of complex compound words or complex phrases Similarly, following examples will illustrate what I mention: English Vietnamese equivalence Compliance with Investment law Tuân thủ luật ... structure of the SL will be preserved as closely as possible, but not so closely that the TL structure will be seriously distorted” _McGuire (19 80: 2)_ Some scholars defined translation as an art ... translation all over the world Following is some typical definitions : The first definition is “Translation is the replacement of textual material in one language by equivalent textual material...

Ngày tải lên: 11/12/2013, 23:51

... English terms 15 2 .1 Systematic 15 2 .1 Internationalism 16 2.2 Nationalism 16 2.3 Popularity .17 Popular terms relating to Water Ssector 17 3 .1 ... sustainable development, human health, and life has not always been fully appreciated Therefore, Water sector still faces substantial challenges highlighting the urgency for the Government to complete ... usability and cognitive psychology Traditionally in translation circles, researchers have only been interested in terminology but unless you‘re actually a terminologist, to reduce technical translation...

Ngày tải lên: 11/12/2013, 23:55

... … 2 .1 The methods closest to the source language 10 2 .1. 1 Word – for – word translation 10 2 .1. 2 Literal translation 10 2 .1. 3 Faithful translation 11 2 .1. 4 ... Communicative translation 12 Strategies for translation 13 3 .1 With non – equivalence at lexical level 13 3 .1. 1 Translating by a more specific word 13 3 .1. 2 Translating ... general word 13 3 .1. 3 Translating by cultural substitution 13 3 .1. 4 Translating by using a loan word plus explanation 14 3 .1. 5 Translating by using a paraphrase 14 3 .1. 6...

Ngày tải lên: 11/12/2013, 23:55

... (home) at (the petrol 71 12 31 10 13 48 88.75% 15 % 38.75% 12 .5% 16 .25% 60% 68 49 70 67 32 11 .25% 85% 61. 25% 87.5% 83.75% 40% 14 ) station) in (his hand) 41 51. 25% 39 48.75% 41 15) 16 ) at (university) ... reflect the general characteristics of rule learning such as faulty generalization, incomplete application 13 of rules and failure to learn conditions under which rules apply Developmental errors ... either global or local Global errors violate the comprehension of the overall structure of a sentence as in the following instance: * The policeman was in this corner whistle … (Ellis 19 97:20)...

Ngày tải lên: 18/12/2013, 10:04