... the different in vitro models of HCV that have been developed and their contribution to our current knowledge of the virus life cycle Around 10 years after discovery of the HCV genome and after ... lines of human or nonhuman origin [61–63] One may speculate that the broad tropism of these HCVpp might be influenced by the background infectivity of VSV Moreover, some of these viruses harboured ... efficiencies In the field of HCV replication, a large breakthrough was the development of subgenomic replicons that allowed examination of the viral components of FEBS Journal 274 (2007) 4705–4718...
Ngày tải lên: 16/03/2014, 05:20
... paralogous chromosomes also supports our hypothesis In conclusion, the analysis of amphioxus enzymes contributes to improving our understanding of the functional complexity of vertebrate gene families ... specific activity of each amphioxus enzyme was 0.25 nmol of retinolÆmin)1Æ(mg of microsomes))1 for RDH1 incubated with 15 lm all-trans-retinal, and 1.4 nmol of retinolÆmin)1Æ(mg of microsomes))1 ... addition of cofactor and carried out for 15 at 37 °C in 0.5 mL The amount of protein used in the reaction mixture was 15 lg The reaction was terminated by the addition of an equal volume of cold...
Ngày tải lên: 07/03/2014, 09:20
Báo cáo khoa học: Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues ppt
... membrane) the sign of the distance change was the same as that observed in the three structural states of Chang, and the magnitudes of distance changes for three of the four pairs of residues for ... mechanics of translocation for which FEBS Journal 277 (2010) 550–563 ª 2009 The Authors Journal compilation ª 2009 FEBS 557 The structure of eukaryotic ABC multidrug pumps I D Kerr et al of the ... domain swapping of the ICL helices for ABC exporters An increasing number of recent studies of naturally occurring or artificially swapped domains has widened the range of functions of domain swapping...
Ngày tải lên: 22/03/2014, 21:20
Báo cáo y học: "Recent advances in our understanding of human host responses to tuberculosis" doc
... in the field of mycobacterial genetics Such advances in our understanding of the basic biology of M tuberculosis should aid in the design and evaluation of new therapeutic drugs Understanding ... conduct of direct experiments using human tissues, as well as in vivo studies of human immune responses to tuberculosis, represents a major advance in our understanding of the pathogenesis of this ... and dendritic cells, which are of course professional antigen-presenting cells commentary the involvement of some key cytokines and antigens [45] In a murine model of leishmaniasis, it appears...
Ngày tải lên: 12/08/2014, 18:20
Our understanding of global geology during the 20th century(notes 6)
... 0.3% of the total radius of the earth This is roughly equivalent to the thinnest layer of skin on the outside of an onion The mantle has a total thickness of 2885 km and comprises more than 80% of ... comprises only one-sixth of the volume of the earth, it represents almost one-third of its mass It is predominantly made up of metallic iron along with some nickel and smaller amounts of sulphur and oxygen ... filled with thousands of metres of sediments Following development of acoustic depth sounders in the 1920s [Figure 11.12] the number of depth readings increased by many orders of magnitude, and by...
Ngày tải lên: 01/12/2015, 23:14
Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... Eiser C, Morse R: A review of measures of quality of life for children with chronic illness Arch Dis Child 2001, 84:205-211 Connolly MA, Johnson JA: Measuring quality of life in pediatric patients ... much does your child resist taking medication at school? References • How often does your child's dose at school get missed or forgotten? • How often has your child had problems because of a missed ... your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Determinants of improvement in quality of life of alcohol-dependent patients during an inpatient withdrawal programme"
... index (26) Quality of life of patients on admission and at discharge Fifty-four patients (13%) left our centre prematurely before the end of the inpatient programme thus their end of treatment ... Predictive factors of quality of life on admission Two-thirds of patients had a Physical Component Summary score of >42 and two-thirds of patients had a Mental Component Summary score of >25 The factors ... consumption patterns, and health-related quality of life of primary care patients Alcohol Clin Exp Res 1997; 21:899-905 Welsh JA, Buchsbaum DG, Kaplan CB Quality of life of alcoholics and non-alcoholics:...
Ngày tải lên: 03/11/2012, 10:52
Báo cáo y học: "Sustained High Quality of Life in a 5-Year Long Term Follow-up after Successful Ablation for Supra-Ventricular Tachycardia. Results from a large Retrospective Patient Cohort"
... scores Irrespective of the well known shortcomings of the Symptom checklist because of the nonspecific nature of a number of the symptoms asked for and the lack of assessment of functional status ... Bubien RS, Knotts-Dolson SM, Plumb VJ, Kay GN Effect of Radiofrequency catheter ablation on health-related quality of life and activities of daily living in patients with recurrent arrhythmias ... F, Saoudi N, Poty H, Douillet R, Cribier A Radiofrequency catheter ablation of common atrial flutter: Significance of palpitations and quality -of- life Evaluation in patients with proven isthmus...
Ngày tải lên: 03/11/2012, 11:44
Understanding of Our Business
... interventions to improve results based on analysis of the business • Able to evaluate the cause and effect of our interventions and anticipatively offer counter measures to improve results • Takes ... to lead discussions about the business Advanced • Solid understanding of the business, the key consumers and the positioning and "state" of the competitive set • Called upon to make suggestions ... strategy to improve results • Capable of leading the BULT in the analysis of results and guiding them to clear, focused action plans • Used as the Master developer of those training to lead the HR...
Ngày tải lên: 19/10/2013, 07:15
Understanding of Our Business
... interventions to improve results based on analysis of the business • Able to evaluate the cause and effect of our interventions and anticipatively offer counter measures to improve results • Takes ... Advanced • Solid understanding of the business, the key consumers and the positioning and "state" of the competitive set • Called upon to make suggestions ... strategy to improve results • Capable of leading the BULT in the analysis of results and guiding them to clear, focused action plans • Used as the Master developer of those training to lead the HR...
Ngày tải lên: 19/12/2013, 11:02
Tài liệu Improving Campus Quality of Life with In-Building Wireless pdf
... a coffeehouse, stores, and a post office), and a new extension (opened in 2005) of the 122,000 square foot Bostock library Both of these projects are scheduled for completion in the spring of ... unevenness in the quality of life. ” Other future plans include the integration of 800 MHz public safety and paging traffic into the same Unison network, as well as the addition of EV-DO data services ... current and future mobile services that add to the quality of life, part of the ongoing drive for improvements that keep it in the top 10 ranking of American universities Website: www.adc.com From...
Ngày tải lên: 21/12/2013, 07:17
Tài liệu Psychometric properties of the quality of life scale Child Health and Illness Profile-Child Edition in a combined analysis of five atomoxetine trials pdf
... all four SS items, but also from two items from the SH sub-domain (item 1: ‘‘How often does your child have a lot of fun?’’ and item 4: ‘‘How often does your child feel happy?’’) The items of the ... items 31 (‘‘How often did your child have trouble walking one block?’’), 32 (‘‘How often did your child have trouble walking up one flight of stairs?’’), and 33 (‘‘How often did your child have ... Items 44 (‘‘How often did your child play active games or sports?’’), 45 (‘‘How often did your child play hard enough to start sweating and breathing hard?’’), and 46 (‘‘How often did your child run...
Ngày tải lên: 12/02/2014, 19:20
Tài liệu Chronic Disease, Functional Status and Quality Of Life Among The Elderly In Singapore pdf
... mostly for reported poor quality of life In the face of impaired physical and mental functioning, perceived social handicap stands in the way of realizing quality of life Success in improving ... quality of life “The process of optimizing opportunities for physical, social and mental well-being throughout the life course in order to extend healthy life expectancy.'' (Ministry of Health, ... et al, Journal of Epidemiology and Community Health, 2003; 57,1: 17-22 Addresses the problem at its source Effective programme of mass education to modify harmful lifestyles and behaviour and...
Ngày tải lên: 14/02/2014, 06:20
Tài liệu National Development Plan 2007-2013: TRANSFORMING IRELAND A Better Quality of Life for All docx
... priorities needed to realise the vision of a better quality of life for all This better quality of life will be achieved by supporting the continued development of a dynamic and internationalised ... out of 25; in terms of transport infrastructure, 27th out of 28; and in terms of efficiency of energy infrastructure, Ireland ranked 26th out of 28 Dublin ranked 28th out of 30 in terms of average ... generation of sufficient resources to ensure provision of comprehensive social and recreational facilities and services are all inherently bound together in the context of improving quality of life...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Reclaiming city streets for people Chaos or quality of life? ppt
... enjoy living there, and whether we want our children to grow up there One of the key issues affecting the quality of the environment and the quality of life in our towns and cities is road traffic ... European Commission Reclaiming city streets for people — Chaos or quality of life? Luxembourg: Office for Official Publications of the European Communities 2004 — 52 pp — 29.7 x 21 cm ISBN 92-894-3478-3 ... Economic appraisal of the health effects of air pollution, prepared by the ad-hoc group on the economic appraisal of the health effects of air pollution, 1999 (4) Source: Eurostat ( ) Source: European...
Ngày tải lên: 19/02/2014, 04:20
Factors related to quality of life in long-term survivors of gynecological cancer doc
... Treatment of Cancer – Quality of Life Questionnaire – Core Questionnaire; FACT-QoL: Functional Assessment of Cancer Therapy – Quality of Life; HRT: Hormone-replacement therapy; QLI: Quality of Life ... European Organization of Research and Treatment of Cancer – Quality of Life Questionnaire – Core Questionnaire; FACT-QoL: Functional Assessment of Cancer Therapy – Quality of Life; HRT: Hormone-replacement ... critical review of patient-rated quality of life studies of long-term survivors of cervical cancer Gynecol Oncol 102(3), 563–572 (2006) 13 Anderson B, Lutgendorf S Quality of life in gynaecologic...
Ngày tải lên: 05/03/2014, 15:20
Impact of chronic disease on quality of life among the elderly in the state of São Paulo, Brazil: a population-based study pptx
... and quality of life of elderly individuals (4, 5) The impact that disease has on quality of life should be assessed and monitored This can be achieved through surveys that include measurements of ... and other chronic medical conditions on health-related quality of life: is the whole greater than the sum of its parts? Health and quality of life outcomes 2005:3–12 24 Lebrão ML, Laurenti R Saúde, ... committees of the School of Medical Sciences of the State University of Campinas, Campinas, São Paulo RESULTS The data analyzed came from a total of 958 individuals—929 males and 029 females 60 years of...
Ngày tải lên: 05/03/2014, 21:20
Health related quality of life among the elderly: a population-based study using SF-36 survey pdf
... international data The aim of the present study was to provide a profile of SF-36 scales and analyze the influence of demographic and socioeconomic factors on health-related quality of life in an elderly ... had a per capita monthly income less than four times the minimum salary and 42.6% had less than four years of schooling (Table 1) Scores of quality of life were lowest in the following dimensions: ... Overview of the SF-36 Health Survey and International Quality of Life Assessment (IQOLA) project J Clin Epidemiol 1998; 51:903-12 10 Tsay SY, Chi LY, Lee CH, Chou P Health-related quality of life...
Ngày tải lên: 05/03/2014, 21:20
Health-related behavior and quality of life among the elderly: a population-based study pot
... income, work status, place of residence and number of chronic conditions component of quality of life, and smokers showed poorer quality of life than never-smokers The results of the present study ... reduces the risk of disease, increases life expectancy of those with illnesses and improves quality of life, though the harmful effects of smoking lasts for a certain amount of time depending ... Survey in the State of Sóo Paulo (ISA-SP), 20012002 in four areas of the state of Sóo Paulo, southeastern Brazil: the cities of Botucatu and Campinas; an area covering the cities of Itapecerica da...
Ngày tải lên: 05/03/2014, 21:20
THE URBAN AUDIT Towards the Benchmarking of Quality of Life in 58 European Cities docx
... consumption of energy is not per se a measure of the quality of life However, the good management of energy resources contributes to reductions in emissions, lower consumption of natural resources ... the points of supply, and differences in the standards applied Also the EU standards relate to several aspects of water quality, some of which are arguably more critical to quality of life than ... considered Of the four indicators discussed above, drinking water quality is perhaps the most pertinent to the quality of urban life There are however, differences in the way in which water quality...
Ngày tải lên: 06/03/2014, 23:20