b 47 hours and earnings in private nonagricultural industries 1960 2007
báo cáo khoa học: "Cationic nanoparticles for delivery of amphotericin B: preparation, characterization and activity in vitro" potx
Ngày tải lên :
11/08/2014, 00:22
... (A) and zeta-potential (B) for DODAB BF/AmB/ CMC/PDDA assemblies Final DODAB, AmB and CMC concentrations were mM, 0.005 mM and mg.mL-1, respectively Interaction time between DODAB BF/AmB and ... CMC and PDDA ≥ mg/mL, AmB/DODAB BF/ CMC/PDDA assembly contained AmB in the aggregated state forming drug particles sequentially covered by DODAB BF, CMC and PDDA yielding also 0% fungus viability ... AmB in water DODAB BF DODAB BF/AmB DODAB BF/AnB/CMC 1 1 0.005 0.005 0.005 0.005 0.005 0.01 0.1 433 ± 79 ± 79 ± 88 ± 145 ± 90 ± -26 ± 41 ± 42 ± 40 ± 32 ± -50 ± AmB in water AmB in IGP DODAB...
- 13
- 774
- 0
gender and justice in multicultural liberal states feb 2007
Ngày tải lên :
11/06/2014, 00:06
... acknowledging that minority groups will continue to be bound by liberal democratic laws in the public sphere, Okin worries that discrimination and oppression in the private realm will go unnoticed and ... Within both national minority and immigrant communities, the spectrum of vulnerable individuals is thus quite broad, and might include religious minorities within the group, gays and lesbians, individuals ... tractable, I argue, as they are made amenable to negotiation and compromise-based solutions INTERNAL MINORITIES AND DEMOCRATIC AGENCY The terms ‘internal minorities’ and ‘minorities within minorities’...
- 274
- 318
- 0
open university press teaching and training in post-compulsory education dec 2007
Ngày tải lên :
11/06/2014, 12:50
... for those involved in training in industry and commerce, in both the public and the private sectors Teaching and Training in Post-Compulsory Education is not intended as a textbook to be read from ... technology Initial Teaching Award Learning and Skills Industrial Training Board local authority lifelong learning Lifelong Learning UK Learning and Skills Council Learning and Skills Network Learning ... based on the standards were introduced in September 2007 The standards are a crucial element of any teacher-training programme and are broken down into six main domains: professional values and...
- 306
- 469
- 0
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 47) ppt
Ngày tải lên :
24/12/2013, 18:15
... preservatives and disinfectants In survived cases, in which boric acid had been taken by mistake or for suicidal purpose, the boric acid concentrations were 1–44 µg/mL in blood and 20 µg/mL in urine [3] In ... vomiting, diarrhea and abdominal pain is most common as observed in the above case; headache, scarlet fever-like exanthemas and desquamation of the skin are sometimes observed When the poisoning becomes ... spectrophotometric analysis of boric acid in a urine specimen, the value obtained may be slightly greater than the true value This is probably due to interference by a certain urinary element, which also...
- 5
- 234
- 0
Tài liệu Corporate Ownership structure and the Informativeness of Accounting Earnings in East Asia doc
Ngày tải lên :
18/02/2014, 01:20
... accounting studies (Ball, Kothari, and Robin, 2000; Ball, Robin, and Wu, 1999; and Ali and Hwang, 2000) have provided evidence that in addition to accounting standards, features of the institutional ... two-digit Standard Industry Classification system - 23 - the omitted expected earnings component When we include lagged earnings as expected earnings by replacing NI with the change in earnings (current ... transparency In this business environment, it is in the interest of both the controlling owners and the minority shareholders to release as little accounting information to the public as possible This information...
- 46
- 539
- 0
Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf
Ngày tải lên :
18/02/2014, 16:20
... was obtained by 15 of centrifuging at 240 g Blood from mice was collected and handled as described previously [3] Murine PRP was prepared by centrifuging blood at 280 g for min, and centrifuging ... thrombin alone The thrombin receptors PAR1 and PAR4 have been implicated in early and late stages of thrombin-induced human platelet activation, respectively To investigate whether PAR1 alone or in ... with the PKA inhibitors, KT5720 and H89 [28] Following saponin permeabilization, this resulted in increased InsP3-induced Ca2+ release with either inhibitor, with an EC50 of lm KT5720 and lm H89...
- 15
- 565
- 0
Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt
Ngày tải lên :
19/02/2014, 08:20
... chains Both have been implicated in the binding of ACP [2], probably by donating hydrogen bonds to one of the carbonyl oxygens in malonyl-ACP, thereby stabilizing charge 706 relocalization during ... albeit weak, binding of ACP to the docking site followed by a conformational change in ACP proposed to inject the acyl chain into the substrate-binding pocket [32] If a similar mechanism is involved ... ‘bulky’ mutants all point to the orientation of H333 and its hydrogen bond donor properties as being the cornerstone of obtaining and ⁄ or retaining residual decarboxylase activity The emerging...
- 16
- 450
- 0
Tài liệu Activity Data on Fundraising, Investments and Divestments by Private Equity and Venture Capital Firms in Europe 2012 ppt
Ngày tải lên :
19/02/2014, 09:20
... 2011 *Buyout funds including Growth capital and Mezzanine funds Fundraising Yearbook 2012 YearBook 2011 | Creating lasting value | 10 Generalists funds raised by type of investors 2007- 2011 - Incremental ... development and initial marketing Companies may be in the process of being set up or may have been in business for a short time, but not sold their product commercially • Later-stage venture: Financing ... 5.2% *Buyout funds including Growth capital and Mezzanine funds Fundraising Yearbook 2012 YearBook 2011 | Creating lasting value | 13 Generalist funds raised by type of investors 2011 - Incremental...
- 48
- 426
- 0
Tài liệu Báo cáo khoa học: Insulin/protein kinase B signalling pathway upregulates metastasis-related phenotypes and molecules in H7721 human hepatocarcinoma cell line pptx
Ngày tải lên :
21/02/2014, 00:20
... than that of PKB protein and activity in the insulin treated and S-PKB cells, indicating that SLex might be regulated by other insulin-induced factor(s) in addition to PKB signalling pathways It ... cells (C) PKB activity in sense or antisense PKB transfected cells before and after insulin treatment UnC, Mock, UnC + Ins or Ins, Mock + Ins, S-PKB, S-PKB + Ins, AS-PKB, AS-PKB + Ins, LY294002, ... differently treated and transfected cells (A) Expression of PKB protein and b- actin (loading control) in differently treated and transfected cells (Western blot) (B) PKB activity in insulin and LY294002...
- 11
- 615
- 0
Tài liệu Báo cáo Y học: Proteolysis of bovine b-lactoglobulin during thermal treatment in subdenaturing conditions highlights some structural features of the temperature-modified protein and yields fragments with low immunoreactivity pptx
Ngày tải lên :
21/02/2014, 15:20
... (blue, basic; green, hydrophobic) The disulfideforming Cys66 and Cys160 are in yellow ball and stick Structures were generated by using RASMOL [38], and coordinates in file 1B8 E deposited in the RCSB ... shown in Table 1, that apparently are better explained by assuming an inhibitory effect of the peptides produced by hydrolysis of BLG at high temperature Table Thermal stability of trypsin and ... hydrophobic) The disulfide-forming Cys66 and Cys160 are in yellow Structures were generated by using RASMOL [38], and coordinates in file 1BEB deposited in the RCSB Protein Databank [5] Fig ELISA assay...
- 11
- 526
- 0
Báo cáo khoa học: Docosahexaenoic acid stabilizes soluble amyloid-b protofibrils and sustains amyloid-b-induced neurotoxicity in vitro ppt
Ngày tải lên :
07/03/2014, 10:20
... protofibrils, and thereby maintaining Ab-induced toxicity in PC12 cells Results Unsaturated fatty acids stabilize Ab42wt protofibrils Fatty acids were incubated with Ab42wt in a physiologic buffer ... demonstrating the increased toxicity of soluble aggregates in comparison to insoluble aggregates In contrast, the toxicity induced by Ab42Arc incubated with DHA was indistinguishable from that induced ... soluble Ab in Tg2576 mice [9], indicating a shift from insoluble Ab to soluble species The present study demonstrates that DHA and AA stabilize soluble protofibrils, thus providing in vitro data in...
- 11
- 465
- 0
Báo cáo khoa học: Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of b-lactam antibiotics pptx
Ngày tải lên :
08/03/2014, 08:20
... penicillin G binds with the thiazolidine ring to the enzyme via hydrophobic interactions between the 2b- methyl group and aF146 and bF71 and hydrogen bonding between its carboxylate group and aR145:NH2 ... deacylation such information is more difficult to obtain since the individual rate and binding constants cannot be measured separately Some information may be obtained by performing nucleophile ... may bind in the acylbinding site of PA Hydrolysis of p-NPA may thus proceed via reversed binding of the substrate, in which the leaving group, p-nitrophenol, occupies the acyl binding site and...
- 9
- 518
- 1
Báo cáo khoa học: Identification and expression of the first nonmammalian amyloid-b precursor-like protein APLP2 in the amphibian Xenopus laevis ppt
Ngày tải lên :
16/03/2014, 16:20
... underline, while the transmembrane domains are indicated by a bold underline Domains encoded by alternatively spliced exons, the most N-terminal being a Kunitz type protease inhibitor (KPI) domain, ... present In intestine and stomach, and to a lesser extent in brain, liver and lung, APLP2 mRNA forms containing exon were also detectable (Fig 3, upper panel) In a similar way, the alternative splicing ... Kamal, A., Stokin, G .B. , Yang, Z., Xia, C.H & Goldstein, L.S (2000) Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I Neuron...
- 7
- 405
- 0
Báo cáo khoa học: Proteomic identification of all plastid-specific ribosomal proteins in higher plant chloroplast 30S ribosomal subunit PSRP-2 (U1A-type domains), PSRP-3a/b (ycf65 homologue) and PSRP-4 (Thx homologue) doc
Ngày tải lên :
17/03/2014, 09:20
... poly(A)-binding protein, barley cold-inducible glycine-rich RNA-binding protein, Anabaena variabilis RNA-binding protein, human hnRNP, and human U1A snRNP) shows high conservation of the RNP1 and ... numbers: cpRNP, chloroplast ribonucleoprotein 28RNP from spinach (P28644); GRP, cold-inducible glycine-rich RNA-binding protein from barley (U49482); cyRBP, RNA-binding protein from a cyanobacterium, ... of psbA mRNA is regulated by cis-elements including ribosome-binding sites and 5¢-UTR-binding proteins [16–18] Thus, while maintaining an overall resemblance to the eubacterial system, chloroplast...
- 16
- 528
- 0
Báo cáo Y học: A polymer with a backbone of 3-deoxy-D-glycero -D-galacto -non-2ulopyranosonic acid, a teichuronic acid, and a b-glucosylated ribitol teichoic acid in the cell wall of plant pathogenic Streptomyces sp. VKM Ac-2124 pdf
Ngày tải lên :
17/03/2014, 10:20
... mono- and bisphosphates were identified as alkaline hydrolysis products Acid hydrolysis afforded ribitol monophosphates and bisphosphates, anhydroribitol phosphate, anhydroribitol, ribitol, inorganic ... Glucosylribitol phosphate was identified based on its electrophoretic mobility (pyridinium acetate buffer) in comparison with an analogous ester obtained upon alkaline hydrolysis of glucosylated ribitol ... group The interresidue cross-peak H-1 (B) /H-6(A) and H-1 (B) / H-6¢(A) in the ROESY spectrum at 4.90/3.98 and 3.88 p.p.m and the correlation H-1 (B) /C-6(A) at 4.90/ 69.40 p.p.m in the HMBC spectrum...
- 6
- 561
- 0
Báo cáo Y học: A b-lysine adenylating enzyme and a b-lysine binding protein involved in poly b-lysine chain assembly in nourseothricin synthesis in Streptomyces noursei pot
Ngày tải lên :
17/03/2014, 17:20
... gene of the b- lysine binding protein Total protein from the last puri®cation step of NpsB was subjected to preparative SDS/PAGE and the band representing the b- lysine binding protein was in- gel digested ... involve the participation of only one single stand-alone A-domain and a single binding protein NspB points to an iteration of these two proteins in the assembly line of poly b- lysine chains in ... stable complex with each other (not shown) To test the nature of the covalent bond between the binding protein and b- lysine, the b- lysine binding protein was charged with radioactive b- lysine and...
- 11
- 559
- 0
Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt
Ngày tải lên :
22/03/2014, 21:21
... determined by using anti (b- catenin) serum b- Tubulin served as loading control and nuclear marker (D) Macrophages were treated with LPS (100 ngÆmL)1) for 40 and stained with anti -b- catenin and DAPI ... analyzed for b- catenin using western blotting (B) Cells were fixed and stained with anti- (b- catenin) serum and DAPI and observed using fluorescent microscopy (C) Nox1 mRNA was analyzed by RT-PCR (D–F) ... 2010 FEBS J.-S Kim et al expression Our results showing the possibility of the Nox1 gene being regulated by GSK 3b ⁄ b- catenin are original and lead to the possibility that GSK 3b ⁄ b- catenin may...
- 8
- 340
- 0
Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
Ngày tải lên :
23/03/2014, 15:21
... point is the average of four Sfbgly50 activity determinations using mM MUbglc as substrate The pH stability of the recombinant Sfbgly50 (n) was checked by incubating the enzyme in the same buers ... Recombinant Sfbgly50 was puried by a combination of hydrophobic and anion-exchange chromatography (Fig 2B) , resulting in a 50% recovery and a yield of about 0.2 mg puried Sfbgly50 from 0.5 L bacterial ... 7.08.0; 50 mM Bicine buffer 7.08.5) The pH stability of Sfbgly50 was checked by incubation in the same buffers for a time equal to the assay time and then determining the activity remaining at the...
- 10
- 522
- 0