bcs in developing poorly water soluble drugs

... (cs−ct), resulting in low dissolution rates This, in turn, causes many problems in vivo when poorly soluble drugs are administered via various routes of administration Poorly soluble drugs that are ... lecithin in the small intestine allowing for micellar solubilization of the drug In addition, an Route-Specific Challenges in the Delivery of Poorly Water- Soluble Drugs Table 1.1 Pharmacokinetic ... develop a poorly water- soluble drug has become essential Gaining a detailed understanding of a compound through preformulation studies can be especially challenging for poorly water- soluble drugs...

Ngày tải lên: 05/03/2014, 11:20

... contents within the large intestine could interfere with the determination of rectal temperature which would increase the variance of the temperature readings Body temperature was determined using a ... rota-rod test is usually used to examine possible deficits in motor function including motor incoordination and ataxia in rodents [2] Mice were placed on a rotating rod (12 cm wide; cm diameter) ... temperature A single clinical dose of BV is µg/kg when administered by either an intradermal or subcutaneous route in human patients in Korea Since BV subfractions have not been administered to...

Ngày tải lên: 07/08/2014, 18:20

... greatly increased in water- stressed plants (+76%) It is unlikely that this increase in soluble carbohydrate reflected a direct inhibition of phloem loading in response to water deficits (Hoddinot ... that soluble carbohydrates may act as osmotic solutes and contribute to osmoregulation in water- stressed increases in hexose concentrations in water- stressed oak leaves may indicate that these soluble ... hydrolysis in waterstressed leaves (Jones et al, 1980) and/or a change in the partitioning between starch and sucrose synthesis (Vassey and Sharkey, 1989) In spinach, this change in the partitioning...

Ngày tải lên: 08/08/2014, 18:21

... supply systems in developing countries.11 Rainwater In developing countries rainwater is sometimes used to supplement the other water supply sources In some tropical islands rainwater is the only ... C016_008_r03.indd 1004 11/18/2005 11:01:57 AM PLANNING WATER SUPPLY AND SANITATION PROJECTS IN DEVELOPING NATIONS the financial (minimizing initial investment cost as well as maintenance cost) ... water supply systems in developing countries, Journal of Water Resources Planning and Management, July 1987, p 485 Witt, Vicent M., Developing and applying international water quality guidelines,...

Ngày tải lên: 10/08/2014, 20:20

... alternative drinking water schemes in contributing to increased sustainable access in rural and periurban settings of developing nations cannot be overemphasized [18] One of such local interventions in ... necessary changes take effect in the packaged water industry [37] Accra, Ghana A rapidly emerging water vending business in Ghana has been that of vending sachet water or bagged water, which is a cheaper ... actually using safe drinking water is likely to be lower than that using the globally recognized ‘improved’ drinking water sources Going by the ‘exclusion criteria’ and the ‘official indicators’,...

Ngày tải lên: 11/08/2014, 14:21

... apparatus required for obtaining samples by coring or sawing is described in ASTM C 42.§ Sampling by drilling is not applicable for this test and shall not be used 3.2—Sample processing apparatus: 3.2.1 ... method described herein should be used when chloride-bearing aggregates influence the results obtained using ASTM C 1218 2.2—Sulfides are known to interfere with the determination of chloride ... Proceed in accordance with the reference ASTM C 114, starting with the procedure specified in Section 19.5.3 and continuing to the end of Section 19.5.8 7.2.3 Make a blank determination by using...

Ngày tải lên: 24/10/2014, 17:40

Ngày tải lên: 07/11/2012, 14:21

... V.2.Recommendation…………………………………………………………………… ……30 V.2.1.Selecting and evaluating the texts……………………………………………… ……30 V.2.2 Suggested techniques for integrating short stories and poems in the teaching of reading comprehension skills………………………………………………………… ... texts……………………………….………………19 IV.2.The effects of short story and poem in teaching reading comprehension….………22 Chapter V Conclusion and Recommendation………………………………… ………30 V.1.Introduction………………………………………………………………………… …….30 ... II.3.1 Some links between reading skills and literary skills…………… ……………… 13 II.3.2 Efferent reading and aesthetic reading……………………………….………………14 Chapter III: Methodology……………………………………………………………………15...

Ngày tải lên: 07/11/2012, 14:21

... values of literature in language teaching • Integrating short stories and poems in teaching reading comprehension • Introducing techniques to integrate literary texts reading comprehension class ... definitions introduced here, which seem very interesting, are introduced by Baurain (2005)  Poetry: “still picture”, showing a meaning  Story: “moving picture”, discovering meanings in actions ... in the three main fields: • Texts selection and evaluation • Suggested techniques for integrating short stories and poems in developing reading skills • Keys for using literary texts in reading...

Ngày tải lên: 07/11/2012, 14:21

... figurative meanings in the poem □ I think understanding the content is enough □ This activity is interesting, we can look at different features of the event □ It is helpful, we can think in our own ... Predicting plot of story or poem □ I find it of no use □ It is interesting and promotes our creativity □ Others……………………………………………………………… c Answering comprehension questions □ It is boring and ... Questionnaires on the effects of short story and poem in teaching reading comprehension Which of the followings you find most difficult when reading short stories and poems: a unclear theme b vocabulary...

Ngày tải lên: 07/11/2012, 14:21

... Pointing out the values of literature included short stories and poem in language teaching and finding the way to integrate short stories and poems into the reading classroom to develop reading ... using short stories and poems in teaching and learning reading Method of collecting data:  At the end of term, weeks before the final exam Results and Findings  Results:  Pointed out that integrating ... teaching reading comprehension Introduce techniques to integrate literary texts in the reading class Scope:   The importance of learning English in the industrial world The situation of learning and...

Ngày tải lên: 07/11/2012, 14:21

... 9840238 THE INFORMAL SECTOR IN SOLID WASTE MANAGEMENT IN DEVELOPING COUNTRIES The motivation for recycling in developing and industrialised countries is rather different In the latter recycling is ... contributions of the informal sector for solid waste management in developing countries in general and in HCMC in particular and to find out whether an integration of the informal sector in the formal ... IN DEVELOPING COUNTRIES II.6 Problems of SWM in developing countries ZURBRUGG (2002) identifies four typical problem areas for SWM in developing countries: • Inadequate service coverage and inefficiencies...

Ngày tải lên: 24/08/2013, 18:48

... of sustainability, or of threats to sustainability In order to this, proper sustainability criteria/indicators must provide this information, to indicate our progress in achieving sustainability ... survey, the local people in the community are now simultaneously using three sources of water (rainwater, drilled well water, and hand-dug well water) for cooking, drinking and domestic purposes ... unhygienic latrines with a bad smell Wastewater is disposed directly into the river No water drainage system is constructed in the community; wastewater runs into side drains or is absorbed into the...

Ngày tải lên: 05/09/2013, 10:15

... exchanging information in their domain (music, chemistry, electronics, hill-walking, finance, surfing, petroleum geology, linguistics, cooking, knitting, stellar cartography, history, engineering, ... book’s printing; the rightmost single-digit number is the number of the book’s printing For example, the printing code 01-1 shows that the first printing of the book occurred in 2001 Composed in Bembo ... analyser, including the PCB design, operating system, and application software Soon afterward, while developing man-machine interfaces, the prerelease version of Borland Delphi turned Westy into a Windows...

Ngày tải lên: 14/12/2013, 22:15

... so that it does not start in a separate window but instead uses the same window in which you are entering your commands.You can that by entering the following command instead of the startup command ... chapter mainly discusses Xerces and Xalan 1, while noting some differences you will encounter in Xerces and Xalan In Section 4.5, “Installing Xalan,” you can find some information about using Xalan ... (pun intended) A good resource for learning about scope is available at http://developer.java.sun.com/developer/onlineTraining/JSPIntro/ contents.html Another way to start learning about scope in...

Ngày tải lên: 14/12/2013, 22:15

... string into a request parameter.You can test this by putting it into an HTML form input element.Try pasting “doubly escaped” XML strings like the one used in the previous example into a form input ... (not needed) host increases rating host_increases_rating host_increases_rating host decreases rating host_decreases_rating host_decreases_rating bonForum bonForum bonForum Requesting the Next JSP ... element and posting that to your servlet Your Java servlet must then something like the following to get the XML back into a string: String sXML = (String)request.getParameter(“paramXML”); In the next...

Ngày tải lên: 14/12/2013, 22:15

... of activity When a session expires, all information in its user context becomes inaccessible n n n In addition to maintaining user-related information in storage locations with session scope, ... ratings 6.6.1 Rating a Guest Host actors can control the rating of the guests in their chat, incrementing or decrementing the value New guests begin with a status of If a guest reaches a rating ... Troubleshooting If you are having insoluble problems with a Tomcat Web app you are developing, try down shutting Tomcat, deleting its work folder with all the work files it needs, and then restarting...

Ngày tải lên: 14/12/2013, 22:15

... Synchronizing the XML database Finding chat and actor status in chat Rejoining a chat Joining a chat I I I I I I I Adding a guest actor Joining a chat, continued Handling chat messages Setting serviceStatus ... Topic Performing thread synchronization Synchronizing the XML database Finding the chat and actor status in Chat Rejoining existing chats Starting a chat Adding a host actor Adding a chat element ... method code first looks for the max inactive interval (in minutes), a ServletContext attribute string called sessionMaxInactiveMinutes Failing that, it looks in an initialization parameter of the...

Ngày tải lên: 14/12/2013, 22:15

... listing above in the section “Joining a Chat.”There is also some discussion of the method call in both that section and in the section “Joining a Chat, Continued.” The method is called as in this ... might as well get it right at the beginning because if something is wrong here, nothing else needs doing.Without a chatNode, there is not much point in joining a chat! You can see here how the ... see both these methods in action in the same source code listings as the method covered in the last section Refer to the sections “Rejoining Existing Chats” and to “Passing Information Between Sessions.”...

Ngày tải lên: 14/12/2013, 22:15

... String value ) { if( !loggingInitialized ) { logging = pageContext.getServletContext( ).getInitParameter( “Logging” ➥); logODI = new BonLogger( “OutputDebugInfoTagLog.txt”, logging ); loggingInitialized ... setType(String value) { if(!loggingInitialized) { logging = pageContext.getServletContext( ).getInitParameter( “Logging” ); logTT = new BonLogger( “TransformTagLog.txt”, logging ); loggingInitialized ... use.These classes are TagAttributeInfo, TagData, TagExtraInfo, TagInfo, TagLibraryInfo, and VariableInfo The doStartTag( ) Method Implementing the Tag interface implies defining a doStartTag() method...

Ngày tải lên: 14/12/2013, 22:15