... -casein sl examples are all concerned with variants of either bovine or caprine a The affected exons are exon in bovine a A [27, 38] and caprine -casein sl a,,-casein G [23], and exons 9, 10 and ... alleles of Indian Bos indicus into African populations, including sub-populations of the taurine type N’Dama, but the Kuri was not included in their study As a matter of fact, crossbreeding with ... difference of 921.4 Da was indicative of a deletion of about eight amino acid residues RP-HPLC elution patterns of tryptic hydrolysates of a B and H showed the absence of one peak in a H as the -caseins...
Ngày tải lên: 09/08/2014, 18:21
... in TraM and TraM2 affinity for TraR These findings highlight complex strain-specific variation in the QS regulation of A tumefaciens strains - XIV Chapter Introduction 1.1 Quorum sensing in bacteria ... 1996; Chai and Winans, 2005; Hwang and Farrand, 1994; Pappas and Winans, 2003; Zhu and Winans, 1999) Once bound to the tra-box, TraR directly interacts with the C-terminus of the α-subunit of the ... is agrocinopines and its receptor is AccR In absence of agrocinopines, AccR binds to its target DNA region and represses the transcription of traR and the genes required for agrocinopine catabolism...
Ngày tải lên: 14/09/2015, 12:07
Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx
... start of exon resulting in loss of the AUG initiating translation of the 88 kDa isoform We specifically point out that differential utilization of exon vs exon in splice variants introduces differing ... sites initiating biosynthesis of the 88, 77, 74 and 63 kDa iPLA2c isoforms Instead, based on current information about iPLA2c and its splicing, the first in- frame AUG site is downstream of the ... staining patterns (comparing and 2) and by the yellow color resulting from combination of green and red fluorescence in that iPLA2c is localized, in large part, to the mitochondrial compartment in...
Ngày tải lên: 19/02/2014, 16:20
Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites potx
... following subcutaneous injection of 3,000 infective L3 larvae Adults were recovered by Baermannization in saline at 37°C, washed × in saline and × in RPMI1640 containing 100 µg/ml penicillin and ... of whether secreted proteins of parasitic nematodes show accelerated evolution, and our results indicate that this is the case The predominance of predicted secreted proteins in the novel class ... existing entries), using a cutoff score of 80 in BLASTX (P < e-10) The number of ESTs bearing potential signal sequences was then calculated and the results are shown here (b) Effects of relaxing...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Modes of transmission and genetic diversity of foamy viruses in a Macaca tonkeana colony" potx
... Wickings EJ, BarreSinoussi F, Georges AJ, Georges-Courbot MC: Phylogenetic analysis of SIV and STLV type I in mandrills (Mandrillus sphinx): indications that intracolony transmissions are predominantly ... freeranging colony of monkeys, i e a group of 38 macaques (mostly adults) living in a temple in Central Bali, Indonesia In this case, the seroprevalence for FVs was of 89.5%, reaching 93% in adults ... the known modes of transmission for STLV-1; mainly from mother to child through breast-feeding In order to gain new insights on the timing of SFV infection, we undertook a longitudinal study with...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo sinh học: " Phenotypic and genetic variability of morphometrical traits in natural populations of Drosophila melanogaster and D simulans. I. Geographic variations" docx
... from n initial lines, n/2 new lines were produced and 10 individuals per line were measured In some cases, the new lines were generated and studied after the initial lines had been kept in the ... smaller and invest less into each offspring while Far Eastern populations develop more slowly, are larger and invest more energy into each individual (Taylor and Condra, 1980 and references therein) ... the Society Islands and Hawaii ; and populations in tropical Africa, the Seychelles and the Mascarene islands Between these main groups, we find populations living in regions with intermediate...
Ngày tải lên: 14/08/2014, 19:22
Báo cáo sinh học: " Phenotypic and genetic variability of morphometrical traits in natural populations of Drosophila melanogaster and D simulans. II. Within-population variability" pptx
... Means and standard deviations of intraclass correlations are given in table IV In both species, the observed and theoretical distributions are identical (not shown) and none of the comparisons using ... genetic architecture of wing length in natural populations is quite different from that of thorax length, with a predominance of non-additive effects due to dominance and epistasis Further investigations ... (measured in males) and female ovariole number variability could be more interesting from a biological point of view Phenotypic variability was also analyzed according to the geographic origin of the...
Ngày tải lên: 14/08/2014, 19:22
Báo cáo y học: "Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor" ppsx
... to differences in allele frequencies and genetic background To better understand the effect of HLA in RA in the Spanish population, we investigated the association of SE-containing HLA-DRB1 alleles ... to RA and then examined the possible protective effect of HLA-DR3 and DERAA-encoding alleles Finally, the effects of these alleles on the magnitudes of RF and ACPA production were determined study ... stratification, and new studies including greater numbers of patients are needed to clarify this effect HLA-DR3 and HLA DERAA-encoding alleles were associated with lower levels of ACPAs, and this finding...
Ngày tải lên: 12/08/2014, 12:20
Study of the spiramycin biosynthesis and its regulation in streptomyces ambofaciens
... use and transport of phosphate has been identified and inactivated in S lividans Its inactivation leads to reduced phosphate transport and increased biosynthesis of actinorhodin and prodiginins ... the incorporation of an amino acid The number and order of the modules of a NRPS thus generally determines the number of amino acids incorporated and the sequence of the peptide formed (Finking ... Streptomyces are used in the treatment of cancer: actinomycin D, anthracyclines (e.g daunorubicin, doxorubicin, epirubicin, pirirubicin and valrubicin) bleomycin, mitomycin C These compounds bind to DNA...
Ngày tải lên: 19/05/2016, 11:22
Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... Role of PKA in the mitochondrial targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches The first approach involved measuring the level of ... localized inside of the inner membrane Moreover, the imported + ⁄ 1A1 and + 33 ⁄ 1A1 proteins were extractable with alkaline Na2CO3 as shown in Fig 2C, suggesting that both proteins are localized in ... channel-forming proteins, TOM40 and translocase of inner membrane 23 (TIM23) [18–20] Our studies defined two distinct mechanisms of activation of cryptic mitochondria-targeting signals at the N-terminus of...
Ngày tải lên: 18/02/2014, 16:20
Báo cáo khoa học: Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants pdf
... a highly flexible ligand-binding pocket [34] Mutational analysis in the LBD of CfEcR showed that the ligand-binding pocket of this EcR is highly flexible and that a single amino acid substitu- FEBS ... format generally consist of a transcriptional activation domain fused to a DNAbinding domain (DBD) and a ligand-binding domain (LBD) The chimeric gene (transactivation domain– DBD–LBD) is expressed ... microgram of protein shown are the mean of three replicates ± SD (A,C) Fold induction values (B,D) shown were calculated by dividing RLUÆlg)1 protein in the presence of ligand with RLUÆlg)1 protein in...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... the difference in linking number of pBR322 in the respective sample and of pBR322 isolated from cells incubated for 30 with 0.1 mgámL)1 of coumermycin and 0.2 mgámL)1 rifampicin Topoisomerase ... esupercoilingI and esupercoiling , re¯ecting the sensitivity of transcription of topoisomerase I and DNA gyrase for DNA supercoiling Certain simpli®cations were made in [25], i.e grouping of transcription ... ®ts in Fig to an aLk of (corresponding to coumermycin inhibition) indicates a 2.8-fold induction Fusion of the topA promoters to the galactokinase gene showed a twofold to fourfold inhibition of...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo khoa học: Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans docx
... process of interest, allows genes to be ordered into pathways, and can provide important and novel mechanistic insights into the molecular structure and function of proteins In addition to forward genetic ... cytoplasm and functions as a chemical chaperone that aids in the refolding of misfolded proteins Loss of function of protein homeostasis genes also causes accumulation of damaged proteins and activation ... protein homeostasis are the largest class of rgpd genes (54 out of 122 total rgpd genes) These include genes that encode proteins required for RNA processing, protein synthesis, protein folding and...
Ngày tải lên: 30/03/2014, 03:20
báo cáo hóa học: " Leader (L) and L* proteins of Theiler''''s murine encephalomyelitis virus (TMEV) and their regulation of the virus'''' biological activities" docx
... and urinary incontinence The demyelination mainly affects the spinal cord, with an unexplained sparing of the cerebellar hemispheric white matter These pathological findings are reminiscent of ... subgroup strains of TMEV infect mainly neurons during the acute stage of infection [1-4] It is of interest that DA viral antigen and RNA that are present in neurons during the acute stage of infection ... cleavage of the p220 component of the cap-binding protein complex [32], resulting in the shut off of host protein synthesis On the other hand, the function of L of the cardioviruses is not well defined...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo sinh học: "Adaptive evolution of centromere proteins in plants and animals" ppt
... DNAbinding proteins would maintain an interface with the conserved kinetochore machinery Indeed, regions of CENP-C that show evidence of positive selection include DNAbinding and specificity regions, in ... Comparisons of CENP-C proteins in animals, yeast and plants The CENPC motif and conserved regions found at the termini of CENP-C proteins are indicated For pairwise comparisons of protein-coding sequences, ... evolution of DNA-binding specificity in these regions Targeting of native CENP-C proteins depends on other centromere proteins that vary according to species [45], but the dependence of CENP-Cs...
Ngày tải lên: 06/08/2014, 18:21
Báo cáo khoa học: "Genetic determination of vessel area in oak (Quercus robur L and Q petraea Liebl): a characteristic related to the occurrence of stem shakes" docx
... Commission of the European Communities under the project title «Genetics and breeding of (1986) Oak breeding in Germany; experiences and problems In: Proceedings IUFRO Joint Meeting of Working Parties ... Burley J (1982) Genetic variations in wood properties In: New Perspectives in Wood Anatomy (Baas P, ed), Martinus Nijhoff, The Hague, 151-169 Cinotti B (1991) Recherche de propriétés intrinsèques du ... determine provenance variations in vessel size; 2) estimate the heritability of vessel size; and 3) to find a means of recognizing shake-prone trees so that they could be removed during early thinning...
Ngày tải lên: 08/08/2014, 19:21
Báo cáo khoa hoc:" Genetic parameters of dairy traits in the Alpine and Saanen goat breeds" pptx
... production and protein content was a limiting factor in the highly productive Alpine and Saanen breeds The selection ment of programme relies on the use of milk recording and artificial insemination in ... milk, fat and protein yields, fat and protein contents, in the Alpine and Saanen populations using an animal model MATERIALS AND METHODS 2.1 Data First lactation records of Alpine and Saanen ... breeds, point estimates suggest that the potential for genetic progress in PC and PY might be somewhat higher in the Alpine breed and the potential for joint progress in FC and milk and fat yields...
Ngày tải lên: 09/08/2014, 18:21
Báo cáo sinh học: "Genetic variation of traits measured in several environments. I. Estimation and testing of homogeneous genetic and intra-class correlations between environments" ppt
... to thank I Olivieri and D H6bert (INRA-Montpellier) for providing the data set and raising the issue of estimation and testing genetic parameters in experiments of this kind REFERENCES Callanan ... A[’,’] and 0, u[2 t return to (10a!, and o, back into Elt] (e!ei) of !lOc! 0; (5) solve for a, ; and (6) for a second inner cycle yielding À (J!!t,2] and (J;J and continue 2] , [t 2] , t [lOb] and ... i’ and Cov(b2!, bi!!!) for j ! j’ and any i and i’; and e is a residual effect pertaining to the kth individual jk in the subclass ij, assumed normally and independently distributed with mean and...
Ngày tải lên: 09/08/2014, 18:21
báo cáo khoa học: "On the genetic determinism of muscular hypertrophy in the Belgian White and Blue cattle breed" pptx
... according genetic determinism to In the experiment we report in this paper, the degree of muscling was evaluated by the total weight of the most important muscles So in this study, a well defined ... copy of the mh gene having a distinctly smaller effect than both copies (fig 3) The degree of overlapping of the distributions corresponding to the genotypes MA/+ / and mhlmh is quite small and of ... characteristic : the case of the Belgian Blue Breed In : K J.W.B and M F (ed.), Muscle hypertrophy of genetic ING ENISSIER origin and its use to improve beef production, 437-449 Martinus Nijhof, The Hague...
Ngày tải lên: 09/08/2014, 22:23
báo cáo khoa học: "Structure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence for the existence of two divergent classes of SUN proteins in plants" pot
... nuclei contain multiple different SUN-domain proteins Models of the Topology of Plant SUN-domain Proteins The two structural classes of plant SUN-domain proteins found in maize, and shown to ... nucleotides in size Properties of Maize SUN-domain Proteins Using the full-length cDNAs listed in Table we predicted the encoded proteins for five different maize SUN-domain proteins Their features and ... homology) proteins as part of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex [13,37-43] The other members of the KASH-domain family are proteins with cytoplasmic domains and nuclear lamins...
Ngày tải lên: 11/08/2014, 11:21