blurring the lines between primary secondary and tertiary screening

... testing and mutation finding, including details of what the tests mean and how informative they are likely to be, and the likely timescale of being given the results • Information about the risks and ... familial breast cancer in primary, secondary and tertiary care’) gives details of the methods and the evidence used to develop the guidance (see section for details) The original full guideline is ... mother, father, daughter, son, sister, brother Second-degree relatives: grandparent, grandchild, aunt, uncle, niece and nephew; half sister and half brother Third-degree relatives: great grandparent,...

Ngày tải lên: 15/03/2014, 00:20

... in the northern region, Mchinji in the central region, and Balaka, Machinga, Zomba and Blantyre in the southern region The locations of interviews were based on the respondents’ preferences and ... policies and programmes to stem the epidemic, and their views of the consequences of high mortality due to AIDS for the future of their nation Thus, it was a practical venture to understand secondary ... HIV/AIDS by citing and explaining the dominant, international and “proper” responses The secondary and tertiary graduate Malawians also discussed these same topics in terms of what they perceive or...

Ngày tải lên: 20/06/2014, 08:20

... their performance when they send a referral letter, both on the compliance to the guidelines and the outcome for the patient Description of the measures Following the MRCs guidelines for complex interventions, ... on the theoretical and empirical background defined above, there is support for conducting research on these documents’ content, the effect they have on the organisation of Specialised Care and ... collected The correlation between quality of referral letters and outcome measures will then be tested The outcome measures that are found to have the strongest theoretical and empirical support for their...

Ngày tải lên: 11/08/2014, 16:20

... of the different definitions of prevention commonly used by other health care professions The term MC seems to cover both the concept of secondary and tertiary prevention [19] In the case of secondary ... KJ, FL, PWL and AR were involved in the design, supervision of data collection and the analysis of data CLY and IJ were supervising the study process and were involved in the analysis and manuscript ... if the frequency of previous events of LBP is used in the clinical decision process for secondary prevention, and 2) if the level of improvement is taken into consideration in the case of tertiary...

Ngày tải lên: 13/08/2014, 14:20

... slow the economy Therefore, we may conjecture that the relationship between default risk and interest rates is sensitive to some measure of where the economy is in the business cycle and/ or other ... over the change in the 10-year Treasury bond yield, the change in slope (defined as the difference between 10-year and 2-year Treasury bond yields), the convexity, the change in leverage, the ... BBB and maturities ranging from intermediate to long-term They find the relation between credit spreads and interest rates (level and slope) differ based on the maturity, credit ratings, and the...

Ngày tải lên: 26/10/2012, 11:21

... general statement about the relative strengths of SHãããO and NHãããS On the other hand, it would be fair to claim that the CHãããO H-bond is weaker than either of the other two Note, however, that ... from the NHãããS H-bond Rather than the CS antibond, the SS s* orbital is the recipient of charge in the next minimum m, this time extracted from both the N lone pair and the CO p* orbital An Nlp ... CHãããO The pattern changes when the H of the SH group is replaced by a second methyl group in CH3SCH3 The enhancement of the S atoms proton-accepting ability strengthens the NHãããS H-bond to the...

Ngày tải lên: 16/12/2012, 15:21

... three-digit random numbers and served under identical conditions to the trained descriptive testing Consumers ranked the three cheeses in their order of preference, and then evaluated them using ... compared with the other cheeses (7- and 12-month) The 12-month-ripened cheese had the lowest mean score of liking of 5.75, which is categorized as between “like slightly” and “neither like nor ... AGED 7, AND 12 MONTHS acid, diacetyl and methional In the aroma attribute terms used in the descriptive analysis, these can be described as “free fatty acid,” “buttery” and “sulfur” aromas The principal...

Ngày tải lên: 03/04/2013, 21:06

... performance and thus stock price decreases is not conducive to stockholder theory and implies that in agency theory there is a conflict of interest between the CEO and the shareholders they represent Other ... in the null and alternative forms Statistical analysis allows the researcher to either accept or reject the null hypotheses The null and alternative hypotheses for this study are: H01 (null) There ... stockholder theory and agency theory as the foundation for its approach and consequently is limited by the theory itself According to Veliyath and Bishop (1995), agency theory predicts that there is...

Ngày tải lên: 11/09/2013, 11:44

Ngày tải lên: 13/02/2014, 12:20

... changes in the level and the slope I measure the level of the Treasury term structure with the three-month Treasury bill yield, denoted YT,104, t , and measure the slope with the spread between the ... relation between yield spreads and the slope of the Treasury term structure is weaker, and the thirty-year yield no longer summarizes the relevant information in the term structure The hypothesis ... rating and maturity band The x ~4! test of equality of bs, i, m,1 and bs, i, m,2 across the three sectors is reported in the final column of Table II The x test does not reject the hypothesis...

Ngày tải lên: 06/03/2014, 04:20

... companies from the rest of the pack They are in a position to view their marketing mix in the form of 4+1P and 1R, and thereby customize their offerings to the rural market Further, to ensure ... wells, handpumps and ponds For the first in the history of advertising - these were branded Special stickers were put on the handpumps, the walls of the wells were lined with advertising tiles and ... is the application of the marketing concepts and not the concepts themselves that need to be looked at Often, in the rural marketplace it is the application of these concepts which differs the...

Ngày tải lên: 08/03/2014, 02:21

... reason, the research focuses on understanding the value of the corporate culture, in particular, understanding the relationship between the corporate culture and the innovation of management accounting ... made to obtain the generalization and percentage of asked managers and accountants for different choices and opinions This is also the primary data The finding of this survey is the primary source ... from secondary source, with an aim to ensure the accuracy and reliability of the data, the author performs reconciliation between the data received and specific information disclosed in the company...

Ngày tải lên: 13/03/2014, 14:20

... binding GST-IjBa in the presence and absence of ATP, and the value of a indicates whether the binding of one substrate (ATP) affects the afnity of the enzyme for the other substrate (GST-IjBa) [59] ... wells and the plates left to incubate for 15 The plates were inverted to remove the detergent after the 15 incubation period and the wells were washed twice with wash buffer by inverting the plates ... vitro and in silico analysis of the data The plot shows nuclear NF-jB oscillation in the original model and in the updated model with newly measured kr1, ka1 and kd1 for IKKIjBa complex (D) In the...

Ngày tải lên: 16/03/2014, 11:20

... of the organization and the licensing practice of the pool.55 Surprisingly enough, however, at this level the Commission tends to ignore the link between the exclusivity and standardization, and ... on the combination of the principles that, on the one hand, the market of reference for the territorial exercise of national intellectual property is the entire Internal Market, and, on the other, ... ancillary restraints accompanying one or the other of the items mentioned In addition, neither the Notice nor the Guidelines take sufcient account of the position of the sub-contractor, nor is it clear...

Ngày tải lên: 16/03/2014, 12:20

... spectra and in the rest of the mutants the probe was not significantly affected by the sTF–FVIIa complex formation As the purpose of our study was to map the interaction between FXa and sTF in the ... sTF and the effect of the modified sTF–FVIIa complex on FX activation In another study [17], these authors also examined the interaction between FXa and sTF–FVII in a similar way by observing the ... with sTF in the quaternary complex Residues E99 and L104 are located in the TF1 domain, and T197 is situated in the N-terminal portion of the TF2 domain, i.e close to the TF1 domain at the level...

Ngày tải lên: 17/03/2014, 03:20

... with the differences discussed in the text 27 The 17 in the sample of movers The key is that Plantinga and Bernell study nlsy79 respondents between 1996 and 2000, rather than between 1988 and ... particular First, the physical characteristics of the built environment, such as the separation between residences and the ease with which one can walk between them, and second, the neighborhood ... relationship between the residential landscape and weight because we measure the wrong aspect of landscape There are three reasons to believe that this is not a problem First, the existing literature and...

Ngày tải lên: 19/03/2014, 11:20

... controversy exists whether these are the patients who have early-stage disease and would benefit from detection or whether these are the patients who have indolent forms of prostate cancer Therefore, recommendations ... phenomenon, the other problem was the lack of calibration against a universal standard In an effort to standardize PSA methods, the World Health Organization (WHO) developed a standard, the WHO (90:10) ... including bleeding and infection Prostate cancer treatment often causes incontinence and impotence For these reasons, it is important that the benefits and risks of diagnostic procedures and treatment...

Ngày tải lên: 21/03/2014, 12:19

... of the author WHAT YOU’LL LEARN: A modern definition of brand The five disciplines of brand-building READY? LET’S START BY DISPELLING SOME MYTHS FIRST A brand is not a logo SECOND A brand ... a brand have a dollar value? AND HOW THIS SELECTION FROM INTERBRAND’S TOP 100 LIST SHOWS WHY BRANDS ARE WORTH PROTECTING: 2001 % CHANGE BRAND VALUE BRAND VALUE BRAND VS AS % OF NAME ($MM) PREVIOUS ... BILLION WITHOUT THE BRAND, COKE’S GLASS WOULD BE HALF EMPTY COKE’S MARKET CAP, NOT INCLUDING BRAND VALUE: $50 BILLION PREDICTION BRAND WILL BECOME THE MOST POWERFUL STRATEGIC TOOL SINCE THE SPREADSHEET...

Ngày tải lên: 22/03/2014, 14:20

... blood flow and effects from other neighboring cells and matrix The biophysical aspects of the endothelium through which the leukocytes transmigrate, in addition to the biophysical aspects of the leukocytes ... throughout the body of the cell, and the substrate at the basal surface of the ECs Interestingly, forces acting at one surface may be propagated internally or even to other surfaces of the cell, or they ... In (A), the force acting on the EC (black arrow) has components both in the direction of shear stress and in the direction of pulling by leukocytes In (B), the force on the EC is in the direction...

Ngày tải lên: 22/03/2014, 21:20

... weighted average of the real interest rate and the real exchange rate, where the weight on the exchange rate, !, depends solely on the elasticities of aggregate demand to the exchange and interest rate ... appreciation The interest rate hike puts a limit to the increase in aggregate demand, while also being instrumental to the strengthening of the exchange rate via the UIP schedule The latter strengthening ... line with the backward-looking nature of et in (15) The initial interest rate increase o¤sets the excess demand in the goods market and thereby the in‡ ationary pressures stemming from the shock...

Ngày tải lên: 22/03/2014, 23:20